министерство здравоохранения республики беларусь
... weak agonist weak agonist agonist agonist agonist agonist agonist agonist weak agonist antagonist or partial agonist Partial agonist-antagonists partial agonist partial agonist agonist antagonist antagonist or partial agonist ...
... weak agonist weak agonist agonist agonist agonist agonist agonist agonist weak agonist antagonist or partial agonist Partial agonist-antagonists partial agonist partial agonist agonist antagonist antagonist or partial agonist ...
Targeting apicoplasts in malaria parasites
... are significant opportunities to use compounds identified in other systems as treatments for malaria. Somewhat surprisingly, given the many years since inhibition of apicoplast, isoprenoid precursor synthesis proved to be a useful malaria treatment, there are little published data on the downstream ...
... are significant opportunities to use compounds identified in other systems as treatments for malaria. Somewhat surprisingly, given the many years since inhibition of apicoplast, isoprenoid precursor synthesis proved to be a useful malaria treatment, there are little published data on the downstream ...
Benazepril to lisinopril conversion
... Dysfunction Symptoms treatment of prostate cancer may cause impotence (erectile dysfunction or ED). Media Training. Our comprehensive, customized and effective training techniques were developed by founder-president George Merlis and are informed by his career in. Benazepril, brand name Lotensin, is ...
... Dysfunction Symptoms treatment of prostate cancer may cause impotence (erectile dysfunction or ED). Media Training. Our comprehensive, customized and effective training techniques were developed by founder-president George Merlis and are informed by his career in. Benazepril, brand name Lotensin, is ...
Universidade de Lisboa Faculdade de Farmácia Assessing drug
... patience and understanding. I would like to thank Prof. Gert Laekeman, with whom I have had the pleasure of sharing the research period for the European Doctorate, for his valuable guidance and advice, and for welcoming me in Leuven University. Amongst my fellow postgraduate students, I am very grat ...
... patience and understanding. I would like to thank Prof. Gert Laekeman, with whom I have had the pleasure of sharing the research period for the European Doctorate, for his valuable guidance and advice, and for welcoming me in Leuven University. Amongst my fellow postgraduate students, I am very grat ...
Inhibition of Smooth Muscle Cells Proliferation Using Sirolimus
... Statement of Purpose: Drug Eluting Stents (DES) are significantly popular for reducing in-stent restenosis (ISR) as compared to bare metal stents.1 However, their long term efficacy remains a problem, mainly because of late-stent thrombosis and delayed endothelialization.2 The objective of this proj ...
... Statement of Purpose: Drug Eluting Stents (DES) are significantly popular for reducing in-stent restenosis (ISR) as compared to bare metal stents.1 However, their long term efficacy remains a problem, mainly because of late-stent thrombosis and delayed endothelialization.2 The objective of this proj ...
Note for Guidance on Pk in renal impairment
... impairment is likely to significantly alter the pharmacokinetics of the drug and/or its active metabolites and a posology adjustment may be needed for such patients taking into account the PK/PD relationship. Pharmacokinetic characterisation in patients with severe renal impairment should be conside ...
... impairment is likely to significantly alter the pharmacokinetics of the drug and/or its active metabolites and a posology adjustment may be needed for such patients taking into account the PK/PD relationship. Pharmacokinetic characterisation in patients with severe renal impairment should be conside ...
Eco-directed sustainable prescribing
... consumer medications. These are end-of-pipe approaches, which for decades have been the hallmarks for controlling chemical contamination of the environment. These are not, however, approaches that can be relied upon to facilitate the sustainable use of medications. To the contrary, an argument may e ...
... consumer medications. These are end-of-pipe approaches, which for decades have been the hallmarks for controlling chemical contamination of the environment. These are not, however, approaches that can be relied upon to facilitate the sustainable use of medications. To the contrary, an argument may e ...
Preview the material
... Triazolam, because of its short half-life of approximately 2½ hours, is most beneficial for people who have difficulties with sleep onset, rather than with maintaining lasting sleep. Additionally, its short half-life reduces the incidences of residual effects and most people do not develop daytime s ...
... Triazolam, because of its short half-life of approximately 2½ hours, is most beneficial for people who have difficulties with sleep onset, rather than with maintaining lasting sleep. Additionally, its short half-life reduces the incidences of residual effects and most people do not develop daytime s ...
Document
... and asthenia) were reported for 1 subject, in the RTV group on day 1 and resolved the same day without treatment. In cohort 2, treatment-emergent AEs were reported for 7 of 18 subjects (38.9%) receiving COBI. AEs were predominantly grade 1 or grade 2; there were no grade 3 or grade 4 AEs or SAEs. Th ...
