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Acute Heart Failure
Acute Heart Failure

... Guidelines and Expert Consensus documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of Guid ...
Effect of precipitating factors of acute heart failure on readmission
Effect of precipitating factors of acute heart failure on readmission

... long-term survival in the overall population and in patients aged 75 years or younger. Methods and results Patients admitted with AHF (n = 755) included in the multicentre cohort ‘Biomarcoeurs’ were included in the study. Precipitating factors of AHF were classified in four main groups: acute coronar ...
EKG Paper ECG tracings are recorded on grid paper. The horizontal
EKG Paper ECG tracings are recorded on grid paper. The horizontal

... For ventricular rhythm, examine the R to R intervals on the EKG strip. Calipers or paper marks can be used to fix the distance for one R-R interval and then this distance can be compared to other R-R pairs. Within this web site, you will also be able to use virtual calipers. Are they regular, meanin ...
ecg interpretation
ecg interpretation

... Reduces the door to perfusion time in those candidates eligible for immediate reperfusion therapy. ECG changes may disappear after treatment of ischemia in the field and before arrival at the ED. This is not a problem if the 12 lead was performed with the first set of vital signs. If the patient has ...
Clinical guidance for the Management of patients with confirmed
Clinical guidance for the Management of patients with confirmed

... The purpose of this document is to provide guidance and a pathway for the treatment of patients with heart failure. The guidance is separated into two parts, the first addresses best practice in the clinical management of heart failure itself and the second focuses on management of symptoms commonly ...
Single Resting hsTnT Level Predicts Abnormal Myocardial Stress
Single Resting hsTnT Level Predicts Abnormal Myocardial Stress

... the intriguing hypothesis that these new assays may permit tracking of CAD development over time and also permit the detection of acute myocardial ischemia. This hypothesis has been supported by our previous results demonstrating that hsTnT assays permit improved detection of acute coronary syndrome ...
Amiodarone for resuscitation after out-of
Amiodarone for resuscitation after out-of

... due to ventricular fibrillation, claims at least 250,000 persons annually in the United States.1,2 The American Heart Association guidelines for advanced cardiac life support state that antiarrhythmic medications are “acceptable, probably helpful” for the treatment of ventricular fibrillation or pul ...
Echocardiography use in the diagnosis and management of cardiac
Echocardiography use in the diagnosis and management of cardiac

... stroke (particularly in stroke units) as a major cornerstone in the diagnostic work-up with a 1:3 ratio of TTE alone vs. TOE. This careful cardiodiagnostic approach appears to be justified even in patients with already known cerebral small vessel disease or artery-to-artery brain embolism from extra ...
Clinical Factors Associated With Persistent
Clinical Factors Associated With Persistent

... the important factors related to the course of PE after successful primary PTCA. Materials and Methods Patients We studied 391 consecutive patients admitted to the coronary care unit with their first ST-segment elevation AMI (April 1, 1988, to March 31, 2000) who underwent successful primary PTCA (⬍ ...
Akutes Koronarsyndrom - Kardiologie Update 2016
Akutes Koronarsyndrom - Kardiologie Update 2016

... management of STEMI, since the greatest benefit gained from reperfusion therapy occurs within the first 2–3 hours of symptom onset. The aim is to provide optimal care while minimizing delays, in order to improve clinical outcomes” ...


... ters. After initial assessment, all patients were started on a regimen of long-term oxygen therapy (LTOT). Follow-up consisted of medical examination, spirometry, and arterial blood gas analysis every 3 months. Pulmonary artery catheterization was repeated every 2 years. Results: Seventy-three subje ...
A V IRTUAL REALITY ELECTROCARDIOGRAPHY TEACHING TOOL John Ryan Carol O’Sullivan
A V IRTUAL REALITY ELECTROCARDIOGRAPHY TEACHING TOOL John Ryan Carol O’Sullivan

... several problematic areas. The most important part of the ECG wave is the ORS complex. The QRS complex is a waveform that correlates to the electrical flow through the bundle branches, from which heart-rate and many other parameters can be measured. Köhler et al [5] reviewed several different QRS de ...
Hemodynamics after Surgical Repair with Right Ventricle to
Hemodynamics after Surgical Repair with Right Ventricle to

