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STUDIES ON FORMULATION AND EVALUATION OF OSMOTICALLY CONTROLLED DRUG Research Article
STUDIES ON FORMULATION AND EVALUATION OF OSMOTICALLY CONTROLLED DRUG Research Article

... Present investigation is to develop controlled osmotic tablet of Carbamazepine with an aim of increasing its therapeutic effectiveness for extended period of time thus reducing dose frequency and side effects. As new innovation in oral controlled plasma drug delivery it avoids fluctuation in drug co ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... endocrine disorder in women of reproductive age and is considered as a multifactorial reproductive, cosmetic and metabolic problem. The etiology of PCOS is not well understood and its pathophysiological and molecular basis is still obscure. PCOS is likely to be the outcome of a number of both geneti ...
Slide 1
Slide 1

...  CANNOT BE DEMETHYLATED BY HUMANS  LAXATION WITHIN HOURS ...
VT PowerPoint Template5
VT PowerPoint Template5

... Tissue Residues At 5 x T1/2 (after you stop dosing) 97% has been eliminated.  Make sure you use the longest half-life  Metabolites MAY be more important than the drug  Absorption may have the longest half-life. ...
pharmacy math jeopardy! - Alaska Pharmacists Association
pharmacy math jeopardy! - Alaska Pharmacists Association

... 1. Give the basic formula used in all IV calculations. 2. What is the flow rate in ml/hr for an IV of 600 ml to be given over 10 hours? 3. What is the flow rate in ml/min for this IV? 4. How long will it take for a 1000ml IV running at 200ml/hr to run ...
- journal of evolution of medical and dental sciences
- journal of evolution of medical and dental sciences

... The BIS index is a numerically processed, clinically-validated EEG parameter that measures the effects of anesthesia and sedation on brain.10 According to the manufacturer this monitoring may act as an additional vital sign that allows the clinicians to deliver anesthesia according to the patient ne ...
Glucophage (metformin)
Glucophage (metformin)

... discontinued prior to any intravascular radiocontrast study and for any surgical procedure. The onset of lactic acidosis often is subtle, and accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, increasing somnolence and non-specific abdominal distress. There may ...
MICRONEEDLES: AN INNOVATIVE APPROACH TO TRANSDERMAL DELIVERY- A REVIEW  Review Article
MICRONEEDLES: AN INNOVATIVE APPROACH TO TRANSDERMAL DELIVERY- A REVIEW Review Article

... stratum corneum also known as horny layer is ought to be the outermost layer of the skin and has been identified as the principal barrier for penetration of most of the drugs. The outermost layer of the skin represents the final stage of epidermal cell differentiation. The thickness of this layer is ...
Tamoxifen Citrate 20mg X 30 Ml - Is It Safe To
Tamoxifen Citrate 20mg X 30 Ml - Is It Safe To

... Cram.com makes it easy to 11 Feb 2014 A full list of the Top 200 Drugs used in the mobile app FlashRX by ClinCalc citrato de tamoxifeno 20mg comprar If we’re lucky we might meet up with some BOOBs (Babes Out On Bikes) from the Wollongong area nolvadex 20 mg fiyat俚good website to buy nolvadex A ...
LCA Oral SACT Counselling Handbook
LCA Oral SACT Counselling Handbook

... SACT is taken over a long period of time, the responsibility to recognise and report any side effects rests with the patient. Therefore, patient education must emphasize recognition of early signs and symptoms and when to report problems. Normally, an oncology clinician will see the patient and give ...
Macugen, INN-pegaptanib sodium
Macugen, INN-pegaptanib sodium

... Macugen was administered to 892 patients in controlled studies for one year (total number of injections = 7545, mean number of injections/patient = 8.5) at doses of 0.3, 1.0 and 3.0 mg. All three doses shared a similar safety profile. In the 295 patients who were treated with the recommended dose of ...
design and development of lornoxicam fast dissolving tablets by
design and development of lornoxicam fast dissolving tablets by

... 6.1 Need of the study The oral route of administration still continues to be the most preferred route due to its manifold advantages including ease of ingestion, pain avoidance, versatality, accurate dosage, self-medication and most importantly patient compliance.1-2 It has been shown that the disso ...
pph preoperative medication procedure
pph preoperative medication procedure

... Bleeding risk from SSRIs1 SSRIs can decrease intraplatelet serotonin concentrations and this may affect platelet aggregation [23]. Anecdotal reports have indicated a relationship between SSRI use and mostly minor bleeding complications, including easy bruising, petechiae and purpura, epistaxis and h ...
Snehalatha Bhashyam 1 , P. Krishna Prasad 2 , B
Snehalatha Bhashyam 1 , P. Krishna Prasad 2 , B

