AusPAR Nivolumab - Therapeutic Goods Administration
... A new AusPAR will be developed to reflect changes to indications and/or major variations to a prescription medicine subject to evaluation by the TGA. ...
... A new AusPAR will be developed to reflect changes to indications and/or major variations to a prescription medicine subject to evaluation by the TGA. ...
Is ecstasy MDMA? - Department of Psychology
... complaints from ecstasy users about their MDMA supplies. A survey of 100 American college users reported no concerns over their purity (Peroutka et al. 1988; Peroutka 1989). Similarly in Australia, Solowij et al. (1992) noted that there were “high levels of purity in Sydney”, although it was recogni ...
... complaints from ecstasy users about their MDMA supplies. A survey of 100 American college users reported no concerns over their purity (Peroutka et al. 1988; Peroutka 1989). Similarly in Australia, Solowij et al. (1992) noted that there were “high levels of purity in Sydney”, although it was recogni ...
Dexmedetomidine Use in General Anaesthesia
... and propofol based anesthesia. Sixty patients were divided into four groups according to the anesthetic to be administered: sevoflurane, propofol, sevoflurane and dexmedetomidine and propofol and dexmedetomidine as maintenance general anesthetics. The main findings of this study are that dexmedetomi ...
... and propofol based anesthesia. Sixty patients were divided into four groups according to the anesthetic to be administered: sevoflurane, propofol, sevoflurane and dexmedetomidine and propofol and dexmedetomidine as maintenance general anesthetics. The main findings of this study are that dexmedetomi ...
Assessment of zopiclone - World Health Organization
... Appropriate studies which could provide rationale for the use of hypnotics over prolonged periods have been lacking. Until recently any controlled study did not extend to more than to 2-3 weeks and very exceptionally beyond that (Wagner and Wagner, 2000; Walsh, 2004). This need has become to be met ...
... Appropriate studies which could provide rationale for the use of hypnotics over prolonged periods have been lacking. Until recently any controlled study did not extend to more than to 2-3 weeks and very exceptionally beyond that (Wagner and Wagner, 2000; Walsh, 2004). This need has become to be met ...
6. Kelly CP. A 76-year-old man with recurrent
... cross-reactivity between penicillins and other beta-lactams.”20 The rate of cross-reactivity between penicillins and cephalosporins is now considered to be as low as 0.6%.21 It typically occurs between penicillins and the first generation cephalosporins. Cross-reactivity between penicillins and the ...
... cross-reactivity between penicillins and other beta-lactams.”20 The rate of cross-reactivity between penicillins and cephalosporins is now considered to be as low as 0.6%.21 It typically occurs between penicillins and the first generation cephalosporins. Cross-reactivity between penicillins and the ...
ANTILIPEMICS 2012 - students [Read
... NCEP ATP-III LDL-cholesterol goals and cutpoints for therapeutic lifestyle changes and drug therapy in different risk categories ...
... NCEP ATP-III LDL-cholesterol goals and cutpoints for therapeutic lifestyle changes and drug therapy in different risk categories ...
P1507962 Piperacillin And Tazobactam For Injection Leaflet
... --------------------------------------------------USE IN SPECIFIC POPULATIONS------------------------------------------------Dosage in patients with renal impairment (≤ 40 mL/min of CRCL) should be reduced to the degree of actual renal function impairment. (2.3, 8.6) See 17 for PATIENT COUNSELING IN ...
... --------------------------------------------------USE IN SPECIFIC POPULATIONS------------------------------------------------Dosage in patients with renal impairment (≤ 40 mL/min of CRCL) should be reduced to the degree of actual renal function impairment. (2.3, 8.6) See 17 for PATIENT COUNSELING IN ...
Charles University in Prague Faculty of Pharmacy in Hradec Králové
... triethylenetetramine (TETA), which is selective CuII- chelator used in the treatment of Wilson's disease for decades. Liposomal formulations were prepared by a film hydration method with subsequent dual asymmetric centrifugation with the addition of 2.5 mol/l TETA solution dissolved at pH3 or/and pH ...
... triethylenetetramine (TETA), which is selective CuII- chelator used in the treatment of Wilson's disease for decades. Liposomal formulations were prepared by a film hydration method with subsequent dual asymmetric centrifugation with the addition of 2.5 mol/l TETA solution dissolved at pH3 or/and pH ...
