STUDIES ON THE PHYSICO-PHYTOCHEMICAL PROPERTIES AND HEPATOPROTECTIVE EFFECT SOLANUM TORVUM
... serum bilirubin levels which is indicative of liver toxicity. It is to be noted here that although both SGOT and SGPT levels get elevated during liver damage. GOT is a liver specific enzyme32 whose elevation suggests liver damage. Lactate dehydrogenate (LDH) activity may be elevated in all cases of ...
... serum bilirubin levels which is indicative of liver toxicity. It is to be noted here that although both SGOT and SGPT levels get elevated during liver damage. GOT is a liver specific enzyme32 whose elevation suggests liver damage. Lactate dehydrogenate (LDH) activity may be elevated in all cases of ...
Hidden Dangers: Herbal and Dietary Supplement Induced
... (HDS) are not classified as drugs and by definition, are not intended to prevent, diagnose, treat, mitigate, or cure diseases.5 Citing lack of questioning to fear of disapproval from their primary care physicians, over 40% do not disclose use of CAM, including a quarter of those taking supplements.6 ...
... (HDS) are not classified as drugs and by definition, are not intended to prevent, diagnose, treat, mitigate, or cure diseases.5 Citing lack of questioning to fear of disapproval from their primary care physicians, over 40% do not disclose use of CAM, including a quarter of those taking supplements.6 ...
Drug Calculations for Nurses A Step by Step Approach
... In the past, the British Approved Name (BAN) was used for drugs in the UK. European law now requires use of the Recommended International Non-proprietary Name (rINN) for medicinal substances. In most cases, the old BAN and the new rINN are identical. Where the two differ, the BAN has been modified t ...
... In the past, the British Approved Name (BAN) was used for drugs in the UK. European law now requires use of the Recommended International Non-proprietary Name (rINN) for medicinal substances. In most cases, the old BAN and the new rINN are identical. Where the two differ, the BAN has been modified t ...
04_Intravenous infusion
... concentration of a drug with one compartment PK resulting from the administration of an IV infusion (K0= Css∙Cl ) and a loading bolus (LD= Css∙Vd) that was given at the start of the infusion ...
... concentration of a drug with one compartment PK resulting from the administration of an IV infusion (K0= Css∙Cl ) and a loading bolus (LD= Css∙Vd) that was given at the start of the infusion ...
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR SIMULTANEOUS
... antiretroviral drugs that act by competing with natural deoxynucleotides to be incorporated into the viral DNA chain [1]. There are several such drugs available in the market for treatment of HIV including Tenofovir disoproxil fumarate (TDF) and Lamivudine (LMV). Lamivudine (LMV) has been mentioned ...
... antiretroviral drugs that act by competing with natural deoxynucleotides to be incorporated into the viral DNA chain [1]. There are several such drugs available in the market for treatment of HIV including Tenofovir disoproxil fumarate (TDF) and Lamivudine (LMV). Lamivudine (LMV) has been mentioned ...
Eszopiclone
... The primary endpoint was the average sleep latency over the last three months of the first six months of the study. The secondary endpoint was total sleep time over the same time period. These data were not presented ordiscussed. The authors stated that seven other time points (weekone, and monthly ...
... The primary endpoint was the average sleep latency over the last three months of the first six months of the study. The secondary endpoint was total sleep time over the same time period. These data were not presented ordiscussed. The authors stated that seven other time points (weekone, and monthly ...
10117sgp02
... The primary endpoint was the average sleep latency over the last three months of the first six months of the study. The secondary endpoint was total sleep time over the same time period. These data were not presented ordiscussed. The authors stated that seven other time points (weekone, and monthly ...
... The primary endpoint was the average sleep latency over the last three months of the first six months of the study. The secondary endpoint was total sleep time over the same time period. These data were not presented ordiscussed. The authors stated that seven other time points (weekone, and monthly ...
SPORANOX® Oral Solution
... Oral Candidiasis: Two randomised, double-blind studies using fluconazole as a comparator were conducted in Group IV HIV-positive adults with culture proven oral candidiasis. In one study, itraconazole 100 mg b.i.d. (n = 135) was compared to fluconazole 100 mg o.d. (n = 132) each given for 7 days. M ...
... Oral Candidiasis: Two randomised, double-blind studies using fluconazole as a comparator were conducted in Group IV HIV-positive adults with culture proven oral candidiasis. In one study, itraconazole 100 mg b.i.d. (n = 135) was compared to fluconazole 100 mg o.d. (n = 132) each given for 7 days. M ...
