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Periodicities of cardiac mechanics
Periodicities of cardiac mechanics

... of the contracting myocardium, such as the calcium flux (2, 3), whereasothers have suggestedthat oscillations of the venous return or the afterload are responsible for these mechanical periodicities (5,6,12,14,17,26). Because the mechanical action of the heart can be describedby its pressure-volumer ...
Antiarrhythmic pharmacotherapy
Antiarrhythmic pharmacotherapy

... - give sotalol IV, 1.5mg/kg (so, about 100mg for a normal-sized person) - then, prepare for elective cardioversion. If its not working, give another 0.5mg/kg sotalol. If its still; not working, you need to move on to IV lignocaine as a 1mg/kg bolus, delivered slowly. You may attempt an infusion. Thi ...
Measuring Technology for Cardiac Magneto-field Using
Measuring Technology for Cardiac Magneto-field Using

... information about the heart activity, structure, and blood flow. FECG using an electrode placed on the mother’s abdomen provides electrophysiological information such as arrhythmia or detects for variations in the heart beat. Fetal magnetocardiograms (FMCGs), in contrast, can be taken over the abdom ...
Benign Mediastinal Lymphadenopathy in Congestive Heart Failure*
Benign Mediastinal Lymphadenopathy in Congestive Heart Failure*

... diffuse intrathoracic edema affecting the pulmonary parenchyma and neighboring structures, including the mediastinum and associated lymph nodes. The lymphatic circulation has a primary role in the regulation of pulmonary fluids. It ensures continuous low-pressure drainage of excess fluids from the i ...
Atrial Fibrillation in the Heart Failure Population
Atrial Fibrillation in the Heart Failure Population

... management approach to AF in the general cardiology population. The Atrial Fibrillation Follow-up Investigation in Rhythm Management (AFFIRM) trial demonstrated no significant difference in overall mortality between rate control versus rhythm control groups, with both groups receiving anticoagulatio ...
Heart failure - primary care
Heart failure - primary care

... • includes asymptomatic left ventricular systolic dysfunction (LVSD) • ordinary physical activity does not cause fatigue, breathlessness, or palpitation • NYHA class II: • symptomatically 'mild' HF • slight limitation of physical activity • ordinary physical activity may result in fatigue, palpitati ...
MMNN
MMNN

...  Atrial septal defects in which pulmonary flow is increased 50% above systemic flow (i.e. flow ratio of 1.5:1) are often large enough to be clinically recognisable and should be closed surgically. Closure can also be accomplished at cardiac catheterisation ...
POSSIBILITIES OF ALDOSTERONE ANTAGONIST USE IN THE
POSSIBILITIES OF ALDOSTERONE ANTAGONIST USE IN THE

... Obtained results showed, that the presence of concomitant COPD in patients with AH contributes to the development of diastolic dysfunction of LV. After basic treatment hypertrophic type of diastolic dysfunction of LV was detected in 19 (90,4 %) patients and pseudonormal one – in 2 (9,5 %) patients. ...
Treating Congestive Heart Failure in 2007
Treating Congestive Heart Failure in 2007

... enough. Most patients with heart failure will respond well to medication and regain their asymptomatic state when treated. Heart failure is *not* cardiac arrest, even though clients, from watching television, may think so. Therefore, this term should not be used as a first-line description for most ...
The Language of Medicine - Respiratory Therapy Files
The Language of Medicine - Respiratory Therapy Files

... atria just before contraction; • QRS wave = spread of excitation wave over the ventricles as the ventricles contract; • T wave = electrical recovery and relaxation of ventricles. • A heart attack (myocardial infarction or MI) can be recognized by an elevation in the S-T segment of the ECG. ...
treating atrial fibrillation
treating atrial fibrillation

... the upper chambers of the heart (atria) with irregular and often rapid conduction to the lower chambers of the heart (ventricles). It is the most common type of heart rhythm disturbance. In atrial fibrillation, the heartbeat is irregular and rapid. Sometimes the upper chambers beat as often as 300 t ...
Hypokalemia and ST Elevation Induced by Angiotensin II Type 1
Hypokalemia and ST Elevation Induced by Angiotensin II Type 1

... K+ concentration less than 3.5 mmol/L, may result from one (or more) of the following: decreased net intake, shift into cells or increased net loss.11,12 The clinical manifestations of K+ depletion vary greatly between individual patients, and the severity depends on the degree of hypokalemia. In pa ...
atrial_fibrillation_and_atrial_flutter
atrial_fibrillation_and_atrial_flutter

