AusPAR: Sevelamer hydrochloride
... comparison of the total titratable amines and phosphate binding capacity of the drug substance used in the proposed and innovator products was provided. If any conclusion can be drawn from this information it may be that the proposed drug substance has marginally fewer free amine sites as compared w ...
... comparison of the total titratable amines and phosphate binding capacity of the drug substance used in the proposed and innovator products was provided. If any conclusion can be drawn from this information it may be that the proposed drug substance has marginally fewer free amine sites as compared w ...
Ranzith®
... taken in patients with severe renal impairment. Overdosage There is no data on over dosage with Azithromycin. Typical symptoms of over dosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhea. Gastric lavage and general supportive measures are indicated. Drug Inte ...
... taken in patients with severe renal impairment. Overdosage There is no data on over dosage with Azithromycin. Typical symptoms of over dosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhea. Gastric lavage and general supportive measures are indicated. Drug Inte ...
Drug-induced oral lichenoid reactions. A literature review
... The term “histologically compatible with” is to be used in application to all histopathological findings less clearly compliant with the mentioned criteria. Final diagnosis of oral lichen planus and oral lichenoid lesions: The clinical and histopathological criteria must be included in order to esta ...
... The term “histologically compatible with” is to be used in application to all histopathological findings less clearly compliant with the mentioned criteria. Final diagnosis of oral lichen planus and oral lichenoid lesions: The clinical and histopathological criteria must be included in order to esta ...
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... worldwide [1]. The emergence of drug-resistant strains of Mycobacterium tuberculosis is substantially challenging the goal of elimination of TB in the 21st century. The estimated global number of multidrugresistant (MDR) and extensively drug-resistant (XDR)-TB cases among newly diagnosed patients wi ...
... worldwide [1]. The emergence of drug-resistant strains of Mycobacterium tuberculosis is substantially challenging the goal of elimination of TB in the 21st century. The estimated global number of multidrugresistant (MDR) and extensively drug-resistant (XDR)-TB cases among newly diagnosed patients wi ...
Studies on Variability in Olanzapine Disposition
... Schizophrenia and schizoaffective disorders are chronic conditions with a significant impact on many functions. Positive, negative, cognitive and motor symptoms appear in different degrees and constellations. Antipsychotics are of fundamental importance to reduce symptoms. However, insufficient clin ...
... Schizophrenia and schizoaffective disorders are chronic conditions with a significant impact on many functions. Positive, negative, cognitive and motor symptoms appear in different degrees and constellations. Antipsychotics are of fundamental importance to reduce symptoms. However, insufficient clin ...
GLOBAL SMART UPDATE - Descentraliza Drogas
... cannabis but rather synthetic cannabinoids which produce cannabis-like effects. Labelled ‘not for human consumption’, these products typically contain dried shredded plant material – which by itself, has no psychoactive properties – that is soaked in or sprayed with one or several synthetic cannabin ...
... cannabis but rather synthetic cannabinoids which produce cannabis-like effects. Labelled ‘not for human consumption’, these products typically contain dried shredded plant material – which by itself, has no psychoactive properties – that is soaked in or sprayed with one or several synthetic cannabin ...
Pharmacology
... Renal / DM / HTN / (and probably any form of) proteinuria renoprotective by at least 2 mechanisms reduction of glomerular pressure (by relaxing efferent constriction) blocking action and local formation of TGF-B1 (which causes mesangial proliferation) Other: ACE inhibitors are protective against ...
... Renal / DM / HTN / (and probably any form of) proteinuria renoprotective by at least 2 mechanisms reduction of glomerular pressure (by relaxing efferent constriction) blocking action and local formation of TGF-B1 (which causes mesangial proliferation) Other: ACE inhibitors are protective against ...
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... worldwide [1]. The emergence of drug-resistant strains of Mycobacterium tuberculosis is substantially challenging the goal of elimination of TB in the 21st century. The estimated global number of multidrugresistant (MDR) and extensively drug-resistant (XDR)-TB cases among newly diagnosed patients wi ...
