Slide 1
... Hepatic damage predominantly immune mediated - cytotoxic T cells HBV specific peptides presented on the infected liver cell surface recognized by Ag specific CD8 T cells hepatocellular inflammation and necrosis. AWACC 2009 ...
... Hepatic damage predominantly immune mediated - cytotoxic T cells HBV specific peptides presented on the infected liver cell surface recognized by Ag specific CD8 T cells hepatocellular inflammation and necrosis. AWACC 2009 ...
Diseases Caused by Systemic Prokaryotic Organisms
... (C. jambhiri), kumquats (Fortunella spp.) and citrons (C. medica). Symptoms are even weaker on limes (C. aurantiifolia) and pummelos (C. grandis). Though other Rutaceae have been infected artificially, there are not apparently any records of their natural infection. Citrus greening bacterium c ...
... (C. jambhiri), kumquats (Fortunella spp.) and citrons (C. medica). Symptoms are even weaker on limes (C. aurantiifolia) and pummelos (C. grandis). Though other Rutaceae have been infected artificially, there are not apparently any records of their natural infection. Citrus greening bacterium c ...
Autoimmune Disease is Causing Your Hashimoto Thyroiditis And How to Stop It!
... of days. I had to finally admit that I was no longer able to continue strenuous physical activities. And I was gaining weight. The pounds were piling on. My once trim body was outgrowing all my clothes. I cried the day I had to wear double digits. I went crawling back to doctors for help. More tests ...
... of days. I had to finally admit that I was no longer able to continue strenuous physical activities. And I was gaining weight. The pounds were piling on. My once trim body was outgrowing all my clothes. I cried the day I had to wear double digits. I went crawling back to doctors for help. More tests ...
- Circle of Docs
... 1. Increased ADI = congeneital or acquired causes a. Down syndrome patients may have missing transverse ligament b. Take flexion and extension x-rays for stability before adjusting or letting child compete in special olympics (?) Acquired: 1. RA 2. Trauma 3. AS 4. Psoriatic - PA 5. Reiters syndrome ...
... 1. Increased ADI = congeneital or acquired causes a. Down syndrome patients may have missing transverse ligament b. Take flexion and extension x-rays for stability before adjusting or letting child compete in special olympics (?) Acquired: 1. RA 2. Trauma 3. AS 4. Psoriatic - PA 5. Reiters syndrome ...
Physics - BC Open Textbooks
... After initially binding an antigen to the B cell receptor, a B cell internalizes the antigen and presents it on MHC class II. A helper T cell recognizes the MHC class II-antigen complex and activates the B cell. As a result, memory B cells and plasma cells are made. ...
... After initially binding an antigen to the B cell receptor, a B cell internalizes the antigen and presents it on MHC class II. A helper T cell recognizes the MHC class II-antigen complex and activates the B cell. As a result, memory B cells and plasma cells are made. ...
HPI
... • > 10 mmHg fall in systolic blood pressure during inspiration • Seen with cardiac tamponade, asthma, pericarditis ...
... • > 10 mmHg fall in systolic blood pressure during inspiration • Seen with cardiac tamponade, asthma, pericarditis ...
cholangitis/cholangiohepatitis syndrome
... (lymphoplasmacytic, lymphocytic), “granulomatous,” or “lymphoproliferative” (transition to lymphoma) based on microscopic examination of biopsy samples “Suppurative” refers to the presence of pus in the affected tissue; “nonsuppurative” refers to an inflammatory process that is not characterized b ...
... (lymphoplasmacytic, lymphocytic), “granulomatous,” or “lymphoproliferative” (transition to lymphoma) based on microscopic examination of biopsy samples “Suppurative” refers to the presence of pus in the affected tissue; “nonsuppurative” refers to an inflammatory process that is not characterized b ...
Cholangitis/ Cholangiohepatitis Syndrome
... (lymphoplasmacytic, lymphocytic), “granulomatous,” or “lymphoproliferative” (transition to lymphoma) based on microscopic examination of biopsy samples “Suppurative” refers to the presence of pus in the affected tissue; “nonsuppurative” refers to an inflammatory process that is not characterized b ...
