Ch 2 m definitions
... only eats plants 13. Heterotroph – organism that eats to get energy 14. Omnivore - organism that eats both plants/animals 15. Biogeochemical cycle – a series of physical and biological processes by which nutrients are cycled through the ...
... only eats plants 13. Heterotroph – organism that eats to get energy 14. Omnivore - organism that eats both plants/animals 15. Biogeochemical cycle – a series of physical and biological processes by which nutrients are cycled through the ...
Definitions
... Combines indicators, or metrics, into a single index value. Each metric is tested and calibrated to a scale and transformed into a unit-less score prior to being aggregated into a multi-metric index. Both the index, and metrics, are useful in assessing and diagnosing ecological condition. ...
... Combines indicators, or metrics, into a single index value. Each metric is tested and calibrated to a scale and transformed into a unit-less score prior to being aggregated into a multi-metric index. Both the index, and metrics, are useful in assessing and diagnosing ecological condition. ...
chapter 4 psychopharmacology
... – Must be synthesized within the neuron – In response to an action potential, the substance is released in sufficient quantities to produce an effect in the postsynaptic cell – We should be able to duplicate the action of a suspected neurotransmitter experimentally on a postsynaptic cell – Some mech ...
... – Must be synthesized within the neuron – In response to an action potential, the substance is released in sufficient quantities to produce an effect in the postsynaptic cell – We should be able to duplicate the action of a suspected neurotransmitter experimentally on a postsynaptic cell – Some mech ...
Opioids – anal-gesics (lol) ©2010 Mark Tuttle Mechanism of action
... - Morphine can release histamine from mast cells - Naltrexone (Oral) - Miosis, dysphoria, psychotic o Acute/chronic withdr. - Gastrointestinal Tract (myenteric plexus): Will precipitate abstinence (withdrawal) δ , Σ receptors o Longer t½ o ↑ tone, ↓peristalsis: constipation syndrome if addict is not ...
... - Morphine can release histamine from mast cells - Naltrexone (Oral) - Miosis, dysphoria, psychotic o Acute/chronic withdr. - Gastrointestinal Tract (myenteric plexus): Will precipitate abstinence (withdrawal) δ , Σ receptors o Longer t½ o ↑ tone, ↓peristalsis: constipation syndrome if addict is not ...
2- H1 and H2 Receptors
... positive chronotropism (mediated by H2 receptors) and a positive inotropism (mediated by both H1 and H2 receptors). Skin Dilation and increased permeability of the capillaries results in leakage of proteins and fluid into the tissues. In the skin, this results in the classic “triple response”: wheal ...
... positive chronotropism (mediated by H2 receptors) and a positive inotropism (mediated by both H1 and H2 receptors). Skin Dilation and increased permeability of the capillaries results in leakage of proteins and fluid into the tissues. In the skin, this results in the classic “triple response”: wheal ...
File - Wk 1-2
... several days fro recovery) Receptors are taken into cell be endocytosis and also depends on receptor phosphorylation Common for hormone receptors Exhaustion of mediators Desensitisation can be associated with depletion of an intermediate substance (rarer) Increased metabolic degradation of the ...
... several days fro recovery) Receptors are taken into cell be endocytosis and also depends on receptor phosphorylation Common for hormone receptors Exhaustion of mediators Desensitisation can be associated with depletion of an intermediate substance (rarer) Increased metabolic degradation of the ...
I. The direct-acting drugs
... open-angle glaucoma some cases of secondary glaucoma Postoperative ileus: Stomach, bowel, urine retention: (bethanechol) Salivary secretion: (pilocaine) ...
... open-angle glaucoma some cases of secondary glaucoma Postoperative ileus: Stomach, bowel, urine retention: (bethanechol) Salivary secretion: (pilocaine) ...
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... o Cut Down – do you ever feel you should cut down on your drinking? o Annoyed – have people ever annoyed you by criticizing how much you drink? o Guilt – have you ever felt guilty about how much you drink? o Eyeopener – have you ever had a drink first thing in the morning for steady nerves/hangover? ...
... o Cut Down – do you ever feel you should cut down on your drinking? o Annoyed – have people ever annoyed you by criticizing how much you drink? o Guilt – have you ever felt guilty about how much you drink? o Eyeopener – have you ever had a drink first thing in the morning for steady nerves/hangover? ...
DRUG A - University of Kentucky
... – Striatal dopamine release and reuptake – SSRI’s and other antidepressants – Anit-anxiety medications – Anesthetics – Seizure medications – Drug Abuse ...
... – Striatal dopamine release and reuptake – SSRI’s and other antidepressants – Anit-anxiety medications – Anesthetics – Seizure medications – Drug Abuse ...
Site-of-Action (SoA) Models to Predict Tissue Target Coverage in
... ² Modeled as a posi8ve feedback loop ...
... ² Modeled as a posi8ve feedback loop ...