... worldwide [1]. The emergence of drug-resistant strains of Mycobacterium tuberculosis is substantially challenging the goal of elimination of TB in the 21st century. The estimated global number of multidrugresistant (MDR) and extensively drug-resistant (XDR)-TB cases among newly diagnosed patients wi ...
- International Journal of Pharmaceutical Sciences and
... In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. The reasons that the oral route achieved such popularity may be in part attributed to its ease of administration. Over the years, patient convenience and patient com ...
... In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. The reasons that the oral route achieved such popularity may be in part attributed to its ease of administration. Over the years, patient convenience and patient com ...
STUDY OF THE ROLE OF THE BED NUCLEUS OF
... The use of drug self-administration in animal models has helped understanding of certain elements of the process to drug addiction. Animal models of drug selfadministration have construct and predictive validity when it comes to its concordance with the human form of addiction. Construct validity re ...
... The use of drug self-administration in animal models has helped understanding of certain elements of the process to drug addiction. Animal models of drug selfadministration have construct and predictive validity when it comes to its concordance with the human form of addiction. Construct validity re ...
Drug and Reinforcement History as Determinants of the Response
... Gregory T. Collins and James H. Woods Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan Received March 19, 2007; accepted August 2, 2007 ...
... Gregory T. Collins and James H. Woods Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan Received March 19, 2007; accepted August 2, 2007 ...
Clinical Guidance for the use of medicinal cannabis products in
... recreationally, which are much more harmful, for example—HU-210 and JWH-018. Synthetic cannabinoids are not only full agonists at both CB1 and CB2 receptors, but they have 50 to 200 times increased affinity for the CB1 receptor compared with naturally occurring cannabinoids. ...
... recreationally, which are much more harmful, for example—HU-210 and JWH-018. Synthetic cannabinoids are not only full agonists at both CB1 and CB2 receptors, but they have 50 to 200 times increased affinity for the CB1 receptor compared with naturally occurring cannabinoids. ...
Antipsychotic Use in the Elderly
... of alternative drug classes (e.g., benzodiazepines, typical antipsychotics) was not modeled and should be carefully considered when implementing any policy changes or designing programs aimed at reducing inappropriate prescribing of any one drug class. Note that these recommendations are NOT applica ...
... of alternative drug classes (e.g., benzodiazepines, typical antipsychotics) was not modeled and should be carefully considered when implementing any policy changes or designing programs aimed at reducing inappropriate prescribing of any one drug class. Note that these recommendations are NOT applica ...
FDA Approved Labeling 12.19.08 3pm NovaDel Pharma Inc.
... Use in patients with depression: As with other sedative-hypnotic drugs, Zolpimist should be administered with caution to patients exhibiting signs or symptoms of depression. Suicidal tendencies may be present in such patients and protective measures may be required. Intentional over-dosage is more c ...
... Use in patients with depression: As with other sedative-hypnotic drugs, Zolpimist should be administered with caution to patients exhibiting signs or symptoms of depression. Suicidal tendencies may be present in such patients and protective measures may be required. Intentional over-dosage is more c ...
Why Marijuana Legalization is NOT a Good Idea For Texas
... The truth is that the use of marijuana is significantly affecting the quality-oflife of Texans – to the extent that it is the drug for which more individuals are seeking treatment services at state-funded facilities than for any other drug type except alcohol.1 The level of tetrahydrocannabinol (THC ...
... The truth is that the use of marijuana is significantly affecting the quality-oflife of Texans – to the extent that it is the drug for which more individuals are seeking treatment services at state-funded facilities than for any other drug type except alcohol.1 The level of tetrahydrocannabinol (THC ...
here - Patent Docs
... the CONCERTA drug product is an act of infringement of one or more claims of the '798 Patent entitling Plaintiffs to the relief provided by 35 U.S.C. § 271(e)(4), including, inter alia, an order of this Court that the effective date of approval for ANDA No. 206726 be a date which is not earlier than ...
... the CONCERTA drug product is an act of infringement of one or more claims of the '798 Patent entitling Plaintiffs to the relief provided by 35 U.S.C. § 271(e)(4), including, inter alia, an order of this Court that the effective date of approval for ANDA No. 206726 be a date which is not earlier than ...