Aminoglycosides
... parenteral administ. usually are subtherapeutic ( Concentration in CSF is< 10% of plasma & ↑ to 25% in meningitis and intrathecal & intraventricular administration of Amgl.s and can achieve therapeutic levels) . ...
... parenteral administ. usually are subtherapeutic ( Concentration in CSF is< 10% of plasma & ↑ to 25% in meningitis and intrathecal & intraventricular administration of Amgl.s and can achieve therapeutic levels) . ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights
... Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in susceptible children or adults using corticosteroids. In such children or adults who have not ...
... Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in susceptible children or adults using corticosteroids. In such children or adults who have not ...
Improving anti-drug antibody assay performance in
... Today mAbs are used as targeting therapies for several diseases including autoimmune and infectious diseases, oncological disorders and transplant rejection (Hansel et al. 2010). In 2012 Sloan et al. reported that over 20 mAbs have been approved and that more than 200 are in development. One advanta ...
... Today mAbs are used as targeting therapies for several diseases including autoimmune and infectious diseases, oncological disorders and transplant rejection (Hansel et al. 2010). In 2012 Sloan et al. reported that over 20 mAbs have been approved and that more than 200 are in development. One advanta ...
The ibogaine medical subculture
... Ibogaine, either as Tabernanthe iboga root bark or ibogaine HCl is the only iboga alkaloid that has reportedly been administered to humans, with apparently only one exception, a study in which 12 normal volunteers were evaluated with some brief neuropsychological tests after receiving the naturally ...
... Ibogaine, either as Tabernanthe iboga root bark or ibogaine HCl is the only iboga alkaloid that has reportedly been administered to humans, with apparently only one exception, a study in which 12 normal volunteers were evaluated with some brief neuropsychological tests after receiving the naturally ...
Guidelines of care for acne vulgaris management
... questions to structure the primary issues in diagnosis and management. Work group members were asked to complete a disclosure of commercial support, and this information will be in the acne technical report available on www.aad.org. An evidence-based model was used and some evidence was obtained by ...
... questions to structure the primary issues in diagnosis and management. Work group members were asked to complete a disclosure of commercial support, and this information will be in the acne technical report available on www.aad.org. An evidence-based model was used and some evidence was obtained by ...
Concentrate! Key Takeaways of new insulin products
... In the Inpatient Setting: • Insulin pens are preferred by nurses Felt it was easier to teach patients to self-administer insulin using a pen device • Felt that the risk of a dosing error was lower with a pen device vs. syringe ...
... In the Inpatient Setting: • Insulin pens are preferred by nurses Felt it was easier to teach patients to self-administer insulin using a pen device • Felt that the risk of a dosing error was lower with a pen device vs. syringe ...
pdf 53Kb - NSW Bureau of Crime Statistics and Research
... men.3 The weekly doses of 600mg were six times greater than the doses usually given to men to treat hypogonadism, and are the highest administered for any study of athletic performance. After 10 weeks, subjects in the experimental group averaged an increase of 6.1 kg of fat free muscle mass. Some re ...
... men.3 The weekly doses of 600mg were six times greater than the doses usually given to men to treat hypogonadism, and are the highest administered for any study of athletic performance. After 10 weeks, subjects in the experimental group averaged an increase of 6.1 kg of fat free muscle mass. Some re ...
Breining Institute
... reports “methamphetamine is the fastest growing drug threat and the most prevalent synthetic drug manufactured in the United States.” According to the 2000 National Household Survey on Drug Abuse, an estimated 8.8 million people, approximately four percent of the population, has tried methamphetamin ...
... reports “methamphetamine is the fastest growing drug threat and the most prevalent synthetic drug manufactured in the United States.” According to the 2000 National Household Survey on Drug Abuse, an estimated 8.8 million people, approximately four percent of the population, has tried methamphetamin ...
ranitidine oral
... The manufacturers state that increased or decreased prothrombin time (PT) has been reported during concomitant therapy with ranitidine and warfarin; however, pharmacokinetic studies of ranitidine at dosages of up to 400 mg daily and warfarin demonstrated no effect on warfarin clearance and/or PT. Ra ...
