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Prognostic Markers for Coma and Disorders of Consciousness
Prognostic Markers for Coma and Disorders of Consciousness

... on timing: in an ideal world, patients with terminal illness or elderly patients have already discussed with their family and family physician what can be expected in quality of life in case of an unexpected event and therefore have put an advanced medical directive with or without a DNR (do not res ...
Complete Revascularization in Patients with Severe Left Ventricular
Complete Revascularization in Patients with Severe Left Ventricular

... Patients with poor LV function caused by coronary artery disease increasingly have a third treatment option; myocardial revascularization. Cardiac transplantation is very effective, but limited by donor availability,6,11) and medical treatment of such patients is associated with poor results.5) As m ...
General Heart Failure
General Heart Failure

... Class III ...
Features of Heart Rate Variability and Early Postinfarction
Features of Heart Rate Variability and Early Postinfarction

NOTES Mod #4 Heart Failure/Pulmonary Edema
NOTES Mod #4 Heart Failure/Pulmonary Edema

CARDIAC POWER OUTPUT, ITS ROLE IN DEFINING HEART
CARDIAC POWER OUTPUT, ITS ROLE IN DEFINING HEART

... capability cannot produce the contractile energy the arterial system requires to support circulation(1). At this point clinicians intervene with pharmacological agents to increase cardiac function and reduce HF symptoms. As HF progresses and patients become nonresponsive to medical management, a hem ...
HOPE
HOPE

... HOPE: Dose-dependent effects of ramipril on LV mass and function Mean baseline LVEF 58% in all groups ...
Low Dose Fibrinolytic Therapy for Treating Right Heart Thrombus
Low Dose Fibrinolytic Therapy for Treating Right Heart Thrombus

... hydrochlorthiazide and Nifedipine for hypertension. She had no history of other chronic diseases. She had mild dyspnoea, on physical examination her blood pressure was 90/50 mmhg , a pulse rate of 120 beat/minute , cardiovascular examination revealed irregular first and second heart sounds, with sys ...
1 Mechanisms of chronic heart failure development
1 Mechanisms of chronic heart failure development

... 1990) and in ESRD patients(Silberberg 1989). In the latter population, LVH is principally due to an increased demand in the left ventricular minute work resulting from volume/flow and pressure overload (Meeus et al.1989). Two forms of the left ventricular hypertrophy could be present and are relativ ...
ON THE STRUCTURE OF THE SNAIL`S HEART. By
ON THE STRUCTURE OF THE SNAIL`S HEART. By

... much stronger, less granular, broader, and more easily isolated, than those of the heart. In some specimens the striation is perfectly clear, distinct light -and dark bands alternating with each other with perfect -regularity. In others again the muscle cells appear simply granular with Hartnack No. ...
Cardiac Arrhythmias in the Intensive Care Unit
Cardiac Arrhythmias in the Intensive Care Unit

... on the AV node. It controls resting heart rates in patients who do not have increased catecholamine levels but is less effective in the ICU. IV digoxin begins to slow the heart rate in 30 minutes.18 Cardioversion of a patient with AF carries a stroke risk from 1.1% if anticoagulated for 3 weeks to 7 ...
Waon Therapy for Cardiovascular Disease
Waon Therapy for Cardiovascular Disease

... the prognosis of 129 patients with CHF: 64 underwent Waon therapy, 65 did not, and the patients were followed for 5 years. The patients in the Waon group continued the therapy at least twice weekly after discharge. Waon therapy significantly decreased the rate of death or hospitalization in patients ...
Trimetazidine and left ventricular ischaemic dysfunction: an
Trimetazidine and left ventricular ischaemic dysfunction: an

... Twenty patients with severe ischaemic cardiomyopathy (class III and IV of the New York Heart Association [NYHA]) treated with classic combination therapy were randomized to either placebo or trimetazidine 20 mg three times daily. Ejection fraction at rest was assessed by radionucleide angiography an ...
Arrhythmias During the 1st Week of Acute Myocardial Infarction: An
Arrhythmias During the 1st Week of Acute Myocardial Infarction: An

