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Sudden Cardiac Death - Backgrounder
Sudden Cardiac Death - Backgrounder

... Sudden cardiac arrest (SCA) is a life-threating heart condition that can lead to death if not treated within minutes. SCA results from an irregular or abnormal heart rhythm, due to a problem with the electrical system of the heart. There are generally two types of abnormal rhythms: • Ventricular tac ...
Heart Study Aid 1) Pericardium Fibrous ______ Parietal layer
Heart Study Aid 1) Pericardium Fibrous ______ Parietal layer

... 6) The functional blood supply of the heart is the ______________________ 7) Conduction system of the heart SA node (pacemaker) ...
Cardiac Resynchronization Therapy (CRT)
Cardiac Resynchronization Therapy (CRT)

... goes to the left side of the heart. Although most people have a vein that can be used for this purpose, this is not true of everyone. Therefore, this extra wire is occasionally placed on the outside of the heart during a surgical procedure or at the time of another heart operation, such as valve sur ...
MPI Patient Preparation Webinar Test (10 questions) 70% pass to
MPI Patient Preparation Webinar Test (10 questions) 70% pass to

... 4. Which of the following is a contraindication for exercise stress testing? A. Acute Pulmonary embolus (PE) B. High-risk unstable angina C. Uncontrolled Hypertension D. All of the above 5. True of False A suboptimal heart rate response, achieving <85% Maximum Predicted Heart Rate (MPHR) may lead to ...
View Abstract
View Abstract

... Background: An effective strategy for monitoring cardiac safety during anthracycline chemotherapy is not established. Serial left ventricular ejection fraction (LVEF) utilizing imaging is the current standard of care; however biomarkers may allow for earlier identification and treatment. Methods: A ...
Peripheral Vascular Disease
Peripheral Vascular Disease

... For patients who have left ventricular ejection fraction (LVEF) less than or equal to 35%, a QRS duration greater than or equal to 0.12 seconds, and sinus rhythm, cardiac resynchronization therapy (CRT) with or without an ICD is indicated for the treatment of New York Heart Association (NYHA) functi ...
Heart failure
Heart failure

... Correction of electrolytes and acid base imbalance In patients with ischemic cardiomyopathy → ICD implant is the option after r/o acute ischemia as the cause In patients wit non ischemic cardiomyopathy management is ICD implantation ...
Full Paper - Daniel Burkhoff MD PhD
Full Paper - Daniel Burkhoff MD PhD

... present analysis, we sought to identify if there was a subgroup of patients who showed a response to CCM. Methods and Results: The protocol specified that multiregression analysis would be used to determine if baseline EF, NYHA functional class, pVO2, or etiology of heart failure influenced the impa ...
S073510970802826X_mmc1
S073510970802826X_mmc1

... size of 26 patients, we achieved 80% power to detect a significant enhancement of cardiac index from +0.15 l/min in patients with intra-aortic balloon pump to +0.50 l/min in patients with Impella LP2.5 at an α level of 0.05. Hemodynamic parameters (arterial pressure, pulmonary arterial pressure, rig ...
Monitoring heart failure hemodynamics with an implanted
Monitoring heart failure hemodynamics with an implanted

... a manner comparable with, and perhaps complementary to, that provided by analysis of heart rate variability. Most patients undergoing cardiac catheterization to evaluate HF are studied in a postprandial state, supine, and lightly sedated, while they are not experiencing symptoms. A permanently impla ...
Heart Physiology
Heart Physiology

... •  Sinoatrial  (SA)  node  –  pacemaker  "sinus  rhythm".   •  Atrioventricular  (AV)  node   •  AV  Bundle   •  Bundle  branches   •  Purkinje  fibers   ...
summation and tetanus of cardiac muscle is impossible
summation and tetanus of cardiac muscle is impossible

... • Two specialized types of cardiac muscle cells – Contractile cells • 99% of cardiac muscle cells • Do mechanical work of pumping • Normally do not initiate own action potentials ...
cardiac muscle
cardiac muscle