KINETIC STUDY OF ACAMPROSATE ABSORPTION IN RAT SMALL
... mechanism has not been studied in depth. The present study was therefore planned to characterize the intestinal transport of acamprosate in the rat and the effect of chronic alcohol treatment on this process, quantifying its kinetic parameters and investigating possible inhibitors. Using an in vitro ...
... mechanism has not been studied in depth. The present study was therefore planned to characterize the intestinal transport of acamprosate in the rat and the effect of chronic alcohol treatment on this process, quantifying its kinetic parameters and investigating possible inhibitors. Using an in vitro ...
Medical Marijuana And Methadone Treatment Programs Jassin M
... activates a specific type of opioid receptor in the body, the M receptor, and makes it similar in effect to heroin or morphine. Methadone is a synthetic drug. It was first developed during the early 20th century by several physicians who were searching for an opioid analgesic to administer during i ...
... activates a specific type of opioid receptor in the body, the M receptor, and makes it similar in effect to heroin or morphine. Methadone is a synthetic drug. It was first developed during the early 20th century by several physicians who were searching for an opioid analgesic to administer during i ...
Application of Hepatocytes for In Vitro Uptake Studies
... Effect of hepatocyte concentration in incubation High hepatocyte concentrations in incubation decreases observed metabolic clearance for transported drugs Result: Unbound cell-to-medium ratio decreases for actively transported drugs with increasing hepatocyte concentration Lower [Drug] in hepatocyte ...
... Effect of hepatocyte concentration in incubation High hepatocyte concentrations in incubation decreases observed metabolic clearance for transported drugs Result: Unbound cell-to-medium ratio decreases for actively transported drugs with increasing hepatocyte concentration Lower [Drug] in hepatocyte ...
Guideline on medication error reporting.
... for inpatients in the year 2008 compared to 32 million and 6.9 million prescriptions respectively the previous year. This shows a significant increase in the number of prescriptions filled and dispensed by pharmacy and the growing trend is very likely to continue in the years ahead. The large amount ...
... for inpatients in the year 2008 compared to 32 million and 6.9 million prescriptions respectively the previous year. This shows a significant increase in the number of prescriptions filled and dispensed by pharmacy and the growing trend is very likely to continue in the years ahead. The large amount ...
Hair Analysis for Cocaine: The Requirement for Effective Wash
... there are further considerations of the role of washing in quantitative analysis of hair for meaningful interpretation. Contamination by drugs from sweat on the surface of the skin is an acknowledged route for deposition of drugs on hair (1,2). Because a nonuser's sweat would not contain drug, sweat ...
... there are further considerations of the role of washing in quantitative analysis of hair for meaningful interpretation. Contamination by drugs from sweat on the surface of the skin is an acknowledged route for deposition of drugs on hair (1,2). Because a nonuser's sweat would not contain drug, sweat ...
Guideline on the investigation of bioequivalence - EMA
... esters, ethers, isomers, mixtures of isomers, complexes or derivatives of an active substance are considered to be the same active substance, unless they differ significantly in properties with regard to safety and/or efficacy. Furthermore, the various immediate-release oral pharmaceutical forms sha ...
... esters, ethers, isomers, mixtures of isomers, complexes or derivatives of an active substance are considered to be the same active substance, unless they differ significantly in properties with regard to safety and/or efficacy. Furthermore, the various immediate-release oral pharmaceutical forms sha ...
Impurities: Guideline for Residual Solvents
... recommended level, the drug product should be tested to ascertain whether the formulation process has reduced the relevant solvent level to within the acceptable amount. Drug product should also be tested if a solvent is used during its manufacture. This guideline does not apply to potential new dru ...
... recommended level, the drug product should be tested to ascertain whether the formulation process has reduced the relevant solvent level to within the acceptable amount. Drug product should also be tested if a solvent is used during its manufacture. This guideline does not apply to potential new dru ...
Evaluation of Naltrexone as a Treatment for Amphetamine
... obtain, pharmacological companies sought to identify synthetic substitutes. In 1887, amphetamine proper was first synthesized as part of a programme to manufacture aliphatic amines. As early as 1919, a Japanese chemist synthesized methylamphetamine (commonly referred to as methamphetamine, and a mor ...
... obtain, pharmacological companies sought to identify synthetic substitutes. In 1887, amphetamine proper was first synthesized as part of a programme to manufacture aliphatic amines. As early as 1919, a Japanese chemist synthesized methylamphetamine (commonly referred to as methamphetamine, and a mor ...
