
Electron Transport Chain _ETC
... Energy-rich molecules, such as glucose, are metabolized by a series of oxidation reactions ultimately yielding Co2 and water. The metabolic intermediates of these reactions donate electrons to specific coenzymes ( NAD+,FAD) and The reduced form of these coenzymes ( NADH,FADH2) can, in turn, each don ...
... Energy-rich molecules, such as glucose, are metabolized by a series of oxidation reactions ultimately yielding Co2 and water. The metabolic intermediates of these reactions donate electrons to specific coenzymes ( NAD+,FAD) and The reduced form of these coenzymes ( NADH,FADH2) can, in turn, each don ...
Neuron Structure and Function
... pumps 2 Ca2+ ions out for every 1 ATP molecule used Uses ATP to drive Ca 2+ out against a very large concentration gradient Internal Ca 2+ binding sites have a very high affinity (in order to overcome extremely low Ca2+ concentrations inside cell) Energy transfer from ATP to the aspartate of the ...
... pumps 2 Ca2+ ions out for every 1 ATP molecule used Uses ATP to drive Ca 2+ out against a very large concentration gradient Internal Ca 2+ binding sites have a very high affinity (in order to overcome extremely low Ca2+ concentrations inside cell) Energy transfer from ATP to the aspartate of the ...
slides - IUN.edu
... If the plasma membrane of animal cells was made permeable to Na+ and K+, the Na+K+ pump would: A. be completely inhibited. B. begin to pump Na+ in both directions. C. begin synthesizing ATP instead of hydrolyzing it. D. continue to pump ions and to hydrolyze ATP but the energy of hydrolysis would b ...
... If the plasma membrane of animal cells was made permeable to Na+ and K+, the Na+K+ pump would: A. be completely inhibited. B. begin to pump Na+ in both directions. C. begin synthesizing ATP instead of hydrolyzing it. D. continue to pump ions and to hydrolyze ATP but the energy of hydrolysis would b ...
Initiation at Class I Promoters
... DNA-binding domains 1. Zinc–containing motifs – Zinc fingers (Sp1 and TFIIIA) – Zinc modules (GR and other nuclear ...
... DNA-binding domains 1. Zinc–containing motifs – Zinc fingers (Sp1 and TFIIIA) – Zinc modules (GR and other nuclear ...
survey of biochemistry - School of Chemistry and Biochemistry
... • Hydrolases break down chemicals through the use of water. ...
... • Hydrolases break down chemicals through the use of water. ...
Chapter 14-Respiration
... (inside inner membrane) and transported into the space between the inner and outer mitochondrial membranes by Complexes I, III, IV. This electrochemical work is done using the G released during ...
... (inside inner membrane) and transported into the space between the inner and outer mitochondrial membranes by Complexes I, III, IV. This electrochemical work is done using the G released during ...
Protein Kinases Structural Features
... decrease in kcat/Km of 1000 fold The other amino acid was Asp 184 located in the C-terminal lobe. Although this paper postulates that it may be the catalytic base, Xray structures show that it is the critical residue for chelating and positioning the Mg ion in the active site. Mutation of Asp 184 re ...
... decrease in kcat/Km of 1000 fold The other amino acid was Asp 184 located in the C-terminal lobe. Although this paper postulates that it may be the catalytic base, Xray structures show that it is the critical residue for chelating and positioning the Mg ion in the active site. Mutation of Asp 184 re ...
Bovine prolactin soluble receptor ECD ECD-11
... Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine re ...
... Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine re ...
Purified Mouse Anti-ATP Synthase α — 612516
... ATP synthase is a large enzyme complex that uses an electrochemical H+ or Na+ gradient to synthesize ATP from ADP and Pi, providing the organism with the ATP needed for energy. The complex consists of two major units, F0 and F1. F0 is embedded in the inner membrane of the mitochondria and, due to it ...
... ATP synthase is a large enzyme complex that uses an electrochemical H+ or Na+ gradient to synthesize ATP from ADP and Pi, providing the organism with the ATP needed for energy. The complex consists of two major units, F0 and F1. F0 is embedded in the inner membrane of the mitochondria and, due to it ...