... Introduction: Though the management of coronary artery disease is more advanced now a days. It is still having higher incidence, morbidity, and mortality. The mortality and morbidity are mainly due to the development of arrhythmias. Materials and Methods: We prospectively studied the clinical, labor ...
Implantable Cardiac Loop Recorders
Implantable Cardiac Loop Recorders

... Implantable loop recorders (ILRs) have been proposed as a diagnostic option for identifying cardiac dysrhythmias. The ILR is implanted subcutaneously, requiring the procedure to be performed in an ambulatory surgical site under aseptic conditions. The ILR provides continuous loop storage of cardiac ...
FRACP- Cardiology answers
FRACP- Cardiology answers

... Aortic valve replacement surgery is recomended prior to routine surgery in patient with severe AS who are candidates for valvular surgery. Only one study has been published on the outcome of patients with severe aortic stenosis who underwent non-cardiac surgery. They did remarkably well with careful ...
Microvolt T-wave Alternans - the Sudden Cardiac Arrest Association
Microvolt T-wave Alternans - the Sudden Cardiac Arrest Association

... angiography  should  not  be  delayed.    As  such,  MTWA may be used to enhance the diagnostic yield  of traditional stress testing.  ...
Heart Part 2 - biologyonline.us
Heart Part 2 - biologyonline.us

... vehicular accident can produce a tear in the aorta tear is just distal to the great vessels the tear leads to sudden loss of blood and shock It is widely believed that ...
AAFP Board Review: Managing Dysrhythmias
AAFP Board Review: Managing Dysrhythmias

... shortness of breath and a feeling of general weakness. His symptoms have developed over the past 24 hours. On physical examination you find a regular pulse with a rate of 160 beats/min. You note rales to the base of the scapula bilaterally, moderate jugular venous distention, and hepatojugular reflu ...
Title
Title

... Pacing and Cardioverter-Defibrillators, two years of data were collated from the two major implanting teams in Trinidad for the years 2005 and 2009 respectively. The two implanting centres were the Advanced Cardiovascular Institute (ACI), which is now based at Westshore Medical Centre (formerly at S ...
Heart Starter - The Royal College of Pathologists of Australasia
Heart Starter - The Royal College of Pathologists of Australasia

... solely upon BNP measurement. Interestingly, the BNP gene contains a destabilising sequence that suggests the release and breakdown of BNP is relatively rapid, with the hormone synthesised in bursts in response to ventricular overload. “The initial studies used in the general practice setting used BN ...
Slide 1
Slide 1

... Mutations in several genes encoding ion channels, especially SCN5A, have emerged as the basis for a variety of inherited cardiac arrhythmias. ...
Off-Pump Plication of Post MI Left Ventricular Aneurysm
Off-Pump Plication of Post MI Left Ventricular Aneurysm

... • LVA - common complication of MI. • CASS definition- LV aneurysm is the segment of the LV wall protruding from the expected outline of the ventricular chamber and displaying either akinesis or dyskinesis. • Aneurysms distort LV elliptical geometry → ↓ LV ejection volume → cardiac failure. • Medical ...
Are premature ventricular contractions in patients without apparent
Are premature ventricular contractions in patients without apparent

... determinant of LV dysfunction. PVCs with longer QRS duration seem to be associated with worsening LV function and in these patients ablation leads to LV improvement (17). Mechanisms proposed for PVC-mediated LV dysfunction include alterations in calcium homeostasis, increased oxygen consumption, and ...
PHYSICAL FITNESS AND CARDIOVASCULAR ENDURANCE
PHYSICAL FITNESS AND CARDIOVASCULAR ENDURANCE

... • Cardio - the heart – about the size of a fist • The Heart – a hollow organ containing 4 chambers • Septum – wall which divides the heart cavity into a “right heart” & a “left heart” • Right Atrium/Left Atrium – holding tanks for the blood ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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