• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Eculizumab (Soliris®) for Atypical Haemolytic Uraemic Syndrome
Eculizumab (Soliris®) for Atypical Haemolytic Uraemic Syndrome

... Risk of onset of aHUS post transplantation Some assessment of risk of aHUS post transplantation is possible, although definitive characterisation of an individual’s level of risk is difficult. Clinical assessments in Australian practice are based on identifiable genetic mutations and the patient’s ...
Chapter 1
Chapter 1

... Pharmacology • A drug is any chemical substance that produces a biologic response in a living system. • A drug is a substance used as medicine to aid in the diagnosis, treatment, or prevention of disease. • The science concerned with the origin, nature, effects, and uses of drugs is called pharmacol ...
Amines, what they are and what they do
Amines, what they are and what they do

... • Half life is about 12 hours. • Has a greater psychological effect than ...
BIOSTAT516 Statistical Methods in Genetic Epidemiology
BIOSTAT516 Statistical Methods in Genetic Epidemiology

... genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects (that) cause the same disease, often due to mutations at different loci on the same g ...
Genomics Post-ENCODE
Genomics Post-ENCODE

... • Hunting for genetic variants that influence gene expression  Linking genetic variants to changes in gene expression – regulatory variants or “expression quantitative trait loci” (eQTL)  These will be different between tissues ...
EVect of resumption of second line drugs in patients with rheumatoid
EVect of resumption of second line drugs in patients with rheumatoid

... course of parenteral gold. There is one more retrospective study in which only 36% of the patients who initially were in remission during gold treatment reached this therapeutic goal again with a second course of gold.11 In the present study the response rates three months after resumption of parent ...
Molecular Genetic Study of PTC Tasting in Basra
Molecular Genetic Study of PTC Tasting in Basra

... Study traits genetically help us to understand the human dynamic, as traits have different frequencies in different populations that has been used to evaluate and analyze evolution forces as well as taxonomy of human race (Padmavathi, 2013). To realize human diversity, many genetic polymorphisms ind ...
PHAR 303 PHARMACEUTICAL CHEMISTRY I
PHAR 303 PHARMACEUTICAL CHEMISTRY I

... Approximately one in every four drugs currently on the market is some type of isomeric mixture. For many of these drugs, the biologic activity may only reside in one isomer (or at least predominate in one isomer). The majority of these isomeric mixtures are termed “racemic mixtures” (or “racemates”) ...
Proposed Kepler Re-Design
Proposed Kepler Re-Design

... surgery, and its long duration of action enhances the drug’s reliability. • OFRAMAX is recommended in a single dose of 1gm (in surgery with low risk of infection), or 2gm (in surgery with high risk of infection) for prophylaxis of perioperative infections. ...
Neuroleptics
Neuroleptics

... “Atypical” – derivatives of indole, benzodiazepine – they cause those negative reactions very rarely ...
Essential Standard: 1.1 Understanding the relationship between
Essential Standard: 1.1 Understanding the relationship between

... How can sex-linked traits be interpreted using Punnett squares? Pedigrees? ...
what are psychoactive drugs? - Florida Alcohol and Drug Abuse
what are psychoactive drugs? - Florida Alcohol and Drug Abuse

Medication Administration
Medication Administration

... – Compare name and medical record number on MAR with information on armband. ...
Introduction
Introduction

... inactive angiotensin I to angiotensin II which is a potent vasoconstrictor. At recommended doses, the effect of quinapril in hypertensive patients and in patients with chronic heart failure is maintained for up to 24 hours. It is indicated for the treatment of all grades of essential hypertension. Q ...
Name - Perry Local Schools
Name - Perry Local Schools

... F) In seals, the gene for the length of the whiskers has two alleles. The dominant allele (W) codes long whiskers & the recessive allele (w) codes for short whiskers. 1) What percentage of offspring would be expected to be true breeds for whiskers from the cross of two long-whiskered seals, one tha ...
Leukaemia Section t(3;5)(q26;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(3;5)(q26;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Transcrition factor; EVI1 targets include: GATA2, ZBTB16/PLZF, ZFPM2/FOG2, JNK and the PI3K/AKT pathway. Role in cell cycle progression, likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differentiation. ...
Mendelian Genetics Mono and Dihybrid Crosses, Sex
Mendelian Genetics Mono and Dihybrid Crosses, Sex

... • How can we determine the genotype of an individual with a dominant phenotype? Genotype possibilities (purple flower color)? PP or Pp ...
Patient Education ESCITALOPRAM
Patient Education ESCITALOPRAM

... ayahuasca, St. John's wort). This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. Some examples of these affected drugs include metoprolol, tramadol, trazodone, venlafaxine, and tricyclic depressants such as desipramine. Low-dose aspirin (usually 81-3 ...
bokay. s. sudiiinuka - Journal of the Indian Institute of Science
bokay. s. sudiiinuka - Journal of the Indian Institute of Science

... drugs, their derivatives or metabolites and model receptors are generated which form the zeroth order basis set for the intermolecular perturbative interaction energy calculations. These data are stored in the data base. Another feature of the approach is that the data is computed only once and can ...
Nimesulide (PDF, 210KB, File is accessible)
Nimesulide (PDF, 210KB, File is accessible)

... peptic ulceration, history of gastrointestinal haemorrhage, ulcerative colitis or Crohn’s disease. Caution should be advised in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, selective ...
Introduction to the newest anticonvulsants
Introduction to the newest anticonvulsants

... with CBZ, don’t give if allergic to either. Mild inducer may affect BCP, decr dose with decr CrCl. Reported decr T3/T4 only. Unknown sig ...
Unit Test: Genetics Name: Date: Period: The diagram shows a plant
Unit Test: Genetics Name: Date: Period: The diagram shows a plant

... B. offspring that are identical to each other and the parent C. three diverse offspring D. offspring that will not able to reproduce ...
Memorandum
Memorandum

... This is in follow up to your letter to the Food and Drug Administration (FDA) dated October 14, 1997, making a submission of a new dietary ingredient pursuant to 2 1 U.S.C. 350b(a)(2) [section 4 13(a)(2) of the Federal Food, Drug, and Cosmetic Act (the Act)]. Your letter notified FDA of your intent ...
Medication Administration
Medication Administration

... – Compare name and medical record number on MAR with information on armband. ...
TOTAL MARKS: 100
TOTAL MARKS: 100

... A. Solutions have a slower onset of effect compared to suspensions B. Solutions do not undergo disintegration process C. Solutions are cheaper and easy to mass produce compared to tablets D. Solutions should always contain one solute dissolved in a solvent E. Solutions usually have a longer shelf-li ...
< 1 ... 728 729 730 731 732 733 734 735 736 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report