BioFiles v7 n5 - Sigma
... widely prescribed medicine.5 The U.S. Food and Drug Administration (FDA) has approved 10 ACE inhibitors for the treatment of hypertension and there are 15 ACE inhibitors approved worldwide. Sigma® Life Science offers you all 15 approved ACE inhibitors at competitive prices. We strive to provide you ...
... widely prescribed medicine.5 The U.S. Food and Drug Administration (FDA) has approved 10 ACE inhibitors for the treatment of hypertension and there are 15 ACE inhibitors approved worldwide. Sigma® Life Science offers you all 15 approved ACE inhibitors at competitive prices. We strive to provide you ...
Updated US Public Health Service Guidelines for the Management
... occupational exposure to blood and/or other body fluids that might contain human immunodeficiency virus (HIV). Although the principles of exposure management remain unchanged, recommended HIV postexposure prophylaxis (PEP) regimens and the duration of HIV followup testing for exposed personnel have ...
... occupational exposure to blood and/or other body fluids that might contain human immunodeficiency virus (HIV). Although the principles of exposure management remain unchanged, recommended HIV postexposure prophylaxis (PEP) regimens and the duration of HIV followup testing for exposed personnel have ...
Stimulant and Cocaine Psychosis
... Stimulates the sympathetic branch of the autonomic nervous system (Sympathomimetic) • The stimulant and thermogenic effects of Ephedra sinica and other Ephedra species are due to the presence of the alkaloids ephedrine and pseudoephedrine. These compounds stimulate the brain, increase heart rate, ...
... Stimulates the sympathetic branch of the autonomic nervous system (Sympathomimetic) • The stimulant and thermogenic effects of Ephedra sinica and other Ephedra species are due to the presence of the alkaloids ephedrine and pseudoephedrine. These compounds stimulate the brain, increase heart rate, ...
HYDROPHILIC POLYMERS FOR DISSOLUTION ENHANCEMENT OF CELECOXIB Research Article PROF.M.V.NAGABHUSHANAM
... cyclooxygenase-2 (COX-2) and at therapeutic concentrations in humans, celecoxib does not inhibit the cyclooxygenase-1 (COX-1) isoenzyme. Celecoxib is absorbed slowly from the gastrointestinal tract, peak plasma concentrations (4) being achieved approximately 4hrs after an oral dose. Most of the NSAI ...
... cyclooxygenase-2 (COX-2) and at therapeutic concentrations in humans, celecoxib does not inhibit the cyclooxygenase-1 (COX-1) isoenzyme. Celecoxib is absorbed slowly from the gastrointestinal tract, peak plasma concentrations (4) being achieved approximately 4hrs after an oral dose. Most of the NSAI ...
NCPDP Recommendations and Guidance for Standardizing the Dosing Designations on
... This document is Copyright © 2014 by the National Council for Prescription Drug Programs (NCPDP). It may be freely redistributed in its entirety provided that this copyright notice is not removed. It may not be sold for profit or used in commercial documents without the written permission of the cop ...
... This document is Copyright © 2014 by the National Council for Prescription Drug Programs (NCPDP). It may be freely redistributed in its entirety provided that this copyright notice is not removed. It may not be sold for profit or used in commercial documents without the written permission of the cop ...
Quinine toxicity identified after 40 years
... because her vision partially improved after several days. After that episode, she had no significant visual problems except for nyctolopia. She sought medical advice at this time since her visual acuity had further decreased during the past year. Her past health was unremarkable except for the recen ...
... because her vision partially improved after several days. After that episode, she had no significant visual problems except for nyctolopia. She sought medical advice at this time since her visual acuity had further decreased during the past year. Her past health was unremarkable except for the recen ...
Coaated stents: a new era
... "Thiazide-type diuretics should be used as initial therapy in most patients with hypertension, either alone or in combination." JNC 7 "The major classes of hypertensive agents--diuretics, beta blockers, calcium antagonists, ACE inhibitors, ARBs--are suitable for initiation and maintenance of therapy ...
... "Thiazide-type diuretics should be used as initial therapy in most patients with hypertension, either alone or in combination." JNC 7 "The major classes of hypertensive agents--diuretics, beta blockers, calcium antagonists, ACE inhibitors, ARBs--are suitable for initiation and maintenance of therapy ...
Opioid Handout - Oral Surgery Albuquerque NM
... 2. Dentists who prescribe opioids for treatment of dental pain are encouraged to be mindful of and have respect for their inherent abuse potential. 3. Dentists who prescribe opioids for treatment of dental pain are also encouraged to periodically review their compliance with Drug Enforcement Adminis ...
... 2. Dentists who prescribe opioids for treatment of dental pain are encouraged to be mindful of and have respect for their inherent abuse potential. 3. Dentists who prescribe opioids for treatment of dental pain are also encouraged to periodically review their compliance with Drug Enforcement Adminis ...
