Topiramate in Migraine Prevention
... Clarify Diagnosis:- History is taken, not given. Explain what it means to the patient. Assess the burden to the patient. Establish what the patient expects. Be clear what the Physician can offer; limited! Advise on areas where the patient can intervene. Optimise the treatment of acute attacks. Plan ...
... Clarify Diagnosis:- History is taken, not given. Explain what it means to the patient. Assess the burden to the patient. Establish what the patient expects. Be clear what the Physician can offer; limited! Advise on areas where the patient can intervene. Optimise the treatment of acute attacks. Plan ...
skeletal muscle relaxants
... Mechanism of Sk. muscle contraction Initiation of impulse Release of acetylcholine Activation of nicotinic receptor at motor end plate Opening of ion channel, passage of Na+ , depolarization of end plate ...
... Mechanism of Sk. muscle contraction Initiation of impulse Release of acetylcholine Activation of nicotinic receptor at motor end plate Opening of ion channel, passage of Na+ , depolarization of end plate ...
L1-skeletal muscle r..
... As potent as curare (1.5) Has intermediate duration of action (30 min). Eliminated by non enzymatic chemical degradation in plasma (spontaneous hydrolysis at body pH). used in liver failure & kidney failure (drug of choice). Liberate histamine (Transient hypotension), bronchospasm. Anti-histamine ...
... As potent as curare (1.5) Has intermediate duration of action (30 min). Eliminated by non enzymatic chemical degradation in plasma (spontaneous hydrolysis at body pH). used in liver failure & kidney failure (drug of choice). Liberate histamine (Transient hypotension), bronchospasm. Anti-histamine ...
ANTIGLAUCOMA MEDICATIONS
... • decreases with increasing concentrations, and the greater amount of drug lost in the lacrimal drainage system increases the potential for ...
... • decreases with increasing concentrations, and the greater amount of drug lost in the lacrimal drainage system increases the potential for ...
Drugs Salbutamol (Ventolin) SLB
... Expiratory wheezing associated with allergy, anaphylaxis, smoke inhalation or other lower airway cause. ...
... Expiratory wheezing associated with allergy, anaphylaxis, smoke inhalation or other lower airway cause. ...
Antiemetic drugs
... • Neurokinin 1 (NK1) receptor antagonist on nucleus of tractus solitaries and Visceral afferent nerves • So it prevent both peripheral and central stimulation of the vomiting center Uses as antiemetic: • In combination with 5-HT3 blockers to treat vomiting due to cancer chemotherapy Adverse effects: ...
... • Neurokinin 1 (NK1) receptor antagonist on nucleus of tractus solitaries and Visceral afferent nerves • So it prevent both peripheral and central stimulation of the vomiting center Uses as antiemetic: • In combination with 5-HT3 blockers to treat vomiting due to cancer chemotherapy Adverse effects: ...
6-作用于神经系统的药物
... 2. Clinical uses: (1)All depression The curative effects are well to endogenous(内源性), reactive, and involutional(更年期) depression . Depressive state of schizophrenia, the curative effect is bad. ...
... 2. Clinical uses: (1)All depression The curative effects are well to endogenous(内源性), reactive, and involutional(更年期) depression . Depressive state of schizophrenia, the curative effect is bad. ...
fff-Antipsychotics (Neuroleptics)
... Isosteric replacement of N atom of phenothiazine with sp2 carbon (methylidene) led to thioxanthenes. Thioxanthenes are also nonpolar in which substituent at 2position led to formation of either cis (Z) or trans (E) isomers. Z isomer is more active than trans isomer or its saturated analog because it ...
... Isosteric replacement of N atom of phenothiazine with sp2 carbon (methylidene) led to thioxanthenes. Thioxanthenes are also nonpolar in which substituent at 2position led to formation of either cis (Z) or trans (E) isomers. Z isomer is more active than trans isomer or its saturated analog because it ...
