Document
... What is the minimum dose of thiopurines or methotrexate needed to augment effectiveness of ...
... What is the minimum dose of thiopurines or methotrexate needed to augment effectiveness of ...
Immunopathogenesis of chronic periapical
... organism into the root canalsof cats. The root canal as a pathway for introducing antigens was used by Barnes and Langeland.34They depositedbovine serum albumin into the pulp spacesof monkey teeth and observed the formation of systemic antibodies. Further evidence of the feasibility of the root cana ...
... organism into the root canalsof cats. The root canal as a pathway for introducing antigens was used by Barnes and Langeland.34They depositedbovine serum albumin into the pulp spacesof monkey teeth and observed the formation of systemic antibodies. Further evidence of the feasibility of the root cana ...
Pelvic Pain – Dysmenorrhea and Endometriosis
... • Approximately 15-20% of women aged 18-50 years have CPP of greater than 1 year’s duration • 20-50% of women who receive care in primary care practices have > 1 diagnosis • Demographic profiles suggest no difference in woman w/ CPP compared to women w/o CPP in terms of age, race and ethnicity, educ ...
... • Approximately 15-20% of women aged 18-50 years have CPP of greater than 1 year’s duration • 20-50% of women who receive care in primary care practices have > 1 diagnosis • Demographic profiles suggest no difference in woman w/ CPP compared to women w/o CPP in terms of age, race and ethnicity, educ ...
Peer-reviewed Article PDF - e
... The study findings suggested that male major depression patients with early life stress may clinically exhibit stress induced increases in inflammatory markers that are further exacerbated by exposure to acute stress. These findings indicate that depressed patients with increased early life stress e ...
... The study findings suggested that male major depression patients with early life stress may clinically exhibit stress induced increases in inflammatory markers that are further exacerbated by exposure to acute stress. These findings indicate that depressed patients with increased early life stress e ...
Current and novel therapeutics in the treatment of systemic lupus erythematosus
... the US Food and Drug Administration (FDA) for the treatment of relapsed or refractory B-cell lymphoma in 1997.12 There are data on the efficacy of rituximab in a variety of other autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, type I diabetes, anti-neutrophil cytoplasmi ...
... the US Food and Drug Administration (FDA) for the treatment of relapsed or refractory B-cell lymphoma in 1997.12 There are data on the efficacy of rituximab in a variety of other autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, type I diabetes, anti-neutrophil cytoplasmi ...
Histopathology of bronchiectasis
... be confined to a single lobe. However, nonobstructive bronchiectasis may occur in association with a number of other conditions. In diseases where mucociliary clearance is impaired, bronchiectasis frequently, if not inevitably, develops. In cystic fibrosis [14] and ciliary dysmotility syndromes, suc ...
... be confined to a single lobe. However, nonobstructive bronchiectasis may occur in association with a number of other conditions. In diseases where mucociliary clearance is impaired, bronchiectasis frequently, if not inevitably, develops. In cystic fibrosis [14] and ciliary dysmotility syndromes, suc ...
Superantigens and Their Role in Autoimmune Disorders
... More recently attention has focused on the ability of bacteria and viruses to contribute to the autoimmune process through their ability to produce proteins termed “superantigens”. The term “superantigen” was first used by MARRACK and KAPPLER32 to describe the ability of these agents to activate lar ...
... More recently attention has focused on the ability of bacteria and viruses to contribute to the autoimmune process through their ability to produce proteins termed “superantigens”. The term “superantigen” was first used by MARRACK and KAPPLER32 to describe the ability of these agents to activate lar ...
Bacterial components plus vitamin D: The ultimate solution to the
... similar results to those studies cited above. We found that IL-10, an anti-inflammatory, Treg controlling cytokine modulated in part by vitamin D, was increased in the cord blood of children whose mothers had a higher number of anaerobes in their gut. We went on to show that greater diversity of the ...
... similar results to those studies cited above. We found that IL-10, an anti-inflammatory, Treg controlling cytokine modulated in part by vitamin D, was increased in the cord blood of children whose mothers had a higher number of anaerobes in their gut. We went on to show that greater diversity of the ...
Host responses in periodontal diseases: a preview
... information on host responses in periodontitis. A vast amount of knowledge provided by research experts has been gathered in a format that we hope is clear and illustrative for the readers. In order to investigate the pathogenesis of periodontitis, it is essential to understand how the immune system ...
