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Resting membrane potential is
Resting membrane potential is

... • If two graded potentials occur at the same time in close enough /same places, their effects add up. This is called ...
No Slide Title
No Slide Title

... reflex may not be produced, however if several small pinches are rapidly applied they trigger a reflex.  This is called temporal summation. ...
Orexin-A excites rat lateral vestibular nucleus neurons and improves
Orexin-A excites rat lateral vestibular nucleus neurons and improves

... Orexin is a newly discovered peptide which is synthesized exclusively within the lateral hypothalamic area and perifornical area. Lack of orexin neurons causes narcolepsy-cataplexy, which is characterized by excessive daytime sleepiness, premature transitions to REM sleep, and sudden skeletal muscle ...
Membrane potential synchrony of simultaneously recorded striatal
Membrane potential synchrony of simultaneously recorded striatal

... functionally de®ned region will be synchronous because they depend on the total number of active excitatory inputs. The moment-to-moment variations of membrane potential are generally not synchronous on the time scale of a few milliseconds, as can be seen in Fig. 3b. This could result from activatio ...
File
File

... 1.The difference in potential between the areas. The greater the difference in potential, the greater the current flow. 2.The strength of stimuli: the stronger the strength, the greater the current flow. 3.Local potential: Local potential produced in response to several stimuli is larger than one pr ...
12-4 Membrane Potential
12-4 Membrane Potential

... o The sodium–potassium exchange pump ejects 3 Na+ ions for every 2 K+ ions that it brings into the cell  It serves to stabilize the resting potential when the ratio of Na + entry to K+ loss through passive channels is 3:2 o At the normal resting potential, these passive and active mechanisms are in ...
electrochemistry - einstein classes
electrochemistry - einstein classes

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A. What is a neuron? 1. A neuron is a type of cell that receives and
A. What is a neuron? 1. A neuron is a type of cell that receives and

... 2. Concentration gradient (difference in distribution of ions between the inside and the outside of the membrane): During the resting potential, a difference in the distribution of ions is established with sodium (Na+) 10 times more concentrated outside the membrane than inside and potassium (K+) 2 ...
To Be or Not to Be … an Inhibitory Neurotransmitter
To Be or Not to Be … an Inhibitory Neurotransmitter

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action potential — epilepsy
action potential — epilepsy

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The neuron Label the following terms: Soma Axon terminal Axon
The neuron Label the following terms: Soma Axon terminal Axon

half-reactions - Clayton State University
half-reactions - Clayton State University

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Electrophysiological recordings from behaving animals—going

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ciliated mucous membrane

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AP Electrochemistry Class Packet Unit 10

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Lecture 1 st week

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Redox Reactions and Electrochemistry
Redox Reactions and Electrochemistry

... •  But the voltage for producing O2(g) from solution is considerably higher than the standard potential, because of the high activation energy needed to form O2(g). •  The voltage for this half cell seems to be closer to –1.5 V in reality. •  The result then is the production of Cl2(g) and Cu(s). an ...
Neurons - Cloudfront.net
Neurons - Cloudfront.net

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Forea Wang

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Name Nervous System Questions 1. When a neuron is at its resting
Name Nervous System Questions 1. When a neuron is at its resting

... A. The change in charge difference across the membrane spreads from open potassium channels, causing sodium channels farther along the axon to open. B. The axon returns to its resting potential. C. The change in charge difference across the membrane spreads from open sodium channels, causing sodium ...
A comparision of Hodgkin-Huxley and soliton neural theories
A comparision of Hodgkin-Huxley and soliton neural theories

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Unit 1 – Nervous and Endocrine System
Unit 1 – Nervous and Endocrine System

...  Reflexes are fast b/c the brain does not have to process incoming info before reacting  A reflex arc is the neural pathway that mediates a reflex action  A reflex arc uses very few neurons to transmit messages  Steps in a reflex arc: 1. Receptors (heat, pain, cold) initiate an impulse in a sens ...
Chapter 48
Chapter 48

... 6. How is an action potential (nerve impulse) created? 7. Why does an action potential only travel in 1 direction? 8. How does a neuron communicate with another cell? 9. How does a single neuron interpret multiple inputs? 10. Let’s look at some neurotransmitters…. 11. How is the nervous system organ ...
UNIT 4 – HOMEOSTASIS 8.1 – Human Body Systems and H
UNIT 4 – HOMEOSTASIS 8.1 – Human Body Systems and H

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Nervous System - An-Najah Staff - An
Nervous System - An-Najah Staff - An

... local graded potentials called excitatory postsynaptic potential (EPSPs), caused by the opening of channels that allow simultaneous passage of Na+ and K+. • Neurotransmitter binding at inhibitory chemical synapses results in hyperpolarizations called inhibitory postsynaptic potential (IPSPs), caused ...
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Patch clamp



The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells, but is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells. It can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts.The patch clamp technique is a refinement of the voltage clamp. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery made it possible to record the currents of single ion channel molecules for the first time, which improved understanding of the involvement of channels in fundamental cell processes such as action potentials and nerve activity. Neher and Sakmann received the Nobel Prize in Physiology or Medicine in 1991 for this work.
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