• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Mechanisms of action in drug- coated Balloons
Mechanisms of action in drug- coated Balloons

... the amount of drug found in the tissue. In an experition following PCB use remains unknown. The need for mental study, it was demonstrated that delivery was drug carriers appears to be critical during the process of always more efficient when BMS were present (approxi- initial drug transfer. In addi ...
Geriatric Depression
Geriatric Depression

... All classes have proven efficacy in elderly patients ...
Efficacy and Safety of Dihydroartemisinin
Efficacy and Safety of Dihydroartemisinin

... stage. He received a full course of Artekin without incident, and the results of examination of a blood slide were negative on the second day. Although the patient remained aparasitemic and was eating, drinking, and urinating, he had persistent fever. On the fourth day, he became hypotensive, his co ...
Document
Document

... BMS* should be used in patients with high bleeding risk, inability to comply with 1 year of DAPT, or anticipated invasive or surgical procedures in the next year. DES should not be used in primary PCI for patients with STEMI who are unable to tolerate or comply with a prolonged course of DAPT becaus ...
Rozerem - Takeda
Rozerem - Takeda

... approximately 150% when ROZEREM was coadministered with fluconazole. ROZEREM should be administered with caution in subjects taking strong CYP2C9 inhibitors such as fluconazole [see Clinical Pharmacology (12.5)]. Donepezil: The AUC0-inf and Cmax of ramelteon increased by approximately 100% and 87%, ...
insomnia - BC Renal Agency
insomnia - BC Renal Agency

... identify and minimize contributing factors, if feasible. ...
An overview of the evidence and mechanisms of herb–drug
An overview of the evidence and mechanisms of herb–drug

... HDI is one of the most important clinical concerns in the concomitant consumption of herbs and prescription drugs. The necessity of polypharmacy in the management of most diseases further increases the risk of HDI in patients. The ability of intestinal and hepatic CYP to metabolize numerous structur ...
Topic 11 Introduction to medication safety
Topic 11 Introduction to medication safety

... • medications can greatly improve health when used wisely and correctly • yet, medication error is common and is causing preventable human suffering and financial cost • remember that using medications to help patients is not a risk-free activity • know your responsibilities and work hard to make me ...
Drug Facts Sheet Opium
Drug Facts Sheet Opium

... The intensity of opium’s euphoric effects on the brain depends on the dose and route of administration. It works quickly when smoked because the opiate chemicals pass into the lungs, where they are quickly absorbed and then sent to the brain. An opium “high” is very similar to a heroin “high”; users ...
Drugs Used in Gastrointestinal Disoders
Drugs Used in Gastrointestinal Disoders

... For acute ulcer therapy, full dose, and for ulcer prophylaxis, ½ usual dose, given at hs. For example: for active duodenal ulcer, Axid 150 mg bid or 300 mg @ hs. For maintenance therapy, Axid 150 mg @ hs For drug-induced ulcer prophylaxis, Cytotec, 100-200 mcg qid pc and hs or 200 mcg bid or tid - M ...
Design of colon specific drug delivery systems.
Design of colon specific drug delivery systems.

The statins: a drug class to celebrate
The statins: a drug class to celebrate

... rosuvastatin.9,10 Clearly, it is important to take efficacy into account when choosing a particular drug, but there are many other factors that need to be considered: evidence of benefit on clinical endpoints and safety in long-term RCTs, co-existent drug therapy, comorbidities in the individual pat ...
Single dose fluconazole in the treatment of pityriasis versicolor
Single dose fluconazole in the treatment of pityriasis versicolor

... efficacy with relapses due to the fact that large body areas cannot be treated adequately leading to recurrences. The ideal treatment would be a short course of an oral antifungal drug producing high clinical and mycological cure rates and low relapse rates. Fluconazole was selected for the treatmen ...
Document
Document

... A limitation of the statistical approach ...
Genetic variation: the raw material of evolution
Genetic variation: the raw material of evolution

... A limitation of the statistical approach ...
Chapter 11
Chapter 11

...  TT or Tt = dominant allele will show  tt = recessive allele will show  ¾ = dominant allele shown  ¼ = recessive allele shown  *3:1 ratio for dominant trait ...
Indigenous drug combination in the treatment of rhinosinal infections
Indigenous drug combination in the treatment of rhinosinal infections

... day. Clinical improvement however, always preceded the stage of bacteriological sterility as revealed by the smear and culture reports. In two cases, the patients returned after about a fortnight with similar symptoms as before (cases 11 and 16). Nevertheless, they recovered with a second course of ...
Inconspicuous and Miscalculated Opioid Risks
Inconspicuous and Miscalculated Opioid Risks

... Methadone 40mg; Oxycodone 120mg;  Hydromorphone 48mg Rennick A, Atkinson T, Cimino N, McPherson ML, Fudin J. Variability in Opioid  Equivalence. (Poster: 9‐236). American Society of Health‐System Pharmacists (ASHP)  2013 Midyear Clinical Meeting and Exhibition in Orlando FL. ...
呼吸系统用药(汤慧芳2015V2)
呼吸系统用药(汤慧芳2015V2)

... • It also exhibits inhibitory activity against the effects of free radicals produced by cigarette smoke. Clinical use: • chronic obstructive lung disease : reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sp ...
Genetics
Genetics

... Genotype = _____ ...
Introduction to Osmosis and Diffusion
Introduction to Osmosis and Diffusion

... Genotype = _____ ...
Freeman 1e: How we got there
Freeman 1e: How we got there

... • If the 2 alleles are represented by LM and LN, what genotypes and phenotypes are possible? • If a man with this blood group, LMLN, had a child with a MLN, what are the odds that woman of this blood group, L Answer: their child would be of the M, LMLN, and LNLN Genotypes could be:MN LMLphenotype? A ...
Outcome Statement 1 October 2015
Outcome Statement 1 October 2015

... DUSC reviewed the utilisation of the following PBS medicines/groups of medicines in October 2015: Pregabalin for neuropathic pain Over 430,000 people were dispensed pregabalin in the second year of availability through the PBS. The number of people treated and the number of prescriptions dispensed h ...
Pregabalin STADA 25 mg hard capsules Pregabalin STADA
Pregabalin STADA 25 mg hard capsules Pregabalin STADA

... at how much the medicine reduced the number of seizures patients had after 11 to 12 weeks. About 45% of the patients taking 600 mg Pregabalin a day and about 35% of those taking 300 mg Pregabalin a day had a reduction in seizures of 50% or more. This compared with about 10% of the patients taking pl ...
Here - Mainely Science
Here - Mainely Science

... he would see in their offspring  6) Mendel made 3 conclusions (2 of which were part of his Law of Segregation). What  was his first conclusion not including the Law of Segregation.? ​ ...
< 1 ... 755 756 757 758 759 760 761 762 763 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report