• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Euroanaesthesia 2005 (Vienna, Austria)
Euroanaesthesia 2005 (Vienna, Austria)

... Cocaine is highly addictive; casual use is not possible once addiction occurs, and life -threatening side effects accompany its use. Cocaine produces sympathetic nervous system stimulation by blocking presynaptic uptake of norepinephrine and dopamine, thereby increasing the postsynaptic concentratio ...
ANNE ARUNDEL MEDICAL CENTER CRITICAL CARE
ANNE ARUNDEL MEDICAL CENTER CRITICAL CARE

... 50% of the maximum effect is observed within 45 minutes with IV continuous infusion. In treatment of acute hypertension in chronic hypertensives, discontinuation of infusion produced a 50% decrease in effect in approximately 30 minutes with gradually decreasing effect over the following 50 hours. Ni ...
ANTIPSYCHOTIC DRUGS & LITHIUM
ANTIPSYCHOTIC DRUGS & LITHIUM

... Tend to develop after years of therapy May appear as early as 6 months ...
Notes Heredity File
Notes Heredity File

... carried by chromosomes. Genes code for features of organisms. ...
Pharmaceutical Dosage Forms
Pharmaceutical Dosage Forms

... – The approval for clinical use is easier due to the prior experience with the original preparation – Must be pharmaceutically equivalent: same API, dose, pharmaceutical dosage form and the same route of administration as in original preparation – Must be clinically bioequivalent: i.e. it must be of ...
Antidepressants and Sedatives David G. Standaert, MD, Ph.D
Antidepressants and Sedatives David G. Standaert, MD, Ph.D

... Patients who are depressed may be suicidal - it is essential to inquiry about their intentions The response of an individual patient to a particular antidepressant cannot be predicted, and treatment often requires sequential trials of several drugs In severely depressed patients, ECT often produces ...
File - IMC Cardiology Rotation
File - IMC Cardiology Rotation

... the risk of CV death, MI, or stroke, while increasing TIMI major bleeding, TIMI minor bleeding, bleeding requiring transfusion, d/c of therapy due to bleeding. There was no significance observed in fatal bleeding or nonfatal Intracranial hemorrhage between study drugs and control. In addition, both ...
the diversion of public health
the diversion of public health

... (productivity of R&D, cost-effectiveness, market share), patent rates and their subsequent citations, or therapeutic value measures, the trend is not favourable in most of the literature. • 1975-2000: a study by P.E Barral for Aventis concluded that only 10 percent of patented drugs represented a th ...
Special Considerations for Unused Drugs Subject to Restricted
Special Considerations for Unused Drugs Subject to Restricted

... restricted distribution programs and create serious health risks for patients or others – Drug Collection and Takeback Programs – Drug Repository/Reuse Programs Presented at the 2008 International Symposium on Pharmaceuticals in the Home and Environment: Catalysts for Change, November 10-11, 2008 an ...
Methylphenidate - Isle of Wight NHS Trust
Methylphenidate - Isle of Wight NHS Trust

... pulse should be measured at each adjustment of dose and then at least every 3 months. Cerebrovascular disorders Cerebral vasculitis appears to be very rare idiosyncratic reaction to methylphenidate exposure. There is little evidence to suggest that patients at higher risk can be identified and the i ...
3.8 MB
3.8 MB

... the genetic  architecture of brain related phenotypes. • Imaging genetics has unique potential to identify novel drug  effects related to genetic mechanisms of brain disorders.  • imaging genetics has many opportunities for new directions  and new analyses as it enters adolescence.  Its future impac ...
Homo Administrans
Homo Administrans

... been conspicuous by their absence. Dr Song has tried to fill this gap. His team have gathered and analysed DNA from 123 Singaporean couples to see if it can be matched with a host of work-related variables, starting with job satisfaction. In this case Dr Song first checked how prone each participant ...
Phenote
Phenote

... Phenotype Character Table • List of Phenotype Character instances • Operations: New, Delete, Copy ...
HEREDITY
HEREDITY

... • Heredity Is the passing of traits from parents to offspring. • Genes on chromosomes control the traits that show up in an organism. • The different forms of a traits that a gene may have are alleles. ...
Putting it all together
Putting it all together

... Corticosteroids / Glucocorticoids • administered as PO, IV, Inhaled – Prednisone, Solumedrol, Beclomethasone – Side effects enhanced in PO and IV route ...
Chapter 16 Cholinesterase Inhibitors
Chapter 16 Cholinesterase Inhibitors

... Older adult patients require relatively small doses. Size and timing likely to be changed over course of therapy ...
When Patients Cannot Take Pills: Antiretroviral Drug - IAS-USA
When Patients Cannot Take Pills: Antiretroviral Drug - IAS-USA

... Currently, more than 20 antiretroviral drugs have been approved by the US Food and Drug Administration (FDA) for treatment of HIV infection. The majority of these drugs are available solely in tablet form for ease of administration; however, this limited formulation availability creates problems for ...
Breeding and Genetics - Faculty Website Listing
Breeding and Genetics - Faculty Website Listing

... • Proportion of the total phenotypic variation that is due to the variation in additive gene effects • In other words, the proportion of differences due to genetic effects and is important in the prediction of response rates from selection. • The square root of the variance is the standard deviation ...
FDA`s Acetaminophen Notice: A Snapshot of the Current Regulatory
FDA`s Acetaminophen Notice: A Snapshot of the Current Regulatory

... Acetaminophen is widely recognized as an effective and well-tolerated drug when used as directed, and has been used successfully to treat ailments in millions of patients. Notably, acetaminophen use is not associated with gastrointestinal problems that are associated with many other pain drugs, such ...
Drugs of Abuse - QML Pathology
Drugs of Abuse - QML Pathology

... through subsequent processes to ensure that the sample ultimately tested and reported upon is that which was received from the subject. Clearly urine collection entails processes that may be seen as encroaching upon the individual’s privacy. The Standard requires the collector only to ensure that th ...
genetic disorders web conference [Repaired]
genetic disorders web conference [Repaired]

... with a genetic condition known as Developmental Duplication (DD). Avoidance of mating carrier animals is an essential component of managing the incidence of genetic conditions as is the strategic use of DNA testing. AAA Statement of Certificate until confirmed by testing. ...
Inheritance of Sex
Inheritance of Sex

... What effect will that have on the frequency of the mutant allele in the population? ...
Determinants on Health and Their Interactions Genetic
Determinants on Health and Their Interactions Genetic

... various forms accounted for the inheritance of different visible traits or characteristics of an organism. This unit or particle was given the name gene by Wilhelm Johannsen in 1909. Prior to Mendel’s work it was assumed that the characteristics of the two parents were simply blended. Mendel showed ...
A Handbook for General Practitioners and Other Health
A Handbook for General Practitioners and Other Health

... This handbook is designed to assist doctors in the management of patients ceasing benzodiazepine use, and is to be read in conjunction with the two accompanying patient booklets. This material was written as a result of our experience in the treatment of people with problems of benzodiazepine depend ...
Hormone Replacement Therapy (Established Patient)
Hormone Replacement Therapy (Established Patient)

... performing diagnostic tests and providing anti-aging and hormone-balancing replacement therapy. 5. The PATIENT agrees to be responsible for the SERVICES. Our office does not accept insurance plan payments. We are a fee-for-service office. Patients are responsible for payment in full for services ren ...
< 1 ... 906 907 908 909 910 911 912 913 914 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report