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Cardiac System
Cardiac System

... a. starts at the SA node (normally 60-80 beats/ minute in an adult), travels down the intranodal pathways to the AV node (can generate 40-60 beats a minute if the SA node is unable), where it pauses briefly to allow contraction and emptying of the atria into the ventricles before contraction of the ...
Effects of PPV on the Cardiovascular, Cerebral, Renal and other
Effects of PPV on the Cardiovascular, Cerebral, Renal and other

... Martti Tenhu, chief medical examiner in Helsinki, Finland, illustrates the differences between a normal human heart and one enlarged by alcoholism and high blood pressure. Covered in scar tissue, the enlarged organ is nearly twice the normal size. Such alcoholic cardiomyopathy weakens the heart so ...
Managing the Hemodynamically Unstable Patient
Managing the Hemodynamically Unstable Patient

... We examined the effects of postoperative nesiritide infusion on hemodynamic and renal function in a prospective open-label study on patients with CHF undergoing cardiac surgery, and found that it induced a significant diuresis in the first 12 hrs13. Subsequently, we participated in a multicenter ran ...
The effect of music on heart Rate
The effect of music on heart Rate

...  Can always be supplemented by ...
Cardiac Defects: Hypoplastic Left Heart Syndrome
Cardiac Defects: Hypoplastic Left Heart Syndrome

... diagnostic tests between the planned stages of surgery, and throughout childhood. Additional surgical or catheter therapies, or in rare cases heart transplantation, may also be recommended. ...
Anatomy, physiology and pharmacology of the autonomic
Anatomy, physiology and pharmacology of the autonomic

... node) nerves (CN X) which provide cervical cardiac nerves to the cardiac plexus. • Unlike the sympathetic innervation, which must first synapse within chain ganglia to supply the heart with postsynaptic (postganglionic) fibres, the parasympathetic fibres synapse at ganglia located directly on the he ...
UCLA Cardiovascular Center uses team approach to
UCLA Cardiovascular Center uses team approach to

... evaluation and the most sophisticated care, including advanced treatment options not widely available elsewhere. For example, UCLA has played a major role in the use of ventricular assist devices (VADs), often testing the newest devices before they are approved for general use. VADs can prolong the ...
here are mcqs from c - lgh
here are mcqs from c - lgh

... rr) reversed splitting of second heart sound - left bundle branch block ss) fourth heart sound--atrial fibrillation In patients with atrial fibrillation (AF) tt) aspirin therapy alone does not reduce the risk of stroke uu) the radial pulse is typically irregularly irregular vv) the response in cardi ...
Systolic vs. Diastolic Heart Failure, is there a difference?
Systolic vs. Diastolic Heart Failure, is there a difference?

... • 50 % of patients had normal EF (ie, HF-PEF) • Patients with HFpEF had following clinical characteristics compared to those with systolic dysfunction: • More likely to be older, female, and hypertensive • Less likely to have had a prior myocardial infarction • Lower in-hospital mortality (3 versus ...
Stable Ischemic Heart Disease - American College of Cardiology
Stable Ischemic Heart Disease - American College of Cardiology

... Caution with aggressive BP management - excessive reduction in diastolic pressure has not been shown to improve outcomes and has been associated with an increase in mortality (reduced coronary perfusion?) Caution with nicotine dependence therapy - worsening of existing depression and the risk for su ...
Who Are the Super-Responders to Cardiac Resynchronization
Who Are the Super-Responders to Cardiac Resynchronization

... high-dose loop diuretics (p = 0.087). Regarding the type of cardiopathy, no differences were observed when comparing the three types simultaneously (dilated cardiomyopathy – DCM, Chagasic cardiomyopathy and ischemic cardiomyopathy). When DCM vs. other cardiomyopathies were analyzed together, the SR ...
Heart PPT #2 - Blair Community Schools
Heart PPT #2 - Blair Community Schools

... •  Membrane potential slowly drifts toward the threshold (-55) ...
Two proteins control the growth of the heart and its adaptation to
Two proteins control the growth of the heart and its adaptation to

contraception for patients with congenital heart disease
contraception for patients with congenital heart disease

