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Life Cycle of a Virus
Life Cycle of a Virus

... ...
Infection control in Hospital
Infection control in Hospital

... What is infection? ...
CMV Mononucleosis
CMV Mononucleosis

... syndrome in normal host • Congenital CMV syndrome frequently fatal • Potential for much more severe disease in immunocompromised • BMT: CMV pneumonia most common lifethreatening infection • AIDS: most common viral infection Mandell, 5th ed., 2000;1586-1596. ...
Longterm effects of CMV in the elderly
Longterm effects of CMV in the elderly

...  Routinely diagnosed by the detection of anti-CMV IgG & IgM antibodies.  Worldwide high prevalence rates between 40-100%  BELFRAIL: 74%  Omsk region: 90-95%  “Cytomegalovirus infection in Omsk region. Dolgikh et al. 2008 Zh Mikrobiol Epidemiol Immunobiol.” ...
IPC crossword quiz - South West Yorkshire Partnership NHS
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... 18 Objects that may become contaminated with microorganisms and serve as a vehicle of transmission (like a door handle or keyboard) ...
such as bacteria and viruses. Platelets
such as bacteria and viruses. Platelets

... c. Symptoms (affects) - redness, heat, swelling and pain in the specific area that the infection occurs. d. Treatment – antibiotics are effective against bacterial infections. e. Body Response i. The body’s immune system also fights infections. ii. Proteins, called antigens, on the surface of bacter ...
Epstein-Barr Virus
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Hepatitis C and the link to liver disease
Hepatitis C and the link to liver disease

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Lentivirus - The Evergreen State College
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View Full Text-PDF

Pneumonia in the Immunocompromised
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The Acute Phase Response

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Human cytomegalovirus



Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within Herpesviridae, HCMV belongs to the Betaherpesvirinae subfamily, which also includes cytomegaloviruses from other mammals.Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly other malignancies such as prostate cancer.HCMV is found throughout all geographic locations and socioeconomic groups, and infects between 60% and 70% of adults in industrialized countries and almost 100% in emerging countries.Of all herpes viruses, HCMV harbors the most genes dedicated to altering (evading) innate and adaptive immunity in the host and represents a life-long burden of antigenic T cell surveillance and immune dysfunction.Commonly it is indicated by the presence of antibodies in the general population. Seroprevalence is age-dependent: 58.9% of individuals aged 6 and older are infected with CMV while 90.8% of individuals aged 80 and older are positive for HCMV. HCMV is also the virus most frequently transmitted to a developing fetus.HCMV infection is more widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. Congenital HCMV is the leading infectious cause of deafness, learning disabilities, and intellectual disability in childrenCMV also ""seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality.""
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