Ecology
... • Ecosystem: A biological community and all of the abiotic factors that affect it. • Biome: A large group of ecosystems that share the same climate and have similar types of communities. • Biosphere: All biomes together; the Earth ...
... • Ecosystem: A biological community and all of the abiotic factors that affect it. • Biome: A large group of ecosystems that share the same climate and have similar types of communities. • Biosphere: All biomes together; the Earth ...
Nevofam - mn.com.tr
... Gastroesophageal reflux Various pathological hypersecretory conditions such as multiple endocrine adenoma CONTRAINDICATIONS: Is contraindicated in patients hypersensitive to famotidine. WARNINGS AND PRECAUTIONS: In patients with severe renal failure (creatinine clearance < 10 mL / min) lower doses o ...
... Gastroesophageal reflux Various pathological hypersecretory conditions such as multiple endocrine adenoma CONTRAINDICATIONS: Is contraindicated in patients hypersensitive to famotidine. WARNINGS AND PRECAUTIONS: In patients with severe renal failure (creatinine clearance < 10 mL / min) lower doses o ...
Powerpoint
... • INH (mycolic acid, DOC, Liver, neurotox (pyridoxine), G6PDH) • Streptomycin (see aminoglycosides) • Rifampin (DNA-dep RNA pol, red-orange fluid, renal/hep tox, p450) • Ethambutol (visual/CNS tox, red-green colorblind, use in combo) ...
... • INH (mycolic acid, DOC, Liver, neurotox (pyridoxine), G6PDH) • Streptomycin (see aminoglycosides) • Rifampin (DNA-dep RNA pol, red-orange fluid, renal/hep tox, p450) • Ethambutol (visual/CNS tox, red-green colorblind, use in combo) ...
hepatoprotective effects of aqueous extract of andrographis
... physical,biochemical changes.pretreatment with extract significantly prevented the physical ,biochemical changes 1 induced by CCL4 in the liver.The effects of andrographis paniculata could be useful in preventing chemically induced2 acute liver injury.It can be concluded that the aqueous extract ...
... physical,biochemical changes.pretreatment with extract significantly prevented the physical ,biochemical changes 1 induced by CCL4 in the liver.The effects of andrographis paniculata could be useful in preventing chemically induced2 acute liver injury.It can be concluded that the aqueous extract ...
Week 6 lecture slides
... flumazenil all work by causing stimulation which counteracts the sedation caused by ethanol. Ro 15-4513 actually prevents ethanol from binding to its molecular target. However, ethanol has many molecular targets, and Ro 15-4513 only blocks one of ...
... flumazenil all work by causing stimulation which counteracts the sedation caused by ethanol. Ro 15-4513 actually prevents ethanol from binding to its molecular target. However, ethanol has many molecular targets, and Ro 15-4513 only blocks one of ...
Carbon Monoxide poisoning
... • HCN binds to heme iron in the cytochrome oxidase (aa3) (has high affinity for Fe+++) forming a complex • This complex inhibits the final step of oxidative phosphorylation where O2 is used for the production of ATP • Aerobic metabolism stops (cells will not be able to use Q2), Patient essentially s ...
... • HCN binds to heme iron in the cytochrome oxidase (aa3) (has high affinity for Fe+++) forming a complex • This complex inhibits the final step of oxidative phosphorylation where O2 is used for the production of ATP • Aerobic metabolism stops (cells will not be able to use Q2), Patient essentially s ...
Post-operative Nausea and Vomiting - Vanderbilt University Medical
... ASPAN’s guidelines for the prevention of PONV includes in addition to medications, the following actions have evidence of decreasing/preventing PONV: • Hydration-due to NPO status and fluids lost during surgery, post-operative patients are frequently still in fluid deficits. Recommended IV fluid dos ...
... ASPAN’s guidelines for the prevention of PONV includes in addition to medications, the following actions have evidence of decreasing/preventing PONV: • Hydration-due to NPO status and fluids lost during surgery, post-operative patients are frequently still in fluid deficits. Recommended IV fluid dos ...