No Slide Title
... InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences. The aim is to provide a one-stop-shop for protein family diagnostics ...
... InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences. The aim is to provide a one-stop-shop for protein family diagnostics ...
Transport across membranes File
... molecules, although polar, are small enough to diffuse across membranes in a manner that is not entirely understood. ■ Membranes are permeable to lipids, which can pass through the nonpolar interior of the lipid bilayer. Membrane permeability of most compounds is directly proportional to their parti ...
... molecules, although polar, are small enough to diffuse across membranes in a manner that is not entirely understood. ■ Membranes are permeable to lipids, which can pass through the nonpolar interior of the lipid bilayer. Membrane permeability of most compounds is directly proportional to their parti ...
Oxidative Phosphorylation and the Chemiosmotic Theory
... ATP produced in the mitochondrial matrix by oxidative phosphorylation is exported into the cell cytoplasm by a transporter protein located in the inner membrane. The same protein continuously returns ADP to the matrix for re-phosphorylation. The total pool of ATP + ADP in each cell is small and may ...
... ATP produced in the mitochondrial matrix by oxidative phosphorylation is exported into the cell cytoplasm by a transporter protein located in the inner membrane. The same protein continuously returns ADP to the matrix for re-phosphorylation. The total pool of ATP + ADP in each cell is small and may ...
File
... Used to load sugar from photosynthesizing cells of leaves into the phloem tissue for transport around the plant Used to load inorganic ions from the soil into root hair dermal cells to be transported via the xylem around the plant for metabolism ...
... Used to load sugar from photosynthesizing cells of leaves into the phloem tissue for transport around the plant Used to load inorganic ions from the soil into root hair dermal cells to be transported via the xylem around the plant for metabolism ...
Model Description Sheet
... pathway, small RNAs derived from viruses are used by Ago-2 to slice virus mRNA, protecting the cells from infection. In the miRNA pathway, Ago-2 utilizes naturally occurring miRNA to slice cellular mRNAs to control protein production. Ago-2 works by binding small (~22 nucleotide) regulatory RNAs (si ...
... pathway, small RNAs derived from viruses are used by Ago-2 to slice virus mRNA, protecting the cells from infection. In the miRNA pathway, Ago-2 utilizes naturally occurring miRNA to slice cellular mRNAs to control protein production. Ago-2 works by binding small (~22 nucleotide) regulatory RNAs (si ...
The Four Major Methods of Producing ATP
... use to produce ATP. All life produces ATP by three basic chemical methods only: oxidative phosphorylation, photophosphorylation, and substrate-level phosphorylation (Lim, 1998, p. 149). In prokaryotes ATP is produced both in the cell wall and in the cytosol by glycolysis. In eukaryotes most ATP is p ...
... use to produce ATP. All life produces ATP by three basic chemical methods only: oxidative phosphorylation, photophosphorylation, and substrate-level phosphorylation (Lim, 1998, p. 149). In prokaryotes ATP is produced both in the cell wall and in the cytosol by glycolysis. In eukaryotes most ATP is p ...
EPIgeneousTM Binding Domain Assays
... enabling FRET to occur upon light excitation. The specific signal at 665 nm is inhibited when a specific compound prevents the reader domain protein from binding to its substrate. ...
... enabling FRET to occur upon light excitation. The specific signal at 665 nm is inhibited when a specific compound prevents the reader domain protein from binding to its substrate. ...
Course Outline - Purdue University
... “Energy Transduction in Biological Membranes” (2 credits) Fall, 2014 9:30-10:20 Tuesday and Thursday, in LILY G458 I. COURSE SUMMARY This course provides an introduction to (1) the biophysical and biochemical basis for energy transduction in biological membranes; and (2) the structure and functions ...
... “Energy Transduction in Biological Membranes” (2 credits) Fall, 2014 9:30-10:20 Tuesday and Thursday, in LILY G458 I. COURSE SUMMARY This course provides an introduction to (1) the biophysical and biochemical basis for energy transduction in biological membranes; and (2) the structure and functions ...
Power Point 1 - G. Holmes Braddock
... • A Kingdoms is large and most inclusive groups in a classification. The kingdoms are Eubacteria, Archaebacteria, Protista, Fungi, Plantae, Animalia. ...
