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Medications Requiring Prior Authorization for Medical
Medications Requiring Prior Authorization for Medical

... There may be additional drugs subject to prior authorization or other plan design restrictions. Please consult your plan for further information. This list represents brand products in CAPS, branded generics in upper- and lowercase Italics, and generic products in lowercase italics. This is not an a ...
Emerging Drug List SIBUTRAMINE
Emerging Drug List SIBUTRAMINE

... Sibutramine is a beta-phenylethylamine that exhibits monoamine reuptake-inhibitor activity for norepinephrine, serotonin, and to a lesser extent, dopamine. The precise mechanism by which sibutramine acts as an anorexiant is not known. However, sibutramine is believed to act by decreasing food/energy ...
Read More
Read More

... worldwide. Globally, the companies of Merz Pharma Group are focused on medications for treating neurological and psychiatric illnesses, and they have assumed a leading role in the field of Alzheimer’s disease research. Founded in 1908, Merz Pharma Group is a privately-owned company headquartered in ...
Genetic analysis of TTF2 gene in congenital hypothyroid infants with
Genetic analysis of TTF2 gene in congenital hypothyroid infants with

... a known polymorphism in ser 273 (TCC.TCT) in 74% unrelated patients. Furthermore, we found that the length of the alanine tract of TTF2 was 14 in some of our TD patients. This data may point to a role of the TTF2 polyA tract length in modulating genetic susceptibility to TD. ...
Analysis of sequence variations in the factor VIII gene in
Analysis of sequence variations in the factor VIII gene in

... reaction. Binding Buffer was removed, using a magnet to separate the beads, and the beads were resuspended in 30µl 2x Binding Buffer per reaction. 30µl bead mix were added to each reaction tube and left at room temperature for 15min. The supernatant was removed, using a magnet. 20µl hydroxylamine so ...
OVERVIEW
OVERVIEW

... agonists or inverse agonists, they do, however, block the effects of both the agonists and inverse agonists, for e.g. flumazenil opposes the action of both BZD and beta carboline.. Only a few inverse agonists are identified. An example of a receptor that possesses basal activity is the GABAA recepto ...
Pulmonary Hypertension Agents: Adcirca, Revatio, Adempas
Pulmonary Hypertension Agents: Adcirca, Revatio, Adempas

...  Brand  Generic Generic equivalent drugs will be substituted for brand-name drugs unless you specifically indicate otherwise. ...
Introduction - Obafemi Awolowo University, Ile-Ife
Introduction - Obafemi Awolowo University, Ile-Ife

... Reports of counterfeit drugs world-wide Trade in fake medicines is more prevalent in countries with weak drug regulation and enforcement, scarcity or erratic supply of basic medicines, unregulated markets and unaffordable prices. But as counterfeiting becomes more sophisticated, these products are i ...
Pharmacy Newsletter - Gold Coast Health Plan
Pharmacy Newsletter - Gold Coast Health Plan

... Asthma is a significant chronic illness. At Gold Coast Health Plan (GCHP), approximately 12,000 members – mostly children – have been diagnosed with asthma. In addition to the preventive measures that a patient and his/her family can take, medication management is the primary means of treating this ...
Gastrocrom - Meda Pharmaceuticals
Gastrocrom - Meda Pharmaceuticals

... Pediatric Use: In adult rats no adverse effects of cromolyn sodium were observed at oral doses up to 6144 mg/kg (approximately 25 times the maximum recommended daily oral dose in adults on a mg/m2 basis). In neonatal rats, cromolyn sodium increased mortality at oral doses of 1000 mg/kg or greater (a ...
malaria
malaria

... tafenoquine which are more active & slowly metabolized, t½=3-6h For radical cure of acute vivax and oval malaria”:chloroquine is given to eradicate erythrocytic forms and then primaquine(30mg daily for 14 days) to eradicate liver hypnozoites ...
File - NCEA Level 2 Biology
File - NCEA Level 2 Biology

... Guidance for assessment This paper has FOUR questions. The exemplars and papers provided by NZQA only have THREE. It is up to individual schools to remove questions if they wish to do so. The new method of assessment is intended to be more holistic, with evidence being assessed from the top (E8) dow ...
Update on Pharmacologic Strategies
Update on Pharmacologic Strategies

