Emerging Drug Trends- Salvia Divinorum
... slurred speech, chills, nausea, decreased heart rate, and a lack of coordination. Though the Mazatecs have been using Salvia for centuries, the long-term effects of the herb remain unknown and have not been fully investigated. ...
... slurred speech, chills, nausea, decreased heart rate, and a lack of coordination. Though the Mazatecs have been using Salvia for centuries, the long-term effects of the herb remain unknown and have not been fully investigated. ...
Hair Pigmentation Literature Review James A. Bourland, Ph.D., DABFT
... Hair specimens were analyzed for cocaine, BE, CE, NCOC by LC/MS/MS. Results were compared to drug-users hair and subjects in a controlled dosing study. Findings/Conclusion(s): The effect of hair color was not evaluated. But the discussion stated “With these limited preliminary data, it appea ...
... Hair specimens were analyzed for cocaine, BE, CE, NCOC by LC/MS/MS. Results were compared to drug-users hair and subjects in a controlled dosing study. Findings/Conclusion(s): The effect of hair color was not evaluated. But the discussion stated “With these limited preliminary data, it appea ...
Lipid Formulations of Amphotericin B: Recent Progress and Future
... along with the increasing frequency of fungal infections over the last decade, there has also been an increase in the number of pathogens recognized as causing invasive disease in the immunocompromised host. Non-albicans Candida species, Torulopsis glabrata, Fusarium species, and Trichosporon beigel ...
... along with the increasing frequency of fungal infections over the last decade, there has also been an increase in the number of pathogens recognized as causing invasive disease in the immunocompromised host. Non-albicans Candida species, Torulopsis glabrata, Fusarium species, and Trichosporon beigel ...
Ciclosporin - IARC Monographs
... A non-linear pharmacokinetic behaviour was seen in New Zealand white rabbits injected intravenously. The volume of distribution at steady state increased with increasing dose (Awni & Sawchuk, 1985). The mean half-time after intravenous administration of 15 mglg bw to male New Zealand rabbits was 229 ...
... A non-linear pharmacokinetic behaviour was seen in New Zealand white rabbits injected intravenously. The volume of distribution at steady state increased with increasing dose (Awni & Sawchuk, 1985). The mean half-time after intravenous administration of 15 mglg bw to male New Zealand rabbits was 229 ...
Studies and Comparisons with Placebo
... 25mg and hydrochlorothiazide 25mg, nicardipine 60mg or slow release nifedipine 20mg has an additive antihypertensίve effect. Carvedilol and atenolol at similar doses were equally effective at reducing blood pressure in patients who had previously not responded adequately to hydrochlorothiazide monoî ...
... 25mg and hydrochlorothiazide 25mg, nicardipine 60mg or slow release nifedipine 20mg has an additive antihypertensίve effect. Carvedilol and atenolol at similar doses were equally effective at reducing blood pressure in patients who had previously not responded adequately to hydrochlorothiazide monoî ...
... patients suffered seizures, and was found to be linked to predisposition such as epilepsy, alcohol/drug withdrawal or antidepressant therapy. Conversely, studies in mice found tramadol had some anticonvulsant effect which appeared to be κ-receptor mediated as it was unaffected by the μ-antagonist, n ...
The safety of hydroquinone
... pharmacokinetic parameters were as follows: Tmax for hydroquinone ranged from 0 to 24 hours, Cmax ranged from 2.555 to 8.652 !g/mL, and AUClast ranged from 2.63 to 36.4 !g.h/mL.7,8 Steady state was achieved by day 4. Comparing results from the 2% and 4% hydroquinone preparations, 0.125 g of 2% hydro ...
... pharmacokinetic parameters were as follows: Tmax for hydroquinone ranged from 0 to 24 hours, Cmax ranged from 2.555 to 8.652 !g/mL, and AUClast ranged from 2.63 to 36.4 !g.h/mL.7,8 Steady state was achieved by day 4. Comparing results from the 2% and 4% hydroquinone preparations, 0.125 g of 2% hydro ...
Prescribing Information
... Therapy with ACTOS, like other thiazolidinediones, may result in ovulation in some premenopausal anovulatory women. As a result, these patients may be at an increased risk for pregnancy while taking ACTOS [see Use in Specific Populations (8.1)]. This effect has not been investigated in clinical tria ...
