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PRG Notes 8th December 2015 - The Grange, Greenview and
PRG Notes 8th December 2015 - The Grange, Greenview and

... Workers to update the whiteboard for consultant clinics, especially when they are running behind. A member of the group further commented that GP’s can’t have a fixed time for seeing patients as each patient is different and it will depend on their problem. The second comment was from a patient who ...
Populations evolution
Populations evolution

... 11-4: Hardy-Weinberg Equilibrium p2 + 2pq + q2 = 1 and p + q = 1 p = frequency of the dominant allele  q = frequency of the recessive allele  p2 = % of homozygous dominant individuals  q2 = % of homozygous recessive individuals  2pq = % of heterozygous individuals ...
David K. Stein, M.D. - Jacobi Emergency Medicine
David K. Stein, M.D. - Jacobi Emergency Medicine

... Nebs are given and the patient is somewhat better, but needs steroids before discharge. In addition to the Prednisone she is given Omeprazole which she received 3 years ago when she had an UGI bleed. ...
Summary Notes
Summary Notes

... Jellinek proposed the 4 phases of alcoholism, which has since been generalized to describe dependency on other chemicals as well. These phases may assist the nurse in determining the degree to which chemicals are used. Phase 1 Prealcoholic phase: characterized by social drinking, control over drinki ...
Deliriants (drugs causing delirium)
Deliriants (drugs causing delirium)

... – Antiarrhythmics – Digitalis* – Antihypertensives (b-blockers, methyldopa) Miscellaneous – Skeletal muscle relaxants – Steroids ...
Production process model
Production process model

... PRODUCTION PROCESS MODEL ...
Second-line anti
Second-line anti

... times weekly during the continuation phase, under close monitoring for adverse effects. ...
Make a Monster
Make a Monster

... How are traits passed from parents to offspring? A trait is a characteristic such as color or size that is inherited by an offspring from its parents. The genes that control a trait come in pairs, one gene from each parent. We represent these gene pairs by writing a combination of two capital or low ...
Why are dose adjustments important in patients with liver or kidney
Why are dose adjustments important in patients with liver or kidney

... more slowly (slow metabolizers), possibly leading to more adverse drug reactions. Through genetic testing, it is possible to determine whether a person is a fast or slow metabolizer. Such testing, available for more than 50 medications, is seldom used in clinical practice. What type of dose adjustme ...
Adulterated and misbranded drugs
Adulterated and misbranded drugs

... in terms of weight, measure, or numerical count. 3. If it does not contain any statement, word or other information required by or under authority of this Act to appear on the label so as to render it likely to be read and understood by the ordinary individual under customary conditions of purchase ...
31 34 Matsumoto H, Niimi A, Jinnai M, et al. Association of... Verbanck S, Schuermans D, Vincken W. Inflammation and airway
31 34 Matsumoto H, Niimi A, Jinnai M, et al. Association of... Verbanck S, Schuermans D, Vincken W. Inflammation and airway

... being quite satisfactory, particularly since the use of lipid formulations, which contain phospholipids and cholesterol that have properties similar to those of the natural surfactant [8]. Nebulised LAmB also decreases the risk of drug interactions observed with azoles. It allows higher lung tissue ...
Opioid Facts
Opioid Facts

... Among the compounds that fall within this class are hydrocodone (e.g., Vicodin), oxycodone (e.g., OxyContin—an oral, controlled-release form of the drug), morphine, fentanyl, codeine, and related medications. Morphine and fentanyl are often used to alleviate severe pain, while codeine is used for mi ...
- Houston Livestock Show and Rodeo
- Houston Livestock Show and Rodeo

... or medication is strictly prohibited. Such drugs include, but are not limited to, any diuretic, unapproved growth stimulant or other unapproved medication. Unapproved means not approved by the Food and Drug Administration (FDA) and/or the U.S. Department of Agriculture (USDA) for slaughter animals i ...
Generic Drugs – Consumer Reports Health
Generic Drugs – Consumer Reports Health

... drugs. Ask if one of these generics would work as well as the brand-name drug. For example, there is a class of drugs, called statins, to treat high cholesterol. Some statins come as generics, while others do not. If you take a brand-name statin, ask if one of the generic statins would work for you. ...
in the elderly
in the elderly

... the crowded outpatient services. • The elderly often take OTCs (over-the-counter drugs) about which the doctor is not informed. ...
crowley-genes
crowley-genes

... genes with a priori info ...
21 Schnell Kytril - Lebanese Society of Medical Oncology
21 Schnell Kytril - Lebanese Society of Medical Oncology

...  Ondansetron dosed 2–3 times daily – associated with swallowing problems when patients are nauseated ...
The Genetic Analysis of Quantitative Traits
The Genetic Analysis of Quantitative Traits

... each type of pair (AA, aa etc.) 2. Write phenotypes of each type of relative 3. Compute cross-products of phenotypes of members of type of pair 4. Each cross-product by the corresponding frequency 5. Add the result of “4” across all pair types The answer is the covariance you want (if you have done ...
Genetic Equilibrium - Fall River Public Schools
Genetic Equilibrium - Fall River Public Schools

... Variation of Traits in a Population Biologists use graphs to study the frequency of traits Graphs usually resemble a bell curve Individuals at the ends of the bell curve exhibit extreme variations of the trait Individuals in the bell curve exhibit the typical variations of the trait ...
Unit Summary-Genetics
Unit Summary-Genetics

... generation of offspring (F1) were all tall. When he let the F1 plants self-pollinate, Mendel found that three-fourths of their offspring (F2) were tall and one-fourth of the F2 plants were short. The short trait had reappeared in the second generation (F2). Mendel came to the conclusion that each or ...
Ophthalmology and Eye Diseases Gatifloxacin Ophthalmic Solution
Ophthalmology and Eye Diseases Gatifloxacin Ophthalmic Solution

... A 50 year old male patient was placed on gatifloxacin (I.V. 200  mg once daily) following hospital admission with intermittent fever and lower urinary tract ­symptoms. Renal complications ensued with the patient experiencing muscle pain and weakness. The patient was taken off gatifloxacin and placed ...
optimising drug and device together for novel
optimising drug and device together for novel

... based on data from a safety study conducted in 76 CF patients (38 adults and 38 children) over 28 days.12 The lower Cmax indicates less drug was systemically absorbed which may reduce the potential for undesired ototoxic and nephrotoxic side effects. The shorter inhalation time could help to improve ...
The Practical Nurses Role in Preventing Medication Errors
The Practical Nurses Role in Preventing Medication Errors

... for obtaining drug information on the job. Nursing drug handbooks: contain drug information along with nursing considerations. Physician's Desk Reference (PDR) Contains manufacturer's descriptions (package inserts) which are written using FDA standards, but may be slanted in favor of the drug being ...
Coping with infertility Complex genetic disease Paramedical
Coping with infertility Complex genetic disease Paramedical

... select the variants to be genotyped? Rapidly increasing information of the structural or functional variability within the genome (long range rearrangements, patterns of gene expression) will also affect the interpretation of data. Population isolates like Finland, have been very useful for mapping ...
Introduction - Università degli Studi di Roma "Tor Vergata"
Introduction - Università degli Studi di Roma "Tor Vergata"

... studied in animal models (see articles of Animal models section) by transgenic experiments. These models have provide biological evidence of the “pleiotropic nature” of spermatogenic-related genes. Some of them, affects haematopoiesis, and melanogenesis (c-kit and SCF); germline cell division, oocyt ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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