Circuits in Psychopharmacology
... -l"!"euLQtransmitter pathways form the molecular and anatomical substrates that "tune" neurons with~rcuits. This happens not only at the cortical level but at the level of all the nodes within the network of the various cortical circuits. Psychopharmacologists can rationally target these pathways an ...
... -l"!"euLQtransmitter pathways form the molecular and anatomical substrates that "tune" neurons with~rcuits. This happens not only at the cortical level but at the level of all the nodes within the network of the various cortical circuits. Psychopharmacologists can rationally target these pathways an ...
The Distribution of Chandelier Cell Axon Terminals that Express the
... observed in layer II, followed by layers III, V, VI, and IV. In most cortical areas, the density of GAT-1-ir Ch-terminals was positively correlated with the neuronal density, although a negative correlation was detected in layer III across all cortical areas. These results indicate that there are su ...
... observed in layer II, followed by layers III, V, VI, and IV. In most cortical areas, the density of GAT-1-ir Ch-terminals was positively correlated with the neuronal density, although a negative correlation was detected in layer III across all cortical areas. These results indicate that there are su ...
On the Role of Biophysical Properties of Cortical Neurons in Binding
... Neuroscience is progressing vigorously, and knowledge at different levels of description is rapidly accumulating. To establish relationships between results found at these different levels is one of the central challenges. In this simulation study, we demonstrate how microscopic cellular properties, ...
... Neuroscience is progressing vigorously, and knowledge at different levels of description is rapidly accumulating. To establish relationships between results found at these different levels is one of the central challenges. In this simulation study, we demonstrate how microscopic cellular properties, ...
Joint maps for orientation, eye, and direction preference in a self
... Compared to simpler OR-only LISSOM networks, the model introduced in this paper includes two eyes (to model OD) and multiple LGN sheets with different time-delayed copies of previous input patterns. The time delays model the “lagged” cells recently found in cat LGN that respond to retinal inputs onl ...
... Compared to simpler OR-only LISSOM networks, the model introduced in this paper includes two eyes (to model OD) and multiple LGN sheets with different time-delayed copies of previous input patterns. The time delays model the “lagged” cells recently found in cat LGN that respond to retinal inputs onl ...
The Nervous System: Neural Tissue
... A neuron may innervate (1) other neurons, (2) skeletal muscle fibers, or (3) gland cells. Synapses are shown in boxes for each example. A single neuron would not innervate all three. © 2012 Pearson Education, Inc. ...
... A neuron may innervate (1) other neurons, (2) skeletal muscle fibers, or (3) gland cells. Synapses are shown in boxes for each example. A single neuron would not innervate all three. © 2012 Pearson Education, Inc. ...
Nervous Tissue - Manasquan Public Schools
... - have a single process extending from cell body - always are sensory neurons - originate in embryo as bipolar - during development, axon and dendrite fuse together into a single process - single process divides into two branches a short distance from cell body ...
... - have a single process extending from cell body - always are sensory neurons - originate in embryo as bipolar - during development, axon and dendrite fuse together into a single process - single process divides into two branches a short distance from cell body ...
NETMORPH: A Framework for the Stochastic
... The direction of outgrowth of a growth cone depends on many intracellular and extracellular cues, which may cause large fluctuations in outgrowth directions. The neurite segments from reconstructed neurons indeed show many deviations from a straight line at a range of spatial scales. NETMORPH includ ...
... The direction of outgrowth of a growth cone depends on many intracellular and extracellular cues, which may cause large fluctuations in outgrowth directions. The neurite segments from reconstructed neurons indeed show many deviations from a straight line at a range of spatial scales. NETMORPH includ ...
File
... usually (not always) the Axon terminal. The axon terminals are also called the bouton terminaux or synaptic knob. The synaptic knobs have synaptic vesicles that contain the NT (neurotransmitters). The NT are produced in the body & conducted along the axon (anterograde flow). The NT can be inhibitory ...
... usually (not always) the Axon terminal. The axon terminals are also called the bouton terminaux or synaptic knob. The synaptic knobs have synaptic vesicles that contain the NT (neurotransmitters). The NT are produced in the body & conducted along the axon (anterograde flow). The NT can be inhibitory ...
Cell Assembly Sequences Arising from Spike
... tions were consistent from trial to trial, and the time (sec) elapsed time (sec) model was driven by temporally and spatially unstructured noise I(t); different instances of Figure 1. Time prediction from sequential neural activity in a memory task. A, Average raster over 18 s for a population of no ...
... tions were consistent from trial to trial, and the time (sec) elapsed time (sec) model was driven by temporally and spatially unstructured noise I(t); different instances of Figure 1. Time prediction from sequential neural activity in a memory task. A, Average raster over 18 s for a population of no ...
The Autonomic Nervous System
... 2. organs whose activity increases at rest a. parasympathetic: excitatory b. sympathetic: inhibitory • Exception: sweat glands, piloeroector muscles and most peripheral blood vessels receive only sympathetic inputs ...
... 2. organs whose activity increases at rest a. parasympathetic: excitatory b. sympathetic: inhibitory • Exception: sweat glands, piloeroector muscles and most peripheral blood vessels receive only sympathetic inputs ...
Cholinergic Basal Forebrain Neurons Burst with Theta during
... screw was placed in the frontal bone between the frontal lobes and olfactory bulbs to serve as a reference. After recovery from surgery (2 d), the animals were habituated to the head fixation (6 –9 d). While lying in a Plexiglas box, they were prevented from twisting their bodies but otherwise able ...
... screw was placed in the frontal bone between the frontal lobes and olfactory bulbs to serve as a reference. After recovery from surgery (2 d), the animals were habituated to the head fixation (6 –9 d). While lying in a Plexiglas box, they were prevented from twisting their bodies but otherwise able ...
embj201488977-sup-0010-Suppl
... engagement in CRH neurons. (A) Secretagogin can affect CRH release either indirectly, by affecting the function of key proteins involved in the vesicle formation and cargo along the axons to the median eminence (“vesicle logistics”), or more directly, by Ca2+-dependent modulation of the exocytosis m ...
... engagement in CRH neurons. (A) Secretagogin can affect CRH release either indirectly, by affecting the function of key proteins involved in the vesicle formation and cargo along the axons to the median eminence (“vesicle logistics”), or more directly, by Ca2+-dependent modulation of the exocytosis m ...
Simulation of myelinated neuron with focus on conduction speed
... In this study, we have shown that myelination and dendritic structure are responsible for the occurence of DAP and HAP which are in turn responsible for altered threshold of subsequent action potential. We have quantatatively shown that the threshold is different depending on the timing of subsequen ...
... In this study, we have shown that myelination and dendritic structure are responsible for the occurence of DAP and HAP which are in turn responsible for altered threshold of subsequent action potential. We have quantatatively shown that the threshold is different depending on the timing of subsequen ...
Cholinergic modulation of synaptic properties of cortical layer VI
... might be to enhance the dynamic gain control mechanism previously proposed for the corticothalamic feedback (Lindström and Wróbel 1990, Granseth et al. 2002, Granseth 2004). According to this hypothesis, the enhanced facilitation of corticothalamic input induced by acetylcholine (occurring most prob ...
... might be to enhance the dynamic gain control mechanism previously proposed for the corticothalamic feedback (Lindström and Wróbel 1990, Granseth et al. 2002, Granseth 2004). According to this hypothesis, the enhanced facilitation of corticothalamic input induced by acetylcholine (occurring most prob ...
Presentation materials - Brain Dynamics Laboratory
... • Bursts have higher signal-to-noise ratio than single spikes. Burst threshold is higher than spike threshold, i.e., generation of bursts requires stronger inputs. • Bursts can be used for selective communication if the postsynaptic cells have subthreshold oscillations of membrane potential. Such ce ...
... • Bursts have higher signal-to-noise ratio than single spikes. Burst threshold is higher than spike threshold, i.e., generation of bursts requires stronger inputs. • Bursts can be used for selective communication if the postsynaptic cells have subthreshold oscillations of membrane potential. Such ce ...
Heterogeneity of GABAergic Cells in Cat Visual Cortex
... by performing the first staining sequence, omitting the DAB reaction, following this by the electrophoresis step and a second application of the first staining sequence, but now omitting the primary antiserum. If this results in negative staining, one can be sure that the elution is complete. The in ...
... by performing the first staining sequence, omitting the DAB reaction, following this by the electrophoresis step and a second application of the first staining sequence, but now omitting the primary antiserum. If this results in negative staining, one can be sure that the elution is complete. The in ...
