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Effects of cytochalasin B on meiosis and development of fertilized
Effects of cytochalasin B on meiosis and development of fertilized

... rapidly or degenerates into cytoplasmic blebbing. As a result, the two sets of dyads remained in the egg cytoplasm. As in normal development, there is no pronucleus formation at this stage. With higher concentrations, ranging from 5 to 20 ^g/ml, anaphase of first maturation division does not take pl ...
Lampbrush Chromosomes of the Chicken
Lampbrush Chromosomes of the Chicken

... relatively little about the function(s) of these meiotic chromosomes, particularly with respect to the nature of the transcribed sequences and the control of their expression. Almost all that we do know about their organization and activity comes from investigations of newt and salamander LBC where ...
Forespore membrane assembly in yeast
Forespore membrane assembly in yeast

... and target membranes carry v-SNAREs and t-SNAREs, respectively. The specific interaction between v- and tSNAREs might facilitate both docking and fusion steps. The SNARE proteins have been identified as essential components for membrane trafficking: synaptobrevin family proteins as vSNAREs, and synt ...
© NCERT not to be republished
© NCERT not to be republished

... When the F1 individuals are crossed together to raise the F2 generation, each F1 individual produces two types of gametes: 50% having dominant allele, and the remaining 50% having recessive allele. These gametes undergo random fusion during fertilisation to produce the F2 generation. According to si ...
Lac A
Lac A

... CIS dominant mutation: it expresses the dominant phenotype but it affects only the expression of genes on the same DNA molecule where the mutation occurs. LacOc, affects only neighbouring genes (plasmid) We construct an heterozygote with: The mutation lacZ- located in cis to lacOc (no production of ...
Further manipulation by centric misdivision of the 1RS.1BL
Further manipulation by centric misdivision of the 1RS.1BL

... The experiments with repeated centric fissionfusion cycles demonstrate that chromosome arms can be transferred from one translocation to another until the most suitable location is found. As a result of the manipulations described here, translocations of the same rye chromosome arm 1RS to all three ...
PPT File
PPT File

... – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated chromosomes – At anaphase I, it is homologous chromosomes, instead of sister chromatids, ...
CDK11p58 kinase activity is required to protect sister chromatid
CDK11p58 kinase activity is required to protect sister chromatid

... cancer. Premature sister chromatid separation may result from different causes, the most obvious of which being unscheduled mitosis exit. We assessed whether CDK11-depleted cells displaying PSCS had exit mitosis and found that separated sister chromatids were positive for the widely used mitotic mar ...
Secured cutting: controlling separase at the metaphase to anaphase
Secured cutting: controlling separase at the metaphase to anaphase

... Is cleavage of cohesin sufficient to trigger anaphase? If true, any protease capable of cleaving cohesin should be able to do so. This has been tested in budding yeast. One of the two separase cleavage sites in Scc1 was replaced by the specific recognition sequence of a plant virus protease. Cleavag ...
Genetic Detection of Chromosomal Interchanges
Genetic Detection of Chromosomal Interchanges

... Interchanges are those structural changes in chromosome where terminal segments of nonhomologous chromosomes have exchanged positions. These changes are also called reciprocal translations. Interchanges in plants are usually associated with semi sterility of gametes. Although in exceptional cases in ...
Slide 1
Slide 1

...  Chromosomal theory of inheritance • Chromosomes are carriers of genetic information. ...
Patterns of Inheritance
Patterns of Inheritance

... Repetitive sequences may serve to stabilize DNA’s bond with associated proteins. Mutations can convert inactive DNA sequences into active genes, or inactivate functional genes  may be a source of new alleles in natural selection. ...
Chromosome Segregation in Budding Yeast: Sister Chromatid
Chromosome Segregation in Budding Yeast: Sister Chromatid

... Once all the chromosomes have properly attached to microtubules, an enzyme known as separase becomes active and cleaves cohesin, thereby triggering the separation of sister chromatids to opposite poles (Figure 1). This process is modified during meiosis, which produces haploid gametes from a diploid ...
transcriptome analyses reveal differential gene - ePIC
transcriptome analyses reveal differential gene - ePIC

... noncalcifying flagellated form with organic scales that is haploid (1N, i.e., possessing the reduced, single set of chromosomes). A third form, known to be diploid, nonmotile, and uncalcified, may be a culture artifact (Klaveness 1972, Green et al. 1996). Until recently, coccolithophore research has ...
Chapter 23
Chapter 23

... the organism level (1860’s) – Concluded that plants transmit distinct factors to offspring – Based on his studies, he formulated the law of segregation ...
Chapter 23
Chapter 23

... the organism level (1860’s) – Concluded that plants transmit distinct factors to offspring – Based on his studies, he formulated the law of segregation ...
Chapter 23
Chapter 23