... • Two specialized types of cardiac muscle cells – Contractile cells • 99% of cardiac muscle cells • Do mechanical work of pumping • Normally do not initiate own action potentials ...
Premature Ventricular Contractions (PVCs)
Premature Ventricular Contractions (PVCs)

... PVCs, or premature ventricular contractions, are “extra” heart beats that start in the lower portion of the heart. Nearly all of the 100,000 heart beats that occur each day start from the top part of the heart (the atria) that holds the “pacemaker” cells, which establish the heart rate. The normal p ...
C-1 Advanced Heart Failure
C-1 Advanced Heart Failure

... Primary PCI for STEMI in Nonagenarians This study reports that primary PCI can be safely and successfully performed in nonagenarians (> 90 years old) presenting with STEMI through a transradial approach. Similar to younger patients, this invasive strategy is associated with a high rate of achieved ...
Document
Document

... • Blanket term • Sometimes called Acute Coronary Syndrome or ACS • Refers to a cardiac event of rapid onset • ACS {ischemia} ...
Cardiac Resynchronization Therapy (CRT)
Cardiac Resynchronization Therapy (CRT)

... The procedure to put in a resynchronization device is a little more complicated than putting in a regular pacemaker or defibrillator. The extra or third wire required is usually positioned in a very small vein that goes to the left side of the heart. Although most people have a vein that can be used ...
Nursing and heart failure
Nursing and heart failure

... Congestive Heart Failure (CHF) or cardiac failure, is one of the most common causes of in-hospital mortality for patients with cardiac diseases. It is the second most common complication after myocardial infarction (MI). Men are affected more than women. The 5 year mortality rate for men is 60% and ...
Response to (resynchronization) therapy in chronic heart failure
Response to (resynchronization) therapy in chronic heart failure

... patients with greatest ‘benefit’, it is often forgotten that stability or a slowing of deterioration is a powerful effect of modern treatment for CHF but is impossible to observe from non-randomized longitudinal cohort studies. Cohort studies are also unable to address the ‘ceiling effect’ commonly ...
Battery Longevity in Cardiac Resynchronization
Battery Longevity in Cardiac Resynchronization

Perioperative Management of Geriatric Patients with End
Perioperative Management of Geriatric Patients with End

... meet metabolic demands. Initially, the left ventricular end-diastolic volume increases, which causes an improvement in pump function and cardiac output via the Starling mechanism. As the left ventricle dilates and hypertrophies, a change in its geometry occurs, and it becomes more spherical (ventric ...
the Fact Sheet
the Fact Sheet

... Read the manual thoroughly before using the S-ICD System to avoid damage to the pulse generator and/or subcutaneous electrode. Such damage can result in patient injury or death. For single patient use only. Do not reuse, reprocess, or resterilize. All Boston Scientific S-ICD implantable components a ...
The After-Care of Patients with Implanted Cardiac Pacemakers
The After-Care of Patients with Implanted Cardiac Pacemakers

... Instruction of the patient is an important aspect of the after-care. Patients with implanted pacemakers must be taught to check their pulse rate at least daily. Any change of more than four beats in either direction of the set rate of the pulse generator must be immediately reported and investigated ...
Haron kirikiru Effects of inotropics on contractility of the heart
Haron kirikiru Effects of inotropics on contractility of the heart

... Inotropic agents are substances that change the force of muscular contraction, either positively or negatively. Factors that increase contractility are termed as positive inotropic agents. They typically stimulate Calcium ions entry into cardiac muscle cells increasing the force and duration of vent ...
PDF
PDF

... to left ventricular reverse remodelling and improve systolic ventricular function.19 In a retrospective study, Schau et al. could demonstrate that CCM therapy is safe, as it has no adverse effect on long-term survival.20 A small case series demonstrated that the combination of CCM therapy in additio ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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