... (lymphoplasmacytic, lymphocytic), “granulomatous,” or “lymphoproliferative” (transition to lymphoma) based on microscopic examination of biopsy samples “Suppurative” refers to the presence of pus in the affected tissue; “nonsuppurative” refers to an inflammatory process that is not characterized b ...
Peripheral Neuropathy - American Academy of Neurology
... body parts might also be affected. Most people who develop peripheral neuropathy are over age 55. But people can be affected at any age. ...
... body parts might also be affected. Most people who develop peripheral neuropathy are over age 55. But people can be affected at any age. ...
Elimination
... ability to void are Antecedents for the Elimination Concept. These entities/processes must be in place before normal elimination can result. Normal Elimination is defined as the formation, passage and excretion of waste products. The concept of Elimination is optimally operationalized when there is ...
... ability to void are Antecedents for the Elimination Concept. These entities/processes must be in place before normal elimination can result. Normal Elimination is defined as the formation, passage and excretion of waste products. The concept of Elimination is optimally operationalized when there is ...
Rh-Mediated Isoimmune Hemolytic Disease
... Reticulocyte count: 23% Unconjugated bilirubin: 9.1 Conjugated bilirubin: 0.1 Blood type: A+ (antibody +) Maternal blood type: A- (antibody + x2) 16 hours of age: Unconjugated bilirubin:18.8 ...
... Reticulocyte count: 23% Unconjugated bilirubin: 9.1 Conjugated bilirubin: 0.1 Blood type: A+ (antibody +) Maternal blood type: A- (antibody + x2) 16 hours of age: Unconjugated bilirubin:18.8 ...
Clinical Case Conference
... intravenously for three to five days Can be used as intensification of maintenance immunosuppression therapy Usually the only additional treatment added if the rejection is Banff class 1A or 1B Complications: Increased susceptibility to infection, especially oral candidiasis. Other issues incl ...
... intravenously for three to five days Can be used as intensification of maintenance immunosuppression therapy Usually the only additional treatment added if the rejection is Banff class 1A or 1B Complications: Increased susceptibility to infection, especially oral candidiasis. Other issues incl ...
The danger model in deciphering autoimmunity
... makes it hard to infer what the origin of autoimmunity is, and the resulting inflammatory response against exposed antigenic structures makes it difficult to separate primary and secondary events. ...
... makes it hard to infer what the origin of autoimmunity is, and the resulting inflammatory response against exposed antigenic structures makes it difficult to separate primary and secondary events. ...
Predominant cellular immune response to the cartilage
... The spondyloarthropathies are frequently occurring inflammatory rheumatic diseases w1x, in part leading to significant burden of disease with pain and disability probably not so much different from rheumatoid arthritis (RA) w2x. Ankylosing spondylitis (AS) and undifferentiated spondylarthropathies a ...
... The spondyloarthropathies are frequently occurring inflammatory rheumatic diseases w1x, in part leading to significant burden of disease with pain and disability probably not so much different from rheumatoid arthritis (RA) w2x. Ankylosing spondylitis (AS) and undifferentiated spondylarthropathies a ...
Calcium Pyrophosphate Dihydrate Crystal Deposition Disease (Pseudogout) of Lumbar Spine Mimicking Osteomyelitis-
... citis, and a fluoroscopy-guided percutaneous biopsy was performed. The patient did not receive antibiotics. Final cultures were negative and pathology was nondiagnostic. Treatment with an epidural steroid injection resolved the pain. The patient returned 2 months later with worsening bilateral leg p ...
... citis, and a fluoroscopy-guided percutaneous biopsy was performed. The patient did not receive antibiotics. Final cultures were negative and pathology was nondiagnostic. Treatment with an epidural steroid injection resolved the pain. The patient returned 2 months later with worsening bilateral leg p ...
Part 4 questions 2
... Atlas anterior means: 1. Increased ADI = congeneital or acquired causes a. Down syndrome patients may have missing transverse ligament b. Take flexion and extension x-rays for stability before adjusting or letting child compete in special olympics (?) Acquired: 1. RA 2. Trauma 3. AS 4. Psoriatic - P ...
