C 3 R
... Cytochrome P450 (P450s) are involved in the metabolism of approximately 80% of the drugs currently on the market (1, 2). In some cases drugs can be oxidized by P450s to electrophilic reactive intermediates, which subsequently can react with nucleophilic functional groups in biomolecules such as prot ...
... Cytochrome P450 (P450s) are involved in the metabolism of approximately 80% of the drugs currently on the market (1, 2). In some cases drugs can be oxidized by P450s to electrophilic reactive intermediates, which subsequently can react with nucleophilic functional groups in biomolecules such as prot ...
PRODUCT MONOGRAPH PRIMAXIN® (imipenem and cilastatin
... Geriatric (≥65 years old): No dosage adjustment is required solely on the basis on age (see, DOSAGE and ADMINISTRATION, Geriatric). This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Bec ...
... Geriatric (≥65 years old): No dosage adjustment is required solely on the basis on age (see, DOSAGE and ADMINISTRATION, Geriatric). This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Bec ...
1 6111 METRONIDAZOLE VAGINAL GEL, 0.75%
... There were no deaths or serious adverse events related to drug therapy in a clinical trial involving 220 non-pregnant women who received metronidazole vaginal gel once daily at bedtime for 5 days. Metronidazole vaginal gel was discontinued in 5 patients (2.3%) due to adverse events. Adverse events j ...
... There were no deaths or serious adverse events related to drug therapy in a clinical trial involving 220 non-pregnant women who received metronidazole vaginal gel once daily at bedtime for 5 days. Metronidazole vaginal gel was discontinued in 5 patients (2.3%) due to adverse events. Adverse events j ...
Safety and Side Effects of CBD
... Additionally, CBD can be a substrate of UDPglucosyltransferase (Ujvary and Hanus, 2016). To our knowledge no studies exist so far on the question, whether this can also cause clinically relevant drug interactions in humans. ...
... Additionally, CBD can be a substrate of UDPglucosyltransferase (Ujvary and Hanus, 2016). To our knowledge no studies exist so far on the question, whether this can also cause clinically relevant drug interactions in humans. ...
Guidelines for the Use of Antiretroviral Agents in
... existing sections. Significant updates are highlighted throughout the document. ...
... existing sections. Significant updates are highlighted throughout the document. ...
ICH Q3D Guideline (Elemental Impurities)
... into other works, adapted, modified, translated or distributed under a public license provided that ICH's copyright in the document is acknowledged at all times. In case of any adaption, modification or translation of the document, reasonable steps must be taken to clearly label, demarcate or otherw ...
... into other works, adapted, modified, translated or distributed under a public license provided that ICH's copyright in the document is acknowledged at all times. In case of any adaption, modification or translation of the document, reasonable steps must be taken to clearly label, demarcate or otherw ...
Prokinetic agents: current aspects with focus on cisapride
... but also on the peripheral nervous system. Dopamine receptors have been found throughout the length of the gastro-intestinal tract, especially in the stomach, pancreas, mesenteric artery and lower segment of the gastrointestinal tract. Inhibition of dopamine secretion increases the release of acetyl ...
... but also on the peripheral nervous system. Dopamine receptors have been found throughout the length of the gastro-intestinal tract, especially in the stomach, pancreas, mesenteric artery and lower segment of the gastrointestinal tract. Inhibition of dopamine secretion increases the release of acetyl ...
Nasal Drug Delivery
... because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. The main objective of this thesis was to investigate factors influencing the permeability of the nasal mucosa to various compounds and to evaluate impl ...
... because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. The main objective of this thesis was to investigate factors influencing the permeability of the nasal mucosa to various compounds and to evaluate impl ...
Winter 2013 - Ontario College of Pharmacists
... who meet specific practice requirements are selected to be involved in this program, and was satisfied that the combined degree program will prepare students with the practice skills needed for entry-to-practice. As such, Council approved the practical training program associated with the combined d ...
... who meet specific practice requirements are selected to be involved in this program, and was satisfied that the combined degree program will prepare students with the practice skills needed for entry-to-practice. As such, Council approved the practical training program associated with the combined d ...
Standards for Conscious Sedation in the Provision of Dental Care
... use of appropriate audit tools to review clinical outcomes is an essential component of good clinical practice. Careful and reflective use of such data will enhance patient safety and improve the quality of care. 8. It is recommended that a system for reporting adverse ...
... use of appropriate audit tools to review clinical outcomes is an essential component of good clinical practice. Careful and reflective use of such data will enhance patient safety and improve the quality of care. 8. It is recommended that a system for reporting adverse ...
PRODUCT MONOGRAPH Pilocarpine Hydrochloride Tablets, USP
... Hepatic Impairment: Decreased pilocarpine hydrochloride plasma clearance was observed in patients with mild to moderate hepatic impairment (see ACTIONS AND CLINICAL PHARMACOLOGY). Patients with mild and moderate hepatic impairment should begin treatment at a reduced daily dose, gradually increasing ...
... Hepatic Impairment: Decreased pilocarpine hydrochloride plasma clearance was observed in patients with mild to moderate hepatic impairment (see ACTIONS AND CLINICAL PHARMACOLOGY). Patients with mild and moderate hepatic impairment should begin treatment at a reduced daily dose, gradually increasing ...
