• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Variety of Decision Support Systems and Their Implementation
Variety of Decision Support Systems and Their Implementation

... • Patient disease risk score calculation • Screening and clinical visits prioritisation based on patient risk score • Personalised lifestyle management guidelines • Health diary enabling systematic collection of quantified self and fitness data ...
Antidepressant Choices in Primary Care
Antidepressant Choices in Primary Care

... Are all of the antidepressants equally efficacious? This is unlikely given that not all people respond to the same antidepressant trial. Table 1 summarizes the newer antidepressants marketed in the United States and lists their FDA-approved indications and usual dosing ranges. The SSRIs are not inte ...
Sustained Release Formulations
Sustained Release Formulations

... Metabolic conversion of drug to another chemical form. Factors associated with metabolism are; Ability of drug to induce or inhibit enzyme synthesis. This results in fluctuating drug blood level with chronic dosing. Fluctuating drug blood level due to intestinal metabolism or through a hepatic ...
Undergraduate Health	Sciences Pharmacy 1131
Undergraduate Health Sciences Pharmacy 1131

... Non-adherence to medications is a great burden on the United States healthcare system with costs exceeding $300 billion dollars annually. ...
supplementary information
supplementary information

... 45°C using a rotational oven, and washed according to Affymetrix standard protocols using a GC450 Fluidics Station. The Genechips were scanned with an Affymetrix 7G scanner and the CEL files generated were analyzed through Affymetrix Expression Console Software (version 1.3) which normalizes array s ...
Poisoning and OD PPT
Poisoning and OD PPT

... Induces vomiting by irritating stomach and stimulating vomiting center in brainstem ...
AP Biology Jones The components to the Hardy
AP Biology Jones The components to the Hardy

... Trends toward narrow range of phenotype; favors intermediate area of phenotypic range. ...
Overdose - Hatzalah of Miami-Dade
Overdose - Hatzalah of Miami-Dade

... Induces vomiting by irritating stomach and stimulating vomiting center in brainstem ...
Malaria research in the post-genomic era
Malaria research in the post-genomic era

... Analyzing expression pattern in different life cycle stages to predict possible functions ...
pdb-d.eng.uiowa.edu
pdb-d.eng.uiowa.edu

... A series of interconected enzymatic steps linked by the production of intermediates that are used in the next enzymatic step (Note this definition will change) May also include signaling pathways as well were one input may cause several effects ...
BASIC CONCEPTS IN GENETICS
BASIC CONCEPTS IN GENETICS

... • Reciprocal cross a cross, with the phenotype of each sex reversed as compared with the original cross, to test the role of parental sex on inheritance pattern. A pair of crosses of the type genotype A(female) X genotype B(male) and genotype B(female) X genotype A(male). ...
Gene selection: choice of parameters of the GA/KNN method
Gene selection: choice of parameters of the GA/KNN method

... Survival of the fittest principle The single best chromosome from each niche is entered into the respective subsequent niche deterministically The remains are filled according to the relative fitness of the chromosome ...
- Daiichi Sankyo
- Daiichi Sankyo

... President and CEO of Daiichi Sankyo, Inc. “Daiichi Sankyo strives to contribute to the health and wellbeing of people worldwide, particularly in cardiovascular care, and we will continue to investigate new applications of our therapies for patients’ benefit.” A recent survey of physicians attending ...
Drug Benefit Council (DBC) Recommendation and Reasons for
Drug Benefit Council (DBC) Recommendation and Reasons for

... 2) Overall Coverage Recommendation for Adults: Based on the evidence provided, is the current PharmaCare coverage provided by the Ministry for the management of ADHD in adult patients appropriate with regard to clinical efficacy, effectiveness, safety and cost-effectiveness? a) The DBC recommends Ph ...
Gene Flow (migration)
Gene Flow (migration)