... and asthenia) were reported for 1 subject, in the RTV group on day 1 and resolved the same day without treatment. In cohort 2, treatment-emergent AEs were reported for 7 of 18 subjects (38.9%) receiving COBI. AEs were predominantly grade 1 or grade 2; there were no grade 3 or grade 4 AEs or SAEs. Th ...
presentation source
... needs to be used cautiously because it lowers blood pressure. • Viagra should not be given to patients who are taking nitrates, because nitrates are also a strong vasodilator. The use of both could cause major heart problems. • Also, the use of CYP3A4 or P450 inhibitors (which are the cytochromes re ...
... needs to be used cautiously because it lowers blood pressure. • Viagra should not be given to patients who are taking nitrates, because nitrates are also a strong vasodilator. The use of both could cause major heart problems. • Also, the use of CYP3A4 or P450 inhibitors (which are the cytochromes re ...
Guideline on Inhalational medicinal products
... sizes, a bracketing and/or matrixing design may be used to limit the number of test samples necessary. Justification should be provided. Sufficient data should be provided to support the specifications proposed or to give adequate assurance that those performance characteristics which may not be rou ...
... sizes, a bracketing and/or matrixing design may be used to limit the number of test samples necessary. Justification should be provided. Sufficient data should be provided to support the specifications proposed or to give adequate assurance that those performance characteristics which may not be rou ...
Pharmaceutical Blister Packaging, Part I
... an opened bottle of pills has been stored under these conditions, the unused pills will never be the same. Blister packaging, however, keeps each tablet or capsule hermetically sealed in its own bubble. Drugs that are not taken remain in the original package and are fully protected against external ...
... an opened bottle of pills has been stored under these conditions, the unused pills will never be the same. Blister packaging, however, keeps each tablet or capsule hermetically sealed in its own bubble. Drugs that are not taken remain in the original package and are fully protected against external ...
Meperidine - Home - KSU Faculty Member websites
... • Meperidine or pethidine is a narcotic analgesic Introduced in the 1930s, it produces effects that are similar, but not identical, to morphine (shorter duration of action and reduced antitussive and antidiarrheal actions). ...
... • Meperidine or pethidine is a narcotic analgesic Introduced in the 1930s, it produces effects that are similar, but not identical, to morphine (shorter duration of action and reduced antitussive and antidiarrheal actions). ...
The effective study of aqueous extract of Crocus sativus Linn
... epilepsy, chronic diseases such as asthma and arthritis, depressant, cold and coughs. Ayurvedic medicines containing saffron are used to treat acne and several skin diseases. A paste of the spice can be used as a dressing for bruises and superficial sores. Ancient texts on Ayurveda have information ...
... epilepsy, chronic diseases such as asthma and arthritis, depressant, cold and coughs. Ayurvedic medicines containing saffron are used to treat acne and several skin diseases. A paste of the spice can be used as a dressing for bruises and superficial sores. Ancient texts on Ayurveda have information ...
piracetam and platelets
... pharmacotherapy in patients with cerebral disorders is also a matter of speculation (20,21,22). First trials were started in the 1940s and concerned various agents in various neurological disorders (23,24,25). Since piracetam improves learning and memory, Kessler et al. investigated in a double-blin ...
... pharmacotherapy in patients with cerebral disorders is also a matter of speculation (20,21,22). First trials were started in the 1940s and concerned various agents in various neurological disorders (23,24,25). Since piracetam improves learning and memory, Kessler et al. investigated in a double-blin ...
- Nottingham ePrints
... In an appetitively motivated procedure, we have previously reported that systemic treatment with the dopamine (DA) D1 receptor agonist SKF81297 (0.4 and 0.8 mg/kg) depressed acquisition at a 2 s inter-stimulus-interval (ISI), suitable to detect trace conditioning impairment. However since DA is invo ...
... In an appetitively motivated procedure, we have previously reported that systemic treatment with the dopamine (DA) D1 receptor agonist SKF81297 (0.4 and 0.8 mg/kg) depressed acquisition at a 2 s inter-stimulus-interval (ISI), suitable to detect trace conditioning impairment. However since DA is invo ...
Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients
... Clinical trial: This study is registered at clinicaltrials.gov with identifier number NCT01521364. Support statement: This study was financially supported by Stichting Beatrixoord Noord-Nederland (Groningen, The Netherlands). Conflict of interest: Disclosures can be found alongside the online versio ...
