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Overview of prostate cancer
Overview of prostate cancer

... • Highly selected patients with very high-risk localised Prostate Cancer (cT3b-T4 N0 or any T N1) in the context of multimodality treatment. ...
Office Examination - Healing Our Communities
Office Examination - Healing Our Communities

what we`ve learnt about prostate cancer in 2013 – ask a urologist!
what we`ve learnt about prostate cancer in 2013 – ask a urologist!

... 1. A simple PSA blood test in your 40s can save your life and may reduce the number of tests you need in the future. A new study showed a PSA (prostate-specific antigen) test at age 45 can be used to predict a man’s long-term risk of developing an aggressive prostate cancer. The study followed up mo ...
Carcinoma of the prostate Carcinoma of the prostate is the
Carcinoma of the prostate Carcinoma of the prostate is the

... protection from subsequent carcinoma. Types of prostate cancer • Microscopic latent cancer found on autopsy or at cystoprostatectomy •Tumours found incidentally during TURP (ha and Tlb); or following screening by PSA measurement — T1c •Early, localised prostate cancer (T2) • Advanced local prostate ...
Prostate cancer (hormone-refractory) - docetaxel: Final scope
Prostate cancer (hormone-refractory) - docetaxel: Final scope

... new cases diagnosed in 2000. It is also the second most common cause of male cancer mortality, with 9940 deaths in 2002. The number of diagnoses has been increasing in recent years, but it is thought that this is due to greater monitoring of prostate specific antigen (PSA) levels in the blood, which ...
Early Detection of Prostate Cancer
Early Detection of Prostate Cancer

... The risk of prostate cancer increases with age, especially after the age of 50.7 Men who have a family history of prostate cancer are more likely to develop prostate cancer.8 American evidence suggests that men of African heritage are at higher risk of prostate cancer.9 Physicians are encouraged to ...
Treatment of castration-resistant prostate cancer
Treatment of castration-resistant prostate cancer

... blood (intravenous, IV) every 4 weeks for a total of 6 treatments • Radium-223 goes to where the cancer has spread in the bone; it gives off radiation in the areas where the cancer is causing damage • Radium-223 therapy can improve patient survival and can also delay and reduce t ...
APPLICATION
APPLICATION

Use of Advanced Treatment Technologies Among Men at
Use of Advanced Treatment Technologies Among Men at

... Surveillance, Epidemiology, and End Results region. Use of advanced treatment technologies significantly increased among prostate cancer patients with low-risk disease, high risk of noncancer mortality, and both low-risk disease and high risk of noncancer mortality (P < .001 for trend). Conversely, ...
Metastatic disease: hormone therapy
Metastatic disease: hormone therapy

Malignant ascites with omental metastasis
Malignant ascites with omental metastasis

CVPCSG newsletter 11.11 - Prostate Cancer Canada
CVPCSG newsletter 11.11 - Prostate Cancer Canada

What is the prostate gland?
What is the prostate gland?

... If you are concerned about prostate cancer would you rather know you have cancer, or not know? If your PSA was normal would you be reassured? If you are found to have a slow growing prostate cancer and do not need to have to have treatment would you rather know you have cancer, or not know? If you h ...
Optimal use of prostate specific antigen for prostate cancer screening
Optimal use of prostate specific antigen for prostate cancer screening

... There is strong evidence from previous reports that screening men for PCa in the PSA era should be stopped earlier than current guidelines would suggest. According to a population-based study from the pre-PSA era by Albertsen et al. 20, a significant number of PCa identified today (in the PSA era) w ...
2ww Urology Outpatients
2ww Urology Outpatients

...  With a hard, irregular prostate typical of a prostate carcinoma. Prostate-specific antigen (PSA) should be measured and the result should accompany the referral. (An urgent referral is not needed if the prostate is simply enlarged and the PSA is in the age-specific reference range).  With a norma ...
Prostate Cancer - Global Drug Forecast and Market Analysis to 2023 for the $8.2 Billion Market
Prostate Cancer - Global Drug Forecast and Market Analysis to 2023 for the $8.2 Billion Market

Immunotherapy and gene therapy in
Immunotherapy and gene therapy in

... (metastasized) (mHRPC), showing an increase of the lifespan (versus placebo) of approximately 4 months (on average from 21 to 25 months) in all three phases of clinical testing. Both the principle and the course of treatment consist of three steps [5,6]:  Extracting a population of lymphocytes, mai ...
Alaska Native Tribal Health Consortium NEWSLETTER Business Resource Center SEPTEMBER IS PROSTATE
Alaska Native Tribal Health Consortium NEWSLETTER Business Resource Center SEPTEMBER IS PROSTATE

Screening for Prostate Cancer - New England Journal of Medicine
Screening for Prostate Cancer - New England Journal of Medicine

... Observation Trial (PIVOT),6 active surveillance could be considered. If intermediate or high-risk prostate cancer is diagnosed (PSA level ≥10, Gleason score ≥7, or disease stage ≥T2b), given the potential survival benefit with treatment versus observation in PIVOT,6 the patient should be counseled r ...
Screening for Prostate Cancer Recommend PSA Screening
Screening for Prostate Cancer Recommend PSA Screening

... Observation Trial (PIVOT),6 active surveillance could be considered. If intermediate or high-risk prostate cancer is diagnosed (PSA level ≥10, Gleason score ≥7, or disease stage ≥T2b), given the potential survival benefit with treatment versus observation in PIVOT,6 the patient should be counseled r ...
Screening for Prostate Cancer Recommend PSA Screening
Screening for Prostate Cancer Recommend PSA Screening

... Observation Trial (PIVOT),6 active surveillance could be considered. If intermediate or high-risk prostate cancer is diagnosed (PSA level ≥10, Gleason score ≥7, or disease stage ≥T2b), given the potential survival benefit with treatment versus observation in PIVOT,6 the patient should be counseled r ...
(HRPC): Only Chemotherapy?
(HRPC): Only Chemotherapy?

... showed an inhibitory effect on prostate cancer bone metastases by blocking proteolytic activity of the matrix, cell adhesion, and possibly cancer cell growth [9]. Multicentric randomised trials of HRPC with bone metastases showed a significant reduction in skeletal-related events using zoledronic ac ...
PDF - Canadian Task Force on Preventive Health Care
PDF - Canadian Task Force on Preventive Health Care

... • In many cases prostate cancer does not, and will not, pose a threat to a man’s life. ISN’T IT BETTER TO GET SCREENED THAN TO DO NOTHING? • Screening with the PSA often leads to further testing, which carries with it its own serious risks and problems. • For example, a biopsy involves a number of p ...
Prostate Cancer Information and Support Resources
Prostate Cancer Information and Support Resources

... It is now in a newly updated edition. The Canadian Guide to Prostate Cancer. Jamnicky, Leah and Nam, Robert. 2nd edition. Mississauga, ON: John Wiley & Sons Canada, 2013. This book provides detailed information about all prostate cancer treatments, including the benefits and disadvantages of each tr ...
PCa PowerPoint Presentation - Prostate Cancer Resource Center
PCa PowerPoint Presentation - Prostate Cancer Resource Center

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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