IMPROVE HF Primary Results
... – Reasons for preventing treatment may not have been documented – NYHA was not quantified in many records and instead was based on qualitative description of the patient’s functional status • Potential for ascertainment bias – Self-selected cardiology practices, primary care setting not included • N ...
... – Reasons for preventing treatment may not have been documented – NYHA was not quantified in many records and instead was based on qualitative description of the patient’s functional status • Potential for ascertainment bias – Self-selected cardiology practices, primary care setting not included • N ...
METHODS ONLINE ONLY
... Thirty-six (n=36) farm pigs of either sex weighing 38±2 kg were used in the study. Animals were kept and handled in accordance with the recommendations of the “Guide for the Care and Use of Laboratory Animals” published by the US National Institutes of Health (NIH Publication No. 85-23, Revised 1996 ...
... Thirty-six (n=36) farm pigs of either sex weighing 38±2 kg were used in the study. Animals were kept and handled in accordance with the recommendations of the “Guide for the Care and Use of Laboratory Animals” published by the US National Institutes of Health (NIH Publication No. 85-23, Revised 1996 ...
Patients with implantable cardioverter defibrillator shocks: what is
... Summary II The burden of ICD-shock patients is increasing due to increasing implantation rates. Fortunately, modern empiric programming of ATP and detection algorithms results in a marked reduction of the individual risk of suffering from shocks. However, appropriate and possibly even inappropriate ...
... Summary II The burden of ICD-shock patients is increasing due to increasing implantation rates. Fortunately, modern empiric programming of ATP and detection algorithms results in a marked reduction of the individual risk of suffering from shocks. However, appropriate and possibly even inappropriate ...
Cardiac Case Studies Due: Jan. 22 Scenario #1 (15 questions) M.G.
... When you first admitted G.P., you placed him on telemetry and observed this cardiac rhythm. ...
... When you first admitted G.P., you placed him on telemetry and observed this cardiac rhythm. ...
ACUTE PERICARDITIS
... Many believe that prednisone may perpetuate recurrences Intrapericardial glucocorticoid therapy: sx improvement and prevention of recurrence in 90% of patients at 3 months and 84% at one year ...
... Many believe that prednisone may perpetuate recurrences Intrapericardial glucocorticoid therapy: sx improvement and prevention of recurrence in 90% of patients at 3 months and 84% at one year ...
Institute of Cardio-Vascular Diseases
... cardiac auscultation. She had been suffering from rheumatoid arthritis since 25 years. Chest X-ray and ECG showed features of biatrial enlargement. The echocardiogram revealed biatrial enlargement, preserved systolic and diastolic function, normal pulmonary artery systolic pressures, interventricula ...
... cardiac auscultation. She had been suffering from rheumatoid arthritis since 25 years. Chest X-ray and ECG showed features of biatrial enlargement. The echocardiogram revealed biatrial enlargement, preserved systolic and diastolic function, normal pulmonary artery systolic pressures, interventricula ...
Episode overview: Congestive heart failure
... 4 For instance, heart failure medications for systolic dysfunction are optimized for neurohormonal blockade using beta-blockers, ACE inhibitors or ARBs, and aldosterone antagonists; these same kinds of medications are used for diastolic dysfunction, albeit for different reasons (e.g., rate control w ...
... 4 For instance, heart failure medications for systolic dysfunction are optimized for neurohormonal blockade using beta-blockers, ACE inhibitors or ARBs, and aldosterone antagonists; these same kinds of medications are used for diastolic dysfunction, albeit for different reasons (e.g., rate control w ...
Objectives Multiple Choice
... One of the important differences between skeletal muscle tissue and cardiac muscle tissue is that cardiac muscle tissue is: comprised of unusually large cells multinucleated striated voluntary muscle striated involuntary muscle none of the above ...
... One of the important differences between skeletal muscle tissue and cardiac muscle tissue is that cardiac muscle tissue is: comprised of unusually large cells multinucleated striated voluntary muscle striated involuntary muscle none of the above ...
New conduction defects and pacemaker implantation after heart
... implantation. In case of symptomatic bradycardia requiring prolonged temporary pacing, theophylline was administered before PPM implantation. There were no significant differences in cardiac ischemic time, CPB time duration, baseline pulmonary vascular wedge pressure, and the mean pulmonary arterial ...
... implantation. In case of symptomatic bradycardia requiring prolonged temporary pacing, theophylline was administered before PPM implantation. There were no significant differences in cardiac ischemic time, CPB time duration, baseline pulmonary vascular wedge pressure, and the mean pulmonary arterial ...
beta-blockers: Are they useful in arrhythmias?
... more effective in this regard.6 Beta-blockers are however, fairly good in the prevention of these tachycardias on a long-term basis. However, beta-blockers have been ineffective and contraindicated in the treatment of multifocal atrial tachycardia is frequently associated with severe obstructive lun ...
... more effective in this regard.6 Beta-blockers are however, fairly good in the prevention of these tachycardias on a long-term basis. However, beta-blockers have been ineffective and contraindicated in the treatment of multifocal atrial tachycardia is frequently associated with severe obstructive lun ...
Cardiac Cycle
... The QRS wave represents the depolarization event of the ventricles and the Tdeflection, the ventricular repolarization. Thus, the time period between the de- and the beginning of the T repolarization wave is the prolonged depolarization seen as the plateau phase of the ventricular action potential. ...
