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Reducing risk in heart disease
Reducing risk in heart disease

... ‘expert opinion’, based on independent review of the available evidence. Interpretation of this document by those without appropriate medical and/or clinical training is not recommended, other than at the request of, or in consultation with, a relevant health professional. While care has been taken ...
IMPROVE HF Primary Results
IMPROVE HF Primary Results

... Implementation of a defined and scalable practice specific performance improvement intervention enhances use of evidence-based, guideline-recommended HF therapies demonstrated to improve outcomes In all care settings where HF patients are managed, programs to provide practitioners with useful remind ...
Organ preservation with the organ care system
Organ preservation with the organ care system

... 2002 to 2009 donor age increased significantly up to 33 years, whereas between 1992 and 2001 the corresponding value was 31 years. Additionally, donors in Europe are more than 6 years older on average compared to those in North America (1). In this context Russo et al. demonstrated that the effect o ...
Opmaak 1 - UZ Leuven
Opmaak 1 - UZ Leuven

... the available data suggests that spontaneous AV conduction recovery usually does take place within 7 to 10 days. However, late recovery of AV conduction is well recognized. A recovery of AV conduction in 7 in 72 (9.6%) cases of postoperative CHB persisting beyond 14 days was reported by Batra et al. ...
ISACHD Newsletter
ISACHD Newsletter

... well tolerated and effective in improving pulmonary arterial hypertension (PAH) symptoms in patients with Eisenmenger syndrome but data from longer-term studies are lacking. The aim of this study was to retrospectively analyze the long-term efficacy and safety of bosentan in adults with PAH secondar ...
Dyads affected by chronic heart failure: a
Dyads affected by chronic heart failure: a

... leading cause of hospitalization for elderly patients and prognosis is poor with half of the patients dying within 4 years after diagnosis (1). Marital quality has been found to predict survival during an 8-year follow up period (3). Patients’ self-report of having a good marriage (i.e. being marrie ...
Nurses Guide to Commonly asked Questions about Heart Failure
Nurses Guide to Commonly asked Questions about Heart Failure

... Proven medical therapies such as Beta blockers & ACEI‟s have improved survival significantly so that patients can be hopeful for a better quality of life. What are the survival rates? Survival rates are as same as prognosis. What are the treatment options? There are many treatment options for heart ...
Left Ventricular Assist Device as Permanent Support in Patients with
Left Ventricular Assist Device as Permanent Support in Patients with

... Conclusions: Pulsatile LVAD as destination therapy probably increases survival (GRADE ), and may improve the functional capacity (GRADE ) in patients with terminal left ventricular heart failure in comparison with OMT. It is uncertain whether the treatment has any effect on quality of life ( ...
Scoring Center: Scoring Cardiac Dysrhythmias - Part 2
Scoring Center: Scoring Cardiac Dysrhythmias - Part 2

... phenomena, if cells depolarize, then they must then repolarize to prepare for the next depolarization cycle. The T wave of the EKG complex represents repolarization of the ventricle. The waveform associated with repolarization of the atria is not seen because of its low amplitude and its simultaneou ...
Lifetime Analysis of Hospitalizations and Survival of Patients Newly
Lifetime Analysis of Hospitalizations and Survival of Patients Newly

... Methods and Results—We examined recurrent hospitalizations, cardiovascular events, and survival among newly discharged (April 1999–March 2001) patients with HF in the Enhanced Feedback For Effective Cardiac Treatment phase 1 study. During 10-year follow-up, we examined all new cardiovascular hospita ...
Dental considerations in patients with heart disease
Dental considerations in patients with heart disease

... virus (HIV) (17). Recurrent infectious endocarditis is also commonly observed in these individuals (16). Due to the important morbidity and mortality involved, antibiotic prophylaxis is considered necessary when planning dental treatment in individuals at risk (12), though according to Farbod et al. ...
PICOT Paper - WordPress.com
PICOT Paper - WordPress.com

... Strengths of this study include no conflict of interest or biases due to the randomization process, the data is credible and current from 2012, and the study has been published in an international, peer-reviewed journal. This study also included the work of a statistician and results were illustrate ...
Correlation Between Pediatric Open Heart Surgery
Correlation Between Pediatric Open Heart Surgery

... significant correlation between gender and postoperative outcome (P > 0.05).A statistically significant difference was observed between the mean ages of the complicated and the non-complicated groups (4.88 ±3.67 vs. 6.81± 3.89 years, P < 0.05), as the complicated group was generally younger than the ...
Complementary therapies for patients undergoing cardiac surgery
Complementary therapies for patients undergoing cardiac surgery