... information on host responses in periodontitis. A vast amount of knowledge provided by research experts has been gathered in a format that we hope is clear and illustrative for the readers. In order to investigate the pathogenesis of periodontitis, it is essential to understand how the immune system ...
Vasculitis: Attack of the Leukocytes
... • Peripheral nerves: Peripheral nerve symptoms may include numbness and tingling (usually in an arm or a leg, or in areas which would be covered by gloves or socks), loss of sensation, or loss of strength (especially in the feet or hands). • Intestines: Inadequate blood flow in the intestines can ca ...
... • Peripheral nerves: Peripheral nerve symptoms may include numbness and tingling (usually in an arm or a leg, or in areas which would be covered by gloves or socks), loss of sensation, or loss of strength (especially in the feet or hands). • Intestines: Inadequate blood flow in the intestines can ca ...
Immune modulation of some autoimmune diseases: the critical role
... cytokines depending on the microenvironment, acting with different physiological functions [31]. Recently, macrophages are subdivided in two main phenotypes: the classically activated macrophages (M1 macrophages) promote tissue inflammation and activated macrophages (M2 macrophages), these last is c ...
... cytokines depending on the microenvironment, acting with different physiological functions [31]. Recently, macrophages are subdivided in two main phenotypes: the classically activated macrophages (M1 macrophages) promote tissue inflammation and activated macrophages (M2 macrophages), these last is c ...
New insights into the link between cardiovascular disease and
... CVD as a risk factor for depression. The third model proposes a common underlying pathway related to the effects of chronic stress on the body in manifesting as depression or cardiovascular disease. Conclusions: If the proposed model holds true, it may be possible that an intervention initiated befo ...
... CVD as a risk factor for depression. The third model proposes a common underlying pathway related to the effects of chronic stress on the body in manifesting as depression or cardiovascular disease. Conclusions: If the proposed model holds true, it may be possible that an intervention initiated befo ...
Psoas abscess with septic arthritis of the hip: a case report
... hip, it is usually impossible to move the limb passively without pain, regardless of the limb’s position. However, this sign is suspicious in such young children, who are irritable and apprehensive during the examination 2,4. Our patient was admitted with the complaints of fever, pain and limping si ...
... hip, it is usually impossible to move the limb passively without pain, regardless of the limb’s position. However, this sign is suspicious in such young children, who are irritable and apprehensive during the examination 2,4. Our patient was admitted with the complaints of fever, pain and limping si ...
2,6-sialylated Fc
... It contains the pooled IgG extracted from the plasma of over one thousand blood donors Immunoglobulin products from human plasma were first used in 1952 to treat immune ...
... It contains the pooled IgG extracted from the plasma of over one thousand blood donors Immunoglobulin products from human plasma were first used in 1952 to treat immune ...
The Combined Benefit of Negative Pressure Therapy (N.P.T.
... chronic steroid use, vascular disease, and MRSA colonization deter wound healing and encourage resistance to typically reliable wound healing techniques. These hard to heal wounds invite further complications including infection, pain, disability, and amputation. Often these patients are not candida ...
... chronic steroid use, vascular disease, and MRSA colonization deter wound healing and encourage resistance to typically reliable wound healing techniques. These hard to heal wounds invite further complications including infection, pain, disability, and amputation. Often these patients are not candida ...
UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis
... We have previously shown that similar doses of UVR have not significantly altered 25(OH)D levels in vitamin D-replete mice [28]. In our previous studies, neither acute erythemal (8 kJ/m2) or chronic suberythemal (8 exposures of 2 kJ/m2) UVR significantly altered 25(OH) D levels. Furthermore, Becklun ...
... We have previously shown that similar doses of UVR have not significantly altered 25(OH)D levels in vitamin D-replete mice [28]. In our previous studies, neither acute erythemal (8 kJ/m2) or chronic suberythemal (8 exposures of 2 kJ/m2) UVR significantly altered 25(OH) D levels. Furthermore, Becklun ...
Psoriasis: More Than Cosmetic
... "We also try to choose a drug with an appropriate benefit-risk ratio," she says. For mild psoriasis, a topical steroid may be appropriate. For more severe disease, where it becomes impractical to apply topicals over a large surface area several times a day, a patient may need a systemic treatment. M ...
... "We also try to choose a drug with an appropriate benefit-risk ratio," she says. For mild psoriasis, a topical steroid may be appropriate. For more severe disease, where it becomes impractical to apply topicals over a large surface area several times a day, a patient may need a systemic treatment. M ...
