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Viruses
Viruses

... Viral Envelopes- Typically a lipid bilayer, w/ glycoprotein spikes to bind to specific receptor sites on host ...
Quick overview of immune system
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... – Specific binding to host cell receptor • Receptors involved in normal cell functions – Virus may regulate cell division for its own replication – Insertion of viral DNA into chromosome allows virus to hide from immune system ...
Global Dynamics of HIV Infection of CD4(+) T Cells and
Global Dynamics of HIV Infection of CD4(+) T Cells and

... We study the global dynamics of an HIV infection model describing the interaction of the HIV with CD4(+) T cells and macrophages. The incidence rate of virus infection and the growth rate of the uninfected CD4(+) T cells and macrophages are given by general functions. We have incorporated two types ...
- AAP Red Book - American Academy of Pediatrics
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... Scanning electron microscopy (SEM) of Vero E6 cells infected with severe acute respiratory syndrome-associated coronavirus. (A) The cell surface is covered with extracellular progeny virus particles, and progeny virus particles are being extruded from or attached to numerous pseudopodia on the infec ...
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... • HIV infects and ultimately destroys CD4+ , CCR5+ or CXCR4+ T cells, monocytes, & dendritic cells. ...
describe the basic function and structures of the immune system
describe the basic function and structures of the immune system

... the immune system. AIDS is caused by the human immunodeficiency virus (HIV). HIV is capable of becoming multi drug-resistant. HIV is a virus that affects T cells within the immune system. It attacks the RNA of the T cell, causing the T cell to alter its DNA structure to that of HIV. The result is th ...
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HIV and AIDS
HIV and AIDS

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aids_and_the_eye.
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HIV-AIDS powerpoint
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HIV/AIDS
HIV/AIDS

...  Pandemic: infectious disease that is spreading through human populations worldwide  estimated that there are 33.3 million people worldwide infected  2.6 million new HIV infections per year  1.8 million annual deaths due to AIDS 76% of those deaths occurred in sub-Saharan Africa.  attacks every ...
HIV/AIDS
HIV/AIDS

...  Pandemic: infectious disease that is spreading through human populations worldwide  estimated that there are 33.3 million people worldwide infected  2.6 million new HIV infections per year  1.8 million annual deaths due to AIDS 76% of those deaths occurred in sub-Saharan Africa.  attacks every ...
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HIV/AIDS - Sites at Penn State
HIV/AIDS - Sites at Penn State

... - sharing drug injection needles - childbirth (blood, amniotic fluid) - breast feeding ( breast milk) - occupational exposure - blood transfusions / organ transplant • It is not transmitted by air or water or casual contact. • It does not live long outside the body ...
Antiviral Drugs
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... In general, viruses have very small genomes which means they can encode a very limited number of their own proteins. For this reason, most viruses must use the proteins provided by their host in order to reproduce (make more viruses). In a way, viruses are parasitic, they bring very little with them ...
Viral and cellular microarray-based studies (virogenomics)
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... Current antiviral therapeutic strategies are centered on a relatively small number of non-structural protein targets in the viral genome; for instance, there are less than ten such targets in HIV, influenza A, and hepatitis C viruses. Although initially successful, the usefulness of these strategies ...
Virus - MabryOnline.org
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Human Immunodeficieny virus
Human Immunodeficieny virus

... classified of being in stage one of HIV (acute phase) and was immediately put on antiretroviral to help with her condition. Because she was detected early enough and was able to get on the antiretroviral medication she had a much better chance of surviving. She was scheduled for follow up visits to ...
Chapter 24
Chapter 24

... VIII. Progression of HIV infection • Asymptomatic phase - symptoms may not appear for years. (up to 10 years) • Declining Immunity - As the number of Tcells drops, a person develops a flulike illness. • AIDS - one or more opportunistic diseases develop. Over 30 such diseases have been identified. ...
Immunology
Immunology

... + some would defer therapy in subset of patients with stable CD4 cell count between 350-500/uL And plasma HIV RNA consistently below 5000-10000 copies/ mL ...
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HIV



The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through a number of mechanisms, including apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
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