• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
出國類別:進修 - 公務出國報告資訊網
出國類別:進修 - 公務出國報告資訊網

... efficacy in a less confounded base. Through the process of randomization, RCTs can eliminate spurious causality and lessen further bias (Rosenberger and Lachin 2002). Also, RCT could enhance the power of evidence and make conclusion more solid. Considering the treatment effectiveness of injectable d ...
1 is
1 is

... ~ Gtl1.Rt( 1 wl/;r£ I ...
Comings et al. (1996)
Comings et al. (1996)

... The D2 Receptor Gene in Gambling Both prevalence and frequency were higher in pathological gamblers than in controls. When the 102 pathological gamblers who had completed the gambling questionnaire were divided according to their gambling scores, those scoring in the upper half had higher prevalenc ...
Gregor Mendel - BEHS Science
Gregor Mendel - BEHS Science

... simply means that during gamete formation, allelic pairs that code for different traits assort independent of each other ...
The First Amendment And Off-Label Promotion
The First Amendment And Off-Label Promotion

... physician who also promoted Xyrem for off-label indications, including fibromyalgia, EDS, sleepiness, weight loss and chronic fatigue.26 Pursuant to its misbranding regulations, the U.S. government filed a two-count misdemeanor information against Caronia.27 Count one of alleged that, between March ...
Creating records and analysis of deposited data
Creating records and analysis of deposited data

... Steps to creating a DECIPHER Patient 1. Patient Data: Some basic information about the patient is required to be able to create a record in DECIPHER. These include age of the patient, sex, an internal reference that links this record in DECIPHER to the notes in the clinic, parental affected status, ...
Pharmacokinetics - PHARMACEUTICAL REVIEW
Pharmacokinetics - PHARMACEUTICAL REVIEW

... o Active transfer process (carrier mediated transfer): This process can work against conc. gradient & continue until all drug has been transferred, thus equilibrium does not occur. It is a continuous process. ...
Rx OPIOIDS – Friend or Foe
Rx OPIOIDS – Friend or Foe

... Better suited to evaluate pain control – Determine if pain is treated properly Drug Hoarding = Fear of running out…Saves meds for worst pain Unauthorized dose > = Tolerance…Disease progression…Poor pain relief Multiple Drs.= Dr.Shopping?...Poor Tx…Insurance Px…Need to know each other Internet-Street ...
Critical Care of the Morbidly obese Patient Louis Brusco Jr, MD, FCCM
Critical Care of the Morbidly obese Patient Louis Brusco Jr, MD, FCCM

... from fat stores and enhance protein breakdown to fuel gluconeogenesis. The critically ill patient will degrade up to 50% more body protein than the nonobese patient, in part because the inflammatory response increases the need for paralyzing agents, sedation, prolonged bed rest from longer times on ...
Session 59 – Shoults, Stefanie
Session 59 – Shoults, Stefanie

... JWH-250 arrived a little later and has also cycled out. JWH-081 was part of a second wave that has already completed its cycle. JWH-122 was part of the same wave but has persisted in popularity and is part of the current scene. AM-2201 was part of the same second wave and has gained in popularity, p ...
Population Genetics
Population Genetics

... • The Hardy-Weinberg theorem states that the processes involved in a Mendelian system have no tendency to alter allele frequencies from one generation to another. – The repeated shuffling of a population’s gene pool over generations cannot increase the frequency of one allele over another. Copyright ...
Shan Chikhale, Professor of Pharmaceutical Sciences, School of
Shan Chikhale, Professor of Pharmaceutical Sciences, School of

... preparing, preserving, compounding and dispensing…  Heritage of pharmacy, spanning some 5000 years, has focused on provision of pharmaceutical products for patients. ...
clinical pharmacokinetics-4
clinical pharmacokinetics-4

... o Active transfer process (carrier mediated transfer): This process can work against conc. gradient & continue until all drug has been transferred, thus equilibrium does not occur. It is a continuous process. ...
DOSE DEPENDENT EFFICACY OF LACOSAMIDE IN PROTECTION OF PENTYLENETETRAZOL  Research Article
DOSE DEPENDENT EFFICACY OF LACOSAMIDE IN PROTECTION OF PENTYLENETETRAZOL Research Article

Polymorph Impact on the Bioavailability and Stability of Poorly
Polymorph Impact on the Bioavailability and Stability of Poorly

... have attracted attention for improving the dissolution rate of poorly water-soluble drugs [3]. Drug particle size reduction, affecting the dissolution rates, has been revealed one of oldest strategies for improving bioavailability of drugs and has been frequently applied in the pharmaceutical indust ...
Pain Management Guidelines
Pain Management Guidelines

... SCRIPTS utilization should be part of every patient’s initial evaluation and subsequent monitoring program and is considered the standard of care. Failure to utilize SCRIPTS to assess risk of opiate/sedative prescribing may be considered misconduct by the responsible regulatory board, depending upon ...
Standard phrases - Midlands Medicines
Standard phrases - Midlands Medicines

... STANDARD PHRASES Evidence ...
Statin Effects on Muscle and Kidney
Statin Effects on Muscle and Kidney

... HMG-CoA reductase inhibitors (statins) have shown benefits in preventing some cardiac events. Initial studies indicated very few adverse effects including rhabdomyolysis. However, significant evidence has accumulated to suggest that statin-induced muscle injury is an under-reported cause of signific ...
Use of textile biomaterials for the topic treatment of chronic venous
Use of textile biomaterials for the topic treatment of chronic venous

... allowed obtaining new biomaterials comfortable for the patient. These biomaterials were made by grafting the polymers on textile supports and including the drugs used in the CVD topic treatment in the obtained grafted structures. Many aspects that may impact on the biomaterials efficiency have been ...
Jan p. 2 - Epocrates
Jan p. 2 - Epocrates

... when a clinically important DDI was identified. A false negative occurred when a clinically significant interaction was not identified but should have been. A true negative occurred when a clinically unimportant DDI was not identified, and a false positive occurred when a DDI was identified but was ...
The Need and Importance of Dose Flexibility - Accu
The Need and Importance of Dose Flexibility - Accu

... prevalent, comprising approximately 21% of all U.S. oral solid medications today.7 The principal disadvantage of capsules, however, is the lack of flexibility, making dose adjustments impossible without multiple daily dosages or multiple dosage strengths. Tablets, on the other hand, are the most pop ...
Genetic and Environmental Factors Contributing to Cardiovascular
Genetic and Environmental Factors Contributing to Cardiovascular

... case–control study design. Most importantly, association does not prove causation, and spurious associations may result for a number of reasons, including recall bias, resulting in conflicting or inconsistent findings. The current study’s observation that maternal drug use during pregnancy is increasi ...
Drug/Application
Drug/Application

...  Ribosomes are the site of protein synthesis in both prokaryotic and eukaryotic  The differences in ribosomes between bacteria and humans provide a useful target for antibiotics  Selective toxicity for bacteria ...
Heredity - questions
Heredity - questions

... (f) If Jane had been normal, what are the possible genotypes of the grandparents? (g) Is it possible that the allele for PKU is sex-linked? 13 One form of colour-blindness is a sex-linked inherited condition controlled by a recessive allele. Use the symbols X and Y for the sex chromosomes and N and ...
Genetic Disorders and the Arabian Horse
Genetic Disorders and the Arabian Horse

... produced an affected foal does not mean it is "clear." Because stallions can sire many offspring, they are more likely to eventually be revealed as a carrier. Mares, however, may be unrecognized carriers. Even if bred to a carrier stallion, statistical probability may mean that they never produce an ...
< 1 ... 595 596 597 598 599 600 601 602 603 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report