Neuroleptics - Univerzita Karlova v Praze
... monoamine release arise via a variety of mechanisms (monoamine oxidase inhibition, reuptake blockade, presynaptic or somatodendritic autoreceptor downregulation), and result in activation of a range of post-synaptic receptors that are coupled to ‘second messenger’ signal transduction mechanisms. Act ...
... monoamine release arise via a variety of mechanisms (monoamine oxidase inhibition, reuptake blockade, presynaptic or somatodendritic autoreceptor downregulation), and result in activation of a range of post-synaptic receptors that are coupled to ‘second messenger’ signal transduction mechanisms. Act ...
Villy Cristensen: Using ecosystem modeling for fisheries
... • Failure to anticipate new problems (‘vampires in the basement’) due to unpredictable changes in system ...
... • Failure to anticipate new problems (‘vampires in the basement’) due to unpredictable changes in system ...
No Slide Title - Open.Michigan
... { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses a ...
... { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses a ...
Drug Treatments - Osteoporosis Canada
... alone. For women who still have their uterus, estrogen is given in combination with progesterone to reduce the risk of developing uterine cancer. ...
... alone. For women who still have their uterus, estrogen is given in combination with progesterone to reduce the risk of developing uterine cancer. ...
Chapter 16 Cholinesterase Inhibitors
... Mechanism of action • Selective blockade of aldosterone receptors Therapeutic uses • Hypertension • Heart failure Pharmacokinetics • Absorption is not affected by food Adverse effects • Hyperkalemia ...
... Mechanism of action • Selective blockade of aldosterone receptors Therapeutic uses • Hypertension • Heart failure Pharmacokinetics • Absorption is not affected by food Adverse effects • Hyperkalemia ...
Elicited Behavior and Classical Conditioning
... they interact with receptors on target tissues. Drugs or ligands that bind and are capable of changing the shape of the receptor protein and subsequently alter cell function are called agonists. The ligands that attach most readily are said to have high affinity for the receptor. Antagonists, in con ...
... they interact with receptors on target tissues. Drugs or ligands that bind and are capable of changing the shape of the receptor protein and subsequently alter cell function are called agonists. The ligands that attach most readily are said to have high affinity for the receptor. Antagonists, in con ...
Successes, Threats, Challenges and Opportunities of Early
... • Safety Pharmacology Departments in AstraZeneca, in particular all the Team Leaders / Head of Departments: ...
... • Safety Pharmacology Departments in AstraZeneca, in particular all the Team Leaders / Head of Departments: ...
Adverse reactions
... the mechanism of action of antipsychotic drugs: 1) Mesolimbic-mesocortical pathway: the one most closely related to behavior and psychosis 2) Nigrostriatal pathway: it is involved in the coordination of voluntary movement. Blockade of the D2 receptors in the nigrostriatal pathway is responsible for ...
... the mechanism of action of antipsychotic drugs: 1) Mesolimbic-mesocortical pathway: the one most closely related to behavior and psychosis 2) Nigrostriatal pathway: it is involved in the coordination of voluntary movement. Blockade of the D2 receptors in the nigrostriatal pathway is responsible for ...
Cocaine & Amphetamines
... In the presence of ethanol a different metabolite is produced – cocaethylene Cocaethylene has the same physiological effect on the brain as cocaine but more toxic ...
... In the presence of ethanol a different metabolite is produced – cocaethylene Cocaethylene has the same physiological effect on the brain as cocaine but more toxic ...
Replacement of a Thiourea-S with an Amidine
... effect of sulfur. In their pioneering studies of the inorganic kinetic cis-effect, Tobe and co-workers demonstrated for the complexes [PtCl(en)(dmso-S)]+ and [PtCl(en)(dms)]+ (dmso ) dimethylsulfoxide, dms ) dimethylsulfide) that the sulfur donors greatly accelerate chloride substitution by an incom ...
... effect of sulfur. In their pioneering studies of the inorganic kinetic cis-effect, Tobe and co-workers demonstrated for the complexes [PtCl(en)(dmso-S)]+ and [PtCl(en)(dms)]+ (dmso ) dimethylsulfoxide, dms ) dimethylsulfide) that the sulfur donors greatly accelerate chloride substitution by an incom ...
