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Annexure `CD-01` L T P/S SW/FW TOTAL CREDIT UNITS 3 0 0 0 3
Annexure `CD-01` L T P/S SW/FW TOTAL CREDIT UNITS 3 0 0 0 3

... Mechanism of enzyme action – Lock and Key model and induced fit models. Coenzymes – cofactors – prosthetic groups of enzymes (TPP, NAD, NADP, FAD, ATP).Their importance in enzyme action. Mechanism of inhibition (competitive, non- and uncompetitive and allosteric) Immobilization of enzymes. Enzyme sp ...
8.1 – Cell Respiration
8.1 – Cell Respiration

... metabolised. The reaction occurs in the matrix. The pyruvate has one carbon atom removed to form CO2 through decarboxylation. It is also oxidised through the removal of oxygen. Combined, this is referred to as oxidative decarboxylation. One of the products is an acetyl group, which joins to the coen ...
Glycolysis PP
Glycolysis PP

... Glycolysis Was an Early Metabolic Process • Glycolysis certainly evolved in prokaryotes before oxygenation of the atmosphere • Probably one of the very first complex biochemical pathways (>3.5 BYA) • Evidence? – Almost universal. – No requirement for O2: it is an anaerobic process, even when used b ...
Peptide microarrays for detailed, high-throughput
Peptide microarrays for detailed, high-throughput

... was used for real-time detection of protein kinase A (PKA) for substrate identification and kinetic characterization of PKA (figure 1). Figure 2 shows a time course of peptide phosphorylation over 50 minutes. In this assay the IC50 of three PKA inhibitors, AMP–PNP, staurosporin, and PKA inhibitor pe ...
GLYCOLYSIS
GLYCOLYSIS

... • Glucokinase in liver acts as hexokinase in muscle • Phosphofructokinase responds to signal molecule F-2,6,-BP • Pyruvatekinase inhibited by ATP at low glucose levels ...
Protein regulation: The statistical theory of
Protein regulation: The statistical theory of

... ubiquitous molecular chaperone consisting of an N-terminal nucleotide-binding domain and a C-terminal substrate-binding ...
Metabolism
Metabolism

... large molecule into smaller units • Anabolic—describes the building of more complex molecules from smaller ones ...
Metabolic Adaptation - Washington State University
Metabolic Adaptation - Washington State University

... versus protein • Amino acids and carbohydrates are at about the same oxidation state – so although the exact pathways may vary from one amino acid to another, the yield of ATP from a gram of amino acid is about the same as the yield from a gram of glucose. • However, as in the example of the fly, am ...
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... eventually, cells. Aside from providing energy, carbohydrates also associate with both the phospholipids and proteins of cell membranes, in order to provide each cell with an “I.D. tag” for cell-to-cell recognition. ...
role of respiration in glycolysis, co2 and h20 production
role of respiration in glycolysis, co2 and h20 production

... The fate of dietary components after digestion and absorption constitutes intermediary metabolism. Metabolic pathways fall into three categories: 1. Anabolic pathway – synthesis of compound constituting body structure and machinery e.g. Protein synthesis 2. Catabolic pathway – involves oxidative pro ...
Biochemistry Quiz Multiple Choice Identify the letter of the choice
Biochemistry Quiz Multiple Choice Identify the letter of the choice

... b. DNA is to RNA. d. glucose is to starch. 2. A monosaccharide like glucose or fuctose is a a. carbohydrate. c. nucleic acid. b. lipid. d. protein. 3. Which of the following organic compounds is the main source of energy for living things? a. carbohydrates c. nucleic acids b. lipids d. proteins 4. W ...
Cellular Metabolism
Cellular Metabolism

... Recall the overall equation: C6H1206 + 6O2 = 6CO2 + 6H2O + 36ATP To accomplish this requires different processes at different places within the cell Step 1 – Glycolysis - formation of two pyruvates Step 2 – Pyruvate oxidative decarboxylation - formation of two acetyl CoA Step 3 – Citric Acid Cycle - ...
MEMBRANE-BOUND ELECTRON TRANSFER AND ATP
MEMBRANE-BOUND ELECTRON TRANSFER AND ATP

