• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Designer Drug Update - Commonwealth Prevention Alliance
Designer Drug Update - Commonwealth Prevention Alliance

... Desmomorphine - derivative of morphine ...
FACTORS THAT CHANGE DRUG ACTION
FACTORS THAT CHANGE DRUG ACTION

... Males are less susceptible to tricyclic antidepressants. CYP enzymes sensitivity decrease in old age......... Side effects of neuroleptics tardive dyskinesia and succinylcholines myalgia are observed more frequently in women. ...
S0735109712013162_mmc1
S0735109712013162_mmc1

... a 5-7% greater reduction in LDLc with rosuvastatin compared to noncarriers{Bailey, 2010 #1820}. Although a recent GWAS did not identify this variant as a determinant of atorvastatin reduction(8), whether this is due to a failure to replicate or statin-specific effects is unknown. ...
Drugs - Images
Drugs - Images

... Intensity of dependence depends on the nature of the drug. Drugs resulting in high degree of involvement: ...
Drugs Review - Schoolwires
Drugs Review - Schoolwires

... and other mental problems,  The most popular stimulant in the world is not cocaine - it is caffeine. ...
Chapter 1 - Drugs and Agents - Factors Affecting their Action
Chapter 1 - Drugs and Agents - Factors Affecting their Action

... Study of how drugs may best be used in the treatment of illnesses  Study of which drug would be most appropriate or least appropriate to use for a specific disease; what dose would be required; etc. ...
Powerpoint slides
Powerpoint slides

... In behavioural pharmacology we use dose as the Independent variable and response (behaviour) ad the dependent variable Need a control group or control condiiton ...
Psychology 2800 Drugs and Behaviour
Psychology 2800 Drugs and Behaviour

... In behavioural pharmacology we use dose as the Independent variable and response (behaviour) ad the dependent variable Need a control group or control condiiton ...
Pain Management Contract FAQ
Pain Management Contract FAQ

... Answer: New Texas Medical Board rules for pain management went into effect on August 4, 2015. Please see specifically, Rule §170.3, Minimum Requirements for the Treatment of Chronic Pain: (4) Agreement for treatment of chronic pain. A proper patient-physician relationship for treatment of chronic pa ...
MBlackman_AACE_press_conf_051708
MBlackman_AACE_press_conf_051708

Sick Day Medications In the Elderly
Sick Day Medications In the Elderly

... aging causes decreased muscle mass, and increased proportion of body fat, reduction in total body water, less albumin, risk of drug toxicity if distribution volume decreased and loading dose decreased in elderly) ...
More Evolution and Hardy Weinberg! KEY
More Evolution and Hardy Weinberg! KEY

... Decrease in the population due to some environment disaster, genetic drift 3. What is the founder effect? This is an example of which mechanism? Individuals that have been isolated, they evolve based on the environment 4. True or false: Genetic drift can cause allele frequencies to change randomly: ...
BOSENTAN and POSSIBLE DRUG INTERACTIONS (No 1
BOSENTAN and POSSIBLE DRUG INTERACTIONS (No 1

... Background Sitaxentan is metabolised in the liver by Cytochrome P450 (CYP) isoenzymes CYP2C9 (major pathway) and CYP3A4 (minor pathway). Approximately half of an oral dose is excreted in the urine with the remainder eliminated in the faeces. Although there is potential for interaction with CYP2C9 an ...
Genetics Unit: 1. Heredity- the passing of traits from parent to young
Genetics Unit: 1. Heredity- the passing of traits from parent to young

... Genetics- branch of Biology that studies heredity Genes- factors that control traits Genotype- genetic makeup (ex. TT, Tt or tt) Genotypic Ratio- the proportion of genotypes for a particular parental cross Traits- specific characteristics that vary from one individual to the next Alleles- different ...
Chapter 3.Litho
Chapter 3.Litho

... and behaviour and for creating dependence. Although many of them have considerable therapeutic value, they are also widely misused, thereby creating a series of adverse consequences for society. The aim of this chapter is to examine the different kinds of drug which are abused and to consider their ...
Alex W explores the effects of doping on the body
Alex W explores the effects of doping on the body

... Doping: What does it do to you? Doping has become a major problem in sport over the last few years with many athletes using performance-enhancing drugs to help them win a race or match. But do they really know what it does to their bodies? The main problem is that when they are bought without a pres ...
What Tests are Required and When Will I Be Tested?
What Tests are Required and When Will I Be Tested?

... Reporting for duty or remaining on duty to perform a safety-sensitive function with an alcohol concentration of 0.04 or greater; Use during the 8 hours following an accident, or until the driver undergoes a post-accident test; and Refusal to take a required test. ...
Benzodiazepines and risk behaviour
Benzodiazepines and risk behaviour

... Sedative action, side effects drowsiness, dizziness, confusion. Methenamine – antiseptic/antibacterial can cause irritation of stomach or bladder Warfarin – blood thinning medication Amitriptylene - seizures, heart rate,sedation ...
butalbital, acetaminophen, caffeine - DavisPlus
butalbital, acetaminophen, caffeine - DavisPlus

... cause of the habit-forming potential of butalbital. If medication appears less effective after a few weeks, consult health care professional. The dose of acetaminophen should not exceed the maximum recommended daily dose of 4 g/day. Chronic excessive use of ⬎4 g/day (2 g in chronic alcoholism) may l ...
Stáhnout zdroj prezentace
Stáhnout zdroj prezentace

... PMs show large increases in AUC compared to EMs. The high plasma levels increase the frequency of adverse drug reactions (type I) and reduces drug tolerance in PMs. In the Case of METOTPROLOL, PMs are at high risk of hypotension and bradycardia even at normal ‘therapeutic’ doses. ...
CDS User Scenarios
CDS User Scenarios

... was started on 40 mg simvastatin therapy which minimized her out of pocket costs.  Today she feels no different than usual. She would like to get off of her medications which she thinks are causing more harm than good and affect her fixed income budget. She has joint stiffness when she wakes up in ...
AP Psych Lesson 16.6
AP Psych Lesson 16.6

... nervous system ...
Adverse effects
Adverse effects

... -Due to reduced binding at the target site Pharmacokinetics Linezolidis completely absorbed after oral administration. An IV preparation is also available. -The drug is widely distributed throughout the Body -it is metabolized via oxidation to two inactive metabolites. -The drug is excreted both by ...
Adverse Drug Reactions
Adverse Drug Reactions

... 2,000 deaths/year ...
Why do some patients benefit from medications while
Why do some patients benefit from medications while

< 1 ... 1223 1224 1225 1226 1227 1228 1229 1230 1231 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report