... All conduits were inserted using the same surgical technique. A portion of the right ventricular free wall was excised and the bevelled end of the proximal end of the conduit was anastomosed to the right ventricle. The distal end of the conduit was also bevelled and anastomosed in an end-to-side man ...
Characterization of short QTc interval in Emergency Department
Characterization of short QTc interval in Emergency Department

... Only 3% (95%CI 1-5%) were on home medications which shortened QTc interval including <1% on Digoxin, the most commonly described cause of medication-induced short QTc. 67% (95%CI 62-73%) were discharged from the ED. There were no significant differences among the different length QTc groups with reg ...
Commotio cordis: an important cause of sudden cardiac
Commotio cordis: an important cause of sudden cardiac

030327 Cardiovascular Effects of Continuous
030327 Cardiovascular Effects of Continuous

... States, with annual costs of approximately $20 billion.1 Despite advances in pharmacologic therapy, morbidity, mortality, and rates of hospitalization for heart failure remain high.2-4 These data emphasize the importance of identifying all treatable conditions that could aggravate heart failure. One ...
WET LAB
WET LAB

... than SA node – ectopic foci - regions of spontaneous firing • Nodal Rhythm – if SA node is damaged, heart rate is set by AV node, 40 to 50 bpm • Intrinsic Ventricular Rhythm – if both SA and AV nodes are not functioning, rate set at 20 to 40 bpm – this requires pacemaker to sustain life ...
Ventricular arrhythmias
Ventricular arrhythmias

... puncture, Heparin to ACT of 280-350 12 F Stearable sheath (FlexCath) Stearable over the wire double lumen balloon catheter (Arctiv Front: 23-28 mm) Occlusion of each PV, freezing for 300 sec x 2. (temperature -40 to -60 C) Pacing w high output in SVC to capture phrenic nerve while freezing on the ri ...
MR-Imaging in diagnosis and follow-up post corrective
MR-Imaging in diagnosis and follow-up post corrective

... of MR imaging in the diagnosis of the different forms of congenital heart disease in pediatric patients. • An overview of common forms of CHD along with treatment procedures will be given. • Special interest is taken on technical issues and particularities in post surgical evaluation will be ...
Estrogen receptor alpha up-regulation
Estrogen receptor alpha up-regulation

... estrogen receptor ␣ (ER␣) has been claimed to be present and active in the plasma membranes of endothelial cells (10) and to interact with cytoplasmic proteins such as ␤-catenin and GSK3␤ (11). Cardiovascular estrogen receptors have been associated with the prevention of apoptosis (19), with the exp ...
Left Ventricular Pseudoaneurysm After Inferior Wall Myocardial
Left Ventricular Pseudoaneurysm After Inferior Wall Myocardial

... and most pseudoaneurysms are detected incidentally on imaging tests. When present, symptoms include recurrent chest pain and symptoms of hypotension.3 Examination findings include decreased heart sounds, pericardial friction rub, elevation of both left- and right-sided filling pressures, and sinus b ...
Preoperative Cardiac Evaluation for Noncardiac
Preoperative Cardiac Evaluation for Noncardiac

... compensated heart failure, significant arrhythmias, and severe valvular disease. Their presence precludes the performance of nonemergent surgery until the conditions are stabilized. The “lowest” risk category of clinical predictors do not inde­ pendently predict adverse cardiac outcomes, and these m ...
Diagnostic of Cardioembolic Stroke
Diagnostic of Cardioembolic Stroke

... Figure 1. WATCHMAN(r) Left Atrial Appendage System. The WATCHMAN device is comprised of a self-expanding nitinol frame structure with fixation barbs and a permeable polyester fabric that covers the atrial face of the device. The device is constrained in a 12F delivery catheter and is available in ...
- SlideBoom
- SlideBoom

... amount of blood both to the lungs and to the rest of the body .  PVC, the ventricles contract first  which means that circulation is inefficient  Single beat PVC arrhythmias do not usually pose a danger and can be asymptomatic in healthy ...
Identification of Premature Ventricular Contraction (PVC) of
Identification of Premature Ventricular Contraction (PVC) of

... system variable. The number of states [6] that can be displayed in phase space is called dimension or reconstruction dimension. It is usually symbolized by the letter d or E. From the given digitized data x(1), x(2), …, x(n) of the IHR or BBI, a matrix A is obtained with its two columns given by x(1 ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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