... Atlas anterior means: 1. Increased ADI = congeneital or acquired causes a. Down syndrome patients may have missing transverse ligament b. Take flexion and extension x-rays for stability before adjusting or letting child compete in special olympics (?) Acquired: 1. RA 2. Trauma 3. AS 4. Psoriatic - P ...
Is It A Cold, Allergy or Both?
... temperature and humidity are fairly constant throughout the year, symptoms may be present all year even from pollens. Because the IgE antibodies that are made by the white blood cells of a person suffering from allergies not only stay in the tissues where the allergens come into contact with the bo ...
... temperature and humidity are fairly constant throughout the year, symptoms may be present all year even from pollens. Because the IgE antibodies that are made by the white blood cells of a person suffering from allergies not only stay in the tissues where the allergens come into contact with the bo ...
Stress and autoimmunity
... “general adaptation syndrome” (GAS). Philosophically, the concept of adaptation runs through most life activities, from wound response, to language, to literature and beyond. The general adaptation syndrome is one which invokes a systemic response (Fig. 1). The initial inspiration for GAS came from ...
... “general adaptation syndrome” (GAS). Philosophically, the concept of adaptation runs through most life activities, from wound response, to language, to literature and beyond. The general adaptation syndrome is one which invokes a systemic response (Fig. 1). The initial inspiration for GAS came from ...
precious enzymes
... removal and thus less new tissue formation. This leads to less and less function as we age. In the case of muscle and bone we get stiffer and stiffer with more aches and pains. Since the body has a limited supply after the age of 27-33 years of age it will use these enzymes for the more important ar ...
... removal and thus less new tissue formation. This leads to less and less function as we age. In the case of muscle and bone we get stiffer and stiffer with more aches and pains. Since the body has a limited supply after the age of 27-33 years of age it will use these enzymes for the more important ar ...
Alessio Fasano, MD Visiting Professor of Pediatrics Harvard Medical
... predisposed individuals. • Causes an inflammatory damage of the mucosa of the small intestine resulting in a variety of clinical presentations. • Left untreated may lead to complications and increased mortality. © 2013 NASPGHAN FOUNDATION ...
... predisposed individuals. • Causes an inflammatory damage of the mucosa of the small intestine resulting in a variety of clinical presentations. • Left untreated may lead to complications and increased mortality. © 2013 NASPGHAN FOUNDATION ...
The role of autoantibodies in health and disease
... seems to modulate the severity or even prevent the onset of autoimmune disease [31, 34]. Knowledge on protective autoantibodies allows their use for therapeutic purposes. The protective autoantibodies may be utilized for the treatment of autoimmune diseases: e.g., IgM anti-ds DNA might serve as usef ...
... seems to modulate the severity or even prevent the onset of autoimmune disease [31, 34]. Knowledge on protective autoantibodies allows their use for therapeutic purposes. The protective autoantibodies may be utilized for the treatment of autoimmune diseases: e.g., IgM anti-ds DNA might serve as usef ...
Lung inflammatory responses
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
... adhesion, chemotaxis, and activation of leukocyte populations. While some chemokines are constitutively expressed, others are either up or downregulated in association with inflammation. Those chemokines active in inflammation are typically produced in response to infection by pathogenic microbes or ...
Meningococcal disease, the facts
... because of damage to various areas of the brain, including the nerves responsible for hearing and sight. The serious and disabling after-effects are well recognised and include hearing loss or deafness, loss of vision or blindness, epilepsy, severe brain damage, speech problems. After-effects and co ...
... because of damage to various areas of the brain, including the nerves responsible for hearing and sight. The serious and disabling after-effects are well recognised and include hearing loss or deafness, loss of vision or blindness, epilepsy, severe brain damage, speech problems. After-effects and co ...
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly the wrist and hands are involved with typically the same joints involved on both sides of the body. The disease may also affect other parts of the body. This may result in low red blood cells, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often symptoms come on gradually over weeks to months.While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.The goal of treatment is to improve pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs) may be used to try to slow the progression of disease. They include the medications hydroxychloroquine and methotrexate. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fusion joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013 it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints.