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A dendritic disinhibitory circuit mechanism for pathway
A dendritic disinhibitory circuit mechanism for pathway

... compartmental neuron with a somatic compartment connected to multiple, otherwise independent, dendritic compartments (only three shown). (b) Excitatory inputs can generate a local, regenerative NMDA plateau potential in the dendrite. As number of activated synapses increased, there is a sharp nonlin ...
Capogna Curr Opin Neurobiol 2014
Capogna Curr Opin Neurobiol 2014

... and synaptic plasticity Few studies have clarified the inputs to BLA GABAergic cells as well as their specialized roles within the network. The PV+ interneurons receive strong excitatory inputs from P-cells of BLA but weak inputs from the cerebral cortex [45] suggesting a main role in feedback inhib ...
The visual cortex - Neuroscience Network Basel
The visual cortex - Neuroscience Network Basel

... The axonal projection from the retina to the brain: Retinal axons form the optic fiber layer of the retina, run up to the optic disk, then form the optic nerve, partly cross in the optic chiasm, then form the optic tract which runs to 1) the lateral geniculate nucleus (lgn), where information is rel ...
lmmunohistochemical Localization
lmmunohistochemical Localization

... was visible on the membrane surface of individual neurons. Cytoplasmic labeling appeared light (Fig. 4A). In some instances, the staining along the surfaces of neuronal cell bodies and dendrites was periodic or punctate in appearance, as is evident on the nonpyramidal CA 1 neuron in Figure 4B. Howev ...
Review (11/01/16)
Review (11/01/16)

... because even though the large-diameter fibers are excitatory and excite the pain pathway, this is countered by the inhibtion that they also activate. • If only small-diameter fibers are activated, inhibitory interneurons are inhibited, which means they do nothing to the pain pathway, so you will exp ...
Modelling the Grid-like Encoding of Visual Space
Modelling the Grid-like Encoding of Visual Space

... observed grid-like firing patterns are presented in section 4. Finally, conclusions reflecting on the results are given in section 5. ...
An oscillation-based model for the neuronal basis
An oscillation-based model for the neuronal basis

... neurons representing all stimulus features and sharing similar receptive fields). Thus, in the presence of multiple stimuli, the neurons responding to the different stimuli will compete against each other. Because we assume that attention “labels” neurons in VI within a particular spatial location, ...
Anatomy Review - Interactive Physiology
Anatomy Review - Interactive Physiology

... a. acetyl choline, postsynaptic neuron b. neurotransmitter, synaptic cleft 36. (Page 8.) The neuron receiving the signal is called the postsynaptic neuron. When activated, receptors on the postsynaptic neuron open ____ _________. a. ion channels b. voltage-gated receptors c. passive channels 37. (Pa ...
Thalamus Notes
Thalamus Notes

... mechanical distortion of deep tissues, or joint rotation, but not to more than one of these. These informations are then integrated in the cortex into perceptions of form, size and texture. The cortical cytoarchitectonic subdivisions of area 3,1,2 differ with regard to the kinds of receptor from whi ...
Anatomy Review
Anatomy Review

... 36. (Page 8.) The neuron receiving the signal is called the postsynaptic neuron. When activated, receptors on the postsynaptic neuron open ____ _________. a. ion channels b. voltage-gated receptors c. passive channels 37. (Page 8.) The movement of ions across the neuronal membrane creates an electri ...
text - Systems Neuroscience Course, MEDS 371, Univ. Conn. Health
text - Systems Neuroscience Course, MEDS 371, Univ. Conn. Health

... Like other regions of the cerebral cortex, V1 is organized into six layers each of which is parallel to the cortical surface (see Purves, pp. 588-589). Together, the layers constitute the cortical grey matter, which is usually about 2 mm in thickness. A. Layer 1, the most superficial layer, contains ...
Gnostic cells in the 21st century
Gnostic cells in the 21st century

... (what it is known as the medial temporal lobe), this procedure is quite successful (Wieser et al. 2001). The success of these surgeries clearly relies on an accurate delineation of the epileptic focus and in some cases, when the evidence about its localization is not conclusive, these patients may b ...
Bi150 (2005)
Bi150 (2005)

... glomus, ball of yarn (Latin) output cells. like a bishop’s miter (hat) Inhibitory ...
Certain Histological and Anatomical Features of the Central Nervous
Certain Histological and Anatomical Features of the Central Nervous

... with fibers of different diameters. The formation of these transverse and longitudinal tracts by fibers arising from discrete groups of nerve cells and their pattern of distribution were reported earlier (Babu, 1965). In the neuropile the course of single large axons of the interneuronal type can be ...
control of movement by the CNS - motor neurons found in anterior
control of movement by the CNS - motor neurons found in anterior

