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Name
Name

... belongs to the domain a. Eukarya. c. Bacteria. b. Protista. d. Archaea. ___________ 12. Unicellular organisms sometimes found in hot springs are part of the domain a. Eubacteria. c. Protista. b. Archaea. d. Eukarya. ___________ 13. The domain Eukarya includes the kingdom(s) a. Protista, Plantae, Fun ...
Fibre types
Fibre types

... By-products are carbon dioxide and water ...
Membrane Transport - Austin Publishing Group
Membrane Transport - Austin Publishing Group

... they transport, whether they are always open or gated (open only when stimulated), and most importantly, whether a source of free energy is required for operation. ...
Homology Detection
Homology Detection

... Annotate domains in LRRK2 (Human) • Obtain sequence in FASTA1 format from the NCBI2 • Enter name of the protein (LRRK2) in Uniprot3 and see all the information one can retrieve there • Put the sequence into domain databases like SMART4 or Pfam5 and mark the identified domains in ...
Level 2 Biology (90464) 2010 Assessment Schedule
Level 2 Biology (90464) 2010 Assessment Schedule

... the rate of reaction levels off. (May use a diagram to show this). • Co-enzyme – these organic molecules alter the shape of the active site in such a way that it can effectively combine with the substrate(s). Without them the enzymes will not work, or do so at a very low rate of activity. • Enzyme – ...
Level 2 Biology (90464) 2010 Assessment Schedule
Level 2 Biology (90464) 2010 Assessment Schedule

... the rate of reaction levels off. (May use a diagram to show this). • Co-enzyme – these organic molecules alter the shape of the active site in such a way that it can effectively combine with the substrate(s). Without them the enzymes will not work, or do so at a very low rate of activity. • Enzyme – ...
AMIN domains have a predicted role in localization of diverse
AMIN domains have a predicted role in localization of diverse

... together with the available experimental data can be used to make functional predictions of uncharacterized proteins. We speculate that the role of the AMIN domain is to help localize and orient a range of transport and murein remodeling activities at key points in the periplasmic space. This specul ...
Slides
Slides

... Number of homologues within a superfamily. Observed high correlation with duplication and functional diversification. ...
Outline
Outline

... 2. Endocytosis: Movement of large particles, including large molecules or entire microorganisms, into a cell by engulfing extracellular material, as the plasma membrane forms membrane-bound sacs that enter the cytoplasm. a. Phagocytosis - “cell eating”, engulf solid materials ...
Teaching Notes
Teaching Notes

... Q2. Where are the Cys residues located? Comment about how they are contributing to the stability of the structure. A2: A single S-S bond stabilizes each of the immunoglobulin domains. In addition, there is an S-S bond between one of the helices surrounding the antigen binding cleft and the beta shee ...
Ch 3 Membrane Transports
Ch 3 Membrane Transports

... Ch 3 Membrane Transports what's so dynamic about cell membranes? living things get nutrients and energy from the envrionment this is true of the entire organism and each cell this requires transport in/out of cells; across cell membrane concepts used: things move from high to low toward equilibrium ...
Question #1 - Jordan
Question #1 - Jordan

... muscles. The myosin heads on the thick filaments "hook" onto, and pull, the thin filaments towards the center of each sarcomere. The appearance of this action is transitioned from a "relaxed" to a "fully contracted" muscle. As the thin filaments slide over the thick filaments, the I bands and H zone ...
You find a multicellular organism that is autotrophic and contains
You find a multicellular organism that is autotrophic and contains

... The eukaryotes (Protista, Fungi, Plantae, Animalia) (notice that PROtista are not PROkaryotes, they are eukaryotes ...
single molecule elasticity of dna
single molecule elasticity of dna

... strain-induced conformational transition; chain "yields" and stretches out almost 2× its native B-form contour length at relatively constant force (plateau in force region) -All of hydrogen bonding and binding between 2 strands is still in tact, tilting of base pairs, tightened helix, reduction in d ...
Serine Proteases
Serine Proteases