![[Salvia divinorum - a potential drug for abuse]](http://s1.studyres.com/store/data/007845527_1-baa04152dad6511298825048970e3c2d-300x300.png)
[Salvia divinorum - a potential drug for abuse]
... Selective kappa receptoragonists have been shown to produce analgesic effects with potential for reduced tolerance and dependence. However, psychotomimesis (hallucinogenic and/or psychotic effects), dysphoria and diuresis have been observed with their therapeutic use (Tidgewell et aI., 2004). In add ...
... Selective kappa receptoragonists have been shown to produce analgesic effects with potential for reduced tolerance and dependence. However, psychotomimesis (hallucinogenic and/or psychotic effects), dysphoria and diuresis have been observed with their therapeutic use (Tidgewell et aI., 2004). In add ...
and 7-hydroxymethotrexate
... effect of MTX when administered concomitantly with other drugs cannot be explained solely by protein-binding displacement and the possible mechanism in case of PIP may be accumulation of 7-OH-MTX in the body. Our results suggest that the decrease in renal tubular secretion of MTX may not be the only ...
... effect of MTX when administered concomitantly with other drugs cannot be explained solely by protein-binding displacement and the possible mechanism in case of PIP may be accumulation of 7-OH-MTX in the body. Our results suggest that the decrease in renal tubular secretion of MTX may not be the only ...
Effects of Antipsychotic Drugs on Extracellular Dopamine Levels in
... Accepted for publication September 14, 1998 ...
... Accepted for publication September 14, 1998 ...
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED
... quetiapine while taking trazodone and fluoxetine treatment. In this paper we take a look at the literature concerning quetiapine and dystonia. In this context it is warranted to be aware of combination therapy’s side effects, including ones that are considered having a lower risk of extrapyramidal s ...
... quetiapine while taking trazodone and fluoxetine treatment. In this paper we take a look at the literature concerning quetiapine and dystonia. In this context it is warranted to be aware of combination therapy’s side effects, including ones that are considered having a lower risk of extrapyramidal s ...
PRODUCT MONOGRAPH Pr INDERAL®-LA (Propranolol
... INDERAL-LA acts selectively without completely abolishing the inotropic action of digitalis on the heart muscle (i.e. that of supporting the strength of myocardial contractions). In patients already receiving digitalis, the positive inotropic action of digitalis may be reduced by propranolol hydroch ...
... INDERAL-LA acts selectively without completely abolishing the inotropic action of digitalis on the heart muscle (i.e. that of supporting the strength of myocardial contractions). In patients already receiving digitalis, the positive inotropic action of digitalis may be reduced by propranolol hydroch ...
Lethal Injection for Execution: Chemical Asphyxiation?
... laboratory settings, local oversight bodies known as Animal Care and Use Committees typically follow the American Veterinary Medical Association’s guidelines on euthanasia, which consider all aspects of euthanasia methods, including drugs, tools, and expertise of personnel in order to minimize pain ...
... laboratory settings, local oversight bodies known as Animal Care and Use Committees typically follow the American Veterinary Medical Association’s guidelines on euthanasia, which consider all aspects of euthanasia methods, including drugs, tools, and expertise of personnel in order to minimize pain ...
Major Stimulants - People Server at UNCW
... "Vanilla Sky," "White Lightning," "Scarface," and "Hurricane Charlie." Because these products are relatively new to the drug abuse scene, our knowledge about their precise chemical composition and short- and long-term effects is limited, yet the information we do have is worrisome and warrants a pro ...
... "Vanilla Sky," "White Lightning," "Scarface," and "Hurricane Charlie." Because these products are relatively new to the drug abuse scene, our knowledge about their precise chemical composition and short- and long-term effects is limited, yet the information we do have is worrisome and warrants a pro ...
Department for Transport - Over-the
... limit for driving in this country. Each class of drug was reviewed individually. We looked at its structure and function, pharmacokinetics, sedating properties and its effect on performance. Although some of the drugs reviewed do not usually cause sedation at the recommended dose, if taken above the ...
... limit for driving in this country. Each class of drug was reviewed individually. We looked at its structure and function, pharmacokinetics, sedating properties and its effect on performance. Although some of the drugs reviewed do not usually cause sedation at the recommended dose, if taken above the ...
An overview of interactions between grapefruit juice and drugs ReView Abstract
... activity in the intestine will tend to have a relatively high area under the curve (AUC). On the other hand, subjects with high intestinal CYP3A4 activity will exhibit a marked increase in AUC when affected drugs are taken with grapefruit juice. Another situation might arise in a patient with severe ...
... activity in the intestine will tend to have a relatively high area under the curve (AUC). On the other hand, subjects with high intestinal CYP3A4 activity will exhibit a marked increase in AUC when affected drugs are taken with grapefruit juice. Another situation might arise in a patient with severe ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.