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Opium Abuse and Its Management: Global Scenario
Opium Abuse and Its Management: Global Scenario

... is withdrawn abruptly and the detoxification begins using clonidine, anxiolytic and other medicines for symptomatic treatment. A social worker is also available to conduct psycho-education group sessions. Thus the treatment consisted of both pharmacological and non-pharmacological modalities. Prayer ...
ANNEXURE-3 14
ANNEXURE-3 14

... Appropriate cultures should usually be performed before initiating antimicrobial treatment in order to isolate and identify the organisms causing infection and to determine their susceptibility to piperacillin and tazobactam. Antimicrobial therapy should be adjusted, if appropriate, once the results ...
Toward Understanding the Biology of a Complex Phenotype: Rat
Toward Understanding the Biology of a Complex Phenotype: Rat

... housing lights on at 08:00 hr, the circadian phase in which testing occurred was not clear; in the present study, all testing and drug administration occurred between 10:00 and 17:00 hr. Weiss et al. (1999) recently reported that circadian time does not modif y either PPI or its disruption by apomor ...
FORM 10-K/A - corporate
FORM 10-K/A - corporate

... women’s health. Our marketed product and product development programs utilize our proprietary drug delivery technologies, which we believe are suited to applications in women’s health. These technologies consist of our bioadhesive delivery system (“BDS”), a polymer designed to adhere to epithelial s ...
Amphetamines Assay
Amphetamines Assay

... (MDMA) and methylenedioxyethylamphetamine (MDEA) in human urine (see Table 14). The assay contains monoclonal antibodies and is therefore less subject to interferences from amphetamine-like compounds than assays containing polyclonal antibodies. While interferences are reduced with this assay, like ...
YES NO 60% 40% 30% 30% 40% - Humulin® R (U-500)
YES NO 60% 40% 30% 30% 40% - Humulin® R (U-500)

... open-label, randomized trial conducted in the United States and Puerto Rico. This clinical trial compared two treatment regimens (three times daily (TID) versus twice daily (BID)) for U-500 insulin for replacement of high-dose U-100 insulin.1 ...
Pharmacokinetic and pharmacodynamic drug interactions
Pharmacokinetic and pharmacodynamic drug interactions

... J. Anke, I. Ramzan / Journal of Ethnopharmacology 93 (2004) 153–160 ...
Position Paper: Ipecac Syrup
Position Paper: Ipecac Syrup

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Stability and aerosolization of pressurized metered dose inhalers
Stability and aerosolization of pressurized metered dose inhalers

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Everolimus Novartis tablet ENG SmPC

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idarubicin
idarubicin

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P-Glycoprotein functional activity in peripheral blood lymphocytes. Role of immunosuppressants,

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Diclofenac Sodium 4% Spray Gel
Diclofenac Sodium 4% Spray Gel

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Diazepam - EWU Institutional Repository
Diazepam - EWU Institutional Repository

... of drugs. Diazepam and other benzodiazepines act by enhancing the effects of gamma-amino butyric acid (GABA) in the brain. GABA is a neurotransmitter (a chemical that nerve cells use to communicate with each other) that inhibits activity in the brain. Diazepam is used for the treatment of disorders ...
PropoFlo - zoetisUS.com
PropoFlo - zoetisUS.com

... source of exposure and seek medical attention. Respiratory depression should be treated by artificial ventilation and oxygen. ...
The PSMATCH Procedure
The PSMATCH Procedure

... (exposure) group or a control (non-exposure) group. Random assignment ensures that the distribution of the covariates is the same in both groups, and the treatment effect can be estimated by directly comparing the outcomes for the subjects in the two groups. In contrast, the subjects in an observati ...
Wolfe - Intranasal naloxone in safe injection setting
Wolfe - Intranasal naloxone in safe injection setting

... There is also an epidemic (especially in my country, but increasingly here as well) related to accidental prescription opiate overdoses There is time to intervene if an easy, effective intervention is instituted in the public domain. ...
Medicinal Value of the Caterpillar Fungi Species
Medicinal Value of the Caterpillar Fungi Species

... ABSTRACT: This review looks in depth at the history and medicinal value of the Cordyceps species, especially C. sinensis. The C. sinensis medicinal species, with a long history of use, has only been found growing from the head of one type of subterranean caterpillar, at high altitudes, in the Qingha ...
Key Aspirin Information
Key Aspirin Information

... immediate effect of aspirin in the stomach with food, antacids, buffered brands or coated products such as Ecotrin, Easprin, or Therapy Bayer Caplets may help a little with indigestion and heartburn. But aspirin also lowers body-wide levels of hormone-like chemicals (prostaglandins). Prostaglandins ...
Piracetam - Rebound Health
Piracetam - Rebound Health

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Understanding Anesthesiology - The Global Regional Anesthesia
Understanding Anesthesiology - The Global Regional Anesthesia

... on to have two small tumours successfully removed from his neck. Dr. Long received the world’s first anesthetic fee: $0.25. Since then, the specialty of anesthesiology and the role of the anesthesiologist has grown at a rapid pace, particularly in the last several decades. In the operating room the ...
Actions of bufalin and cinobufotalin, two bufadienolides respectively
Actions of bufalin and cinobufotalin, two bufadienolides respectively

... the addition of non-labelled ouabain, bufalin and cinobufotalin are shown in Fig. 1.All nine blood samples were tested separately over the range 10-9-10-6 mol/l for ouabain and cinobufotalin and 10- l o - l O - h mol/l for bufalin. The curve with bufalin is shifted to the left compared with that of ...
Amphotericin B as a mycolic acid specific targeting agent in tuberculosis
Amphotericin B as a mycolic acid specific targeting agent in tuberculosis

... I would humbly like to thank the following individuals and organizations for their support towards my completion of my MSc. degree. Most importantly, our Creator and King, for the guidance and support in the good and trying times and never leaving my side. Prof. J.A. Verschoor my promoter, for his d ...
Pharmacokinetic interactions of carbamazepine with some
Pharmacokinetic interactions of carbamazepine with some

... in few cases in the groups on CBZ+VPA and CBZ+LTG bitherapy. In a case of bitherapy with CBZ+LTG, the Cmax of total CBZ was higher than therapeutic value averaging 11.37±4.78 g/ml. The Cmax values of Cmin, Cmax and Cmean were the highest in CBZ+VGB bitherapy group. Two of them, maximum and mean leve ...
BuPROPion Hydrochloride Extended
BuPROPion Hydrochloride Extended

... Pharmacodynamics: Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine, and does not inhibit monoamine oxidase or the re-uptake of serotonin. The mechanism by which bupropion hydrochloride extended-release tablets (SR) enhances the ability of patients to abs ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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