New Zealand Practice Guidelines for Opioid Substitution Treatment
... and service sector standards require not only that the principles of the Treaty of Waitangi be expressed in policy but that issues specific to Māori (including the Treaty) also be clearly addressed. ...
... and service sector standards require not only that the principles of the Treaty of Waitangi be expressed in policy but that issues specific to Māori (including the Treaty) also be clearly addressed. ...
New Zealand Practice Guidelines for Opioid
... and service sector standards require not only that the principles of the Treaty of Waitangi be expressed in policy but that issues specific to Māori (including the Treaty) also be clearly addressed. ...
... and service sector standards require not only that the principles of the Treaty of Waitangi be expressed in policy but that issues specific to Māori (including the Treaty) also be clearly addressed. ...
Mapping Polygenes - University of Warwick
... linkage between molecular markers and genes controlling quantitative traits (34, 43, 52, 55, 62). In species where severe inbreeding is tolerated, recombinant inbred populations (derived by inbreeding F2 progeny until they become virtually homozygous lines by selfing or sibbing) have also been used ...
... linkage between molecular markers and genes controlling quantitative traits (34, 43, 52, 55, 62). In species where severe inbreeding is tolerated, recombinant inbred populations (derived by inbreeding F2 progeny until they become virtually homozygous lines by selfing or sibbing) have also been used ...
Botulinum Toxins A and B - UnitedHealthcareOnline.com
... This Drug Policy provides assistance in interpreting UnitedHealthcare benefit plans. When deciding coverage, the member specific benefit plan document must be referenced. The terms of the member specific benefit plan document [e.g., Certificate of Coverage (COC), Schedule of Benefits (SOB), and/or S ...
... This Drug Policy provides assistance in interpreting UnitedHealthcare benefit plans. When deciding coverage, the member specific benefit plan document must be referenced. The terms of the member specific benefit plan document [e.g., Certificate of Coverage (COC), Schedule of Benefits (SOB), and/or S ...
Fourth_amended_complaint_restricted.pdf1165439753581
... EXAMPLES OF SPECIFIC UNLAWFUL CONDUCT ........................................................61 A. ...
... EXAMPLES OF SPECIFIC UNLAWFUL CONDUCT ........................................................61 A. ...
Training Carnitine - Overview
... 9. Molecular diagnosis provides information on the gene for the carnitine transporter defective in PCD, which has been cloned (OCTN2) and can be screened for mutations. 10. Mutation analysis: the genes for most of the enzymes of fatty acid oxidation that are defective in fatty acid oxidation disorde ...
... 9. Molecular diagnosis provides information on the gene for the carnitine transporter defective in PCD, which has been cloned (OCTN2) and can be screened for mutations. 10. Mutation analysis: the genes for most of the enzymes of fatty acid oxidation that are defective in fatty acid oxidation disorde ...
PrCIPRO® XL
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... neuropsychological performance (learning, recall of word lists, visual memory, divided attention) (Müller-Vahl et al., 2003). Physiologic effects: Physiologic effects from dronabinol are quite different from those observed with other psychotomimetics. Pulse rate tends to rise, reduction of saliva pr ...
Allergan to Acquire Naurex - McCormick School of Engineering
... When Naurex first started looking to change that, there was little interest. In 2004, an experiment with ketamine showed it helped depression in 12 of 17 patients who did not respond to other therapies. Naurex chief executive Norbert Riedel, who had been chief scientific officer of Baxter Internati ...
... When Naurex first started looking to change that, there was little interest. In 2004, an experiment with ketamine showed it helped depression in 12 of 17 patients who did not respond to other therapies. Naurex chief executive Norbert Riedel, who had been chief scientific officer of Baxter Internati ...
1.3.1 LEVITRA-Annotated PM dated 06-Mar-2015
... There are no controlled clinical data on the efficacy and safety of LEVITRA in known hereditary degenerative retinal disorders such as retinitis pigmentosa; its use is therefore not recommended until further information is available. Otologic Sudden decrease or loss of hearing has been reported in a ...
... There are no controlled clinical data on the efficacy and safety of LEVITRA in known hereditary degenerative retinal disorders such as retinitis pigmentosa; its use is therefore not recommended until further information is available. Otologic Sudden decrease or loss of hearing has been reported in a ...
Map and Application of States That Require a Prescription for
... Applies to any product that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labe ...
... Applies to any product that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labe ...
Map and Application of States That Require a Prescription for
... Applies to any product that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labe ...
... Applies to any product that contains any quantity of ephedrine, a salt of ephedrine, an optical isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labe ...
Two-Piece Hard Capsules for Pharmaceutical
... Two-piece hard capsules are a well-established dosage form that provides solutions to many of today’s drug delivery requirements and challenges. Widely used in the pharmaceutical and nutritional supplement industries for more than a century, they are a frequently used dosage form for administering b ...
... Two-piece hard capsules are a well-established dosage form that provides solutions to many of today’s drug delivery requirements and challenges. Widely used in the pharmaceutical and nutritional supplement industries for more than a century, they are a frequently used dosage form for administering b ...