03_Intravenous infusion and Laplace
... concentration of a drug with one compartment PK resulting from the administration of an IV infusion (K0= Css∙Cl ) and a loading bolus (LD= Css∙Vd) that was given at the start of the infusion ...
... concentration of a drug with one compartment PK resulting from the administration of an IV infusion (K0= Css∙Cl ) and a loading bolus (LD= Css∙Vd) that was given at the start of the infusion ...
S02 Techno2 Hard Gelatin Capsules
... However, lubricants are not always disadvantageous. They were shown to increase the dissolution rate of micronized powders. This is due to reduction in cohesiveness of the small particles, thus spreading more rapidly through the dissolution medium than the unlubricated particles. Studies have sh ...
... However, lubricants are not always disadvantageous. They were shown to increase the dissolution rate of micronized powders. This is due to reduction in cohesiveness of the small particles, thus spreading more rapidly through the dissolution medium than the unlubricated particles. Studies have sh ...
Full text in pdf format
... Survival and impact on molt success Survival differed among the groups (χ2 = 19.9, df = 4, p < 0.001). Survival in the 4- and 8-dose groups (45%) was significantly lower than in the control (100%) and 1- and 2-dose groups (76 and 75%, respectively, Marascuillo procedure; Fig. 1B). Control lobsters h ...
... Survival and impact on molt success Survival differed among the groups (χ2 = 19.9, df = 4, p < 0.001). Survival in the 4- and 8-dose groups (45%) was significantly lower than in the control (100%) and 1- and 2-dose groups (76 and 75%, respectively, Marascuillo procedure; Fig. 1B). Control lobsters h ...
“Synthesis, characterization and biomedical applications of microbial polymalic and polyglutamic acids derivatives.”
... The reaction mixture was then evaporated under vacuum and the residue was dissolved in a small amount of N-methyl pyrrolidone (NMP) and added with cold diethyl ether, the PMLA methyl esters being recovered by filtration as white powders. coPMLA-(MexHy) with nominally methylation degrees of 25, 50 a ...
... The reaction mixture was then evaporated under vacuum and the residue was dissolved in a small amount of N-methyl pyrrolidone (NMP) and added with cold diethyl ether, the PMLA methyl esters being recovered by filtration as white powders. coPMLA-(MexHy) with nominally methylation degrees of 25, 50 a ...
Preview the material
... study of the chemical separation of particular active agents from their complicated and complex mixtures, often plant extracts. It began with scientists predicting the impacts of medicine on the human patient. This led to further investigations of the effects of specific agents on isolated organs. O ...
... study of the chemical separation of particular active agents from their complicated and complex mixtures, often plant extracts. It began with scientists predicting the impacts of medicine on the human patient. This led to further investigations of the effects of specific agents on isolated organs. O ...
Metoprolol iv to oral equivalent
... succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Learn about Toprol XL (Metoprolol Succinate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ...
... succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Learn about Toprol XL (Metoprolol Succinate) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related ...
zidovudine and lamivudine - WHO archives
... children had received treatment. A prospective observational cohort study was undertaken to assess the feasibility, effectiveness, adherence, toxicity and viral resistance of antiretroviral therapy. The clinical and biological results of the study were comparable to those seen in western cohorts, de ...
... children had received treatment. A prospective observational cohort study was undertaken to assess the feasibility, effectiveness, adherence, toxicity and viral resistance of antiretroviral therapy. The clinical and biological results of the study were comparable to those seen in western cohorts, de ...
LSEHWP39
... treated WWE were treated on monotherapy, whereas the remaining 23.6.% on polytherapy. Among monotherapy regimes the most frequently used AEDs were valproate, carbamazepine, lamotrigine, phenytoine, phenobarbital and oxcarbazepine. Average rates of adverse pregnancy outcomes (obstetric, delivery and ...
... treated WWE were treated on monotherapy, whereas the remaining 23.6.% on polytherapy. Among monotherapy regimes the most frequently used AEDs were valproate, carbamazepine, lamotrigine, phenytoine, phenobarbital and oxcarbazepine. Average rates of adverse pregnancy outcomes (obstetric, delivery and ...
Chemotherapy extravasation guideline
... These injuries range from less significant erythematous reactions to skin sloughing and necrosis. Whilst extravasation is possible with any intravenous injection it is only considered to be problematic with compounds known to have irritant or vesicant properties. The onset of symptoms may occur imme ...
... These injuries range from less significant erythematous reactions to skin sloughing and necrosis. Whilst extravasation is possible with any intravenous injection it is only considered to be problematic with compounds known to have irritant or vesicant properties. The onset of symptoms may occur imme ...
Development of a facile antibody–drug conjugate
... maleimides by accelerating the thiosuccinimide ring hydrolysis have been shown to result in more efficacious and relatively safer ADCs.12 Alternative strategies to maleimide-based conjugations have also surfaced where the disuldes are re-bridged aer cysteine reduction.4 Despite the potential advanta ...
... maleimides by accelerating the thiosuccinimide ring hydrolysis have been shown to result in more efficacious and relatively safer ADCs.12 Alternative strategies to maleimide-based conjugations have also surfaced where the disuldes are re-bridged aer cysteine reduction.4 Despite the potential advanta ...
BCLT-R2ppt DRAFT 3
... halogenated hydrocarbons or digitalis glycosides may cause cardiac arrhythmias, since these medications may sensitize the myocardium to the effects of ephedrine sulfate. Therapeutic doses of ephedrine sulfate can inhibit the hypotensive effect of guanethidine, bethanidine, and debrisoquin by displac ...
... halogenated hydrocarbons or digitalis glycosides may cause cardiac arrhythmias, since these medications may sensitize the myocardium to the effects of ephedrine sulfate. Therapeutic doses of ephedrine sulfate can inhibit the hypotensive effect of guanethidine, bethanidine, and debrisoquin by displac ...
NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS)
... flow to the gastric muscosal cells. Since NSAIDs block PG biosynthesis in the GI tract, they block these cytoprotective processes. The primary toxicity seen with the NSAIDs is GI irritation which may lead to the production of ulcers when used in large doses over a long period of time. This occurs qu ...
... flow to the gastric muscosal cells. Since NSAIDs block PG biosynthesis in the GI tract, they block these cytoprotective processes. The primary toxicity seen with the NSAIDs is GI irritation which may lead to the production of ulcers when used in large doses over a long period of time. This occurs qu ...
Pain Management - Pain Medications and Over-The
... treat inflammation, mild to moderate pain, and fever. Specific uses include the treatment of headaches, arthritis, sports injuries, and menstrual cramps. Aspirin (also an NSAID) is used to inhibit the clotting of blood and prevent strokes and heart attacks in individuals at high risk. NSAIDs also ar ...
... treat inflammation, mild to moderate pain, and fever. Specific uses include the treatment of headaches, arthritis, sports injuries, and menstrual cramps. Aspirin (also an NSAID) is used to inhibit the clotting of blood and prevent strokes and heart attacks in individuals at high risk. NSAIDs also ar ...
Marine Origin Polysaccharides in Drug Delivery Systems
... and purification processes [1,2]. Marine biomaterials have wide applicability in biomedicine because of their noncytotoxic characteristics, biodegradability and biocompatibility. These biological properties have allowed the discovery of a broad range of novel bioactive compounds with pharmacological ...
... and purification processes [1,2]. Marine biomaterials have wide applicability in biomedicine because of their noncytotoxic characteristics, biodegradability and biocompatibility. These biological properties have allowed the discovery of a broad range of novel bioactive compounds with pharmacological ...
Keppra® (levetiracetam)
... An FDA meta-analysis of randomized placebo controlled trials, in which antiepileptic drugs were used for various indications, has shown a small increased risk of suicidal ideation and behavior in patients treated with these drugs. The mechanism of this risk is not known. There were 43892 patients in ...
... An FDA meta-analysis of randomized placebo controlled trials, in which antiepileptic drugs were used for various indications, has shown a small increased risk of suicidal ideation and behavior in patients treated with these drugs. The mechanism of this risk is not known. There were 43892 patients in ...
CHITOSAN LOADED MICROSPHERES AS AN OCULAR DELIVERY SYSTEM FOR ACYCLOVIR S.SELVARAJ
... cationic polymer chitosan has attracted a great deal of attention because of its unique properties, such as acceptable biocompatibility 28, biodegradability and ability to enhance the paracelluar transport of drugs29. Besides, the cornea and conjunctiva have a negative charge; use of the cationic po ...
... cationic polymer chitosan has attracted a great deal of attention because of its unique properties, such as acceptable biocompatibility 28, biodegradability and ability to enhance the paracelluar transport of drugs29. Besides, the cornea and conjunctiva have a negative charge; use of the cationic po ...
the full case study
... takes on a regular basis. His doctor referred him to me to evaluate the need for all of these drugs. It was inspiring to talk to him and marvel over his very sharp and clear cognitive abilities as well as his physical condition. He has a sister who is 91 and another that is 97 who live close by and ...
