• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
01 Basic Cardiology
01 Basic Cardiology

... ST segment changes = damage to ventricular muscle ...
Selective Ventricular Chamber Enlargement
Selective Ventricular Chamber Enlargement

... Heart N. Sharp Memorial ...
as a PDF
as a PDF

... is to compare QT dynamicity in patients with ischemic heart disease and in the Long QT Syndrome (LQTS) patients, where abnormal myocardial repolarisation is strictly defined. In this pilot study 29 individuals were investigated. In 7 of them (3 males, 4 females) a KCNQ1 gene mutation was found; 9 pa ...
Beta-Blockers and Heart Failure
Beta-Blockers and Heart Failure

... re-establishing the activity of beta-1 receptors (up-regulation), resulting in greater cardiac sensitivity to NE.2 This could help re-establish myocardial contractility, but may equally aggravate NE toxicity. It is still not clear, therefore, whether the difference in carvedilol properties on the on ...
Heart Lab Questions
Heart Lab Questions

... 2. What is the muscular layer of the heart is called? 3. What is the name of the sac surrounding the heart? 4. What is the function of the heart? 5. What is the function of an artery? 6. What is the function of a vein? 7. What is the specific space in the thoracic cavity where the heart is located? ...
Heart
Heart

... • no direct interconnection between the atrial and ventricular muscle groups. • intricate communication pathway to communicate between the two areas ...
Mechanism of Cardiac Muscle Contraction
Mechanism of Cardiac Muscle Contraction

... the sinus node to the atrioventricular (A-V) node; • The impulse from the atria is delayed in A-V node, before passing into the ventricles; • A-V bundle conducts Impulse from the atria into ventricles; • Left and right bundle branches of purkinje fibers, conduct the cardiac impulse to all parts of v ...
Mechanism of Cardiac Muscle Contraction
Mechanism of Cardiac Muscle Contraction

... the sinus node to the atrioventricular (A-V) node; • The impulse from the atria is delayed in A-V node, before passing into the ventricles; • A-V bundle conducts Impulse from the atria into ventricles; • Left and right bundle branches of purkinje fibers, conduct the cardiac impulse to all parts of v ...
Effects on Heart Rate and Cardiac Output on Model Heart When
Effects on Heart Rate and Cardiac Output on Model Heart When

... The purpose of this project is to explore what happens to the heart rate and the cardiac output in hearts that have atherosclerosis in the aorta and valve disease on the mitral valve Methods/Materials A model heart was constructed from bottles, tubes, car valves and fountain pumps to carry out this ...
Focus on Vastarel MR - Heart and Metabolism
Focus on Vastarel MR - Heart and Metabolism

... acid oxidation and preserving ATP production at the cellular level and thereby reducing intracellular acidosis, influence these overlapping pathogenetic processes in ischemic heart failure. Several data show that myocardial contractile dysfunction in patients with heart failure is conditioned by the ...
CARDIO – Conditions and Medications
CARDIO – Conditions and Medications

... attack) occurs when lack of O2 causes heart muscle to die • Patient squirms to get comfortable, different from angina, pain into left arm, sweat ...
Cardiac Disorders
Cardiac Disorders

... Figure 35-22 ...
Trends Amongst Implantable Cardioverter Defibrillator Patients in a
Trends Amongst Implantable Cardioverter Defibrillator Patients in a

... increased risk of sudden cardiac death. The relative risk reduction in mortality range from 23% at 5 years for primary prevention patients in the SCD-HeFT trial1 to 39% at one year for the secondary prevention patients in the AVID trial.2 Current guidelines of all major cardiac societies in North Am ...
The_Heart_and_Cardiac_Cycle
The_Heart_and_Cardiac_Cycle

...  Time to find our pulse!! - You can find your pulse ...
Atrial Septal Defect with Atrioventricular Block – an
Atrial Septal Defect with Atrioventricular Block – an

... NKX2-5-related ASDs affect males and females equally (1,8). ...
Anatomy Review: The Heart
Anatomy Review: The Heart

... __ b. Convey the action potential to the contractile cells of the ventricle. __ c. Delays the action potential while the atria contract. __ d. Links the SA node to the AV node, distributing the action potential to the contractile cells of the atria. __ e. Electrically connects the atria and the vent ...
as a PDF - Puerto Rico Health Sciences Journal
as a PDF - Puerto Rico Health Sciences Journal

... The aim of this study was to describe the experience at the HFTC-CCPRC implementing a model of DMP to a Hispanic population afflicted by HF. We found significant improvement in several parameters, including NYHA functional class, LVEF, and hospitalization rate after intervention at the HFTC-CCPRC. A ...
Diapositiva 1
Diapositiva 1

... point, ranges from 40% to 50% of patients. Thus, assumed responder rate is estimated at 60% in this patient population  The DSE responder-nonresponder ratio is estimated to be 3:1  It is estimated that demonstration of LVCR using DSE (DSE-positive) will increase CRT responder rate by 20% compared ...
Long Distance Runner with Dilated Cardiomyopathy and Excellent
Long Distance Runner with Dilated Cardiomyopathy and Excellent

... response of muscle blood flow during handgrip exercise were within the normal range. Previous studies have consistently shown that both the levels of sympathetic outflow and muscle blood flow are directly associated with the severity of left ventricular dysfunction. Why was this association not seen ...
Icd 10 code for congestive heart failure with preserved ejection fraction
Icd 10 code for congestive heart failure with preserved ejection fraction

... Icd 10 code for congestive heart failure with preserved ejection fraction Icd 10 code for congestive heart failure with preserved ejection fraction High ventricular filling pressures stimulate the release of ANP and BNP. Both peptides have diuretic, natriuretic, and antihypertensive effects, which t ...
- SCHHS Emergency Department
- SCHHS Emergency Department

... i. narrow complex regular ii. narrow complex irregular iii. wide complex regular iv. wide complex irregular v. torsade des pointes vi. ventricular fibrillation iv) Ectopy i. narrow complex ii. wide complex v) Accessory pathways i. Wolff-Parkinson-White syndrome ii. other vi) Electrophysiological tes ...
pdf Arctic Front Advance™ Cardiac Cryoballoon
pdf Arctic Front Advance™ Cardiac Cryoballoon

... About the Medtronic Arctic Front Advance System The Arctic Front Advance System has been used to treat more than 160,000 patients in 1,000 centers across more than 50 countries. The technologies currently offered include:  The Arctic Front Advance Cryoablation Catheter, used to isolate the pulmonar ...
Medical Coverage Policy Wearable and Portable Cardioverter
Medical Coverage Policy Wearable and Portable Cardioverter

... Sudden cardiac arrest (SCA) is the most common cause of death in patients with coronary artery disease. The implantable cardioverter-defibrillator (ICD) has proven effective in reducing mortality for survivors of SCA and for patients with documented malignant ventricular arrhythmias. More recently, ...
Congential heart disease
Congential heart disease

... The American Heart Association recently updated its guidelines regarding which patients should take a precautionary antibiotic to prevent infective endocarditis (IE) before a trip to the dentist. The guidelines, published in Circulation: Journal of the American Heart Association ,are based on a grow ...
Congential heart disease
Congential heart disease

... The American Heart Association recently updated its guidelines regarding which patients should take a precautionary antibiotic to prevent infective endocarditis (IE) before a trip to the dentist. The guidelines, published in Circulation: Journal of the American Heart Association ,are based on a grow ...
< 1 ... 593 594 595 596 597 598 599 600 601 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report