Rose Disorder: Rust - The Learning Store
... spores. These spores may be scraped off the leaf surface with a knife. Examine lower leaves first, looking at both sides of the leaves. The effects of this disease may be mild or severe depending on the season and how early the plants become infected. Another form of rust affects Rosa foetida and so ...
... spores. These spores may be scraped off the leaf surface with a knife. Examine lower leaves first, looking at both sides of the leaves. The effects of this disease may be mild or severe depending on the season and how early the plants become infected. Another form of rust affects Rosa foetida and so ...
If You Google Auto-Immune Disease, You`ll Find
... that the immune system is in. It is NOT a disease of an organ; and even though it is given a multitude of names depending on the tissue currently affected, it is a STATE of the immune system attacking the tissue it was meant to protect. We also know that when people have low thyroid activity, Insuli ...
... that the immune system is in. It is NOT a disease of an organ; and even though it is given a multitude of names depending on the tissue currently affected, it is a STATE of the immune system attacking the tissue it was meant to protect. We also know that when people have low thyroid activity, Insuli ...
psoriasis
... Can be used alone or combined with oral medications or light therapy. Topical psoriasis treatments include: Topical corticosteroids. The most frequently prescribed medications for treating mild to moderate psoriasis. They slow cell turnover by suppressing the immune system, which reduces inflammatio ...
... Can be used alone or combined with oral medications or light therapy. Topical psoriasis treatments include: Topical corticosteroids. The most frequently prescribed medications for treating mild to moderate psoriasis. They slow cell turnover by suppressing the immune system, which reduces inflammatio ...
Primary Immunodeficiency and Autoimmunity: Lessons From Human
... immune system and are often associated with autoimmune diseases. We describe PID affecting T-regulatory cells, complement and B cells or their products and discuss the possibility of a cause–effect relationship. The high concordance of T-regulatory cell defects to organ-specific autoimmune disease i ...
... immune system and are often associated with autoimmune diseases. We describe PID affecting T-regulatory cells, complement and B cells or their products and discuss the possibility of a cause–effect relationship. The high concordance of T-regulatory cell defects to organ-specific autoimmune disease i ...
psoriasis associated with chronic periodontitis: a rare
... response (T- and B-cell response) is important in the pathogenesis of both psoriasis and periodontitis.11,12 Both psoriasis and periodontal diseases are characterized by an exaggerated immune response to the microbiota residing on epithelial surfaces. Dendritic cells (DCs) play an important role in ...
... response (T- and B-cell response) is important in the pathogenesis of both psoriasis and periodontitis.11,12 Both psoriasis and periodontal diseases are characterized by an exaggerated immune response to the microbiota residing on epithelial surfaces. Dendritic cells (DCs) play an important role in ...
Chronic Neutropenia Associated With Autoimmune Disease
... Felty’s syndrome are HLA-DR4 –positive, similar to LGL leukemia and RA. In contrast, patients with LGL leukemia not associated with RA have a normal prevalence of HLA-DR4.6,51 These immunogenetic findings support the concept that Felty’s syndrome and LGL leukemia with RA are part of a single disease ...
... Felty’s syndrome are HLA-DR4 –positive, similar to LGL leukemia and RA. In contrast, patients with LGL leukemia not associated with RA have a normal prevalence of HLA-DR4.6,51 These immunogenetic findings support the concept that Felty’s syndrome and LGL leukemia with RA are part of a single disease ...
meniscus tear - The Children`s Hospital at Montefiore
... For jumping sports (basketball, volleyball) or contact sports, protect vulnerable joints with supportive devices, such as wrapped elastic bandages, tape, or braces (these have not been proven effective). Wear proper protective equipment and ensure correct fit, including proper cleats for the surface ...
... For jumping sports (basketball, volleyball) or contact sports, protect vulnerable joints with supportive devices, such as wrapped elastic bandages, tape, or braces (these have not been proven effective). Wear proper protective equipment and ensure correct fit, including proper cleats for the surface ...
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly the wrist and hands are involved with typically the same joints involved on both sides of the body. The disease may also affect other parts of the body. This may result in low red blood cells, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often symptoms come on gradually over weeks to months.While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.The goal of treatment is to improve pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs) may be used to try to slow the progression of disease. They include the medications hydroxychloroquine and methotrexate. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fusion joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013 it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints.