AMERICAN ACADEMY OF PEDIATRICS Adolescents and Anabolic
... about the benefits and risks of using anabolic steroids. There is a clear need for input that is objective, rational, nonbiased, and readily available to the adolescent. If pediatricians and other pediatric health care advocates are to serve as a much needed “voice of reason,” they must be familiar ...
... about the benefits and risks of using anabolic steroids. There is a clear need for input that is objective, rational, nonbiased, and readily available to the adolescent. If pediatricians and other pediatric health care advocates are to serve as a much needed “voice of reason,” they must be familiar ...
Extended-Release Tablets, USP (SR)
... The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder (OCD), or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over 4,400 subjects. The pooled analyses of placebo-controlled trials in ad ...
... The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder (OCD), or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over 4,400 subjects. The pooled analyses of placebo-controlled trials in ad ...
KEY and EXPLANATION for SET-A
... Schedule W says about list of drugs to be marketed under generic names only. Hence, option C is CORRECT answer. Schedule J: Names of diseases and ailments (by whatever name described) which a drug may not purpose to prevent or cure by means of claims made on the label of the container of the drug. S ...
... Schedule W says about list of drugs to be marketed under generic names only. Hence, option C is CORRECT answer. Schedule J: Names of diseases and ailments (by whatever name described) which a drug may not purpose to prevent or cure by means of claims made on the label of the container of the drug. S ...
Use of Codeine in Children
... Safety concerns with codeine There have been growing safety concerns of codeine toxicity in ultra-rapid metabolizers o Ultra-rapid metabolizers convert codeine to morphine more rapidly and completely than the general population. They have plasma levels of morphine 50% higher than normal, leading t ...
... Safety concerns with codeine There have been growing safety concerns of codeine toxicity in ultra-rapid metabolizers o Ultra-rapid metabolizers convert codeine to morphine more rapidly and completely than the general population. They have plasma levels of morphine 50% higher than normal, leading t ...
Ulipristal acetate - Therapeutic Goods Administration
... This work is copyright. You may reproduce the whole or part of this work in unaltered form for your own personal use or, if you are part of an organisation, for internal use within your organisation, but only if you or your organisation do not use the reproduction for any commercial purpose and reta ...
... This work is copyright. You may reproduce the whole or part of this work in unaltered form for your own personal use or, if you are part of an organisation, for internal use within your organisation, but only if you or your organisation do not use the reproduction for any commercial purpose and reta ...
British Association for Psychopharmacology consensus statement
... Diagnostic criteria). They all agree insomnia is a condition of unsatisfactory sleep, either in terms of sleep onset, sleep maintenance or early waking. They also agree that insomnia is a disorder that impairs daytime well-being and subjective abilities and functioning, and so can be considered a ‘2 ...
... Diagnostic criteria). They all agree insomnia is a condition of unsatisfactory sleep, either in terms of sleep onset, sleep maintenance or early waking. They also agree that insomnia is a disorder that impairs daytime well-being and subjective abilities and functioning, and so can be considered a ‘2 ...
drug registration guidance document (drgd) - NPRA
... Homeopathic medicines: Any medicine prepared in accordance with a homeopathic manufacturing procedure described by a pharmacopoeia in official use or other officially recognized documents. A homeopathic medicine may contain a number of homeopathic preparations. Homeopathy: Classical homeopathy is a ...
... Homeopathic medicines: Any medicine prepared in accordance with a homeopathic manufacturing procedure described by a pharmacopoeia in official use or other officially recognized documents. A homeopathic medicine may contain a number of homeopathic preparations. Homeopathy: Classical homeopathy is a ...
... aminoglycoside antibiotics,colistin, polymyxin and viomycin) and strongacting diuretics (e.g. ethacrynic acid or furosemide) induce an increased risk of impairment of renal function (see section 4.4). Nifedipine, a calcium channel blocker, may increase bioavailability of cefixime up to 70 %. In comm ...
Actinomycosis: etiology, clinical features, diagnosis, treatment, and management Infection and Drug Resistance Dove
... Abstract: Actinomycosis is a rare chronic disease caused by Actinomyces spp., anaerobic Gram-positive bacteria that normally colonize the human mouth and digestive and genital tracts. Physicians must be aware of typical clinical presentations (such as cervicofacial actinomycosis following dental foc ...
... Abstract: Actinomycosis is a rare chronic disease caused by Actinomyces spp., anaerobic Gram-positive bacteria that normally colonize the human mouth and digestive and genital tracts. Physicians must be aware of typical clinical presentations (such as cervicofacial actinomycosis following dental foc ...
Review articles Treatment of Myoclonus
... at least one treatment. Levetiracetam was administered from 500 to 2,000 mg per day, over a period from four weeks to eleven months. Levetiracetam was well tolerated in all cases, except in two patients who had to stop treatment because of sedation. Three patients felt dramatic improvement within th ...
... at least one treatment. Levetiracetam was administered from 500 to 2,000 mg per day, over a period from four weeks to eleven months. Levetiracetam was well tolerated in all cases, except in two patients who had to stop treatment because of sedation. Three patients felt dramatic improvement within th ...
Nasal Drug Delivery
... Drugs have been administered nasally for therapeutic and recreational purposes since ancient times. Psychotropic drugs and hallucinogens were snuffed for these purposes by the Indians of South America, and this practice is currently widespread among abusers of cocaine and heroin (Chien and Chang, 19 ...
... Drugs have been administered nasally for therapeutic and recreational purposes since ancient times. Psychotropic drugs and hallucinogens were snuffed for these purposes by the Indians of South America, and this practice is currently widespread among abusers of cocaine and heroin (Chien and Chang, 19 ...
Losartan Potassium
... ER. Published evidence for the efficacy of losartan potassium in other special patient groups is scant, as are long term efficacy data. Results from double-blind trials involving a total of >2800 patients with hypertension who received losartan potassium indicate that the drug is very well tolerated ...
... ER. Published evidence for the efficacy of losartan potassium in other special patient groups is scant, as are long term efficacy data. Results from double-blind trials involving a total of >2800 patients with hypertension who received losartan potassium indicate that the drug is very well tolerated ...
Central Nervous System Permeation of Non
... Every year 5-10% of children undergo anaesthesia and surgery in Europe. Orthopaedic, gastrointestinal and oto-rhino-laryngological procedures are the most common operations in children (Clergue et al. 1999). Surgical procedures, anaesthesia and postoperative pain have a significant impact on the wel ...
... Every year 5-10% of children undergo anaesthesia and surgery in Europe. Orthopaedic, gastrointestinal and oto-rhino-laryngological procedures are the most common operations in children (Clergue et al. 1999). Surgical procedures, anaesthesia and postoperative pain have a significant impact on the wel ...
Alaris® PK Syringe Pump
... For anaesthetic agents the effect-site (or bio-phase) is not the plasma4 but the brain, where concentrations cannot be directly measured. Until the early 1990’s it was considered that blood-brain equilibration was virtually instantaneous. Early TCI systems were thus all plasma-targeted. For many dru ...
... For anaesthetic agents the effect-site (or bio-phase) is not the plasma4 but the brain, where concentrations cannot be directly measured. Until the early 1990’s it was considered that blood-brain equilibration was virtually instantaneous. Early TCI systems were thus all plasma-targeted. For many dru ...
Cannabis - Mister Gui
... There are many claims regarding the use of cannabis in a medical context, both pro and con. [5][6] On April 20, 2006 the United States Food and Drug Administration (FDA) issued an intra-agency advisory warning against medical cannabis, restating the Drug Enforcement Administration's position that ma ...
... There are many claims regarding the use of cannabis in a medical context, both pro and con. [5][6] On April 20, 2006 the United States Food and Drug Administration (FDA) issued an intra-agency advisory warning against medical cannabis, restating the Drug Enforcement Administration's position that ma ...
Ribavirin - Hepatitis C Online
... ribavirin is available in an oral (liquid) solution. The availability of specific strength depends on the brand of the ribavirin. Ribavirin (Copegus) is available in 200 mg tablets (Figure 2) and should be taken with food. The daily dose when given as fixed dosing is 800 mg per day in two divided do ...
... ribavirin is available in an oral (liquid) solution. The availability of specific strength depends on the brand of the ribavirin. Ribavirin (Copegus) is available in 200 mg tablets (Figure 2) and should be taken with food. The daily dose when given as fixed dosing is 800 mg per day in two divided do ...
Gelsemium sempervirens - Southwest School of Botanical Medicine
... made the therapeutical reputation of the drug. If the drying process did not break the natural interstructural combination, the heroic chemistry used in splitting it into fragments would accomplish that result. These alkaloids and other products are obtained from Gelsemium, but we neither comprehend ...
... made the therapeutical reputation of the drug. If the drying process did not break the natural interstructural combination, the heroic chemistry used in splitting it into fragments would accomplish that result. These alkaloids and other products are obtained from Gelsemium, but we neither comprehend ...
Zebrafish as tools for drug discovery
... events and functional redundancy have hampered comprehensive study of the conservation of the metabolic processing of small molecules8,36. The conservation of other drug metabolism pathways is only beginning to be explored, but to date there is evidence of substantial functional parallels across div ...
... events and functional redundancy have hampered comprehensive study of the conservation of the metabolic processing of small molecules8,36. The conservation of other drug metabolism pathways is only beginning to be explored, but to date there is evidence of substantial functional parallels across div ...
Lemon Balm - Longwood Herbal Task Force
... i. In vitro data: Rosmarinic acid has inhibitory effects on both the classical pathway convertase and the alternative pathway convertase. It inhibited 70% of the immunohemolysis of antibody-coated sheep erythrocytes by guinea pig serum via possible inhibition of the C3-convertase of the classical co ...
... i. In vitro data: Rosmarinic acid has inhibitory effects on both the classical pathway convertase and the alternative pathway convertase. It inhibited 70% of the immunohemolysis of antibody-coated sheep erythrocytes by guinea pig serum via possible inhibition of the C3-convertase of the classical co ...
ION - Boston Scientific
... Contents supplied STERILE using an ethylene oxide (EO) process. Do not use if sterile barrier is damaged. If damage is found, call your Boston Scientific representative. For single use only. Do not reuse, reprocess or resterilize. Reuse, reprocessing or resterilization may compromise the structural ...
... Contents supplied STERILE using an ethylene oxide (EO) process. Do not use if sterile barrier is damaged. If damage is found, call your Boston Scientific representative. For single use only. Do not reuse, reprocess or resterilize. Reuse, reprocessing or resterilization may compromise the structural ...
5 1 Prereview - World Health Organization
... limited in preclinical and clinical studies, lisdexamfetamine does produce similar subjective and discriminative effects as d-amphetamine in humans and animals, respectively. The observation that lisdexamfetamine produces substantial and sustained increases in catecholaminergic neurotransmission in ...
... limited in preclinical and clinical studies, lisdexamfetamine does produce similar subjective and discriminative effects as d-amphetamine in humans and animals, respectively. The observation that lisdexamfetamine produces substantial and sustained increases in catecholaminergic neurotransmission in ...
NovoRapid® - Product Monograph Page 1 of 50 PRODUCT
... NovoRapid group and were not different from the human insulin group. No adverse effects could be attributed to patients producing cross-reactive antibodies as compared to those who did not. There was no correlation between the extent of antibody formation and the insulin dose needed, level of glycem ...
... NovoRapid group and were not different from the human insulin group. No adverse effects could be attributed to patients producing cross-reactive antibodies as compared to those who did not. There was no correlation between the extent of antibody formation and the insulin dose needed, level of glycem ...
List of abbreviations - Therapeutic Goods Administration
... include sections from the CER regarding product documentation or post market activities. ...
... include sections from the CER regarding product documentation or post market activities. ...
ENCLOSURE 1
... Wheal and Flare: Human histamine skin wheal and flare studies following single and twice daily doses of 20 and 40 mg fexofenadine hydrochloride demonstrated that the drug exhibits an antihistamine effect by l hour, achieves maximum effect at 2 to 3 hours, and an effect is still seen at 12 hours. The ...
... Wheal and Flare: Human histamine skin wheal and flare studies following single and twice daily doses of 20 and 40 mg fexofenadine hydrochloride demonstrated that the drug exhibits an antihistamine effect by l hour, achieves maximum effect at 2 to 3 hours, and an effect is still seen at 12 hours. The ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.