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Androgen receptor aberrations and abiraterone/enzalutamide
Androgen receptor aberrations and abiraterone/enzalutamide

... However, is the presence of aberrant AR uniformly associated with treatment resistance to ARdirected therapy? A study by Bernemann et al. in a recent issue of European Urology reported that some patients (4/21) with putatively AR-V7-positive CTC13 achieved 50% PSA reductions to abiraterone/enzaluta ...
AUA Releases Guideline on Early Detection of Prostate Cancer
AUA Releases Guideline on Early Detection of Prostate Cancer

... should weigh the benefits of preventing mortality in one man for every 1,000 screened over 10 years against the possible harms of screening and treatment. Therefore, the AUA strongly recommends shared decision making in men 55 to 69 years of age who are considering PSA screening, with the decision b ...
PROSTATE CANCER
PROSTATE CANCER

...  Second-most-common cause of cancer ...
Imaging modalities in prostate cancer
Imaging modalities in prostate cancer

Should baseline PSA testing be performed in men aged 40 to detect
Should baseline PSA testing be performed in men aged 40 to detect

Slide 1
Slide 1

Fact sheet: PSA test - Andrology Australia
Fact sheet: PSA test - Andrology Australia

Gene Section ELAC2 (elaC homolog 2 (E. coli)) in Oncology and Haematology
Gene Section ELAC2 (elaC homolog 2 (E. coli)) in Oncology and Haematology

09 Nevin Murray Prostate Cancer
09 Nevin Murray Prostate Cancer

... metastases (≥ 4 bone mets with ≥ 1 outside spine/pelvis or visceral mets) or poor prognosis  Consider in patients with non-high volume disease/good prognosis but risk vs. benefit ratio needs to be considered  Do not consider in patients without metastatic disease ...
Support Group for Gay and Bisexual Men Prostate Cancer
Support Group for Gay and Bisexual Men Prostate Cancer

... The PSA is a simple blood test that measures the level of Prostate Specific Antigen in the blood. Your GP will explain to you the meaning of the results and any further testing that may be required. The DRE (or Digital Rectal Examination) is a physical examination that enables your doctor to check t ...
Prostate-Specific Antigen Density and Gleason Score Predict
Prostate-Specific Antigen Density and Gleason Score Predict

... Various preoperative parameters, such as PSA, PSArelated parameters, and prostate biopsy-based Gleason scores, may be predictive of tumor stage in prostate cancer. Since the incidence of this disease has increased as a consequence of widespread PSA screening, more patients are undergoing radical pro ...
Prostate Problems - ROTARY CLUB of CLAYTON Inc
Prostate Problems - ROTARY CLUB of CLAYTON Inc

... No one knows why the prostate gets bigger, but it may be linked to hormone changes as men age. Prostate cancer This is the most common cancer in Australian men and the second most common cause of cancer-related death. Prostate cancer can have the same signs and symptoms as BPH. The prostate can have ...
PROSTATE CANCER SUPPORT
PROSTATE CANCER SUPPORT

... Helping men deal with the diagnosis and treatment of prostate cancer. Funding research into prostate cancer and, Raising awareness about prostate cancer in the general community. ...
Component3/Unit10/Lecture10b-Audio Transcript 1. Slide 1
Component3/Unit10/Lecture10b-Audio Transcript 1. Slide 1

Nuclear Medicine: Prostate Cancer
Nuclear Medicine: Prostate Cancer

... Prostate cancer Definition Prostate cancer originates within the prostate gland when abnormal cells divide at an unrestricted rate. According to the American Cancer Society it is estimated that there were more than 240,000 new cases of prostate cancer and 33,000 deaths from prostate cancer in 2011 ( ...
Wise choices 1 in urology
Wise choices 1 in urology

PG12-14 Cooper Lay summary Principal Investigator: Professor
PG12-14 Cooper Lay summary Principal Investigator: Professor

... We aim to make a new therapy for treatment of advanced/metastatic prostate cancer. We will make special particles called nanoparticles that will contain our newly developed SK1 inhibitors together with a standard docetaxel chemotherapy drug. These nanoparticles will ensure the targeted delivery of t ...
A Phase III, Randomized, Double-Blind, Placebo
A Phase III, Randomized, Double-Blind, Placebo

... • No previous morphine or strong pain killers for prostate cancer ...
PCWA INC EXERCISE CLUB FOR PROSTATE CANCER
PCWA INC EXERCISE CLUB FOR PROSTATE CANCER

... Leederville, with a new hub at UWA’s Exercise and Performance Centre, Parkway, Entrance #4, Nedlands. A small fee of $10/session will provide $5/person to the payment of our instructor and the remaining $5/per person is to be donated to ongoing Prostate Cancer Research at UWA. (PROST!). (Max 15 peop ...
Document - Herts Valleys CCG
Document - Herts Valleys CCG

... Practice Nurse to introduce her/himself to patient, review patients End of Treatment Summary & Follow Up Protocol and confirm that it is the correct patient. Offer partner or carer to be present at consultation Discuss patients immediate concerns ...
Is Prostate Cancer Screening Right for Me?
Is Prostate Cancer Screening Right for Me?

... Not necessarily. Less than one-third of high PSA results are caused by prostate cancer. A prostate biopsy (tissue sample) is the only way to know for sure if you have prostate cancer. However, your doctor may want to repeat your PSA or do other testing. ...
PROSTATE CANCER - Cancer Research UK
PROSTATE CANCER - Cancer Research UK

... • difficulty peeing • a sense of not being able to completely empty the bladder • difficulty getting an erection or erection problems. Another warning sign might be having blood in your pee. These symptoms are more often caused by problems that are much less serious than cancer. But if you develop a ...
Abstract
Abstract

... agents may result in similar response rates. Megestrol acetate (MA) has been shown to be effective therapy for metastatic prostate cancer. This synthetic progestin blocks androgen receptors and lowers the serum androgen levels through inhibition of release of luteinizing hormone and 5 alpha-reductas ...
Prostate Specific Antigen and Prostate Cancer Screening: Update
Prostate Specific Antigen and Prostate Cancer Screening: Update

... Prostate cancer is the most common cancer among men in the United States, killing 34,000 men per year, ranking it the second deadliest cancer of males, following lung cancer.1 Such a devastating disease must have a highly sophisticated screening tool and straightforward recommendations in place, rig ...
Tumor markers
Tumor markers

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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