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REGULATION BY EXERCISE OF SKELETAL MUSCLE CONTENT
REGULATION BY EXERCISE OF SKELETAL MUSCLE CONTENT

... many signals generated during exercise are responsible for inducing the increase in mitochondrial biogenesis. It was, therefore, necessary to use experimental models in which the signals generated in muscle during exercise can be studied individually. The models that have been used to study the sign ...
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL

... The folding of the inner membrane to form cristae increases its surface area, providing space for thousands of copies of the chain in each mitochondrion. Most components of the chain are proteins that exist in multiprotein complexes numbered I– ...
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL

... The folding of the inner membrane to form cristae increases its surface area, providing space for thousands of copies of the chain in each mitochondrion. Most components of the chain are proteins that exist in multiprotein complexes numbered I– ...
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL

... The folding of the inner membrane to form cristae increases its surface area, providing space for thousands of copies of the chain in each mitochondrion. Most components of the chain are proteins that exist in multiprotein complexes numbered I– ...
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL
CHAPTER 9 CELLULAR RESPIRATION: HARVESTING CHEMICAL

... The folding of the inner membrane to form cristae increases its surface area, providing space for thousands of copies of the chain in each mitochondrion. Most components of the chain are proteins that exist in multiprotein complexes numbered I– ...
Cellular Respiration: Harvesting Chemical Energy
Cellular Respiration: Harvesting Chemical Energy

... The folding of the inner membrane to form cristae increases its surface area, providing space for thousands of copies of the chain in each mitochondrion. Most components of the chain are proteins that exist in multiprotein complexes numbered I– ...
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BOOK NOTES ch9_sec3

... Section 3: Cellular Respiration ...
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... Lipid FACTS Lipids are energy rich and provides 9 kcal/gm dietary lipids 90% triacylglycerols (TAGs) also include cholesterol esters, phospholipids, essential unsaturated fatty acids; fat-soluble vitamins most dietary fat transported to adipose for storage dietary TAGs hydrolyzed in the intestine b ...
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... Absence of Oxygen? • 7.4 How Does the Oxidation of Glucose Form ATP? • 7.5 Why Does Cellular Respiration Yield So Much ...
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... Oxidative Phosphorylation •  The process that generates most of the ATP is called oxidative phosphorylation because it is powered by redox reactions •  Oxidative phosphorylation accounts for almost 90% of the ATP generated by cellular respiration •  A smaller amount of ATP is formed in glycolysis a ...
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... Glycolysis is the sequence of reactions that converts glucose into pyruvate with the concomitant production of a relatively small amount of ATP. Glycolysis can be carried out anerobically (in the absence of oxygen) and is thus an especially important pathway for organisms that can ferment sugars. Fo ...
Chapter 6 notes
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... 6.9 The citric acid cycle completes the oxidation of organic molecules, generating many NADH and FADH2 molecules • The citric acid cycle • is also called the Krebs cycle (after the GermanBritish researcher Hans Krebs, who worked out much of this pathway in the 1930s), • completes the oxidation of o ...
Chapter 16 The Citric Acid Cycle
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... • A 2-carbon unit Acetyl-CoA is added to the cycle • And two CO2 molecules leave (but they are different carbons…) • During the course of changes in the carbon skeleton and its oxidation state • And the transfer of energy to form GTP (aka. the “Canadian $”) and reducing power, as NADH and FADH2 • It ...
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Citrate cycle - 3.LF UK 2015

...   ATP / ADP   NADH / NAD+   ATP / ADP  GTP  succinyl-CoA ...
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... • Electrons are transferred from NADH or FADH2 to the electron transport chain • Electrons are passed through a number of proteins including cytochromes (each with an iron atom) to O2 • The electron transport chain generates no ATP directly • It breaks the large free-energy drop from food to O2 int ...
2.277 December 2004 Final Exam
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... 3) Phospholipid molecules in bilayers can move laterally and can also move from one side of the bilayer to the other. 4) Polar molecules can easily cross a phospholipid bilayer 5) All of the above are true ...
Chapter 9 - Slothnet
Chapter 9 - Slothnet