Micromedex User guide
... This manual, as well as the data and software implementation described in it, is furnished under license and may be used or copied only in accordance with the terms of such license. The content of this manual is furnished for informational use only, is subject to change without notice, and should no ...
... This manual, as well as the data and software implementation described in it, is furnished under license and may be used or copied only in accordance with the terms of such license. The content of this manual is furnished for informational use only, is subject to change without notice, and should no ...
user guide - Micromedex
... This manual, as well as the data and software implementation described in it, is furnished under license and may be used or copied only in accordance with the terms of such license. The content of this manual is furnished for informational use only, is subject to change without notice, and should no ...
... This manual, as well as the data and software implementation described in it, is furnished under license and may be used or copied only in accordance with the terms of such license. The content of this manual is furnished for informational use only, is subject to change without notice, and should no ...
Advances in Lung Cancer 2016: a year in review
... rovalpituzumab tesirine (Rova-T) – likely by 2017/2018 Immune checkpoint inhibitors (anti-PD-1 agents) nivolumab (off-label use since 2015) pembrolizumab (off-label use since 2015) - likely FDA approval of anti-PD-1 by 2017/2018 ...
... rovalpituzumab tesirine (Rova-T) – likely by 2017/2018 Immune checkpoint inhibitors (anti-PD-1 agents) nivolumab (off-label use since 2015) pembrolizumab (off-label use since 2015) - likely FDA approval of anti-PD-1 by 2017/2018 ...
Prescribing Information
... Africans, Ethiopians, and Arabs. Data are not available for other ethnic groups. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in higher than ...
... Africans, Ethiopians, and Arabs. Data are not available for other ethnic groups. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in higher than ...
Uptake of Methotrexate, Aminopterin, and
... probably due primarily to specific action of the agents on the drugs were essentially the same; the single end point depicted conversion of deoxyuridylic to thymidylic acid. This assumption is supported by an experiment in which large doses of aminopterin and MQ were shown to have relatively little ...
... probably due primarily to specific action of the agents on the drugs were essentially the same; the single end point depicted conversion of deoxyuridylic to thymidylic acid. This assumption is supported by an experiment in which large doses of aminopterin and MQ were shown to have relatively little ...
WARNING: DEATH RELATED TO ULTRA
... in Caucasians, 3% in African Americans, and 16 to 28% in North Africans, Ethiopians, and Arabs. Data are not available for other ethnic groups. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in high ...
... in Caucasians, 3% in African Americans, and 16 to 28% in North Africans, Ethiopians, and Arabs. Data are not available for other ethnic groups. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in high ...
Evaluation of the Anti Platelet Aggregation Effects of Diltiazem
... Intra platelet concentration is increased through PLC and IP3 mediated release of Ca++ from endoplasmic reticulum, ROC (receptor operated channels) and TRPC (transient receptor potential channels) that mediate Ca++ entry through the plasma membrane [7]. Paul Erne [8] proved that intra sytosolic Ca++ ...
... Intra platelet concentration is increased through PLC and IP3 mediated release of Ca++ from endoplasmic reticulum, ROC (receptor operated channels) and TRPC (transient receptor potential channels) that mediate Ca++ entry through the plasma membrane [7]. Paul Erne [8] proved that intra sytosolic Ca++ ...
Routine analysis of amphetamine class drugs as their
... Primary and secondary amino groups of amphetamines react with NQS in alkaline solution to form highly coloured compounds (Fig. 1) which can be determined colourimetrically [24]. Absorbance maxima occur in the visible region (450 nm) and in the UV region (260 nm). Derivatisation of amphetamine and me ...
... Primary and secondary amino groups of amphetamines react with NQS in alkaline solution to form highly coloured compounds (Fig. 1) which can be determined colourimetrically [24]. Absorbance maxima occur in the visible region (450 nm) and in the UV region (260 nm). Derivatisation of amphetamine and me ...
M P D U
... person being treated for lung cancer could be administered approximately 1,000 mg of Avastin every 3 weeks. ...
... person being treated for lung cancer could be administered approximately 1,000 mg of Avastin every 3 weeks. ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.