... Therapy with ACTOS, like other thiazolidinediones, may result in ovulation in some premenopausal anovulatory women. As a result, these patients may be at an increased risk for pregnancy while taking ACTOS [see Use in Specific Populations (8.1)]. This effect has not been investigated in clinical tria ...
List of abbreviations - Therapeutic Goods Administration
... options for the treatment of NSCLC. The sponsor considers that Abraxane addresses this unmet need because, in combination with carboplatin, the drug provides evidence of increased effectiveness in the treatment of NSCLC compared with Taxol in combination with carboplatin, and significantly reduces t ...
... options for the treatment of NSCLC. The sponsor considers that Abraxane addresses this unmet need because, in combination with carboplatin, the drug provides evidence of increased effectiveness in the treatment of NSCLC compared with Taxol in combination with carboplatin, and significantly reduces t ...
EFFECTS OF POMEGRANATE JUICE ON HUMAN CYTOCHROME
... pomegranate juice. Therefore, to confirm this hypothesis, the effects of pomegranate juice on the absorption of carbamazepine were tested. The absorption of carbamazepine from various parts of the rat intestine was examined in the presence or absence of pomegranate juice by the in situ closed loop t ...
... pomegranate juice. Therefore, to confirm this hypothesis, the effects of pomegranate juice on the absorption of carbamazepine were tested. The absorption of carbamazepine from various parts of the rat intestine was examined in the presence or absence of pomegranate juice by the in situ closed loop t ...
A - amphetamine
... AURORA BOREALIS - PCP AUTHOR - doctor who writes illegal prescriptions B B - small amount of marijuana B-40 - cigar laced with marijuana and dipped in malt liquor BABE - drug used for detoxification BABY - marijuana BABY BHANG - marijuana BABY HABIT - occasional use of drugs BABYSIT - guide someone ...
... AURORA BOREALIS - PCP AUTHOR - doctor who writes illegal prescriptions B B - small amount of marijuana B-40 - cigar laced with marijuana and dipped in malt liquor BABE - drug used for detoxification BABY - marijuana BABY BHANG - marijuana BABY HABIT - occasional use of drugs BABYSIT - guide someone ...
CHEWING GUM - International Journal of Pharmaceutical Sciences
... advantages to using chewing gum to administer drugs. It is non‐invasive, readily accepted, and can be given at almost any time and everywhere. Stability of the therapeutic agent is easily maintained during storage because of packaging that keeps it away ...
... advantages to using chewing gum to administer drugs. It is non‐invasive, readily accepted, and can be given at almost any time and everywhere. Stability of the therapeutic agent is easily maintained during storage because of packaging that keeps it away ...
Apo-Amoxi
... necessary. Smaller doses than than those those recommended recommended bacteriological and clinical clinical appraisals above should not be used. In stubborn infections, therapy therapy may be required required for several several weeks. It necessary to continue continue clinical clinical and/or and ...
... necessary. Smaller doses than than those those recommended recommended bacteriological and clinical clinical appraisals above should not be used. In stubborn infections, therapy therapy may be required required for several several weeks. It necessary to continue continue clinical clinical and/or and ...
Anaesthesia - University Hospitals Bristol NHS Foundation Trust
... Outreach: Your Outreach Librarian can help facilitate evidence-based practise for all in the oral and maxillofacial surgery team, as well as assisting with academic study and research. We can help with literature searching, obtaining journal articles and books, and setting up individual current awar ...
... Outreach: Your Outreach Librarian can help facilitate evidence-based practise for all in the oral and maxillofacial surgery team, as well as assisting with academic study and research. We can help with literature searching, obtaining journal articles and books, and setting up individual current awar ...
Oxycodone-Naloxone Acino Prolonged
... Theoretically, medicinal products that inhibit CYP2D6 activity, such as paroxetine, fluoxetine and quinidine, may cause decreased clearance of oxycodone which could lead to an increase in oxycodone plasma concentrations. Concomitant administration with CYP2D6 inhibitors had an insignificant effect o ...
... Theoretically, medicinal products that inhibit CYP2D6 activity, such as paroxetine, fluoxetine and quinidine, may cause decreased clearance of oxycodone which could lead to an increase in oxycodone plasma concentrations. Concomitant administration with CYP2D6 inhibitors had an insignificant effect o ...
product monograph - Takeda Canada Inc.
... Several published observational studies suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine. The risk of fracture was increased in patients who received high-dose, defined as multiple daily doses, and long-term PPI therapy ...
