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Cancer Registry Report 2011 HRMC Cancer Registry Case Reporting
Cancer Registry Report 2011 HRMC Cancer Registry Case Reporting

Open the PPT - Prostate Awareness Foundation
Open the PPT - Prostate Awareness Foundation

...  During 23.2 years of follow-up, 200 of 347 men in the surgery group and 247 of the 348 men in the watchful-waiting group died. Of the deaths, 63 in the surgery group and 99 in the watchfulwaiting group were due to prostate cancer; the relative risk was 0.56 (95% confidence interval [CI], 0.41 to 0 ...
National Cancer Registrars Association “Elevator Speech” I am a
National Cancer Registrars Association “Elevator Speech” I am a

Right Apex: Adenocarcinoma of the prostate, Gleason grade 3+4=7
Right Apex: Adenocarcinoma of the prostate, Gleason grade 3+4=7

lung cancer is the leading cause of cancer deaths among african
lung cancer is the leading cause of cancer deaths among african

... R E S E A R C H U N DE R F U N DE D W H E N S O MA N Y P E OP L E A R E DY I N G A N D S O MA N Y QU E ST I ON S N E E D TO B E A N SW E R E D? • Why does lung cancer have such a profoundly higher impact on African American men? • Is there an increased sensitivity to tobacco smoke? ...
Document
Document

Prostate cancer * Who needs screening?
Prostate cancer * Who needs screening?

... does not identify a large proportion of men who in fact have prostate cancer. • A positive test will lead in most cases to a biopsy, which often does not give a definitive answer and leads to anxiety and to further investigations. • Current research indicates for every 100,000 men at age 50 offered ...
Cancer of Unknown Primay
Cancer of Unknown Primay

... – Patients ‘referred’ where absolutely no workup/assessment has been done; – Patients who are too poorly to be investigated – Patients where investigations eventually identify the primary – A true Unknown Primary! ...
Copyright Information of the Article Published Online TITLE Nothing
Copyright Information of the Article Published Online TITLE Nothing

... prostate cancer is much preferable to “overdiagnosis” which, it must be recognized, includes the strong possibility of a cure or long-term life and is most likely to avoid death from prostate cancer. It is clear that future research should attempt to differentiate between aggressive cancers and thos ...
PCA3: From basic molecular science to the clinical lab
PCA3: From basic molecular science to the clinical lab

... prostate cancer tissue led researchers to explore the potential use of PCA3 to non-invasively predict biopsy outcome. Hessels et al. [4] used time-resolved fluorescence (TRF) RTPCR to detect PCA3 mRNA in centrifuged urine sediments harvested from urine specimens that were collected following a digita ...
Prevention and Early Detection - Prostate Cancer Canada Network
Prevention and Early Detection - Prostate Cancer Canada Network

... In medicine, action taken to decrease the chance of getting a disease or condition. For example, cancer prevention includes avoiding risk factors (such as smoking, obesity, lack of exercise, and radiation exposure) and increasing protective factors (such as getting regular physical activity, staying ...
- Wiley Online Library
- Wiley Online Library

... infection.3 Abiraterone (with prednisone) and enzalutamide improved survival in patients with mCRPC who have previously received docetaxel.8 Abiraterone (with prednisone) and enzalutamide also showed superiority over prednisone alone or a placebo, respectively, improving overall survival, PSA progre ...
Tumor Antigens and Cancer Vaccines
Tumor Antigens and Cancer Vaccines

BRCA2 gene mutation and risk of aggressive prostate cancer
BRCA2 gene mutation and risk of aggressive prostate cancer

... Recently, aged 69 years, he came to our consultation for counselling on a targeted mutation search test for BRCA gene mutations. Recent genetic screening in his family revealed a c.6270_6271delTA (p.His2090Glnfs*9) mutation in the BRCA2 gene of his niece. Two of his nieces were diagnosed with breast ...
1 - Molecular Therapeutics for Cancer Ireland
1 - Molecular Therapeutics for Cancer Ireland

... Unfortunately, there are no effective treatment options for androgen-independent prostate cancer, with death usually occurring between 6-18 months after its development. Defining the precise mechanisms of resistance represents a key challenge facing clinicians and scientists. In collaboration with i ...
FINANCIAL IMPACT OF A CANCER DIAGNOSIS
FINANCIAL IMPACT OF A CANCER DIAGNOSIS

Individual`s Name
Individual`s Name

BME Cancer Communities by Rose Thompson
BME Cancer Communities by Rose Thompson

... Gaps in appropriate Support services Support is important and valued, especially if the support comes from someone who has a similar experience and cultural heritage. ...
Michael Fraser, Associate Director, CPC
Michael Fraser, Associate Director, CPC

... Our research is centred around prostate cancer and in particular the localised, potentially curable setting. We have a situation in prostate cancer where in the modern PSA era, 90% of guys are showing up in the clinic with localised disease with no evidence of metastatic spread. By and large, these ...
Prostate Cancer
Prostate Cancer

... Prostate cancer is a malignant tumour affecting males that starts in the cells of the prostate. The tumour grows slowly but can often be completely removed or successfully managed. The likelihood of developing prostate cancer increases after age 50 and is diagnosed most frequently in men aged 65 yea ...
Small Cell Carcinoma of Prostate: A Case Report of a Patient With a
Small Cell Carcinoma of Prostate: A Case Report of a Patient With a

... include ADT [16]. In some reports, it has been proposed that surgery is the first choice for early and confined lesions [19]. However, most SCC cases are already in advanced stages when diagnosed and some others with gross prostate, as in our case, it is difficult to achieve the best outcome with su ...
The Treatment Challenge of Hormone
The Treatment Challenge of Hormone

... The treatment of hormone-refractory prostate cancer (HRPC) is both challenging and rewarding as new targets are elucidated. As the most common malignancy in men the United States and the second leading cause of cancer death, the large number of patients requiring posthormonal therapy is increasing. ...
Prostate Cancer
Prostate Cancer

... Screening for CaP involves testing for levels of PSA and/or DRE. Screening of asymptomatic men is controversial. Debate centers on whether biologically and clinically significant cancers are being detected early enough to reduce mortality or, conversely, whether cancers detected by screening would c ...
A practical guide to prostate cancer diagnosis and management
A practical guide to prostate cancer diagnosis and management

... Screening for prostate cancer should involve both a digital rectal examination (DRE) and measurement of the serum PSA level. But when should screening start? The AUA recommends annual screening with DRE and serum PSA test starting at age 40 for all men with a life expectancy of more than 10 years. ...
A practical guide to prostate cancer diagnosis and management P ABSTRACT
A practical guide to prostate cancer diagnosis and management P ABSTRACT

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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