CLONIDINE PREMEDICATION AND ANESTHETIC EFFECTS
... Provides favorable cardiovascular effects by reducing catecholamine levels, therefore lowering heart rate and blood pressure during anesthesia (however, has not been shown to reduce perioperative ischemia) Decreases postoperative oxygen consumption When compared with oral midazolam, clonidine was le ...
... Provides favorable cardiovascular effects by reducing catecholamine levels, therefore lowering heart rate and blood pressure during anesthesia (however, has not been shown to reduce perioperative ischemia) Decreases postoperative oxygen consumption When compared with oral midazolam, clonidine was le ...
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... alone B. Initiate therapy with HCTZ alone C. Initiate therapy with amlodipine alone D. Initiate therapy with HCTZ and amlodipine ...
... alone B. Initiate therapy with HCTZ alone C. Initiate therapy with amlodipine alone D. Initiate therapy with HCTZ and amlodipine ...
Lecture presentation - TMA Department Sites
... their condition. • Encourage fluid intake (up to 3000 mL per day) if permitted. • Educate about proper dosing and equipment care. Salmeterol is indicated for PREVENTION of bronchospasms, not management of acute symptoms. ...
... their condition. • Encourage fluid intake (up to 3000 mL per day) if permitted. • Educate about proper dosing and equipment care. Salmeterol is indicated for PREVENTION of bronchospasms, not management of acute symptoms. ...
Muscle Relaxants
... released at the neuromuscular junction to bind with the ACh receptors on the postsynaptic membrane of the motor endplate They therefore block the action of ACh and prevent depolarisation. ...
... released at the neuromuscular junction to bind with the ACh receptors on the postsynaptic membrane of the motor endplate They therefore block the action of ACh and prevent depolarisation. ...
utilization management criteria
... clinical worsening. Limitation of Use: Adding sildenafil to bosentan therapy does not result in any beneficial effect on exercise capacity. Tracleer is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability and ...
... clinical worsening. Limitation of Use: Adding sildenafil to bosentan therapy does not result in any beneficial effect on exercise capacity. Tracleer is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability and ...
Skeletal Muscle Relaxants Dr Naser Ashraf Skeletal Muscle
... release potassium in blood Succinylcholine apnoea Malignant hyperthermia: when used alng with halothane in general anaesthesia ...
... release potassium in blood Succinylcholine apnoea Malignant hyperthermia: when used alng with halothane in general anaesthesia ...
How to manage Correspondence
... largely resulting in increased clearance and decreased pharmacological effect.The increased glomerular filtration rate associated with pregnancy will enhance the apparent oral clearance of drugs such as atenolol, the primary disposition of which is dependent on renal filtration [11]. Calcium channel ...
... largely resulting in increased clearance and decreased pharmacological effect.The increased glomerular filtration rate associated with pregnancy will enhance the apparent oral clearance of drugs such as atenolol, the primary disposition of which is dependent on renal filtration [11]. Calcium channel ...
PRODUCT MONOGRAPH Pr INDERAL®-LA (Propranolol
... maintaining the heartbeat has also been reported. For these reasons, INDERAL-LA should be withdrawn gradually from patients scheduled for elective surgery, following the recommendations provided in WARNINGS, Abrupt Cessation of Therapy. According to available evidence, all clinical and physiologic e ...
... maintaining the heartbeat has also been reported. For these reasons, INDERAL-LA should be withdrawn gradually from patients scheduled for elective surgery, following the recommendations provided in WARNINGS, Abrupt Cessation of Therapy. According to available evidence, all clinical and physiologic e ...
Anti Epileptic Drugs
... • Rash especially if valproate is also given, if starting dose is high or if dose escalation is rapid (Rash may disappear despite continued ...
... • Rash especially if valproate is also given, if starting dose is high or if dose escalation is rapid (Rash may disappear despite continued ...
cardiovascular drugs and autacoids
... which works by stimulating release of nitric oxide and prostacyclin The hypotensive activity of captopril results both from an inhibitory action on the reninangiotensin system and a stimulating action on the kallikrein-kinin system The latter mechanism has been demonstrated by showing that a bradyki ...