Early phase PET research in the UK
... research use in developing new drugs. A number of new (i.e. non-FDG) PET tracers have been developed, including radiolabelled anti-cancer drugs, cell receptors and probes for biochemical pathways involved in glucose metabolism, proliferation, apoptosis, hypoxia, and angiogenesis. Together these form ...
... research use in developing new drugs. A number of new (i.e. non-FDG) PET tracers have been developed, including radiolabelled anti-cancer drugs, cell receptors and probes for biochemical pathways involved in glucose metabolism, proliferation, apoptosis, hypoxia, and angiogenesis. Together these form ...
Comparison of uterotonic effects of three low dose oxytocin
... All over the world widely varying regimens of oxytocin are being used to prevent blood loss among parturient mothers during caesarean section. The mechanism of action of these regimens also differs; bolus causes constriction of venous sinuses, leading to placental separation and placental bed haemos ...
... All over the world widely varying regimens of oxytocin are being used to prevent blood loss among parturient mothers during caesarean section. The mechanism of action of these regimens also differs; bolus causes constriction of venous sinuses, leading to placental separation and placental bed haemos ...
Xolair® (Omalizumab) - UnitedHealthcareOnline.com
... reviewers found no difference in the rates of cancer between those patients being treated with Xolair and those who were not being treated with Xolair. However, due to limitations in the 5-year study, FDA cannot rule out a potential risk of cancer with Xolair, so this information was added to the Wa ...
... reviewers found no difference in the rates of cancer between those patients being treated with Xolair and those who were not being treated with Xolair. However, due to limitations in the 5-year study, FDA cannot rule out a potential risk of cancer with Xolair, so this information was added to the Wa ...
adderall xr - Shire Canada
... Amphetamines have a potential for abuse, misuse, dependence, or diversion for non-therapeutic uses that physicians should consider when prescribing this product( see PRECAUTIONS, Dependence Liability.) The misuse of amphetamines may cause serious cardiovascular adverse events and sudden death. Pre-e ...
... Amphetamines have a potential for abuse, misuse, dependence, or diversion for non-therapeutic uses that physicians should consider when prescribing this product( see PRECAUTIONS, Dependence Liability.) The misuse of amphetamines may cause serious cardiovascular adverse events and sudden death. Pre-e ...
S F R SAMHSA
... without producing significant signs of withdrawal (Vocci, Acri et al., 2005). Safety. The high-affinity blockade imposed by buprenorphine significantly limits the effects of subsequently administered opioid agonists or antagonists, and the “ceiling effect” appears to confer a high safety profile, a ...
... without producing significant signs of withdrawal (Vocci, Acri et al., 2005). Safety. The high-affinity blockade imposed by buprenorphine significantly limits the effects of subsequently administered opioid agonists or antagonists, and the “ceiling effect” appears to confer a high safety profile, a ...
Volume 50 Number 1
... Katerina Akassoglou, Ph.D., Assistant Professor of Pharmacology at the University of California at San Diego, is the recipient of the 2008 John J. Abel Award, sponsored by Eli Lilly & Co. The Award is given to a single young investigator for original, outstanding research contributions in the field ...
... Katerina Akassoglou, Ph.D., Assistant Professor of Pharmacology at the University of California at San Diego, is the recipient of the 2008 John J. Abel Award, sponsored by Eli Lilly & Co. The Award is given to a single young investigator for original, outstanding research contributions in the field ...
Plasma Pharmacokinetics of Adriamycin and
... Table 2 shows the total body clearance and steady-state consists of a very rapid decline in plasma Adriamycin concentra tions. Initial concentrations are 50-fold higher than those ob volume of distribution of Adriamycin and the AUC of adriamycinol and Adriamycin for the 2 groups. Similar values were ...
... Table 2 shows the total body clearance and steady-state consists of a very rapid decline in plasma Adriamycin concentra tions. Initial concentrations are 50-fold higher than those ob volume of distribution of Adriamycin and the AUC of adriamycinol and Adriamycin for the 2 groups. Similar values were ...
the selection and use of essential medicines
... and Standards, and Secretary of the Expert Committee, also welcomed the participants. He noted that this would be the third Expert Committee operating under the new procedures approved in 2002. The full effect of these new procedures was now apparent in the careful and timely presentation of evidenc ...
... and Standards, and Secretary of the Expert Committee, also welcomed the participants. He noted that this would be the third Expert Committee operating under the new procedures approved in 2002. The full effect of these new procedures was now apparent in the careful and timely presentation of evidenc ...
Daptomycyin Review
... Gram-positive bacteria are an important cause of serious infections, particularly those originating in hospitals, and are becoming increasingly resistant to many antibiotics hitherto regarded as standard therapy for these infections.1 Daptomycin is an investigational antibiotic that kills most clini ...
