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Radium-223 dichloride - Efficacy and mode-of
Radium-223 dichloride - Efficacy and mode-of

... (Fig. 2). PINP was significantly lower 6 weeks after treatment start, corresponding to the decreased number of osteoblasts observed in histomorphometry analyses (Fig. 4). The significantly lower PSA values were apparent as early as two weeks following the first dose, indicating that in addition to r ...
Castrate resistant prostate cancer: the future of anti
Castrate resistant prostate cancer: the future of anti

... symptomatic metastatic (specifically to bone) castration resistant prostate cancer pre- or post-docetaxel chemotherapy showed a 3 months survival advantage over placebo [13] and its role in the clinic is awaited when its approval occurs. Abiraterone acetate is an irreversible inhibitor of 17 α-hydro ...
Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Is
Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Is

... Consideration may be given to postoperative radiotherapy for patients who are suspected to have local recurrence because of a slow rise or no decrease in postoperative PSA levels [5]. On the other hand, distant metastasis should be treated by systemic therapy. It is often difficult to distinguish be ...
Nutricao e o Cancro da Prostata
Nutricao e o Cancro da Prostata

... Components of crucifers (isothiocyanates, indole 3carbinols) and tomatoes (carotenoids): ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

Prostate cancer – what do we see and how do we see it?
Prostate cancer – what do we see and how do we see it?

introduction - Semeiotica Biofisica
introduction - Semeiotica Biofisica

... The PCR is a powerful instrument that uses smallest amount of DNA for studying details. PCR-transcriptasi-inverse (the RT-PCR) employs the complementary conversion of mRNA to DNA (DNA), followed from the amplification of the DNA, product to the ends of the analysis. The prostatic cells express elev ...
Cancer
Cancer

Uncovering Genetic Pathways to Prostate Cancer
Uncovering Genetic Pathways to Prostate Cancer

... in the gene expression profiles of normal prostate and seminal vesicle epithelial cells in order to identify the pathways leading to the development of prostate cancer. This led to the identification of a new cancer biomodule unique to prostate epithelial cells. A biomodule is a network of genes con ...
Basics of Treatment for Prostate Cancer
Basics of Treatment for Prostate Cancer

... It is important to have regular PSA tests to monitor your PSA level for any changes, even after the prostate gland is removed, since some cancer cells may remain in the body after surgery and they can produce PSA. As well, a small amount of prostate tissue may remain and it can produce PSA also. ...
3074 - Emerson Statistics
3074 - Emerson Statistics

... variable. Log transformation is often appropriate for biological values which may be produced exponentially as, for example, a cancer grows. The untransformed nadir PSA value is highly skewed, and the transformation deemphasizes the largest values. The transformed variable would be expected to have ...
The Female Reproductive System
The Female Reproductive System

... a. Weak or interrupted urine flow b. A need to urinate frequently, especially at night C. Some of these symptoms may be caused by prostate enlargement, which is common as men age without presence of a tumor; called benign prostatic hyperplasia (BPH) 1. Treated with medication 2. Only way to distingu ...
Katherine Turner`s essay
Katherine Turner`s essay

... Natural History of the Disease “The natural history of the condition...should be adequately understood”; this cannot be said of prostate cancer (Burford et al., 2010.). Whilst some will men die of prostate cancer, many will die with prostate cancer of other causes. The disease‟s unpredictability pos ...
www.bccancer.ca www.phsa.ca
www.bccancer.ca www.phsa.ca

... tumor- and treatment-induced immune response and on modifying these responses to maximize treatment outcomes. The successful candidate will be a radiation oncologist who has interest in taking novel treatment concepts from the laboratory into the clinic. Experience in grant and manuscript preparatio ...
Genomic Health Demonstrates the Importance of Utilizing Multiple
Genomic Health Demonstrates the Importance of Utilizing Multiple

... that can inform critical treatment decisions and individualize patient care." In the prostate cancer study, researchers at the University of California, San Francisco (UCSF) conducted an analysis of 395 patient samples to evaluate the ability of the Oncotype DX Genomic Prostate Score (GPS) to predic ...
Module-3: Reducing Your Cancer Risk
Module-3: Reducing Your Cancer Risk

... the prostate gland. The prostate is a gland found only in men. The prostate is about the size of a walnut. It is just below the bladder and in front of the rectum. ...
Prostate Cancer - COSHAR Foundation
Prostate Cancer - COSHAR Foundation

... Thank you so much for your question as this is a major health risk for men. Let’s start with the basics: The prostate is a muscular, walnut-sized gland that surrounds part of the urethra, the tube that takes urine and sperm out of the body. A gland is a group of cells that secretes chemicals that ac ...
Benign prostatic hyperplasia: prevalence and diagnosis 321 Urology
Benign prostatic hyperplasia: prevalence and diagnosis 321 Urology

Mine - Edinburgh & Lothian Prostate Cancer Support Group
Mine - Edinburgh & Lothian Prostate Cancer Support Group

Integrative medicine is an approach to health care
Integrative medicine is an approach to health care

Embargoed until 00.01, March 1 Ref: NR0711 Page 1 of 3 Prostate
Embargoed until 00.01, March 1 Ref: NR0711 Page 1 of 3 Prostate

... Kyran Bracken said: “So many of us will be touched by cancer in our lifetime, yet some forms of cancer are more widely spoken about than others. This Prostate Cancer Awareness Month, I am proud to add my voice to the thousands of others who will be taking to the streets to declare ‘I’m aware’. It is ...
Guidelines for Management of Prostate Cancer
Guidelines for Management of Prostate Cancer

Trends in prostate cancer incidence and mortality: What is the role of
Trends in prostate cancer incidence and mortality: What is the role of

... PSA testing was increasingly used in NI before 1999, but no rise in incidence until 1999 very low biopsy rate in NI in 1999; incidence rose as biopsy rate rose higher biopsy rate in the RoI – and higher incidence in RoI, age-specific trends in incidence mirror those for biopsies evidence that thresh ...
TREATMENT OF HORMONE-REFRACTORY PROSTATE CANCER
TREATMENT OF HORMONE-REFRACTORY PROSTATE CANCER

... CT scan 14 days after the first Gendicine® urethral infection and died of renal failure resulting treatment demonstrated that the prostate tumor disfrom the use of anaminoglycoside antibiotics. appeared and no new lesion was found at his prostate thereafter (Figure 2). The symptom of incaDiscussion ...
For prostate cancer - Advanced Studies in Nursing
For prostate cancer - Advanced Studies in Nursing

... • TAX 327 compared 2 docetaxel schedules (weekly and every 3 weeks) with mitoxantrone and prednisone; median survival for the every-3-weeks docetaxel arm was 18.9 months vs 16.5 months for the mitoxantrone arm (P = .009) • Mitoxantrone with prednisone has been shown to provide palliative benefit in ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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