... compete for mates by using their antlers to spar against other males, chasing one another and fighting. This is a form of non-random mating because it prevents certain phenotypes from breeding. Only the individuals who successfully mate will contribute to the gene pool of the next generation. - E.g. ...
Genetic Disorder Oral Presentation Requirements
Genetic Disorder Oral Presentation Requirements

... 3. When appropriate, you should or could include a Punnett Square to explain how the genes are passed on to offspring. 4. What chromosome or chromosomes are affected? Are the chromosomes autosomes (chromosomes 1-22) or is the genetic disorder sex-linked (found on the “X” chromosome)? Does the person ...
Fatality From Spasmo-Proxyvon® Addiction: A Few Cases
Fatality From Spasmo-Proxyvon® Addiction: A Few Cases

... CVS collapse and respiratory depression. It is contraindicated in people with narrow iridocorneal angle and prostatic hypertrophy. The normal therapeutic dose is 10-20 mg orally, three or four times a day.4 Acetaminophen (paracetamol) is a para-aminophenol derivative, and is an analgesic- antipyreti ...
Antibodies – The “Magic Bullets” for Drug Delivery?
Antibodies – The “Magic Bullets” for Drug Delivery?

... of disease and “cure” it remains to this day a fantasy, a science fiction. In 2014, I published an article on “Targeting Drug-Delivery Systems: Promises, Promises, and More Promises. Let’s Change the Paradigm” [1], pointing out that over 3,000 publications that appeared in previous 10 years (based o ...
Part Two - West Lakes GP Training
Part Two - West Lakes GP Training

... having inherited the condition from him, Mr P asks the GP to organise a kidney ultrasound for his two children aged 10 and 7, to see if they have inherited the condition. The GP should do so. ...
Uso de Midazolam com oximetria de pulso em pacientes com
Uso de Midazolam com oximetria de pulso em pacientes com

...  Sedative, anxiolytic, anticonvulsant and muscle relaxant properties;  Low toxicity level;  Hepatic metabolized and renal elimination;  Induce a short duration amnesia;  Low cost;  Easy use (oral via, one hour before the dental treatment) Yuan et al., 1999  Flumazenil, a benzodiazepine antago ...
lf you`re fqking rhis drug, don`t eql fhot
lf you`re fqking rhis drug, don`t eql fhot

... coordinoted; when it's mixed with certoin drugs, those effects con be mognified. Even worse, certoin drug-olcohol combos con increose the chonce of serious side effects, such qs internol bleeding, difficulty breothing, ond heori problems. And though olcohol might moke o drug less effective, il con o ...
The results of study on Unoprostone (development code UF-021) for... the 30th Annual Meeting of the Japan Society of Drug...
The results of study on Unoprostone (development code UF-021) for... the 30th Annual Meeting of the Japan Society of Drug...

... concluded that “ethylene oxide gas sterilization did not affect the release rate and unoprostone-content of unoprostone-DDS and the quality of the DDS did not alter after accelerated test, and the elution toxicity of the DDS was low from cell culture experiments.” Unoprostone (development code UF-02 ...
Questions for Review
Questions for Review

... Which of the following statements is FALSE? A. Clinical pharmacokinetics (therapeutic monitoring) is based on the assumption that drug concentrations in the blood are directly related to the drug concentrations at the site of action. B. The therapeutic range is based on the probabilities of achievin ...
Unit 6 Genetics - centralmountainbiology
Unit 6 Genetics - centralmountainbiology

... • Blood type is determined by the presence of a carbohydrate group attached to a protein on the surface of red blood cells. ...
Chromosome Microarray (CMA) Pre-Test Patient
Chromosome Microarray (CMA) Pre-Test Patient

... gain or loss of genetic information.  About half of these imbalances will provide an explanation for  their condition and the remaining half will not provide a clear explanation for their condition; these  are called variants of unknown clinical significance (VUS).  What are the possible CMA results ...
< 1 ... 1014 1015 1016 1017 1018 1019 1020 1021 1022 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report