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Immunoglobulins structure and function
Immunoglobulins structure and function

... EFFECTOR FUNCTIONS OF ANTIBODIES Antibody-mediated immune responses ...
Document
Document

... = 320 different light chains If H and L chains pair randomly as H2L2 i.e. 6,480 x 320 = 2,073,600 possibilities Due only to COMBINATORIAL diversity In practice, some H + L combinations do not occur as they are unstable Certain V and J genes are also used more frequently than others. There are other ...
5 Immunoglobulins
5 Immunoglobulins

... EFFECTOR FUNCTIONS OF ANTIBODIES Antibody-mediated immune responses ...
MCB 181 (Nov 4 – Dec 4) Information and Heredity
MCB 181 (Nov 4 – Dec 4) Information and Heredity

... lymphocytes and antibodies of the immune system. • There are two main types of lymphocytes: B lymphocytes (B cells) and T lymphocytes (T cells) • Both are types of white blood cells produced in bone marrow. They circulate in blood and lymph, and are concentrated in spleen, lymph nodes, and other lym ...
Severe combined immune deficiency syndrome
Severe combined immune deficiency syndrome

... 8. Infections that do not resolve with antibiotic treatment for two or more months 9. Failure to gain weight or grow normally 10. Infections that require intravenous antibiotic treatment 11. Deep-seated infections, such as pneumonia that affects an entire lung or an abscess in the liver 12. Persiste ...
Chapter 14 Forensic Serology CHAPTER OVERVIEW • Serology
Chapter 14 Forensic Serology CHAPTER OVERVIEW • Serology

... Serology involves a broad scope of laboratory tests that use specific antigen and serum antibody reactions. ...
Rh NEGATIVE PREGNANCY
Rh NEGATIVE PREGNANCY

... to an antigen derived from another individual of the same species provided first one lacks the antigen. This occurs in two stages Sensitisation Immunisation In ABO - blood groups naturally occurring anti-A, anti-B antibodies are present in the serum. But in Rh group there is no such naturally occurr ...
Antibodies and Antigens
Antibodies and Antigens

... Figure 16.4 Antibody structure ...
Immunology
Immunology

... ◦ Antigens-a marker on the surface of cell that identifies it as “self” or “non-self” ◦ Antibody-a substance produced by B lymphocytes in response to the presence of a foreign antigen that will combine with and control the antigen, thus preventing infection ◦ Immunity-a long term condition of protec ...
23. Frenkel lecture: FMD vaccine development - past and future
23. Frenkel lecture: FMD vaccine development - past and future

... virus with cattle dendritic cells (DC). Development of a comprehensive protective T and B cell response requires antigen capture, migration, maturation and antigen presentation by DCs. The capacity to stimulate CD8 and CD4 T cells relies upon the presentation of antigen through MHC class I and II mo ...
Presentation slides - Yale School of Medicine
Presentation slides - Yale School of Medicine

... • most efficient of all APCs • high MHC class I, II & costimulators • efficient cross presentation • stimulate naïve T cells (CD4, CD8) initiate Ag-specific immune responses ...
OTHER DISEASE CAUSING FACTORS
OTHER DISEASE CAUSING FACTORS

... to offspring • Non-communicable diseases – Cannot be passed from one person to another through contact or proximity – Ex: • Diabetes, hypertension, cystic fibrosis, PKU, hemophilia, sickle cell, red green color blindness, etc ...
RESPON IMUN TERHADAP INFEKSI
RESPON IMUN TERHADAP INFEKSI

... Each produces a different receptor in the cell membrane Each receptor is composed of 1 molecule each of two different proteins Each receptor binds a specific antigen but has only one binding site Receptor only recognizes antigens which are "presented" to it within another membrane protein of the MHC ...
Adaptive Immune Response (Part II) (Antibody
Adaptive Immune Response (Part II) (Antibody

... Clonal Selection of B Cells is Caused by Clonal selection and clonal proliferation. Antigenic Stimulation ...
Basics of Immunology
Basics of Immunology

... Microorganisms will invariably be found in microbiology laboratories. The greatest risk of occupational infection in these laboratories is associated with the use of pathogenic microorganisms or the handling of contaminated material. Safety begins with the collection of the specimen. The approach ...
Arg89Cys Substitution Results in Very Low
Arg89Cys Substitution Results in Very Low

... clinical medicine because of their involvement in transfusion incompatibilities and hemolityc disease of the newborn (HDN).1 The Duffy blood group system should represent one of the best illustrations of the link between genetics and biology. Indeed, before their molecular cloning, the Duffy antigen ...
Immune Responses
Immune Responses

... 3) tissue repair G) Fever 1) caused by pyrogens a) any chemical that causes an increase in body temperature b) most often released from WBC, as well as some bacteria 2) promote sequestration of iron & zinc 3) may aid interferon, inhibit microbe growth, & speed reaction time of defense cells H) Compl ...
A1988Q298300001
A1988Q298300001

... persons with acute or chronic1~2carrier type infections with this virus. At the time this study was done, we called this the serum hepatitis-related antigen (SH), while B.S. Blumberg and3his group called it the Australia antigen. It thus became possible to systematically study the geographic distrib ...
Immunity revision sheets
Immunity revision sheets

... Antibodies meet with an antigen and bind with it. Give three ways that the antibody can deal with the antigen. ...
Antigens and Antigen Receptors (lecture notes pages 19-24)
Antigens and Antigen Receptors (lecture notes pages 19-24)

... See animation of rearrangement 4. Recombination Inaccuracies See Animation 5. Somatic mutations ...
IMMUNOLOGY (Ms. Lucky Juneja)
IMMUNOLOGY (Ms. Lucky Juneja)

... of specificity, diversity, memory, and self/nonself recognition.  B-Lymphocytes (B-cells), T- Lymphocytes (T-cells). ...
Lecture 4 Antigen Recognition
Lecture 4 Antigen Recognition

... Pre-existence of of many different potential antibody producing cells Each cell displays surface receptors for specific antigens Antigen encounter selects cells ...
Chapter 17 Immune Response
Chapter 17 Immune Response

... • T cells do not respond to antigens floating around in the body fluids. • They respond to intracellular antigens. • Antigen has to be processed and presented to the T cells by an antigen presenting cell – macrophage. ...
File - Classes with Mrs. Sheetz
File - Classes with Mrs. Sheetz

... prevent future infection ...
Immunology
Immunology

...  Gamma interferon - produced by lymphocytes, mobilizes and activates macrophages and NK cells, stimulates synthesis and expression of more class I and II MHC, and enhances activity of B cells and cytotoxic T cells  Alpha interferon - produced by most leukocytes, mobilizes and activates macrophages ...
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Duffy antigen system

Duffy antigen/chemokine receptor (DARC) also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234) is a protein that in humans is encoded by the DARC gene.The Duffy antigen is located on the surface of red blood cells, and is named after the patient in which it was discovered. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The protein is also the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system.
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