... cells in one column may fire when muscle is active in a specific movement (synergy) same cells may be silent when same muscle participates in a different movement not necessary to represent every possible muscle synergy finite set of cardinal synergies, which can be combined and weighted - coding di ...
Functional and Dysfunctional Aspects of the Cerebral Cortex
Functional and Dysfunctional Aspects of the Cerebral Cortex

... to take care of large receptive fields, reaching the conscious level, and others of small receptive fields for local function at the brainstem level [44]. The strength of information processing performed by a cortical circuit depends on the number of interneuronal connections or synapses. Morphologica ...
Exam I
Exam I

... Match the following parts of a neuron to the best description. (Note: answers can be used more than once or not at all). A) Axon ...
differentiation of neuronal types and synapses in myelinating
differentiation of neuronal types and synapses in myelinating

... palisades. With prolonged maintcnance in vitro these neurons develop some but not all of the features of mature Purkinjc cells. A few small, densely stained, bipolar neurons, often with one process bifurcated, are found in dense regions of some cultures of newborn ccrebcllure. These neurons are comm ...
08 - Pierce College
08 - Pierce College

... d. Sodium-potassium pump 45. Which correctly describes neuron membrane permeability? a. More K+ leaks out than Na+ leaks in b. More Na+ leaks out than K+ leaks in c. K+ and Na+ leak across the membrane, but at equal rates 46. What maintains resting potential? a. K+ leaking in, Na+ leaking out b. K+ ...
Age-dependent effect of cholinergic lesion on dendritic morphology
Age-dependent effect of cholinergic lesion on dendritic morphology

... to young adults [46]. Similarly, the axonal sprouting typically seen in hippocampal neurons following partial deafferentation via lesions of entorhinal cortex is reduced in aged rats [52]. Finally, lesions of the nucleus basalis magnocellularis (NBM) attenuate benzodiazepine-induced potentiation of ...
Long-term channelrhodopsin-2 (ChR2) expression
Long-term channelrhodopsin-2 (ChR2) expression

... (H134R)-EYFP-WPRE, in L2/3 pyramidal cells in rat somatosensory cortex via in utero DNA electroporation (IUE). L2/3 pyramidal cells expressed ChR2-EYFP, but histology revealed abnormal morphology and targeting of ChR2-EYFP expressing axons, beginning at postnatal day (P) 33 and increasing with age. ...
Dendrites as separate compartment – local protein synthesis
Dendrites as separate compartment – local protein synthesis

... group (Gardiol et al. 1999) carried out a solid morphological and immunocytochemical analysis of rat spinal cord neurons. It showed that at the cellular level, in vivo, protein synthesis macrocomplexes (ribosomes and eukaryotic elongation factor-2, eIF-2) as well as the system implicated in cotransl ...
Rearrangement of microtubule polarity orientation during conversion
Rearrangement of microtubule polarity orientation during conversion

... neurons that regenerated an axon from the tip of the dendrite, 84%–100% of microtubules in the mid-region of the original dendrite were plus end-distal (Figs. 3A, 3B, and 3E; Table 1), indicating that microtubule polarity orientation in the original dendrite changed during 24 h of culture. Although ...
The Cochlear Nucleus - Neurobiology of Hearing
The Cochlear Nucleus - Neurobiology of Hearing

... Pathways (afferents and efferents) Cell types Synaptic Circuitries (intrinsic connections) Specialized Synapses Plasticity: deafness and hearing loss ...
Supplementary Information - Gatsby Computational Neuroscience Unit
Supplementary Information - Gatsby Computational Neuroscience Unit

... Note that this LGN model is simplified in several ways. It does not account for the mild orientation bias that has been reported in LGN responses4, for the precise firing statistics and bursting in LGN5,6, or for is the strong temporal correlations that have been observed in LGN responses7. These pr ...
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Apical dendrite

An apical dendrite is a dendrite that emerges from the apex of a pyramidal cell. Apical dendrites are one of two primary categories of dendrites, and they distinguish the pyramidal cells from spiny stellate cells in the cortices. Pyramidal cells are found in the prefrontal cortex, the hippocampus, the entorhinal cortex, the olfactory cortex, and other areas. Dendrite arbors formed by apical dendrites are the means by which synaptic inputs into a cell are integrated. The apical dendrites in these regions contribute significantly to memory, learning, and sensory associations by modulating the excitatory and inhibitory signals received by the pyramidal cells.
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