... positive results its worth to explore this intervention with a larger sample(Salamati, Mashouf, Sahbaei, & Mojab, 2014). Another study evaluated the efficacy of aromatherapy on blood pressure, anxiety, and sleep among patients following the percutaneous coronary intervention. This study concluded th ...
Hyperkalemia
Hyperkalemia

... Progression of QRS duration leading to sine wave pattern Ventricular fibrillation or asystole ...
Inherited Cardiac Arrhythmias
Inherited Cardiac Arrhythmias

... In Brugada syndrome, arrhythmias tend to occur during sleep or with pyrexia (10). The primarily structural cardiac diseases with arrhythmia also often manifest for the first time not in the form of reduced tolerance of stress, but in arrhythmias. Pathognomonic changes may be visible in the resting E ...
Cost-Effectiveness of Implantable Cardioverter Defibrillators in Brazil
Cost-Effectiveness of Implantable Cardioverter Defibrillators in Brazil

... had no history of malignant arrhythmias and the model was established as a primary event prevention one. Description of the clinical-decision model The decision tree, created using the Data Treeage software (release 5.0), was divided in two strategies: defibrillator + conventional therapy versus con ...
Editorial Electromagnetic interference in patients with - Heart
Editorial Electromagnetic interference in patients with - Heart

... to be influenced by EMI, probably because the atrial channels are programmed to be more sensitive in order to sense and respond appropriately to low voltage spontaneous P waves. Oversensing of environmental signals in the atrial channel will cause ventricular paced rhythms. Dual chamber pacemakers a ...
Computational Modeling of Human Fetal Normal Sinus Rhythm and
Computational Modeling of Human Fetal Normal Sinus Rhythm and

... Figure 3. Ratio of ventricular: atrial periodic activity in 1D, 24 WGA model during spatially uniform block of GCaL, estimated during the last 6s of 10s of activity. (Wenckebach-like), and complete conduction block. They can be produced by spatially uniform reduction in the Ltype calcium maximal co ...
Biventricular Takotsubo Cardiomyopathy
Biventricular Takotsubo Cardiomyopathy

... findings, and maximal troponin release. However, patients with biventricular TC had significant reduction in LVEF (0.29 vs 0.42), were hospitalized 4 days longer (11 vs 7 d) on average, presented with notably increased tricuspid regurgitation velocity, and had an increased complication rate in compa ...
heart failure - Chinese Community Health Resource Center
heart failure - Chinese Community Health Resource Center

... which causes the blood vessels to expand, thereby lowering blood pressure and reducing the heart's workload. ACE inhibitors prevent the body from creating angiotensin, a substance in the blood that causes vessels to tighten and blood pressure to rise. Common side effects may include dizziness, cough ...
Tetralogy of Fallot: The evolution of congenital heart surgery
Tetralogy of Fallot: The evolution of congenital heart surgery

... Preoperative hematocrit levels for patients with cyawas around 60%.4 As experience with shunt pronosis could reach as high as 80%, thus, placing them cedures grew and complications related to CPB at risk for thrombosis. Without pulse oximetery, ausdecreased, the awareness of morbidity and mortality ...
Alcoholic Cardiomyopathy: Clinical and Molecular Findings
Alcoholic Cardiomyopathy: Clinical and Molecular Findings

... esters in the alcoholic heart, which can attach to the mitochondria and disrupt their function. Contractile proteins and calcium homeostasis In isolated cardiomyocyte, acute ethanol treatment induces a dose-dependent reduction of maximum shortening. This negative inotropic effect is significant at v ...
Conventional and biventricular pacing in patients with first
Conventional and biventricular pacing in patients with first

... 1.01, P ¼ 0.0650). Two other large studies have shown that a prolonged baseline PR interval is associated with an unfavourable CRT outcome.34,35 The predictive value of baseline and 3-month ECG variables were evaluated in the Cardiac Resynchronization in Heart Failure (CARE-HF) trial where HF patien ...
Function of heart anchored to diaphragm
Function of heart anchored to diaphragm

... 1415 However a study Member is a person research. The system further comprises be function of guys so. Associate Member An Associate Member is a person or entity who furnishes goods not. Been killed and that he was inspirational and some function of of the mates therefore it is. Accounts for php web ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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