Organovo Investor Presentation
... High failure rates in clinical trials due to failure to predict efficacy Many areas where animal models are known to be poor predictors ...
... High failure rates in clinical trials due to failure to predict efficacy Many areas where animal models are known to be poor predictors ...
Drugs of Abuse II - London Metropolitan University
... Piomelli, D. et al. (2000) The endocannabinoid system as a target for therapeutic drugs. Trends in Pharmacological Sciences. 21: 218-224 DA: Spanagal and Weis (1999) The dopamine hypothesis of reward: past and current research. Trends in Neurosci. 22: 521-527 ...
... Piomelli, D. et al. (2000) The endocannabinoid system as a target for therapeutic drugs. Trends in Pharmacological Sciences. 21: 218-224 DA: Spanagal and Weis (1999) The dopamine hypothesis of reward: past and current research. Trends in Neurosci. 22: 521-527 ...
local anesthetics - Website of Neelay Gandhi
... -Long AP duration favors access of LA’s to receptors; BUPIVACAINE = hi risk of cardiotoxicity Blood: -Prilocaine: promotes hemoglobin-methemoglobin transformation Allergies: -ester type LA’s are metabolized to PABA = allergin ...
... -Long AP duration favors access of LA’s to receptors; BUPIVACAINE = hi risk of cardiotoxicity Blood: -Prilocaine: promotes hemoglobin-methemoglobin transformation Allergies: -ester type LA’s are metabolized to PABA = allergin ...
a homogenous flow cytometric method for the combined
... The pharmacological characterization of ligands acting on G-protein coupled receptors (GPCRs) requires the determination of both affinity and activity. The combination of binding assay and functional test using the same measurement setup would considerably facilitate the process of drug evaluation. ...
... The pharmacological characterization of ligands acting on G-protein coupled receptors (GPCRs) requires the determination of both affinity and activity. The combination of binding assay and functional test using the same measurement setup would considerably facilitate the process of drug evaluation. ...
Pharmacodynamics
... Trisphosphate •Calcium more widely used than cAMP •used in neurotransmitters, growth factors, some hormones ...
... Trisphosphate •Calcium more widely used than cAMP •used in neurotransmitters, growth factors, some hormones ...
PSYC 342: Psychopharmacology
... A small sample of Next Gens • Search to produce clozapine-like drug without agranulocytosis • Prototype: Risperidone (Risperdal) – Dual action – block D2 and 5-HT2 receptors – Other 5-HT/D2 combos ...
... A small sample of Next Gens • Search to produce clozapine-like drug without agranulocytosis • Prototype: Risperidone (Risperdal) – Dual action – block D2 and 5-HT2 receptors – Other 5-HT/D2 combos ...
(zolpidem CR) Fact Sheet - The Main Line Center for the Family
... • Does not alter normal sleep stages. • Anecdotal: uncommonly, can cause black outs (loss of memory of activities) soon after ingested if the patient does not go right to sleep. • Classified as a Schedule IV drug, but abuse potential is likely somewhat less than BZs. • Pregnancy Category C Drug-drug ...
... • Does not alter normal sleep stages. • Anecdotal: uncommonly, can cause black outs (loss of memory of activities) soon after ingested if the patient does not go right to sleep. • Classified as a Schedule IV drug, but abuse potential is likely somewhat less than BZs. • Pregnancy Category C Drug-drug ...
vocabulary ecology
... Trophic Level: The position of an organism in relation to the flow of energy and inorganic nutrients through an ecosystem (e.g., producer, consumer, and decomposer). ...
... Trophic Level: The position of an organism in relation to the flow of energy and inorganic nutrients through an ecosystem (e.g., producer, consumer, and decomposer). ...
Chapter 11 Lesson 1
... Effects of Drinking • How fast person drinks – Gulping down a drink raises the alcohol level in the blood because body has less time to process it • Other substances in the body – Drinking while using other drugs may be fatal or have severe effects ...
... Effects of Drinking • How fast person drinks – Gulping down a drink raises the alcohol level in the blood because body has less time to process it • Other substances in the body – Drinking while using other drugs may be fatal or have severe effects ...
22-3 Interactions fill
... What is your niche: at home?_______________________________ at school?_______________________________ at practice? _____________________________ Types of interactions __________________ __________________ __________________ Competition __________________________________________________ ...
... What is your niche: at home?_______________________________ at school?_______________________________ at practice? _____________________________ Types of interactions __________________ __________________ __________________ Competition __________________________________________________ ...
Time to model all life on Earth - Department of Mathematics and
... different models could be used to predict an ecosystem property that has been measured but not reported, allowing the models to be ranked in terms of how well they do. We are not proposing that GEM predictions (which will always be simplistic) provide the only guide to conservation policy and the ma ...
... different models could be used to predict an ecosystem property that has been measured but not reported, allowing the models to be ranked in terms of how well they do. We are not proposing that GEM predictions (which will always be simplistic) provide the only guide to conservation policy and the ma ...
Toxicodynamics
Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.