... • Ancient prokaryotes are thought to have used glycolysis long before there was oxygen in the atmosphere • Very little O2 was available in the atmosphere until about 2.7 billion years ago, so early prokaryotes likely used only glycolysis to generate ATP • Glycolysis is a very ancient process ...
Role of Carnitine in Lipid Metabolism
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... proteins needed for transport of long-chain fatty acids into the mitochondrial matrix has been reviewed (4) and will not be repeated at this time. The discovery that malonyl CoA is an inhibitor of carnitine palmitoyltransferase I has added to our understanding of the coordinated metabolic regulation ...
Medical faculty 2- d course Module 4 General principles of metabolism
Medical faculty 2- d course Module 4 General principles of metabolism

... D. Electron transport E. Glycolysis. ANSWER: C 46. A deficiency in thiamin causes the disease beriberi. Which might you expect to have a higher than normal blood concentration in an individual with this condition? A. Isocitrate B. Pyruvate C. Oxaloacetate D. Acetyl CoA E. Malate ANSWER: B 47. Compo ...
Biol 1406 notes Ch 9 8thed
Biol 1406 notes Ch 9 8thed

... For each acetyl group that enters the cycle, 3 NAD+ are reduced to NADH. In one step, electrons are transferred to FAD instead of NAD+. Then FAD accepts 2 electrons and 2 protons to become FADH2. In the cells of plants, bacteria, and a few animal tissues, the citric acid cycle forms an ATP molecule ...
ATP - Luzzago
ATP - Luzzago

... ATP synthase is the same in all living organisms. • It is a molecular motor with two parts: – F0 unit—the transmembrane H+ channel – F1 unit—projects into mitochondrial matrix; rotates to expose active sites for ATP synthesis ...
Adjeitey_Cyril _Nii-Klu_2013_ thesis
Adjeitey_Cyril _Nii-Klu_2013_ thesis

... UCP1 is a member of the mitochondrial transmembrane anion carrier protein superfamily and is required to mediate adaptive thermogenesis in brown adipose tissue (BAT). Once activated, UCP1 uncouples mitochondrial respiration from ATP synthesis, thereby wasting the protonmotive force formed across the ...
09_Lecture_Presentation
09_Lecture_Presentation

... • Electrons are transferred from NADH or FADH2 to the electron transport chain • Electrons are passed through a number of proteins including cytochromes (each with an iron atom) to O2 • The electron transport chain generates no ATP directly • It breaks the large free-energy drop from food to O2 int ...
File
File

... A) The conversion yields 32 ATP per pyruvate molecule. B) The conversion yields one NADH per pyruvate molecule. C) The conversion is needed to regenerate the molecules needed for glycolysis. D) A buildup of pyruvate in the surrounding environment would be too toxic. Answer: C Topic: 6.13 Skill: Know ...
File
File

... A) The conversion yields 32 ATP per pyruvate molecule. B) The conversion yields one NADH per pyruvate molecule. C) The conversion is needed to regenerate the molecules needed for glycolysis. D) A buildup of pyruvate in the surrounding environment would be too toxic. Answer: C Topic: 6.13 Skill: Know ...
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Mitochondrion



The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells. The word mitochondrion comes from the Greek μίτος, mitos, i.e. ""thread"", and χονδρίον, chondrion, i.e. ""granule"" or ""grain-like"".Mitochondria range from 0.5 to 1.0 μm in diameter. A considerable variation can be seen in the structure and size of this organelle. Unless specifically stained, they are not visible. These structures are described as ""the powerhouse of the cell"" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy. In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling, cellular differentiation, and cell death, as well as maintaining control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders, cardiac dysfunction, and heart failure. A recent University of California study including ten children diagnosed with severe autism suggests that autism may be correlated with mitochondrial defects as well.Several characteristics make mitochondria unique. The number of mitochondria in a cell can vary widely by organism, tissue, and cell type. For instance, red blood cells have no mitochondria, whereas liver cells can have more than 2000. The organelle is composed of compartments that carry out specialized functions. These compartments or regions include the outer membrane, the intermembrane space, the inner membrane, and the cristae and matrix. Mitochondrial proteins vary depending on the tissue and the species. In humans, 615 distinct types of protein have been identified from cardiac mitochondria, whereas in rats, 940 proteins have been reported. The mitochondrial proteome is thought to be dynamically regulated. Although most of a cell's DNA is contained in the cell nucleus, the mitochondrion has its own independent genome. Further, its DNA shows substantial similarity to bacterial genomes.
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