... The manufacturers state that increased or decreased prothrombin time (PT) has been reported during concomitant therapy with ranitidine and warfarin; however, pharmacokinetic studies of ranitidine at dosages of up to 400 mg daily and warfarin demonstrated no effect on warfarin clearance and/or PT. Ra ...
SCIENTIFIC DISCUSSION
... recognise many epileptic diseases or syndromes and each of them can be expressed clinically by one or several seizure groupings. Partial epilepsies (localisation related) are the more frequent, accounting for more than 60% of the epilepsies, and they include most of the difficult-to-treat patients. ...
... recognise many epileptic diseases or syndromes and each of them can be expressed clinically by one or several seizure groupings. Partial epilepsies (localisation related) are the more frequent, accounting for more than 60% of the epilepsies, and they include most of the difficult-to-treat patients. ...
Blind copy - Open Journal Systems
... convenient to support the conclusions on additional techniques. The compatibility study between efavirenz and excipients, some of them already reported using only DSC as well with other excipients that have not been reported, was conducted. Efavirenz is a nonnucleoside reverse transcriptase inhibito ...
... convenient to support the conclusions on additional techniques. The compatibility study between efavirenz and excipients, some of them already reported using only DSC as well with other excipients that have not been reported, was conducted. Efavirenz is a nonnucleoside reverse transcriptase inhibito ...
Public Assessment Report Decentralised Procedure Levofloxacin 250 mg and 500 mg Film-coated
... Tablets, may be symptomatic of Clostridium difficile-associated disease, the most severe form of which is pseudomembranous enterocolitis. If pseudomembranous enterocolitis is suspected, Levofloxacin Tablets must be stopped immediately and patients should be treated with supportive measures and speci ...
... Tablets, may be symptomatic of Clostridium difficile-associated disease, the most severe form of which is pseudomembranous enterocolitis. If pseudomembranous enterocolitis is suspected, Levofloxacin Tablets must be stopped immediately and patients should be treated with supportive measures and speci ...
advanced sedation techniques
... dentistry is fairly poor in its access and availability. S Need for such services is indisputable. S Due to the severe burden on the NHS hospital sector and the high ...
... dentistry is fairly poor in its access and availability. S Need for such services is indisputable. S Due to the severe burden on the NHS hospital sector and the high ...
effect of piperine, a major component of black pepper, on the
... plasma concentration (Cmax) and the elimination half-life (t1/2) of domperidone were significantly higher than those obtained in animals that were given domperidone alone(P<0.05, Table 1). The time needed to reach Cmax (Tmax), however, was not changed. The intraperitoneal pharmacokinetics of domperi ...
... plasma concentration (Cmax) and the elimination half-life (t1/2) of domperidone were significantly higher than those obtained in animals that were given domperidone alone(P<0.05, Table 1). The time needed to reach Cmax (Tmax), however, was not changed. The intraperitoneal pharmacokinetics of domperi ...
Ropinirole 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg and 5 mg
... exhibits a large volume of distribution (approx. 8 l/kg) and is cleared from the systemic circulation with an average elimination half-life of about six hours. Plasma ...
... exhibits a large volume of distribution (approx. 8 l/kg) and is cleared from the systemic circulation with an average elimination half-life of about six hours. Plasma ...
Extract from Clinical Evaluation Report: Ivermectin
... common due to the high prevalence of scabies, overcrowding and frequent movement between households and communities. Another potential concern is the development of drug resistance when such long-running community disease control programs achieve only limited participation and disease reduction. Con ...
... common due to the high prevalence of scabies, overcrowding and frequent movement between households and communities. Another potential concern is the development of drug resistance when such long-running community disease control programs achieve only limited participation and disease reduction. Con ...
DOXOrubicin vials - Sagent Pharmaceuticals
... Doxorubicin HCl can result in myocardial damage, including acute left ventricular failure. The risk of cardiomyopathy is generally proportional to the cumulative exposure. Include prior doses of other anthracyclines or anthracenediones in calculations of total cumulative dosage for doxorubicin HCl. ...
... Doxorubicin HCl can result in myocardial damage, including acute left ventricular failure. The risk of cardiomyopathy is generally proportional to the cumulative exposure. Include prior doses of other anthracyclines or anthracenediones in calculations of total cumulative dosage for doxorubicin HCl. ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.