... Gram-positive bacteria are an important cause of serious infections, particularly those originating in hospitals, and are becoming increasingly resistant to many antibiotics hitherto regarded as standard therapy for these infections.1 Daptomycin is an investigational antibiotic that kills most clini ...
NATURAL AND PARTIALLY SYNTETIc ANALGESIcS
... Jelena Zivanov-Curlis1 and Stevan Glogovac2 Humans have a long hystory of stimulating and mind-altering substances use. Depressive drugs, including morphine and other narcotics, barbiturates and ethanol, are strongly addictive for susceptible individuals. The phenomenon is most striking in the case ...
... Jelena Zivanov-Curlis1 and Stevan Glogovac2 Humans have a long hystory of stimulating and mind-altering substances use. Depressive drugs, including morphine and other narcotics, barbiturates and ethanol, are strongly addictive for susceptible individuals. The phenomenon is most striking in the case ...
micronization and dissolution enhancement of norethindrone
... minutes and this led an impetus to search for an appropriate formulation that can give better dissolution profile. Mechanical methods of micronization are simple, efficient and cost effective way of achieving particle size reduction. The formulation developed using micronized Norethindrone produced ...
... minutes and this led an impetus to search for an appropriate formulation that can give better dissolution profile. Mechanical methods of micronization are simple, efficient and cost effective way of achieving particle size reduction. The formulation developed using micronized Norethindrone produced ...
- Wiley Online Library
... responses to NSAIDs, namely their anti-inflammatory, antipyretic and analgesic effects. The model should also be developed in a medium-sized species (e.g. dog, cat) to enable both collection of clinically relevant endpoints and sequential blood sampling for determination of drug concentration in blo ...
... responses to NSAIDs, namely their anti-inflammatory, antipyretic and analgesic effects. The model should also be developed in a medium-sized species (e.g. dog, cat) to enable both collection of clinically relevant endpoints and sequential blood sampling for determination of drug concentration in blo ...
A Position Paper - American College of Physicians
... Position 1b: Medical marijuana research should not only focus on determining drug efficacy and safety but also on determining efficacy in comparison with other available treatments. Most of the conditions for which efficacy of cannabinoid drugs has been determined already have well-established and e ...
... Position 1b: Medical marijuana research should not only focus on determining drug efficacy and safety but also on determining efficacy in comparison with other available treatments. Most of the conditions for which efficacy of cannabinoid drugs has been determined already have well-established and e ...
Medicated Chewing Gum- A Mobile Oral Drug Delivery System
... allergy, nausea, motion sickness, diabetes, anxiety, dyspepsia, osteoporosis, cough, common cold etc. Medicated chewing gums are used not only for special population groups with swallowing difficulties such as children and the elderly, but also popular amongst the young generation. Thus chewing gum ...
... allergy, nausea, motion sickness, diabetes, anxiety, dyspepsia, osteoporosis, cough, common cold etc. Medicated chewing gums are used not only for special population groups with swallowing difficulties such as children and the elderly, but also popular amongst the young generation. Thus chewing gum ...
Acetylsalicylic acid - Wiley Online Library
... The usual oral dose of ASA as an analgesic and antipyretic is 300–1000 mg as a single dose, repeated every 4–8 h according to clinical needs.6 The maximum daily dose is 3–4 g. Acetylsalicylic acid is also used for its antiplatelet activity in the initial treatment of cardiovascular disorders such as ...
... The usual oral dose of ASA as an analgesic and antipyretic is 300–1000 mg as a single dose, repeated every 4–8 h according to clinical needs.6 The maximum daily dose is 3–4 g. Acetylsalicylic acid is also used for its antiplatelet activity in the initial treatment of cardiovascular disorders such as ...
Adverse_Events_White_Paper
... risk, or the total time exposed. We concur with sources that include “person-time” or “exposureadjusted” in the name when time is used in the denominator for clarity. Adverse event (AE): Any untoward medical occurrence associated with the use of a study drug in humans, whether or not it is considere ...
... risk, or the total time exposed. We concur with sources that include “person-time” or “exposureadjusted” in the name when time is used in the denominator for clarity. Adverse event (AE): Any untoward medical occurrence associated with the use of a study drug in humans, whether or not it is considere ...
GPAT 2010 Question Paper
... Q.17 Myasthenia gravis is diagnosed with improved neuromuscular function by using (A) Donepezil (B) Edrophonium (C) Atropine (D) Pancuronium Ans. Q.18 Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes? (A) Daclizumab (B) Prednisone (C) Sirolimus (D) Ta ...
... Q.17 Myasthenia gravis is diagnosed with improved neuromuscular function by using (A) Donepezil (B) Edrophonium (C) Atropine (D) Pancuronium Ans. Q.18 Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes? (A) Daclizumab (B) Prednisone (C) Sirolimus (D) Ta ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.