• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
PATIENT INFORMATION SHEET CHRONIC MIGRAINE
PATIENT INFORMATION SHEET CHRONIC MIGRAINE

... Stop any vomiting – Use rectal Domperidone instead of oral preparation – 30-60mg up to twice daily Avoid anti-sickness drugs that reduce gastric emptying (e.g. buccastem, stemetil, cyclizine, etc). Over-hydrate at the beginning of the attack with 1 to 2 pints of ...
Genetics Practice Quiz Key
Genetics Practice Quiz Key

... 10. Roberto was in a serious car accident and when he was in the emergency room the doctor decided he needed a unit of blood. Roberto’s blood was sent to the lab for typing. Anti-A antibody was added to one test tube of his blood and Anti-B antibody was added to the other. No agglutination or clump ...
Drugs Used in the Treatment of Gastrointestinal Diseases
Drugs Used in the Treatment of Gastrointestinal Diseases

PowerPoint to accompany Hole`s Human Anatomy and Physiology
PowerPoint to accompany Hole`s Human Anatomy and Physiology

... • People affected produce several symptoms that vary ...
Chemical Teratogenesis
Chemical Teratogenesis

... • drug or other foreign substance • reactive metabolite • conjugate or oxidise • excretion ...
Geri-RxFiles - Pain Management in Older Adults
Geri-RxFiles - Pain Management in Older Adults

...  If pain is chronic, consider both pain & function! Elimination of pain is often not realistic,  & if pursued, may come at a cost of functional impairment & adverse events (e.g.  confusion/fall risk).     Self Report of Pain: important due to subjective nature of pain; obtain where possible.   Ph ...
Drug receptors and Pharmacodynamics
Drug receptors and Pharmacodynamics

... The extent of inhibition depends on the antagonist’s concentration. Thus the extent and duration of an antagonists action depends upon its concentration in the plasma which in turn is influenced by the rate of its metabolic clearance or excretion. Different patients receiving a fixed dose of propran ...
6-作用于神经系统的药物
6-作用于神经系统的药物

...  receptor, 与镇痛无关, 兴奋可引起幻觉, 焦虑和 烦 ...
Principles of Heredity
Principles of Heredity

... ! = factorial= number multiplied by each lower number until reaching 1 5! = 5 x 4 x 3 x 2 x 1 3! = 3 x 2 x 1 = 3 x 2! 2! = 2 x 1 ...
RT101 Basic Therapeutics
RT101 Basic Therapeutics

... Loading dose of 4 mg per kg of body weight Maintenance dose of 1 mg per kg Therapeutic serum levels: 100 to 150 mcg/100ml ...
Olanzapine and amenorrhea
Olanzapine and amenorrhea

... In a double-blind, olanzapine, placebo and haloperidol controlled trial, prolactin elevations with olanzapine were lower than with haloperidol, but was statistically relevant (doses of 10 ± 2.5 mg/day and 15 ± 2.5 mg/day) compared with placebo. In the olanzapine group an early increase in serum prol ...


... accept conflictual material should also be associated with the reduction of defensiveness. This implies a lessening of guilt and ...
Policy Statement Bevacizumab for the treatment of neovasucular
Policy Statement Bevacizumab for the treatment of neovasucular

... off-label (http://www.gmc-uk.org/guidance/ethical_guidance/prescriptions_faqs.asp) including obtaining informed consent from the patient and understand that responsibility for prescribing drugs outside the terms of the product licence remains with the prescriber. 2. All patients treated within these ...
To Study the Utilization Pattern of Nasal Decongestants and their
To Study the Utilization Pattern of Nasal Decongestants and their

... prescribing policy in this institution use of branded preparations was high. Prescribers need to be appraised with benefits of generic prescribing. In this study, 67% of total drugs prescribed were FDCs (91.6%; Table 2). None of the FDC’s used in the study was recommended by the WHO.10 Higher use of ...
Jubilant HollisterStier, LLC 11/27/13
Jubilant HollisterStier, LLC 11/27/13

... products. The April 2013 shutdown activities on SVP (b)(4) included removal of the existing (b)(4), rebuilding of the(b)(4) upgrade, and replacement of (b)(4). On SVP(b) (4) the (b)(4) was upgraded on the (b)(4), which included replacement of the (b) (4). Major facility repairs in the April 2013 shu ...
O A RIGINAL RTICLE
O A RIGINAL RTICLE

... human parasite has been identified to be P. knowlesi, which has the long-tailed and pig-tailed macaque monkeys as the natural hosts [57,68]. P. falciparum is the leading cause of disease in most parts of the world, producing about 250 million new infections, with a mortality estimate of about 1 mill ...
Introduction to Toxicology
Introduction to Toxicology

... poisons. Six classes of poisons were established, based mainly on their toxic effects. He also isolated arsenic from a variety of postmortem specimens and was the first to articulate the fact that poisons must be absorbed, or enter the blood, to manifest their toxic effects. ...
SAS Clinical Programming In 18 Easy Steps
SAS Clinical Programming In 18 Easy Steps

... of the new drug. Phase I trials are usually conducted with open label, i.e. the subjects are aware of the drugs that they are being given. For the first time, the Test drug is introduced to humans. Testing occurs in a small number of healthy volunteers (20 to 100). This initial phase of testing usua ...
7-Skeletal_Muscle_Relaxants modified
7-Skeletal_Muscle_Relaxants modified

... to its NM receptor and prevent depolarization of the motor end plate (d-tubocurarine) 2) Agonist (depolarizing) neuromuscular blocking drugs produce excessive depolarization of the motor end plate by causing excessive stimulation of the NM receptor (Succinylcholine) ...
Development of Tamper Deterrent Formulations
Development of Tamper Deterrent Formulations

... o July, 2009, the company announced the receipt of FDA complete response letter and indicated there were issues regarding the potential abuse deterrent benefit of the product but cited no additional clinical trials required4 o April 2010, the FDA advisory Committees voted they don’t have enough evid ...
Post-Implant Clinical Care
Post-Implant Clinical Care

... • Indicated for patients unresponsive to oral meds or with SE’s • Delivered directly to intrathecal space affording much higher drug concentration • Implantable system allows non-invasive monitoring & adjustments ...
Amitriptyline - Drs. Foster and Smith
Amitriptyline - Drs. Foster and Smith

... Give the oral form with food to decrease the risk of side effects such as vomiting. Amitriptyline in tablet form is very bitter, and it may be difficult to give in pill form. Compounding pharmacies can make an oral liquid form or transdermal (topical) gel, which may be easier to administer. If using ...
Presentation on opioid use disorders for crisis
Presentation on opioid use disorders for crisis

... Beyond Clinical Knowledge • Counsellors play a significant role in a patient’s early recovery – Counsellor attitude toward a patient with an OUD during their first treatment encounter can influence their future participation in treatment • Showing compassion is essential as often patients seek help ...
Latanoprost Orifarm eye drops, solution ENG SmPC
Latanoprost Orifarm eye drops, solution ENG SmPC

... aged 3 - <12 years and 6 times higher in children <3 years compared to adults, however a wide margin of safety in respect to systemic side effects were maintained (see section. 4.9). The median time to ...
Activity 1: I`m all Keyed Up - Pitt-Bradford
Activity 1: I`m all Keyed Up - Pitt-Bradford

... One of the first steps used to study how traits are inherited is to design a key. Using the letters of the alphabet, simply select a letter to symbolize the trait you are investigating. For example, you might want to use the letter “n” to symbolize the length of the dragon’s neck. The upper case ver ...
< 1 ... 656 657 658 659 660 661 662 663 664 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report