... • Pets with atrial fibrillation have an erratic heart rhythm that sounds like “tennis shoes in a dryer” when listening to the chest with a stethoscope (procedure known as “auscultation”) • Heart sounds when listening to the heart with a stethoscope normally sound like “lub dub”; the first heart soun ...
QA436_1_Bleedingrisks
QA436_1_Bleedingrisks

... regards to the elderly population and put this into context with their stroke risk or risk of developing further thrombotic events. Although elderly patients may have an increased risk of falling, studies have shown that on average only 1 in 10 falls results in major injury or fractures. In addition ...
Prognostic Usefulness of Dyspnea Versus Fatigue
Prognostic Usefulness of Dyspnea Versus Fatigue

... strategy (tidal volume–respiratory rate relation and prolonged inspiratory time to total breath time ratio) have been noted with the onset of dyspnea in patients with HF.10,11 The appearance of rapid and shallow ventilation, respiratory muscle dysfunction, and the accompanying sensation of dyspnea m ...
Atrial Fibrillation and Atrial Flutter
Atrial Fibrillation and Atrial Flutter

... • Pets with atrial fibrillation have an erratic heart rhythm that sounds like “tennis shoes in a dryer” when listening to the chest with a stethoscope (procedure known as “auscultation”) • Heart sounds when listening to the heart with a stethoscope normally sound like “lub dub”; the first heart soun ...
2014 Slide Set - American College of Cardiology
2014 Slide Set - American College of Cardiology

... guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable, there may be a very clear clinical consensus that a particular test or therapy is useful or effective. *Data available from clinical trials or registries about the usefulness/ efficacy in different subp ...
Factors that control the stroke volume are divided into: 1
Factors that control the stroke volume are divided into: 1

... The measurement of preload is proportional to the EDV (which represents the passive tension) or EDP. Whether we said it is proportional to EDV or EDP doesn't matter bcz EDV and EDP are proportional that as the volume of blood increases at the end of diastole, the pressure will increase at the end of ...
Transapical left ventricular access for difficult to reach
Transapical left ventricular access for difficult to reach

... We preferred using 20-cm introducer sheaths for access and deployment of all devices to limit the danger of thrombus formation and air embolism. Attention should also be paid to removal of sheaths from the ventricle. Most of our punctures were surgically closed under direct vision. It was our clinic ...
Cardiac Imaging 2010 - Stritch School of Medicine
Cardiac Imaging 2010 - Stritch School of Medicine

... hypertrophic subaortic stenosis) Autosomal dominant with 0.2% prevalance Presentation – Family history, new murmur, arrhythmia, heart failure, sudden death; most common cause of sudden cardiac death in young ...
More on the right ventricle in pulmonary hypertension Robert Naeije and Stefano Ghio
More on the right ventricle in pulmonary hypertension Robert Naeije and Stefano Ghio

... ejection fraction (RVEF) >25% had better survival than those with a RVEF <25%. Furthermore, patients with a stable or increased RVEF at 3–6 months had a trend to better overall survival and a significantly lower cardiovascular mortality. These results are in keeping with recently demonstrated progno ...
Chapter 18 - Las Positas College
Chapter 18 - Las Positas College

... A. The four heart valves are the two atrioventricular valves and the two semilunar valves. (p. 537, Fig. 18.8) 1. The right AV valve is the tricuspid and the left AV valve is called the bicuspid or mitral. 2. The two semilunar valves are the pulmonary semilunar valve and the aortic semilunar valve. ...
Atrioventricular Reciprocating Tachycardia Mediated by Twin
Atrioventricular Reciprocating Tachycardia Mediated by Twin

... From the Hôpital Cardiologique Haut Lèvéque, CHU Bordeaux, Bordeaux, France. Dr. Frontera received a grant from the European Heart Rhythm Association outside this work. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. ...
Antiarrythmic drugs
Antiarrythmic drugs

... under normal conditions, eg, some Purkinje fibers) are particularly prone to acceleration by the above mechanisms. However, all cardiac cells, including normally quiescent atrial and ventricular cells, may show repetitive pacemaker activity when depolarized under appropriate conditions, especially i ...
provisional programme
provisional programme

... restrictive (rare). Dilated cardiomyopathy would be suspected in a patient presenting with heart failure who did not have a previous history of angina or myocardial infarction. When angiograms are performed, at least 60% of such patients are found to have “silent” coronary disease (ie previously und ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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