... takes on a regular basis. His doctor referred him to me to evaluate the need for all of these drugs. It was inspiring to talk to him and marvel over his very sharp and clear cognitive abilities as well as his physical condition. He has a sister who is 91 and another that is 97 who live close by and ...
article
... herbal products in Palestine. In our study, the majority of pharmacists reported receiving inquires about herbal medicine by the general public. Herbal products are commonly used and dispensed in the neighboring countries as well [17-20] . Almost all pharmacists in the United Arab Emirates (UAE) and ...
... herbal products in Palestine. In our study, the majority of pharmacists reported receiving inquires about herbal medicine by the general public. Herbal products are commonly used and dispensed in the neighboring countries as well [17-20] . Almost all pharmacists in the United Arab Emirates (UAE) and ...
Insomnia is not just a night-time problem
... reported that the majority of sleep medication is used over long periods of time, usually on a nightly basis for several years.18 The problem here is that clinical trials demonstrating efficacy of hypnotic medications were conducted over short periods (not more than six months) thus long-term value ...
... reported that the majority of sleep medication is used over long periods of time, usually on a nightly basis for several years.18 The problem here is that clinical trials demonstrating efficacy of hypnotic medications were conducted over short periods (not more than six months) thus long-term value ...
Antiplatelet Drugs - OSU Center for Continuing Medical Education
... acetylating the serine residue at position 529.42 Such an interaction could occur in the perioperative period when these drugs are often coadministered. Retrospective cohort studies have not demonstrated any increased risk of myocardial infarction (MI) when ketorolac was administered postoperatively ...
... acetylating the serine residue at position 529.42 Such an interaction could occur in the perioperative period when these drugs are often coadministered. Retrospective cohort studies have not demonstrated any increased risk of myocardial infarction (MI) when ketorolac was administered postoperatively ...
EŠects of Sho-saiko-to (Xiao Chai Hu Tang), a Chinese - J
... A prototype of sulphonylurea hypoglycemic agents, tolbutamide, has been widely used in pharmacotherpy for diabetes mellitus. This drug can be absorbed appreciably from the stomach as well as the duodenum in rats,12) so that the gastric functions such as gastric emptying and gastric acid secretion po ...
... A prototype of sulphonylurea hypoglycemic agents, tolbutamide, has been widely used in pharmacotherpy for diabetes mellitus. This drug can be absorbed appreciably from the stomach as well as the duodenum in rats,12) so that the gastric functions such as gastric emptying and gastric acid secretion po ...
Ephedrine and Other Stimulants As Ergogenic Aids
... through crushing tablets for sublingual mucosal absorption, usually for recreational purposes, and this use could lead to detection during drug testing by regulatory agencies such as the NCAA. Amphetamine was synthesized in 1920 and used to reduce fatigue and increase alertness during World War II. ...
... through crushing tablets for sublingual mucosal absorption, usually for recreational purposes, and this use could lead to detection during drug testing by regulatory agencies such as the NCAA. Amphetamine was synthesized in 1920 and used to reduce fatigue and increase alertness during World War II. ...
A Practical Guide for Clinicians Who Treat Patients with Amiodarone
... not responsive to, or the patient is intolerant of, other antiarrhythmic agents that might be suitable for treatment. It is the consensus of this committee that amiodarone is the antiarrhythmic drug of choice, in combination with other appropriate therapies such as beta-blocking agents, in patients ...
... not responsive to, or the patient is intolerant of, other antiarrhythmic agents that might be suitable for treatment. It is the consensus of this committee that amiodarone is the antiarrhythmic drug of choice, in combination with other appropriate therapies such as beta-blocking agents, in patients ...
bevacizumab
... into the ciliary body, iris and anterior chamber angle”. • “Penetration into Iris appears to be faster than that into ciliary body and anterior chamber angle.” • “The highest concentration is seen in the anterior chamber from day 1 to 4 after an Intra-Vitreal injection and it regresses by day 14.” ...
... into the ciliary body, iris and anterior chamber angle”. • “Penetration into Iris appears to be faster than that into ciliary body and anterior chamber angle.” • “The highest concentration is seen in the anterior chamber from day 1 to 4 after an Intra-Vitreal injection and it regresses by day 14.” ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.