... Unplanned pregnancy can be disastrous for patients with congenital heart defects. It is vital that they are given adequate and accurate advice about which forms of contraception are suitable for them. The contraceptive efficacy of each different method must be given consideration. EMERGENCY ‘MORNING ...
Bradyarrhythmias Differential diagnosis of bradyarrhythmias First
Bradyarrhythmias Differential diagnosis of bradyarrhythmias First

... o Gradually increase until both electrical capture (QRS complex after each pacing stimulus) and mechanical capture (palpable pulse corresponding to each QRS complex) are achieved  Once capture achieved, increase the ampage by 10mv to ensure capture. o This is only a temporary intervention an arrang ...
Emergency-Bradyarrhythmias
Emergency-Bradyarrhythmias

... o Gradually increase until both electrical capture (QRS complex after each pacing stimulus) and mechanical capture (palpable pulse corresponding to each QRS complex) are achieved  Once capture achieved, increase the ampage by 10mv to ensure capture. o This is only a temporary intervention an arrang ...
A1981LB38400001
A1981LB38400001

... PEP/LVET, as a convenient quantitative expression of the overall changes in systolic intervals accompanying left ventricular decompensation. This PEP/LVET ratio is now the most commonly applied measure of systolic time intervals for the evaluation of global left ventricular function in man. It was i ...
Physiology: Lecture Study Guide (muscle - Faculty Websites
Physiology: Lecture Study Guide (muscle - Faculty Websites

... 6. Describe the sequence of the conduction system through the heart. What nodal tissues are involved? Which nodal tissue sets the normal heart rate? How is heart rate affected if the pacemaker is damaged? 7. What is represented by the P-wave, QRS-complex, and T wave on an electrocardiogram? 8. What ...
Diastolic congestive heart failure: Treatment is moving to the `burbs
Diastolic congestive heart failure: Treatment is moving to the `burbs

... Typical exercise was 30 minutes per day, 3 times a week at an intensity based on previous exercise stress test with a duration of 12-24 weeks ...
Cobalt cardiomyopathy: clinical aspects - Heart
Cobalt cardiomyopathy: clinical aspects - Heart

... found in fasting subjects within four days cava, and the more severe it was the graver the (Haro, Brin, and Faloon, I966). Virological prognosis. The pulmonary arteries were diland immunological studies were negative. ated in half of the cases, and passive congesSearch for toxic substances such as a ...
AP150 HEART IMAGES--post
AP150 HEART IMAGES--post

... – desmosomes: tightly bind cells & transfer of tension – gap junction: electrical synapses that directly transfer electrical activity/AP from one cell to the next • Contractile/myocardial Cells (myocytes) => contract and conduct AP’s • Conductile/autorhythmic cells => produce and conduct action pote ...
CardiacStudent - Union City High School
CardiacStudent - Union City High School

... _________________ (Creatine Phosphokinase) – found in brain and muscle tissue. Elevated in MI 3-6 hours after infarction; peaks in ___________ hours.  _____________ (Lactic Dehydrogenase) – produced during Krebs cycle. Elevated ___________ days after heart attack  _____________- early detection. E ...
1-Wall of the heart and cardiac
1-Wall of the heart and cardiac

... – Less abundant SR. (SR = Sarcoplasmic Reticulum) – T-tubules come in contact with only one cisterna of SR forming “Diads” (not triads). – Glycogen & myoglobin. ...
A1984SB92000001
A1984SB92000001

... then already in existence, but most were handling blood outside the body. The intra-aortic balloon did not require an extracorporeal blood circuit. Instead of drawing the blood outside the body durins ventricular systole and pumping it back during diastole, as was done by Harken, we introduced a lon ...
Minimum Question Cardiology and Angiology Year IV. 2016 1. The
Minimum Question Cardiology and Angiology Year IV. 2016 1. The

... 63. Criteria of diastolic dysfunction a, normal ejection fraction, diastolic dysfunction, enlarged left atrium, left ventricular hypertrophy b, reduced ejection fraction, normal chamber sizes, normal pressure in the left atrium c, normal chamber sizes, reduced right ventricular function d, any of a ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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