... The QRS wave represents the depolarization event of the ventricles and the Tdeflection, the ventricular repolarization. Thus, the time period between the de- and the beginning of the T repolarization wave is the prolonged depolarization seen as the plateau phase of the ventricular action potential. ...
morphometric study of trabecula septomarginalis in
... reported by Leão et al. (2010). However, this finding differs from the report by Depreux et al. (1976), who stated that this arrangement occurred only between the muscle and the stimulation complex branch in the trabeculae septomarginalis that presented in their constitution muscle tissue and not in ...
... reported by Leão et al. (2010). However, this finding differs from the report by Depreux et al. (1976), who stated that this arrangement occurred only between the muscle and the stimulation complex branch in the trabeculae septomarginalis that presented in their constitution muscle tissue and not in ...
Repolarisation Descriptors and Heart Rate Variability in
... Patients with obstructive coronary artery disease were eligible if they had been asymptomatic and free of any cardiac events for at least 12 months before the first recording. Patients with fasting plasma glucose ≥7.0 mmol/l and/or A1C≥6.5 percent (48 mmol/mol) ...
... Patients with obstructive coronary artery disease were eligible if they had been asymptomatic and free of any cardiac events for at least 12 months before the first recording. Patients with fasting plasma glucose ≥7.0 mmol/l and/or A1C≥6.5 percent (48 mmol/mol) ...
ventricular ectopic beats and exercise
... infarction, PVCs once considered to presage the onset of VF, such as those occurring close to the preceding T wave, more than five or six per minute, bigeminal or multiform complexes, or those occurring in salvoes of two or three or more, do not occur in about 50% of patients in whom VF develops, an ...
... infarction, PVCs once considered to presage the onset of VF, such as those occurring close to the preceding T wave, more than five or six per minute, bigeminal or multiform complexes, or those occurring in salvoes of two or three or more, do not occur in about 50% of patients in whom VF develops, an ...
Pathophysiology of Heart Failure
... A. Otto Frank (1899) is credited with the seminal observation that peak ventricular pressure increases as the end-diastolic volume is increased. This observation was made in an isolated frog heart preparation in which ventricular volume could be measured with relative ease. Though of primary importa ...
... A. Otto Frank (1899) is credited with the seminal observation that peak ventricular pressure increases as the end-diastolic volume is increased. This observation was made in an isolated frog heart preparation in which ventricular volume could be measured with relative ease. Though of primary importa ...
4.Prasanna Mahendra Sapkal, Prasanna Deepak Madane
... Heart failure may be either predominantly systolic and diastolic. Patient with systolic heart failure also have some amount of diastolic dysfunction(1). Diastolic heart failure: Patient with diastolic heart failure are typically elderly, often female, obese and frequently have hypertension and diabe ...
... Heart failure may be either predominantly systolic and diastolic. Patient with systolic heart failure also have some amount of diastolic dysfunction(1). Diastolic heart failure: Patient with diastolic heart failure are typically elderly, often female, obese and frequently have hypertension and diabe ...
The 2014 American College of Cardiology ACC/American Heart
... 5. An algorithm (Figure 1) details the components of an early invasive strategy or an ischemia-guided strategy. An early invasive strategy is indicated for patients with refractory angina or hemodynamic or electrical instability and those at elevated risk for clinical events. An early invasive stra ...
... 5. An algorithm (Figure 1) details the components of an early invasive strategy or an ischemia-guided strategy. An early invasive strategy is indicated for patients with refractory angina or hemodynamic or electrical instability and those at elevated risk for clinical events. An early invasive stra ...
ECG Leads
... the endocardial surface of the posterior wall of the left ventricle. As these leads record from the opposite side of the heart instead of directly over the infarct, the changes of posterior infarction are reversed in these leads. The R waves increase in size, becoming broader and dominant, and are a ...
... the endocardial surface of the posterior wall of the left ventricle. As these leads record from the opposite side of the heart instead of directly over the infarct, the changes of posterior infarction are reversed in these leads. The R waves increase in size, becoming broader and dominant, and are a ...
Incidence of Atrial Fibrillation in Patients with either Heart Failure or
... the cumulative incidence of new-onset AF was 9.6% (placebo group), and the cumulative incidence 6 months following hospitalization was 6.8%. Our long term result corresponds very well with the findings of recent studies. However we used a competing risk analysis to estimate cumulative risks which is ...
... the cumulative incidence of new-onset AF was 9.6% (placebo group), and the cumulative incidence 6 months following hospitalization was 6.8%. Our long term result corresponds very well with the findings of recent studies. However we used a competing risk analysis to estimate cumulative risks which is ...
Cardiac extracellular matrix: a dynamic entity
... cardiac fibrosis by angiotensin II or deoxycorticosterone acetate. Furthermore, angiotensin II and transforming growth factor-1 enhanced the synthesis of fibrillin by cardiac fibroblasts. These results strongly suggest that fibrillin is an important component of the extracellular matrix of the myoc ...
... cardiac fibrosis by angiotensin II or deoxycorticosterone acetate. Furthermore, angiotensin II and transforming growth factor-1 enhanced the synthesis of fibrillin by cardiac fibroblasts. These results strongly suggest that fibrillin is an important component of the extracellular matrix of the myoc ...
Heart surgery
... throughout the body are dependent on the precise functioning of the heart's electrical system. Unfortunately, the heart's electrical system can malfunction, heart rates become irregular and not enough blood is pumped through the body. There are many reasons for the heart to “misfire” and require pac ...
... throughout the body are dependent on the precise functioning of the heart's electrical system. Unfortunately, the heart's electrical system can malfunction, heart rates become irregular and not enough blood is pumped through the body. There are many reasons for the heart to “misfire” and require pac ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.