... the organism level (1860’s) – Concluded that plants transmit distinct factors to offspring – Based on his studies, he formulated the law of segregation ...
Printable version - Chromosome 18 Registry and Research Society
Printable version - Chromosome 18 Registry and Research Society

... This diagram depicts the structure of a chromosome. What looks like squatty little things under a microscope are actually very long linear chemical structures that have been precisely packaged. The chemical structure called DNA is shown in red and blue. This is the DNA double helix. The pairs of blu ...
Mendel 2014
Mendel 2014

... genotype of a homozygous dominant trait. What does Heterozygous mean? Write the genotype of a heterozygous individual. ...
Cytokinesis in Scytosiphon zygotes - Journal of Cell Science
Cytokinesis in Scytosiphon zygotes - Journal of Cell Science

... red dots) duplicated at this site. Each of the four centrosomes migrated to the future mitotic poles (Fig. 1C,D) and spindle MTs developed from them. In polyspermic zygotes, more than two mitotic spindle poles were formed, either four (not shown) or three (Fig. 1E-H). When the tripolar spindle was f ...
Genetics of Down Syndrome
Genetics of Down Syndrome

... only some (i.e. T-lymphocytes in a blood sample) can be stimulated in vitro to enter the cell cycle again and thus represent a selected cell population. In addition, cells are treated with colcemid. This substance arrests the chromosomes in the c-metaphase of mitosis and, at the same time, increases ...
1 Characteristics of Life
1 Characteristics of Life

... will find cells (Figure 1.2). Cells are the smallest structural and functional unit of all living organisms. Most cells are so small that they are usually visible only through a microscope. Some organisms, like bacteria, plankton that live in the ocean, or the Paramecium, shown in Figure 1.3, are un ...
Sex Linked Inheritance, Chromosome Mapping
Sex Linked Inheritance, Chromosome Mapping

... Euploidy is lethal in most animal species, but often tolerated in plants, where it has played a role in speciation and diversification. Monoploidy and polyploidy can result when either round of meiotic division lacks cytokinesis, or when meiotic nondisjunction occurs for all chromosomes. Punjab EDU ...
Mendel`s Theory
Mendel`s Theory

... Different versions of a gene are called alleles. An individual usually has two alleles for a gene, each inherited from a different parent. Individuals with the same two alleles for a gene are homozygous; those with two different alleles for a gene are heterozygous. The law of segregation states that ...
Life Science 7.gr- Essential Questions
Life Science 7.gr- Essential Questions

...  How are eukaryotes and prokaryotes alike and different?  How are the structure and roles of plant and animal cells similar/different?  How does the growth of a multi-cellular organism differ from the growth of a unicellular organism?  How do the parts of a cell enable it to survive? 7.L.1.3  W ...
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Meiosis



Meiosis /maɪˈoʊsɨs/ is a specialized type of cell division which reduces the chromosome number by half. This process occurs in all sexually reproducing single-celled and multi-celled eukaryotes, including animals, plants, and fungi. Errors in meiosis resulting in aneuploidy are the leading known cause of miscarriage and the most frequent genetic cause of developmental disabilities. In meiosis, DNA replication is followed by two rounds of cell division to produce four daughter cells each with half the number of chromosomes as the original parent cell. The two meiotic divisions are known as meiosis I and meiosis II. Before meiosis begins, during S phase of the cell cycle, the DNA of each chromosome is replicated so that it consists of two identical sister chromatids. In meiosis I, homologous chromosomes pair with each other and can exchange genetic material in a process called chromosomal crossover. The homologous chromosomes are then segregated into two new daughter cells, each containing half the number of chromosomes as the parent cell. At the end of meiosis I, sister chromatids remain attached and may differ from one another if crossing-over occurred. In meiosis II, the two cells produced during meiosis I divide again. Sister chromatids segregate from one another to produce four total daughter cells. These cells can mature into various types of gametes such as ova, sperm, spores, or pollen.Because the number of chromosomes is halved during meiosis, gametes can fuse (i.e. fertilization) to form a zygote with a complete chromosome count containing a combination of paternal and maternal chromosomes. Thus, meiosis and fertilization facilitate sexual reproduction with successive generations maintaining the same number of chromosomes. For example, a typical diploid human cell contains 23 pairs of chromosomes (46 total, half of maternal origin and half of paternal origin). Meiosis produces haploid gametes with one set of 23 chromosomes. When two gametes (an egg and a sperm) fuse, the resulting zygote is once again diploid, with the mother and father each contributing 23 chromosomes. This same pattern, but not the same number of chromosomes, occurs in all organisms that utilize meiosis. Thus, if a species has 30 chromosomes in its somatic cells, it will produce gametes with 15 chromosomes.
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