... Clinical trial: This study is registered at clinicaltrials.gov with identifier number NCT01521364. Support statement: This study was financially supported by Stichting Beatrixoord Noord-Nederland (Groningen, The Netherlands). Conflict of interest: Disclosures can be found alongside the online versio ...
new zealand data sheet
... evidence suggests that where this occurs it is rarely of significant magnitude. Similarly, although Phenobarbital induces the metabolism of phenytoin it is also, as stated, a competitive inhibitor and in practice, the two effects appear to balance out, with rarely any need for dose adjustment. Howev ...
... evidence suggests that where this occurs it is rarely of significant magnitude. Similarly, although Phenobarbital induces the metabolism of phenytoin it is also, as stated, a competitive inhibitor and in practice, the two effects appear to balance out, with rarely any need for dose adjustment. Howev ...
G6PD deficiency: a classic example of pharmacogenetics with
... favism (Sansone & Segni, 1958), an acute syndrome associated with anaemia, haemoglobinuria and jaundice, potentially fatal especially in children, intriguingly affecting only some of the many people who eat fava beans. Favism had been known for centuries (Fermi & Martinetti, 1905), but it had been m ...
... favism (Sansone & Segni, 1958), an acute syndrome associated with anaemia, haemoglobinuria and jaundice, potentially fatal especially in children, intriguingly affecting only some of the many people who eat fava beans. Favism had been known for centuries (Fermi & Martinetti, 1905), but it had been m ...
Acetaminophen: Old drug, new warnings
... narcotic pain relievers (Table 1).1 This drug is generally considered safe, but high doses can be toxic. The number of overdoses is worrisome. In 2006 alone, the American Association of Poison Control Centers implicated acetaminophen in nearly 140,000 poisoning cases, in which more than 100 patien ...
... narcotic pain relievers (Table 1).1 This drug is generally considered safe, but high doses can be toxic. The number of overdoses is worrisome. In 2006 alone, the American Association of Poison Control Centers implicated acetaminophen in nearly 140,000 poisoning cases, in which more than 100 patien ...
Anabolic Steroids: Lets Get the Facts Right
... injectable or tablet form. Most anabolic steroid tablets present definite risks of permanent liver damage and liver cancer. It is not safe to share needles with any drug. If you inject anabolic steroids and share needles, you are at risk of getting blood transmitted infections such as hepatitis B, h ...
... injectable or tablet form. Most anabolic steroid tablets present definite risks of permanent liver damage and liver cancer. It is not safe to share needles with any drug. If you inject anabolic steroids and share needles, you are at risk of getting blood transmitted infections such as hepatitis B, h ...
COMPARATIVE EVALUATION OF NATURAL AND SYNTHETIC SUPERDISINTEGRANT FOR PROMOTING NIMESULIDE DISSOLUTION FOR FAST DISSOLVING TECHNOLOGY
... acidic nonsteroidal anti‐inflammatory drug falls under BCS class II drug , is selected as a model drug as it is widely used in the treatment of the management of a variety of painful and inflammatory conditions like post operative pain, primary dysmenorrhea ...
... acidic nonsteroidal anti‐inflammatory drug falls under BCS class II drug , is selected as a model drug as it is widely used in the treatment of the management of a variety of painful and inflammatory conditions like post operative pain, primary dysmenorrhea ...
Carisoprodol: an underrecognized drug of abuse in north India
... i.e., 1–3 tablets (each tablet of 350 mg), general relaxation and drowsiness; 4–10 tablets, hypomania and N10 tablets, acute organic brain syndrome-like state. Resultantly it is schedule IV controlled substance in several European countries [25,26] and since January 2012 in the US, too; but in India ...
... i.e., 1–3 tablets (each tablet of 350 mg), general relaxation and drowsiness; 4–10 tablets, hypomania and N10 tablets, acute organic brain syndrome-like state. Resultantly it is schedule IV controlled substance in several European countries [25,26] and since January 2012 in the US, too; but in India ...
17
... Moreover, the branched structures of dendrimers may also impede their passage through small pores, such as those of the glomerular filtration barrier, and, thus, a dendrimer may be eliminated more slowly than a linear polymer with the same molar mass (12–14). Despite these significant potential bene ...
... Moreover, the branched structures of dendrimers may also impede their passage through small pores, such as those of the glomerular filtration barrier, and, thus, a dendrimer may be eliminated more slowly than a linear polymer with the same molar mass (12–14). Despite these significant potential bene ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.