... • Cognitive Impairment: May cause disturbances in attention or memory. Caution patients about operating automobiles or hazardous machinery when starting treatment ...
First Major European Viral Hepatitis Study Reports Serious Gaps in
First Major European Viral Hepatitis Study Reports Serious Gaps in

... know is that every year 171 000 people die due to viral hepatitis related causes (approximately 2% of all deaths annually). This translates to more than 400 deaths from hepatitis every day. The vast majority of these deaths are due to late effects of chronic HBV and HCV infections (which caused an e ...
Correspondence 1 5 M A R C H
Correspondence 1 5 M A R C H

... crobial treatment of the original infection—too long a time interval to reasonably anticipate a relapse [2, 3]. In addition, 29 (90.6%) of 32 recurrences occurred during June–August—exactly the months in which reinfection would naturally occur [2, 4]. The P value for such seasonality occurring by c ...
Numbering the hairs on our heads: The shared
Numbering the hairs on our heads: The shared

... variation in human morbidity and mortality. As represented in Fig. 1B, doing so involves unraveling the same transformations in and between G and P spaces as does understanding the process of evolution. Epigenesis and transmission are the same in both realms; the determination of disease state from ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
Handout - 6 - CM - Outline Genomic Model for HL7 V2

... This is the first one. Needed for controlling input into form. These are not LOINC codes that would be included in the HL7 ...
FRAMEWORK - SHARED CARE
FRAMEWORK - SHARED CARE

... If you can answer YES to all these questions (after reading this shared care guideline), then it is appropriate for you to accept prescribing responsibility. If the answer is NO to any of these questions, you should not accept prescribing responsibility. You should write to the specialist within 14 ...
Genetics Understanding Inheritance What controls traits?
Genetics Understanding Inheritance What controls traits?

... Unlike the genes in Mendel’s pea plants, some genes have more than two alleles, or multiple alleles. Human ABO blood type is an example of a trait that is determined by multiple alleles. There are three alleles for the ABO blood type—I A, I B, and i. The way the alleles combine results in one of fou ...
Off-Base - Medicare Rights Center
Off-Base - Medicare Rights Center

... percent said they prescribed medications for off-label uses.9 A 1993 University of California survey of doctors who treated patients with HIV indicated that 42 percent of all such drug treatment was off-label, and that 90 percent of patients were prescribed at least one off-label medication. 10 The ...
Drug-induced acute pancreatitis
Drug-induced acute pancreatitis

... hormone replacement therapy (HRT), arteriolar thrombosis is a theorized mechanism of action. Published case reports of drug-induced AP exist for at least 40 drugs of the top 200 most prescribed medications. This article reviews data on five drug classes or drugs commonly associated with AP: 3-hydrox ...
A REVIEW ON ANTHELMINTIC DRUGS AND THEIR FUTURE SCOPE  Review Article    PIYUSH YADAV*, RUPALI SINGH 
A REVIEW ON ANTHELMINTIC DRUGS AND THEIR FUTURE SCOPE  Review Article    PIYUSH YADAV*, RUPALI SINGH 

... The anthelmintic drugs show their effects on the human body and their regular activities by causing helminthiasis which is a very severe parasitic  disease. Mostly population and the livestock parasites produce the resistance against the helminths parasites which causes morbidity and mortality.  Thi ...
ijlbpr_23
ijlbpr_23

... Crohn's disease is thought to be an autoimmune disease, in which the body's immune system attacks the gastrointestinal tract, causing inflammation, it is classified as a type of inflammatory bowel disease. The microspheres carrier for the delivery of the dosage form to the colon is composed of physi ...
Genetic Testing Guide - Clinpath Laboratories
Genetic Testing Guide - Clinpath Laboratories

... local laboratory referral forms – Sullivan Nicolaides Pathology, Douglass Hanly Moir Pathology and Barratt & Smith Pathology, Melbourne Pathology, Clinipath Pathology, Clinpath Laboratories, Hobart Pathology, Launceston Pathology, North West Pathology, Capital Pathology and Southern IML Pathology. M ...
Gabapentin in the amelioration of neuropathic pain
Gabapentin in the amelioration of neuropathic pain

... years of age and older, in particular in those suffering from more severe acute pain and rash. Administration of antiviral drugs reduces the duration of pain associated with HZ. The pathophysiology of PHN may be distinctly different between patients with either reduced or increased ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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