... synthesis of ATP by another transmembrane protein complex, as the protons return back across the IMM through this protein complex. ...
Powerpoint - Oregon State University
Powerpoint - Oregon State University

... kinase (activates it); and 8) production of glucose-1-phosphate by action of glycogen phosphorylase on glycogen. Bonus: second messenger: cAMP; first messenger: hormone ...
Midterm Outline2
Midterm Outline2

... explain osmosis in terms of WATER POTENTIAL). 5) Methods of active transport: endo/exocytosis, sodium-potassium pump. Chapter 8: Introduction to Metabolism 1) How can spontaneous/nonspontaneous reactions be described in terms of ∆G? 2) Structure of the ATP molecule. 3) What is a phosphorylation reac ...
Unit 3 Study Questions
Unit 3 Study Questions

... Animal cells accomplish cytokinesis by the process of _________________________. Plant cells accomplish cytokinesis by the formation of the ______________________. The __________________ (organelle) in an animal cell are responsible for the formation of the spindle apparatus. ______________ and ____ ...
Macromolecules  Note: If you have not taken Chemistry 11 (or if...
Macromolecules Note: If you have not taken Chemistry 11 (or if...

... Amino acids are categorized into three types as determined by the R group. Each type has characteristics which cause the amino acid to behave differently in different environments. This is important for the formation of the three dimensional shape of proteins. The shape of the protein is important f ...
Answer Key for the Supplemental Problem Set #1
Answer Key for the Supplemental Problem Set #1

... 2. During glycolysis, how many ADP molecules are converted to ATP. Explain this answer with regard to your answer to #1. 4 ADP molecules are converted into ATP. There is a net gain of only 2 ATP molecules because 2 are consumed during the first stage of glycolysis. 3. What are the three metabolicall ...
1. What is substrate level phosphorylation (vs. oxidative
1. What is substrate level phosphorylation (vs. oxidative

... 12. Beta-oxidation of fatty acids produces an important substrate for the TCA cycle. Name the substrate. ...
In order to gain 1lb in body fat over 1 year a person would have to
In order to gain 1lb in body fat over 1 year a person would have to

... 3. (4pts) What is the importance of the anaplerotic reactions of the TCA cycle? Anaplerotic reactions refers to the flow of intermediates out of “cycle” and their replenishment via alternative synthetic reactions (1 pt). As an example, if OAA or Malate were used in reactions other than those of the ...
Ch23_PT MULTIPLE CHOICE. Choose the one alternative that best
Ch23_PT MULTIPLE CHOICE. Choose the one alternative that best

... 12) The major function of the pentose phosphate pathway when nucleic acid synthesis is a priority is A) providing intermediates for the citric acid cycle. B) providing intermediates for glycogenesis. C) producing ribose. D) producing NADPH. E) meeting the need for large amounts of ATP. ...
M220 Lecture 11 - Napa Valley College
M220 Lecture 11 - Napa Valley College

... as glucose are oxidized, the hydrogens (with their electrons) that are lost, must be gained by other chemicals. These other chemicals are therefore reduced as they gain hydrogens. Coenzymes can receive these hydrogens (become reduced) to make enzymatic reactions work. These same coenzymes will later ...
Chapter 5
Chapter 5

... C. can directly form pyruvic acid. *D. Both can enter the Krebs cycle and can reversibly form ketone bodies. ...
Chapter 5
Chapter 5

... 4 hydrogens are removed from intermediates ...
Ch 26 Notes
Ch 26 Notes

... Gluconeogensis – In liver, making of new glucose –from protein and or fat Stimulated by cortisol, glucagons, epinephrine Liver disorders Hepatitis - inflammation - viral usually - 5 strains A most common - transmitted in large restricted groups & by foods B & C are sexually transmitted & by blood an ...
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Phosphorylation



Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).
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