Morphological and Functional Types of Neurons
... acid decarboxylase, the rate-limiting enzyme in the synthesis of GABA (Penny et al., 1983; Spreafico et al., 1983). In the Galago VB, a similar classification of projection neurons and interneurons has been made (Pearson and Haines, 1980). The physiological evidence for submodal-specific groups of c ...
... acid decarboxylase, the rate-limiting enzyme in the synthesis of GABA (Penny et al., 1983; Spreafico et al., 1983). In the Galago VB, a similar classification of projection neurons and interneurons has been made (Pearson and Haines, 1980). The physiological evidence for submodal-specific groups of c ...
neural circuitry approaches to understanding the pathophysiology
... within the gray matter, and a principal axonal projection, which enters the white matter and travels to another brain region. These axons utilize excitatory amino acids, such as glutamate, as a neurotransmitter and form synapses that have the characteristic morphology associated with excitatory neur ...
... within the gray matter, and a principal axonal projection, which enters the white matter and travels to another brain region. These axons utilize excitatory amino acids, such as glutamate, as a neurotransmitter and form synapses that have the characteristic morphology associated with excitatory neur ...
REVIEW OF LIMBIC SYSTEM, HYPOTHALAMUS, THALAMUS
... by exaggerated and exceptionally disagreeable responses to cutaneous stimulation. ...
... by exaggerated and exceptionally disagreeable responses to cutaneous stimulation. ...
Roles for miRNAs in Timing Developmental Progression Within
... dampen endogenous expression of Ab, albeit in a different tissue. Whether or not Ab levels contribute to the muscle defects of let-7C mutants remains to be seen. Altogether, these results suggest that let-7 regulates developmental timing of the neuromuscular system in Drosophila, at least in part, b ...
... dampen endogenous expression of Ab, albeit in a different tissue. Whether or not Ab levels contribute to the muscle defects of let-7C mutants remains to be seen. Altogether, these results suggest that let-7 regulates developmental timing of the neuromuscular system in Drosophila, at least in part, b ...
The W cell pathway to cat primary visual cortex
... total of 231 synaptic boutons from layers 1, 2/3, and 5 (95 from layer 1, 69 from layer 2/3, and 67 from layer 5) in two cats. Almost half (118 boutons) were sectioned serially and completely reconstructed. The remainder (113) were less complete, often single sections, but more if it was necessary t ...
... total of 231 synaptic boutons from layers 1, 2/3, and 5 (95 from layer 1, 69 from layer 2/3, and 67 from layer 5) in two cats. Almost half (118 boutons) were sectioned serially and completely reconstructed. The remainder (113) were less complete, often single sections, but more if it was necessary t ...
The hippocampo-cortical loop: Spatio
... information about the environment (sensory state in EC), or the prediction of this information. In both cases, we build transitions between states which are coded on one neuron (‘‘Transition cell’’, see below). In all our models, neurons are modeled as analog units. However this single neuron activi ...
... information about the environment (sensory state in EC), or the prediction of this information. In both cases, we build transitions between states which are coded on one neuron (‘‘Transition cell’’, see below). In all our models, neurons are modeled as analog units. However this single neuron activi ...
Document
... Schematic drawing showing the 8 transmembrane domain topology of PS1 (blue), APP (yellow) and Notch 1 (red). The endoproteolytic cleavage site of PS1 is indicated bt red arrow and the proposed crucial aspartates (D257 and D385) are indicated by red dots. The intramembranous clevage sites in APP and ...
... Schematic drawing showing the 8 transmembrane domain topology of PS1 (blue), APP (yellow) and Notch 1 (red). The endoproteolytic cleavage site of PS1 is indicated bt red arrow and the proposed crucial aspartates (D257 and D385) are indicated by red dots. The intramembranous clevage sites in APP and ...
Voltage-Sensitive Dye Imaging: Technique review and Models
... resolution (down to 20-50 µm) and high temporal resolution (down to the millisecond). With such resolutions, VSDI appears to be the best technique to study the dynamics of cortical processing at neuronal population level. This invasive technique is also called ”extrinsic optical imaging” because of ...
... resolution (down to 20-50 µm) and high temporal resolution (down to the millisecond). With such resolutions, VSDI appears to be the best technique to study the dynamics of cortical processing at neuronal population level. This invasive technique is also called ”extrinsic optical imaging” because of ...