• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Chapter 48
Chapter 48

Nervous System Notes
Nervous System Notes

... • Saltatory conduction – impulse jumps from 1 node of Ranvier to another; why? • Myelin covering – mostly lipids which prevent flow of ions • channels - are located at nodes of Ranvier for ions to diffuse in & out • Myelinated axons (white matter) - conduct impulses ...
resting potential
resting potential

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
Department of Electrical and Computer Engineering University of
Department of Electrical and Computer Engineering University of

... addition of currents that all follow the same basic rules. Let's now investigate just a few of these different neuronal ionic currents. First, imagine that we have just read Hodgkin and Huxley's series of articles in the Journal of Physiology and are quite impressed, but at the same time are wonderi ...
Receptor Transduction Mechanisms
Receptor Transduction Mechanisms

... which calcium ions can enter the cytoplasm. Changes in membrane potential, as in an action potential, can cause the opening of voltage-dependent calcium channels. Calcium ions flow through the channels from the extracellular space. Agonist binding to some ligand-gated channels, such as the nicotinic ...
EXCITABLE TISSUES
EXCITABLE TISSUES

... and thus differ from voltage gated channels (VOCs). These receptors are  connected  to  cation  channels  for  example  Na+  and  K+  which  allow  these  ions  to  pass  across  the  muscle  membrane  (esp.  Na+,  which  is  driven  by  both concentration and electrical gradients) thus depolarising ...
BIOL 273 Midterm #1 Notes
BIOL 273 Midterm #1 Notes

... The membrane potential of a cell can be changed by either having the potassium concentration gradient changed (so there is an imbalance, and more potassium has to move across to correct this) or having ion permeabilities change (so that other ions can get in on the action, baby!) o ...
Document
Document

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
File
File

... usually (not always) the Axon terminal. The axon terminals are also called the bouton terminaux or synaptic knob. The synaptic knobs have synaptic vesicles that contain the NT (neurotransmitters). The NT are produced in the body & conducted along the axon (anterograde flow). The NT can be inhibitory ...
Principles of Neural Science
Principles of Neural Science

... variation may explain why gap junctions in different tissues are sensitive to different modulatory factors that control their opening and closing. For example, most gap-junction channels close in response to lowered cytoplasmic pH or elevated cytoplasmic Ca2+. These two properties serve to decouple ...
Neurons - Holterman
Neurons - Holterman

... Node of ranvier: allows message to “re-energize” itself. Neuron at rest ...
neurotransmitters
neurotransmitters

Action Potential: Resting State
Action Potential: Resting State

... additional “messages” – Must be removed from its receptor ...
Neurons
Neurons

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
ch 48 nervous system
ch 48 nervous system

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
Neurons
Neurons

... Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Effect of dopamine receptor stimulation on voltage
Effect of dopamine receptor stimulation on voltage

... Impaired working memory is a common feature of neuropsychiatric disorders. It is dependent on control of the medial prefrontal cortex (mPFC) neurons by dopamine. The purpose of this study was to test the effects of a D1/5-type dopamine receptor agonist (SKF 38393, 10 µM) on the membrane potential an ...
9d. Know the functions of the nervous system and the role of
9d. Know the functions of the nervous system and the role of

... • The sympathetic and parasympathetic nervous systems have opposite effects on the same organ system. • These opposing effects help maintain _________________________. ...
Cochlea and Auditory Pathways
Cochlea and Auditory Pathways

... firing and the frequency of their action potentials. Increased volume (amplitude) will result in greater excursion of the basilar membrane, greater displacement of cilia, greater depolarization of receptor cells, and higher frequencies of action potentials in more cochlear nerve axons (whatever the ...
chapt10_holes_lecture_animation
chapt10_holes_lecture_animation

11-1 FUNCTIONS OF THE NERVOUS SYSTEM 1. Sensory input
11-1 FUNCTIONS OF THE NERVOUS SYSTEM 1. Sensory input

... 2. Dendrites are short, cytoplasmic extensions from the neuron cell body. They are specialized to receive stimuli, which can result in the production of an action potential in the neuron. 3. Axons, or nerve fibers, are long cytoplasmic extensions from the neuron cell body. A. The axon arises from a ...
Document
Document

... now Zn2+. [I know this because of my vast knowledge of chemistry ;-)] If we write an overall reaction for this process, we get: Zn + Cu2+  Zn2+ + Cu. This doesn't help us in our quest for electrochemistry knowledge. Let's rewrite this in half-reaction form. ...
11-1 FUNCTIONS OF THE NERVOUS SYSTEM 1. Sensory input
11-1 FUNCTIONS OF THE NERVOUS SYSTEM 1. Sensory input

... B. In the extracellular fluid, the number of plus charges equals the number of minus charges. 3. An electrical charge difference, called a potential difference, exists across the plasma membrane. The potential difference can be measured by placing microelectrodes on either side of the plasma membran ...
chapter 11-nerve tissue
chapter 11-nerve tissue

... a) Chemically-gated channels-open and close in response to certain chemical stimuli. Hormones, neurotransmitters and certain ions can force these channels to open and close. b) Voltage-gated channels-open and close in response to changes in membrane potential. Neurons have sodium and potassium volta ...
Chapter 3 Biological Aspects of Psychology
Chapter 3 Biological Aspects of Psychology

< 1 ... 9 10 11 12 13 14 15 16 17 ... 47 >

Patch clamp



The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells, but is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells. It can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts.The patch clamp technique is a refinement of the voltage clamp. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery made it possible to record the currents of single ion channel molecules for the first time, which improved understanding of the involvement of channels in fundamental cell processes such as action potentials and nerve activity. Neher and Sakmann received the Nobel Prize in Physiology or Medicine in 1991 for this work.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report