... Bacterial Protease: Subtilisin • Alpha/beta structure • Added to detergents in washing powder to facilitate removal of ...
A CHASE domain containing protein kinase OsCRL4
A CHASE domain containing protein kinase OsCRL4

... and that have intracellular histidine-kinase or nucleotide cyclase domain, the domain has been named the CHASE domain (cyclases/histidinekinase-associated sensory extracellular) (Alexander and Thomas, 2003). In Arabidopsis, the CHASE domain is specific for AHK2, AHK3 and CRE1/AHK4 (Alexander and Tho ...
Atomic model of human Cystic Fibrosis Transmembrane
Atomic model of human Cystic Fibrosis Transmembrane

... The modeling of the NBD1 regulatory insertion has been performed using as template the experimental 3D structure of the isolated mouse CFTR NBD1 ([2], pdb 1r0z; at left), for which only six amino acids at the centre of the loop (dotted line) are not seen and which thus directly allows to completely ...
Biological Membranes and Transport Simple diffusion
Biological Membranes and Transport Simple diffusion

... Facilitated diffusion (Passive transport) Aquaporins (AQPs) Create hydrophilic transmembrane channel for passage of water (no ions) Erythrocytes (red blood cells), proximal renal tubule cells, vacuole ...
Studies of focal adhesion assembly
Studies of focal adhesion assembly

... The ability of integrins to transmit biochemical signals and mechanical force across cell membranes depends on interactions with the actin cytoskeleton. In a high-resolution structure, we showed that the integrin β tail forms an extended β-strand that interacts with β-strands C and D of the 21st imm ...
Photosynthesis
Photosynthesis

... • That ATP and reduced NADP are required for the reduction of GP to triose phosphate • That RuBP is regenerated in the calvin cycle • That triose phosphate is converted to useful organic substances ...
No Slide Title
No Slide Title

... Facilitated diffusion (Passive transport) Aquaporins (AQPs) Create hydrophilic transmembrane channel for passage of water (no ions) Erythrocytes (red blood cells), proximal renal tubule cells, vacuole ...
Nerve activates contraction
Nerve activates contraction

... (movement), Transport (of macromolecules into and out of cells), and Chemical Work (drive endergonic reactions in anabolic pathways) Plants transform light to chemical energy; they ...
Lecture 3a - Membs and Transport
Lecture 3a - Membs and Transport

... Transported substances bind carrier proteins or pass through protein channels (e.g. glucose, amino acids, and ions) ...
Supplementary method
Supplementary method

... proteins. The peptide concentration was kept at 200 M and ATP concentration was 2 mM for Aurora specific activity assays. In microfluidic EphA3 assays, 100 ng of protein was evaluated in a kinetic experiment with 5 M EphA3 fluorescent peptide substrate (5-FAMEFPIYDFLPAKKK-CONH2). Phosphorylation w ...
05 Bioelectrical phenomena in nervous cells
05 Bioelectrical phenomena in nervous cells

... Na+ and Cl- are more concentrated outside the cell K+ and organic anions (organic acids and proteins) are more concentrated inside. ...
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P-type ATPase



The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and eukaryotes. They are α-helical bundle primary transporters referred to as P-type ATPases because they catalyze auto- (or self-) phosphorylation of a key conserved aspartate residue within the pump. In addition, they all appear to interconvert between at least two different conformations, denoted by E1 and E2.Most members of this transporter family are specific for the pumping of a large array of cations, however one subfamily is involved in flipping phospholipids to maintain the asymmetric nature of the biomembrane.Prominent examples of P-type ATPases are the sodium-potassium pump (Na+,K+-ATPase), the plasma membrane proton pump (H+-ATPase), the proton-potassium pump (H+,K+-ATPase), and the calcium pump (Ca2+-ATPase).
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