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dose of radiation and treatment outcome for prostate cancer
dose of radiation and treatment outcome for prostate cancer

... conforms more to the shape of the cancer. The dose is another issue. It can be normal, lower or higher. Conformal radiation should allow delivery of higher dose treatment. Of course the doctor should discuss with the patient the intent planned. Higher doses have been felt in the past to give higher ...
2012-11-30 Mammography Muddle
2012-11-30 Mammography Muddle

... early stage cancers that would progress to late stage cancers if not detected. And so, each early stage cancer found through screening should- they tell us- be one less late stage cancer. Over the past several decades, that has not been the case; the rise in incidence of early stage cancers is much ...
Prostate Cancer Management and Referral Guidance
Prostate Cancer Management and Referral Guidance

... the result of BPH, but prostatitis can cause a significant and rapid rise in PSA. A PSA >20.0 ng/mL means a cancer is highly likely to be present and metastases can sometimes already be demonstrated on bone or CT scan. Prostatitis is the most common alternative cause of this level of PSA elevation. ...
Document
Document

... Prostate cancer is the most common non-cutaneous malignancy and the second leading cause of cancer mortality amongst men in the Western world (1). Up to 40% of men diagnosed with prostate cancer will eventually develop metastatic disease (1). Although androgen deprivation is the standard of care for ...
Men With Favorable- Risk Prostate Cancer
Men With Favorable- Risk Prostate Cancer

... A very important consideration for men diagnosed with favorable-risk prostate cancer is the possibility of underestimating the true grade and/or volume of the tumor. Previous work from MUSIC, and elsewhere, has determined that information available at the time of diagnosis (e.g., PSA, results of dia ...
ambatipudibaabtandon_mallick_8816-2
ambatipudibaabtandon_mallick_8816-2

... Currently the vast majority of research pertaining to biomarkers is reported by the scientific community in the form of research papers. While this format presents information in a manner that can be read by humans, it makes collecting important information found from many research papers difficult. ...
ASCO GU 2010
ASCO GU 2010

EARLY DIAGNOSIS OF PROSTATE CANCER
EARLY DIAGNOSIS OF PROSTATE CANCER

18F-Choline: Is shine-through effect an issue for
18F-Choline: Is shine-through effect an issue for

... Measured Tumor SUV (g/l) ...
Prostate Cancer Working Group Report
Prostate Cancer Working Group Report

... number of candidates for screening is 25 000 per year, and about 40 prostate cancer patients are diagnosed per year. The problem is the low exposure rate for the screening, which reaches only 20% of the candidates. Of the total patients diagnosed with prostate cancer at Kanazawa University Hospita ...
Options for treatment of recurrent prostate cancer
Options for treatment of recurrent prostate cancer

Oncogenes - Hormone Restoration
Oncogenes - Hormone Restoration

Prostate cancer and exercise - Exercise Is Medicine ® Australia
Prostate cancer and exercise - Exercise Is Medicine ® Australia

... If you have been diagnosed with prostate cancer, you should aim to meet or exceed the following: Do continuous or intermittent aerobic exercise for 20 to 60 minutes per session, three to five times per week at 60–90% of your maximal heart rate (the maximal heart rate is estimated as 220 minus your a ...
Guideline for referral of patients with suspected prostate cancer by
Guideline for referral of patients with suspected prostate cancer by

... rostate cancer is the most common cancer diagnosed in men and it is the third leading cause of death due to cancer in men in Canada.1 However, in most men the disease progresses slowly over time, and the 5-year survival rate is 96% in Canada.1 Because some men are diagnosed with prostate cancer but ...
Trial of RucaparIb in ProsTate IndicatiONs 2
Trial of RucaparIb in ProsTate IndicatiONs 2

... PATIENT ELIGIBILITY ...
Prostate Trouble: Steps to Improving the Flow
Prostate Trouble: Steps to Improving the Flow

Cancer Screening Cancer screening
Cancer Screening Cancer screening

... Prostate Cancer Screening • DRE • Most widely used and oldest technique for detection of prostate cancer • Wide ranges of sensitivity (33%-69%) and specificity (49%-97%) • Serum PSA level • Allows earlier detection of prostate cancer • Normal PSA values are found in 1/3 of localized tumors (false n ...
Improving the surgical treatment of high‐risk localised or locally
Improving the surgical treatment of high‐risk localised or locally

... cases in the first report were largely clinically detected with proportionally higher stage disease, while those in the Wilt study were mainly screen detected with a high proportion of men with low-risk characteristics. The majority of the evidence currently available is from published case series, ...
Prediction of Prostate Cancer for Patients Receiving Finasteride
Prediction of Prostate Cancer for Patients Receiving Finasteride

... A PSA test and DRE were performed annually. At annual visits, study participants were recommended to undergo prostate biopsy if DRE was abnormal or if PSA value for men receiving placebo exceeded 4.0 ng/mL. In the finasteride group, to achieve similar rates of biopsy recommendation in the two study ...
sca clinical practice guideline for prostate cancer
sca clinical practice guideline for prostate cancer

... introduction and increasing use of the prostatic specific antigen (PSA) test in the late 1980s to early 1990s. In Saskatchewan, it is estimated that 890 new patients will be diagnosed with prostate cancer in 2008 and 230 will die of it. The estimated 2008 age-adjusted incidence rate in the province ...


Hormone resistant malignancy status
Hormone resistant malignancy status

... contribute to the decrease in lean body mass and the. Rabeprazole sodium 20 mg gastroresistant tablets - Summary of Product Characteristics (SPC) by Consilient Health Ltd. Menopause is diagnosed after 12 months of amenorrhea. Hormonal changes and clinical symptoms occur over a period leading up to a ...
Erectile Dysfunction
Erectile Dysfunction

... prostate cancer involves the postponement of immediate therapy, with definitive treatment used if there is evidence that the patient is at increased risk for disease progression.”  Why? With PSA screening, we are finding more low risk prostate cancers.  Prostate cancer is often detected when it is ...
Prostate Cancer - Toward Optimized Practice
Prostate Cancer - Toward Optimized Practice

... from 1.2% to 4.5% while the false positive rate also increased from 3.3% to 11.1%.17 Of those with a false positive PSA result, greater than 50% of patients will have another false positive PSA result. Men with an initial false positive are also more likely to have prostate cancer identified in subs ...
PSA and beyond: Biomarkers in prostate cancer
PSA and beyond: Biomarkers in prostate cancer

... after treatment.17 Other investigators have found that a PSA level less than 1.0 ng/mL before age 60 predicts a low lifetime risk of metastasis and death from prostate cancer. 18 Men in this category may harbor prostate cancer, but the disease is unlikely to become life-threatening. These men could ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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