... • A Kingdoms is large and most inclusive groups in a classification. The kingdoms are Eubacteria, Archaebacteria, Protista, Fungi, Plantae, Animalia. ...
Neuron Structure and Function - University of British Columbia
... Nernst equation Each ion has a different potential given the difference in concentration gradients. ...
... Nernst equation Each ion has a different potential given the difference in concentration gradients. ...
Publications de l`équipe
... proteins can be concentrated in endocytic vesicles by specific interactions between their cytoplasmic domains and cytosolic coat proteins. It is, however, unclear whether they can be excluded from transport vesicles and what the determinants for this sorting could be. Here, we show that in the absenc ...
... proteins can be concentrated in endocytic vesicles by specific interactions between their cytoplasmic domains and cytosolic coat proteins. It is, however, unclear whether they can be excluded from transport vesicles and what the determinants for this sorting could be. Here, we show that in the absenc ...
Look at chapter 3 chemistry worksheet
... Extremely high affinity for substrate Uptake of nutrients in really low concentration (EX. Maltose) Gram – cells: periplasmic protein and is mobile Gram + cells: membrane spanning protein and is attached ...
... Extremely high affinity for substrate Uptake of nutrients in really low concentration (EX. Maltose) Gram – cells: periplasmic protein and is mobile Gram + cells: membrane spanning protein and is attached ...
Chapter 10 - Membrane Transport This chapter describes various
... The channel must be able to discriminate between K+ and other cations such as Na+ and Li , to lower the energy barrier for passage through the membrane, and to allow a rapid flux of K+. Selectivity for K+ occurs via the selectivity filter, comprised of highly-conserved residues, where an exiting K+ ...
... The channel must be able to discriminate between K+ and other cations such as Na+ and Li , to lower the energy barrier for passage through the membrane, and to allow a rapid flux of K+. Selectivity for K+ occurs via the selectivity filter, comprised of highly-conserved residues, where an exiting K+ ...
MEMBRANE PERMEABILITY ! membranes are highly impermeable
... ! when open, forms doughnut-like pore through which solutes flow rapidly by diffusion ! always move from high c to low c (down gradient) ! transport rate # substrate concentration, not saturable ! ΔG !ve, spontaneous, no energy required ! animal cells have many ion channels; highly selective, only l ...
... ! when open, forms doughnut-like pore through which solutes flow rapidly by diffusion ! always move from high c to low c (down gradient) ! transport rate # substrate concentration, not saturable ! ΔG !ve, spontaneous, no energy required ! animal cells have many ion channels; highly selective, only l ...
Movement of both endogenous and foreign molecules across
... and found throughout biology. Recently, an x-ray crystallography based structure has been presented for P-gp. The widely anticipated structure has long been touted as the “missing piece in the puzzle” to generate a mechanistic understanding of this complex protein. Has this been achieved yet and is ...
... and found throughout biology. Recently, an x-ray crystallography based structure has been presented for P-gp. The widely anticipated structure has long been touted as the “missing piece in the puzzle” to generate a mechanistic understanding of this complex protein. Has this been achieved yet and is ...
Poster
... Cells require mitochondria to produce cellular energy, allowing work to be done. Defective mitochondrial function can impair proper cell function, even leading to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease, and neonatal lethality. The defect stems from imbalances between ...
... Cells require mitochondria to produce cellular energy, allowing work to be done. Defective mitochondrial function can impair proper cell function, even leading to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease, and neonatal lethality. The defect stems from imbalances between ...
P-type ATPase

The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and eukaryotes. They are α-helical bundle primary transporters referred to as P-type ATPases because they catalyze auto- (or self-) phosphorylation of a key conserved aspartate residue within the pump. In addition, they all appear to interconvert between at least two different conformations, denoted by E1 and E2.Most members of this transporter family are specific for the pumping of a large array of cations, however one subfamily is involved in flipping phospholipids to maintain the asymmetric nature of the biomembrane.Prominent examples of P-type ATPases are the sodium-potassium pump (Na+,K+-ATPase), the plasma membrane proton pump (H+-ATPase), the proton-potassium pump (H+,K+-ATPase), and the calcium pump (Ca2+-ATPase).