... which works by stimulating release of nitric oxide and prostacyclin The hypotensive activity of captopril results both from an inhibitory action on the reninangiotensin system and a stimulating action on the kallikrein-kinin system The latter mechanism has been demonstrated by showing that a bradyki ...
File
... Liquid chromatography-tandem mass spectrometry was performed with Waters Acquity UPLC system interfaced to an Applied Biosystems Sciex 4000-QTRAP mass spectrometer (Applied Biosystems, Foster City, CA, USA). Analyst software (Version 1.42) was used for data acquisition and processing. Separations we ...
... Liquid chromatography-tandem mass spectrometry was performed with Waters Acquity UPLC system interfaced to an Applied Biosystems Sciex 4000-QTRAP mass spectrometer (Applied Biosystems, Foster City, CA, USA). Analyst software (Version 1.42) was used for data acquisition and processing. Separations we ...
The Risk of Myocardial Infarction Associated With Antihypertensive
... härm, especially for the short-acting dihydropyridine class.121 1('17 In one recent meta-analysis,1 '· mortality was significantly increased, and there was a strong linear relationship between the dose of nifedipine and the risk of mortality (P=.01). Whether similar adverse effects appear among pati ...
... härm, especially for the short-acting dihydropyridine class.121 1('17 In one recent meta-analysis,1 '· mortality was significantly increased, and there was a strong linear relationship between the dose of nifedipine and the risk of mortality (P=.01). Whether similar adverse effects appear among pati ...
ANTIHYPERTENSIVE DRUG THERAPY FOR HYPERTENSIVE DISORDERS IN PREGNANCY Review article
... appear, discontinuation of usage because of adverse effects is uncommon (17). Although atenolol is commonly used cardioselective β blocker in non-pregnancy, it has been considered that in pregnancy, especially in early pregnancy, usage of atenolol should be avoided. Based upon results of placebo-con ...
... appear, discontinuation of usage because of adverse effects is uncommon (17). Although atenolol is commonly used cardioselective β blocker in non-pregnancy, it has been considered that in pregnancy, especially in early pregnancy, usage of atenolol should be avoided. Based upon results of placebo-con ...
Selexipag for the treatment of pulmonary arterial hypertension
... to a long-acting metabolite that binds with high selectivity to IP receptors, resulting in vasodilation, inhibition of platelet aggregation, and antiinflammatory effects. Results of a long-term, placebo-controlled, clinical outcomes–driven trial showed that selexipag significantly reduced the occurr ...
... to a long-acting metabolite that binds with high selectivity to IP receptors, resulting in vasodilation, inhibition of platelet aggregation, and antiinflammatory effects. Results of a long-term, placebo-controlled, clinical outcomes–driven trial showed that selexipag significantly reduced the occurr ...
S 06 Adrenoceptor Agonists And Sympathomimetic Drugs
... β1 receptors: direct effects on the heart are determined largely by β1 receptors. Both the heart rate (chronotropic effect) and the force of contraction (inotropic effect) are increased, resulting in a markedly increased cardiac output and cardiac oxygen consumption ...
... β1 receptors: direct effects on the heart are determined largely by β1 receptors. Both the heart rate (chronotropic effect) and the force of contraction (inotropic effect) are increased, resulting in a markedly increased cardiac output and cardiac oxygen consumption ...
351 Pharmacology PNS 5th Lecture F
... is readily absorbed, form the basis for the use of nicotine as an insecticide. These drugs are not used clinically, but only as experimental tools. They cause complex peripheral responses associated with generalized stimulation of ALL autonomic ganglia (sympathetic & parasympathetic) ...
... is readily absorbed, form the basis for the use of nicotine as an insecticide. These drugs are not used clinically, but only as experimental tools. They cause complex peripheral responses associated with generalized stimulation of ALL autonomic ganglia (sympathetic & parasympathetic) ...