Adverse reactions
... the mechanism of action of antipsychotic drugs: 1) Mesolimbic-mesocortical pathway: the one most closely related to behavior and psychosis 2) Nigrostriatal pathway: it is involved in the coordination of voluntary movement. Blockade of the D2 receptors in the nigrostriatal pathway is responsible for ...
... the mechanism of action of antipsychotic drugs: 1) Mesolimbic-mesocortical pathway: the one most closely related to behavior and psychosis 2) Nigrostriatal pathway: it is involved in the coordination of voluntary movement. Blockade of the D2 receptors in the nigrostriatal pathway is responsible for ...
4.Geetha T. S and Geetha N - International Journal of Pharmacy and
... Cancer is a major cause of death and breast cancer is one of the common malignancies and leading causes of cancer death in women around the world. Breast cancer is a malignant tumor that starts in the cells of the breast. A malignant tumor is a group of cancer cells that can grow into (invade) surro ...
... Cancer is a major cause of death and breast cancer is one of the common malignancies and leading causes of cancer death in women around the world. Breast cancer is a malignant tumor that starts in the cells of the breast. A malignant tumor is a group of cancer cells that can grow into (invade) surro ...
Sedation & Analgesia - Pediatric Critical Care Education
... GABA agonist—binds alpha subunit Sedative only, no analgesic effects Rapid onset and offset and no withdrawal Onset: within 30 seconds Duration: 3-10 minutes but depends on duration of infusion PK follows 3 compartment model – Rapid distribution from blood into tissues – Rapid metabolic clearance fr ...
... GABA agonist—binds alpha subunit Sedative only, no analgesic effects Rapid onset and offset and no withdrawal Onset: within 30 seconds Duration: 3-10 minutes but depends on duration of infusion PK follows 3 compartment model – Rapid distribution from blood into tissues – Rapid metabolic clearance fr ...
Lecture presentation - TMA Department Sites
... Stimulation of beta2-adrenergic receptors on the airways results in: • Bronchodilation (relaxation of the bronchi) • Uterine relaxation • Glycogenolysis in the liver ...
... Stimulation of beta2-adrenergic receptors on the airways results in: • Bronchodilation (relaxation of the bronchi) • Uterine relaxation • Glycogenolysis in the liver ...
Where Have All the FISH Gone?
... Estrogen disrupters are also chemicals of concern. These so-called environmental hormones have been found in WWTP effluents at concentrations that affect trout (7). Effluents throughout Switzerland contain the naturally occurring steroid hormones estrone, estradiol, and estriol; the synthetic ethiny ...
... Estrogen disrupters are also chemicals of concern. These so-called environmental hormones have been found in WWTP effluents at concentrations that affect trout (7). Effluents throughout Switzerland contain the naturally occurring steroid hormones estrone, estradiol, and estriol; the synthetic ethiny ...
Homeostasis and the envrionment
... regulates our bodies (removal of nitrogenous waste, immune system). • While these are good examples of homeostasis, they are at an organism or cellular level. • We can also see examples of homeostasis at higher levels such as populations, communities and ecosystems. • The purpose of this exercise to ...
... regulates our bodies (removal of nitrogenous waste, immune system). • While these are good examples of homeostasis, they are at an organism or cellular level. • We can also see examples of homeostasis at higher levels such as populations, communities and ecosystems. • The purpose of this exercise to ...
Antipsychotics
... Tardive dyskinesia (TD) TD is a latent extrapyramidal effect generally not occurring for months or years, occur in 20% patient treated with antipsychotic. It is characterized by abnormal movements that can occur in any part of the body, including faces, tongue, shoulders, hips, extremities, finge ...
... Tardive dyskinesia (TD) TD is a latent extrapyramidal effect generally not occurring for months or years, occur in 20% patient treated with antipsychotic. It is characterized by abnormal movements that can occur in any part of the body, including faces, tongue, shoulders, hips, extremities, finge ...
Toxicodynamics
Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.