... Several published observational studies suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine. The risk of fracture was increased in patients who received high-dose, defined as multiple daily doses, and long-term PPI therapy ...
they look for answers. Men don’t look for excuses.
... In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including VIAGRA) reported a sudden decrease or loss of vision. It is not possible to determine whether these events are related directly to these medicines or to other factors. If you experience sudden decrease or l ...
... In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including VIAGRA) reported a sudden decrease or loss of vision. It is not possible to determine whether these events are related directly to these medicines or to other factors. If you experience sudden decrease or l ...
Fexofast Presentation
... when terfenadine was given at oral doses of up to 300 mg/kg/day throughout organogenesis, which corresponds to levels of systemic fexofenadine exposure fourfold and 32-fold higher, respectively, than those anticipated in clinical use. Decreased pup weight and survival occurred in rats when terfenadi ...
... when terfenadine was given at oral doses of up to 300 mg/kg/day throughout organogenesis, which corresponds to levels of systemic fexofenadine exposure fourfold and 32-fold higher, respectively, than those anticipated in clinical use. Decreased pup weight and survival occurred in rats when terfenadi ...
AusPAR Ledipasvir / Sofosbuvir - Therapeutic Goods Administration
... SOF was absorbed quickly and the peak median plasma concentration was observed ~0.8 to 1 hour post dose. Median peak plasma concentration of the active metabolite of SOF was observed between 3.5 to 4 h post dose. LDV is not significantly metabolised. Following a single dose of 90 mg [14C]-LDV, syste ...
... SOF was absorbed quickly and the peak median plasma concentration was observed ~0.8 to 1 hour post dose. Median peak plasma concentration of the active metabolite of SOF was observed between 3.5 to 4 h post dose. LDV is not significantly metabolised. Following a single dose of 90 mg [14C]-LDV, syste ...
Tetracyclines in malaria | Malaria Journal | Full Text
... protein synthesis and also decrease the activity of a mitochondrial enzyme (i.e., dihydroorotate dehydrogenase) involved in de novo pyrimidine synthesis [32]. Doxycycline inhibits the synthesis of nucleotides and deoxynucleotides in P. falciparum [33], but the concentration used (200 µM) is much hig ...
... protein synthesis and also decrease the activity of a mitochondrial enzyme (i.e., dihydroorotate dehydrogenase) involved in de novo pyrimidine synthesis [32]. Doxycycline inhibits the synthesis of nucleotides and deoxynucleotides in P. falciparum [33], but the concentration used (200 µM) is much hig ...
Genetic Analysis of Variation in Human Meiotic Recombination
... diversity. Given its importance, we would expect the number and location of exchanges to be tightly regulated. However, studies show significant gender and interindividual variation in genome-wide recombination rates. The genetic basis for this variation is poorly understood. In this study, we used ...
... diversity. Given its importance, we would expect the number and location of exchanges to be tightly regulated. However, studies show significant gender and interindividual variation in genome-wide recombination rates. The genetic basis for this variation is poorly understood. In this study, we used ...
CIPRO XL PRODUCT MONOGRAPH
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
annexure – ii
... In this case, improved bioavailability can be achieved by the use of delivery systems, which can enhance the rate and/or the extent of drug solubilizing into aqueous intestinal fluids. Phospholipids play a major role in drug delivery technology. There are numerous advantages of phospholipids in addi ...
... In this case, improved bioavailability can be achieved by the use of delivery systems, which can enhance the rate and/or the extent of drug solubilizing into aqueous intestinal fluids. Phospholipids play a major role in drug delivery technology. There are numerous advantages of phospholipids in addi ...
Spinocerebellar ataxia type 1 (SCA1): Phenotype-genotype
... Sequence analysis revealed that the 14 normal SCA1 alleles with 29 and 30 triplets as well as the alleles with 35 ± 38 triplets are interrupted by the sequence CAT CAG CAT. In alleles with 39 ± 41 triplets the interruption is missing in six of seven cases. DNA sequences are summarised in Table 1. Al ...
... Sequence analysis revealed that the 14 normal SCA1 alleles with 29 and 30 triplets as well as the alleles with 35 ± 38 triplets are interrupted by the sequence CAT CAG CAT. In alleles with 39 ± 41 triplets the interruption is missing in six of seven cases. DNA sequences are summarised in Table 1. Al ...