... butyropheneones (droperidol), benzamide (metoclopramide), Neurokinin receptor antagonists (NK1 antagonists) and Glucorticoids. Each drug used has its own merits and demerits like dry mouth, extrapyramidal signs, hallucinations, excessive sedation, headache and hypotension.6 5-hydroxytryptamine-3 (5- ...
Navigating Acid Suppression Options
Navigating Acid Suppression Options

Community Management - College of Pharmacy
Community Management - College of Pharmacy

... 4. Students are responsible for getting all evaluations and grades from the preceptor, including mid-term evaluation by the preceptor. 5. Students CANNOT do a rotation at a site where they have either received intern credit or worked before or during pharmacy school. Failure to notify the Experienti ...
Pedigree Genotyping - Wageningen UR E
Pedigree Genotyping - Wageningen UR E

... of alleles at one locus. Such specific combinations may be more favourable than expected from the average effects of the alleles. Such combinations are exploited in F1-hybrid cultivars and in vegetatively propagated crops, and are automatically identified by Pedigree Genotyping. The following theore ...
Drugs and Tox Key
Drugs and Tox Key

... 31. Is a schedule II controlled substance used in dental surgery. E 32. Is a popular “clubbing” drug in spite of a high number of deaths attributed to it. D 33. Is a schedule I drug that can be snorted, smoked, and injected gives the user an intense feeling of euphoria. A 34. Is a class of drugs tha ...
Immuneflu - BlueeyedCurse – A Holistic Health Resource for
Immuneflu - BlueeyedCurse – A Holistic Health Resource for

... analogize this approach to dropping a nuclear bomb when conventional weapons might be adequate. While some people wait until full-blown viral symptoms manifest, I don't have a choice. Life Extension is a 24-hour/day operation with no room for down time. I don't have the luxury of calling in sick jus ...
Lec -10-acetaminophen-toxicity
Lec -10-acetaminophen-toxicity

... Hemodialysis effective but is not generally indicated because antidotal therapy is so effective ...
ANTINOCICEPTIVE ACTIVITY OF FREEZE DRIED POWDERED MORINDA CITRIFOLIA L. FRUIT
ANTINOCICEPTIVE ACTIVITY OF FREEZE DRIED POWDERED MORINDA CITRIFOLIA L. FRUIT

... against the injurious agent caused by release of mediators such as prostaglandins, leukotrines, bradykinin, histamine, interleukin etc. from the tissue to kill those irritant substances [8]. NSAID’S and opiates are the drugs most widely used across the world to treat pain and inflammation associated ...
Investigating the Suitability of Isomalt and Liquid Glucose as Sugar
Investigating the Suitability of Isomalt and Liquid Glucose as Sugar

... Medicated boiled hard candy lozenges were prepared in a local candy industry on request. The candy based lozenges were prepared by heating and congealing method [8] in a candy based industry on request using Isomalt alone or in combination with liquid glucose as base, glycerine, citric acid artifici ...
JETREA® Preparation and Administration
JETREA® Preparation and Administration

... which include the use of sterile gloves, a sterile drape and a sterile eyelid speculum (or equivalent). Adequate anesthesia and a broad spectrum microbiocide should be administered according to standard medical practice. The injection needle should be inserted 3.5 - 4.0 mm posterior to the limbus ai ...
Review Article  SULFONYL UREAS FOR ANTIDIABETIC THERAPY, AN OVERVIEW FOR GLIPIZIDE    SHAMMI GOYAL1*, JITENDRA KUMAR RAI¹, R.K.NARANG¹, RAJESH K.S¹ 
Review Article  SULFONYL UREAS FOR ANTIDIABETIC THERAPY, AN OVERVIEW FOR GLIPIZIDE    SHAMMI GOYAL1*, JITENDRA KUMAR RAI¹, R.K.NARANG¹, RAJESH K.S¹ 

... 2)  Glipizide  reduces  blood  glucose  by  stimulating  insulin  secretion  and altering insulin sensitivity; the drug causes a sustained increase  in  glucose‐stimulated  insulin  secretion  in  most  patients  during  prolonged therapy.   3) Like other drugs belonging to the class of  sulfonylure ...
Genetic Testing for Dilated Cardiomyopathy
Genetic Testing for Dilated Cardiomyopathy

... including cardiac magnetic resonance imaging, exercise testing, right-sided catheterization with biopsy, and 24-hour ECG monitoring will uncover only a small number of additional etiologies for DCM. Approximately 35% to 40% of DCM cases are thus determined to be idiopathic after a negative workup fo ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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